ES2077853T3 - Procedimiento para la produccion de peptidos. - Google Patents

Procedimiento para la produccion de peptidos.

Info

Publication number
ES2077853T3
ES2077853T3 ES91909262T ES91909262T ES2077853T3 ES 2077853 T3 ES2077853 T3 ES 2077853T3 ES 91909262 T ES91909262 T ES 91909262T ES 91909262 T ES91909262 T ES 91909262T ES 2077853 T3 ES2077853 T3 ES 2077853T3
Authority
ES
Spain
Prior art keywords
peptides
pct
sec
amino acid
date
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91909262T
Other languages
English (en)
Inventor
Hans-Dieter Jakubke
Matthias Schuster
Aavo Aaviksaar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2077853T3 publication Critical patent/ES2077853T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C07K1/023—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution using racemisation inhibiting agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PEPTIDOS, SINTESIS DE PEPTIDOS, ENZIMAS, ENZIMAS DE TRANSFERENCIA DE ACILOS, SERINPROTEASAS, RENDIMIENTO DE SINTESIS. LA INVENCION CONCIERNE A UN PROCEDIMIENTO PARA LA PRODUCCION DE PEPTIDOS QUIRALES UNITARIOS. EL OBJETIVO DE LA INVENCION ES LA REPRESENTACION DE PEPTIDOS QUIRALES UNITARIOS CON AYUDA DE ENZIMAS PROTEOLITICOS. LA TAREA CONSISTE EN TRANSFORMAR ESTER ALQUILO DE ACIDO N IVADOS DE AMINOACIDOS O PEPTIDOS. LA TAREA SE SOLUCIONA DE MANERA QUE SE TRANSFORMA UN ESTER DEL ACIDO N DERIVADO APROPIADO DEL AMINOACIDO O PEPTIDO CON UN GRUPO N TERMINAL ALFA DA BAJO CATALISIS DE UNA SERINPROTEASA O CISTEINPROTEASA.
ES91909262T 1990-06-13 1991-05-10 Procedimiento para la produccion de peptidos. Expired - Lifetime ES2077853T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DD90341603A DD295165A5 (de) 1990-06-13 1990-06-13 Verfahren zur herstellung von peptiden

Publications (1)

Publication Number Publication Date
ES2077853T3 true ES2077853T3 (es) 1995-12-01

Family

ID=5619138

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91909262T Expired - Lifetime ES2077853T3 (es) 1990-06-13 1991-05-10 Procedimiento para la produccion de peptidos.

Country Status (12)

Country Link
US (1) US5350682A (es)
EP (1) EP0534992B1 (es)
JP (1) JP3122458B2 (es)
AT (1) ATE127847T1 (es)
AU (1) AU644171B2 (es)
CA (1) CA2082799C (es)
DD (1) DD295165A5 (es)
DE (1) DE59106487D1 (es)
DK (1) DK0534992T3 (es)
ES (1) ES2077853T3 (es)
GR (1) GR3017746T3 (es)
WO (1) WO1991019811A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE175721T1 (de) * 1993-04-23 1999-01-15 Degussa Verfahren zur herstellung von peptiden und verwendung
DE4423724A1 (de) * 1994-07-08 1996-01-11 Degussa Kinetisch kontrolliertes Verfahren zur enzymatischen Herstellung von Peptiden
AU1112597A (en) * 1996-07-25 1998-02-20 Firma "Nika-Universal" Binary techniques for producing biologically active peptides
DE10047857B4 (de) * 2000-09-27 2004-11-18 Universität Leipzig Verfahren zur selektiven biokatalytischen Modifizierung von Peptiden und Proteinen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2857828C2 (es) * 1977-01-27 1990-06-07 Toyo Soda Mfg. Co., Ltd., Shinnanyo, Yamaguchi, Jp
US4935355A (en) * 1986-04-15 1990-06-19 Synthetech, Inc. Preparation of dipeptides

Also Published As

Publication number Publication date
EP0534992A1 (de) 1993-04-07
AU644171B2 (en) 1993-12-02
CA2082799A1 (en) 1991-12-14
DK0534992T3 (da) 1996-01-22
EP0534992B1 (de) 1995-09-13
GR3017746T3 (en) 1996-01-31
DD295165A5 (de) 1991-10-24
JP3122458B2 (ja) 2001-01-09
WO1991019811A1 (de) 1991-12-26
ATE127847T1 (de) 1995-09-15
JPH05507403A (ja) 1993-10-28
DE59106487D1 (de) 1995-10-19
US5350682A (en) 1994-09-27
CA2082799C (en) 2000-07-04
AU7783191A (en) 1992-01-07

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