ES2070658A1 - Dispositivo para diagnosticar y distinguir el dolor toracico en su fase inicial en pacientes con riesgo de angina o infarto de miocardio. - Google Patents

Dispositivo para diagnosticar y distinguir el dolor toracico en su fase inicial en pacientes con riesgo de angina o infarto de miocardio.

Info

Publication number
ES2070658A1
ES2070658A1 ES09102146A ES9102146A ES2070658A1 ES 2070658 A1 ES2070658 A1 ES 2070658A1 ES 09102146 A ES09102146 A ES 09102146A ES 9102146 A ES9102146 A ES 9102146A ES 2070658 A1 ES2070658 A1 ES 2070658A1
Authority
ES
Spain
Prior art keywords
chest pain
patient
early onset
diagnosing
diagnostic kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09102146A
Other languages
English (en)
Other versions
ES2070658B1 (es
Inventor
George Jackowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spectral Diagnostics Inc Canada
Original Assignee
Spectral Diagnostics Inc Canada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4146144&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2070658(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Spectral Diagnostics Inc Canada filed Critical Spectral Diagnostics Inc Canada
Publication of ES2070658A1 publication Critical patent/ES2070658A1/es
Application granted granted Critical
Publication of ES2070658B1 publication Critical patent/ES2070658B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/97—Test strip or test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/973—Simultaneous determination of more than one analyte
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

DISPOSITIVO PARA DIAGNOSTICAR Y DISTINGUIR EL DOLOR TORACICO EN SU FASE INICIAL EN PACIENTES CON RIESGO DE ANGINA O INFARTO DE MIOCARDIO. COMPRENDE UN RECEPTACULO PARA RECIBIR Y RETENER UNA MUESTRA DE SANGRE O SUERO DEL PACIENTE Y POR LO MENOS TRES ANTICUERPOS MONOCLONALES O POLICLONARES EN SUSPENSION EN UN VEHICULO. CADA ANTICUERPO ES COMPLEMENTARIO A UNA PROTEINA DIFERENTE LIBERADA POR EL MUSCULO CARDIACO DURANTE LAS FASES INICIALES DE UN INFARTO DE MIOCARDIO Y TIENE REACTIVOS CORRESPONDIENTES QUE RESPONDEN INDEPENDIENTEMENTE A CADA ANTICUERPO QUE HACE REACCIONAR A LA PROTEINA COMPLEMENTARIA. LA RESPUESTA COMBINADA DE LOS REACTIVOS INDICA EL ESTADO DE DIAGNOSTICO DEL PACIENTE.
ES09102146A 1990-10-12 1991-09-30 Dispositivo para diagnosticar y distinguir el dolor toracico en su fase inicial en pacientes con riesgo de angina o infarto de miocardio. Expired - Fee Related ES2070658B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002027434A CA2027434C (en) 1990-10-12 1990-10-12 Diagnostic kit for diagnosing and distinguishing chest pain in early onset thereof

Publications (2)

Publication Number Publication Date
ES2070658A1 true ES2070658A1 (es) 1995-06-01
ES2070658B1 ES2070658B1 (es) 1995-12-16

Family

ID=4146144

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09102146A Expired - Fee Related ES2070658B1 (es) 1990-10-12 1991-09-30 Dispositivo para diagnosticar y distinguir el dolor toracico en su fase inicial en pacientes con riesgo de angina o infarto de miocardio.

Country Status (15)

