ES2079517T3 - Procedimiento para la obtencion de bencilcetonas. - Google Patents

Procedimiento para la obtencion de bencilcetonas.

Info

Publication number
ES2079517T3
ES2079517T3 ES91108882T ES91108882T ES2079517T3 ES 2079517 T3 ES2079517 T3 ES 2079517T3 ES 91108882 T ES91108882 T ES 91108882T ES 91108882 T ES91108882 T ES 91108882T ES 2079517 T3 ES2079517 T3 ES 2079517T3
Authority
ES
Spain
Prior art keywords
formula
elevated
diluent
atmosphere
temperatures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91108882T
Other languages
English (en)
Inventor
Thomas Dr Himmler
Udo Dr Kraatz
Wolfgang Dr Kramer
Klaus Dr Stroech
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2079517T3 publication Critical patent/ES2079517T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/227—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • C07C49/233—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/227—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • C07C49/233—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C07C49/235—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/527—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings
    • C07C49/567—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/527—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings
    • C07C49/577—Unsaturated compounds containing keto groups bound to rings other than six-membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/04—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D305/06—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Epoxy Compounds (AREA)

Abstract

SEGUN ESTE NUEVO METODO SE PUEDEN ELABORAR BENZILKETONEN DE LA FORMULA EN DONDE R ELEVADO 1, R (AL CUADRADO) , R ELEVADO 3, R ELEVADO 4, R ELEVADO 5, Y R ELEVADO 6 TIENEN EL SIGNIFICADO ARRIBA MENCIONADO, MEDIANTE LA TRANSFORMACION DE BENXILCLORIDOS DE LA FORMULA CON ACIDOCLORIDICO DE LA FORMULA EN PRESENCIA DE POLVO DE CINC Y DE UN CATALIZADOR DE PALLADIUM, ASI COMO EN PRESENCIA DE UN DILUENTE AL A) AL TRANSFORMAR EN UNA PRIMERA FASE UN BENZILCLORIDO DE LA FORMULA II CON UN EXCEDENTE DE POLVO DE CINC EN PRESENCIA DE UN DILUENTE A UNA TEMPERATURA DE 30 C Y DE 200 C BAJO LA ATMOSFERA DE GAS PROTECTOR, SEPARA EL EXCEDENTE DE POLVO DE CINC Y DESPUES, B) EN UNA SEGUNDA FASE SE TRANSFORMA EL DERIVADO DE BENCILO ORIGINADO DE LA FORMULA CON ACIDOCLORIDO DE LA FORMULA III EN PRESENCIA DE UN CATALIZADOR DE PALLADIUM Y EN PRESENCIA DE UN DILUENTE A TEMPERATURAS ENTRE 0 C Y 150 C BAJO LA ATMOSFERA DEL GAS PROTECTOR. SEGUN OTRO NUEVO METODO SE PUEDE ELABORAR 2-(2-CLOROBENCILO)-2-(1-CLORO -CICLOPROPILO)-OXIRAN EN TANTO EN CUANTO SE TRANSFORME 2-CLORBENCILO-1 -KETON-CLOROCICLOPROPILO CON TRIMETILSULFOXONIUM-CLORIDO A) EN PRESENCIA DE UN ALCOHOL Y EN PRESENCIA DE UN ALCALIMETALHIDROXID O DE UN ALCALIMETALALCOHOLATES O B) EN PRESENCIA DE TOLUOL O DE XILOL Y EN PRESENCIA DE HIDROXIDO SODICO ACUOSO O POTASA CAUSTICA A TEMPERATURAS DE 10 C Y DE 60 C.
ES91108882T 1990-06-13 1991-05-30 Procedimiento para la obtencion de bencilcetonas. Expired - Lifetime ES2079517T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4018926 1990-06-13
DE4030061A DE4030061A1 (de) 1990-06-13 1990-09-22 Verfahren zur herstellung von benzylketonen sowie verfahren zur herstellung eines oxiranes

Publications (1)

Publication Number Publication Date
ES2079517T3 true ES2079517T3 (es) 1996-01-16

Family

ID=25894116

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91108882T Expired - Lifetime ES2079517T3 (es) 1990-06-13 1991-05-30 Procedimiento para la obtencion de bencilcetonas.

Country Status (5)

Country Link
US (1) US5146001A (es)
EP (1) EP0461483B1 (es)
JP (1) JP3007188B2 (es)
DE (2) DE4030061A1 (es)
ES (1) ES2079517T3 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4018927A1 (de) * 1990-06-13 1991-12-19 Bayer Ag Azolyl-propanol-derivate
NZ241574A (en) * 1991-02-22 1993-08-26 Ishihara Sangyo Kaisha Substituted phenyl derivatives of hydrazone and pesticidal compositions
DE4208050A1 (de) * 1992-03-13 1993-09-23 Bayer Ag Azolylmethyl-fluorcyclopropyl-derivate
DE19511861A1 (de) * 1995-03-31 1996-10-02 Basf Ag Verfahren zur Herstellung von a-Chloralkylarylketonen
EP1609774A1 (en) * 2004-06-22 2005-12-28 Dainippon Ink And Chemicals, Inc. Fluorine atom containing benzyl ketone compound and process for producing the same
JP2016003226A (ja) * 2014-06-19 2016-01-12 株式会社クレハ シクロペンタノール誘導体の製造方法
CN108358860B (zh) * 2018-02-08 2023-11-21 辽宁众辉生物科技有限公司 一种高收率合成丙硫菌唑的方法
CN109369549A (zh) * 2018-12-29 2019-02-22 安徽久易农业股份有限公司 一种丙硫菌唑的制备方法
CN109651298B (zh) * 2019-02-15 2020-11-27 利民化学有限责任公司 2-(2-氯苄基)-2-(1-氯甲基)环氧乙烷的制备方法
CN110627627A (zh) * 2019-09-20 2019-12-31 江苏澄扬作物科技有限公司 1-（1-氯环丙基）-2-（2-氯苯基）乙酮的制备方法及其中间体
CN112851534B (zh) * 2021-02-03 2024-01-26 安徽丰原生物技术股份有限公司 一种d-天门冬氨酸结晶方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2845462A (en) * 1953-03-20 1958-07-29 Ortho Pharma Corp Synthesis of compounds having vitamin a activity
US2855397A (en) * 1955-11-28 1958-10-07 Metal & Thermit Corp Process of reacting carbon-containing compounds with specified grignards
US3080324A (en) * 1960-08-01 1963-03-05 Cincinnati Milling Machine Co Grignard reagents
GB8302498D0 (en) * 1983-01-29 1983-03-02 Pfizer Ltd Antifungal agents
DE3315510A1 (de) * 1983-04-29 1984-10-31 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von oxiranen
DE3315619A1 (de) * 1983-04-29 1984-10-31 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von oxiranen
DE3315524A1 (de) * 1983-04-29 1984-10-31 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von oxiranen
US4989954A (en) * 1987-10-09 1991-02-05 Matsushita Electric Industrial Co., Ltd. Projection type liquid cyrstal display device

Also Published As

Publication number Publication date
US5146001A (en) 1992-09-08
EP0461483A2 (de) 1991-12-18
EP0461483A3 (es) 1994-03-23
DE4030061A1 (de) 1991-12-19
JPH04230232A (ja) 1992-08-19
JP3007188B2 (ja) 2000-02-07
EP0461483B1 (de) 1995-11-02
DE59106800D1 (de) 1995-12-07

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