Country Link
US (1) US5290678A (es)
JP (1) JP2628421B2 (es)
KR (1) KR0167564B1 (es)
CN (1) CN1036155C (es)
AR (1) AR247634A1 (es)
BE (1) BE1004994A5 (es)
BR (1) BR9104431A (es)
CA (1) CA2027434C (es)
DE (1) DE4122886C2 (es)
ES (1) ES2070658B1 (es)
FR (1) FR2667944B1 (es)
GB (1) GB2248688B (es)
IT (1) IT1251682B (es)
MX (1) MX9101550A (es)
NZ (1) NZ239938A (es)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5604105B1 (en) * 1990-10-12 1999-08-24 Spectral Diagnostics Inc Method and device for diagnosingand distinguishing chest pain in early onset thereof
US5710008B1 (en) * 1990-10-12 1999-09-07 Spectral Diagnostics Inc Method and device for diagnosing and distinguishing chest pain in early onset thereof
WO1994003807A1 (en) * 1992-08-03 1994-02-17 Gec-Marconi Limited Separation method
US5807752A (en) * 1992-09-11 1998-09-15 Boehringer Mannheim Corporation Assay using an unblocked solid phase with immobilized analyte binding partner
DE4243648A1 (de) * 1992-12-23 1994-07-07 Boehringer Mannheim Gmbh Verfahren zur Bestimmung von Herzmuskelnekrosen mittels Antikörper gegen das N-terminale Troponin I-Peptid
FR2701954B1 (fr) * 1993-02-23 1995-07-07 Pasteur Sanofi Diagnostics Composition stabilisée de troponine pour immunoessais et procédé de stabilisation de troponine pour immunoessais.
JPH09503050A (ja) * 1993-05-17 1997-03-25 フォートロン バイオサイエンス インク． 心臓トロポニン▲ｉ▼のアッセイ
CA2130280C (en) * 1993-08-24 1999-08-31 Lilian Lee Method for purification of cardiac troponin i
US5658801A (en) * 1994-05-03 1997-08-19 Spectral Diagnostics Inc. Medical test kit
US5573957A (en) * 1994-09-28 1996-11-12 Spectral Diagnostics, Inc. Monoclonal antibody to human cardiac myoglobin
WO1996010076A1 (en) * 1994-09-28 1996-04-04 Spectral Diagnostics Inc. A monoclonal antibody to human cardiac troponin i
US5702905A (en) * 1994-09-28 1997-12-30 Spectral Diagnostics Monoclonal antibody to human ventricular myosin light chains
US5795725A (en) * 1995-04-18 1998-08-18 Biosite Diagnostics Incorporated Methods for the assay of troponin I and T and selection of antibodies for use in immunoassays
ATE281648T1 (de) 1995-04-18 2004-11-15 Biosite Diagnostics Inc Verfahren zum assay von troponin i und t und komplexen von troponin i und t und auswahl von antikörpern zur verwendung in immunoassays
US6991907B1 (en) 1995-04-18 2006-01-31 Biosite, Inc. Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays
US6627404B1 (en) * 1995-04-18 2003-09-30 Biosite, Inc. Methods for improving the recovery of troponin I and T in membranes, filters and vessels
FR2734267B1 (fr) * 1995-05-16 1997-08-01 Pasteur Sanofi Diagnostics Composition stabilisee de troponine pour immunoessais et procede de preparation d'une telle composition stabilisee
ATE279876T1 (de) * 1995-08-17 2004-11-15 Univ Duke Verfahren zur feststellung von reperfusion nach thrombolytischer therapie
AU6764196A (en) * 1995-08-31 1997-03-19 First Medical, Inc. Methods and antibodies for detecting creatine kinase
US6611634B2 (en) 1996-03-19 2003-08-26 University Of Utah Research Foundation Lens and associatable flow cell
JPH09304393A (ja) * 1996-05-15 1997-11-28 Ind Technol Res Inst 急性心筋梗塞診断キット
US5690103A (en) * 1996-06-20 1997-11-25 Groth; Torgny Lars Detection/exclusion of acute myocardial infarction using neural network analysis of measurements of biochemical markers
US6156521A (en) * 1997-12-19 2000-12-05 Biosite Diagnostics, Inc. Methods for the recovery and measurement of troponin complexes
US5834210A (en) * 1997-05-23 1998-11-10 Spectral Diagnostics, Inc. Stable troponin subunits and complexes
US6248869B1 (en) 1997-05-29 2001-06-19 Medical Analysis Systems, Inc. Troponin I forms and use of the same
CA2293718A1 (en) 1997-06-10 1998-12-17 Medlyte Diagnostics, Inc. Methods for early detection of heart disease
US5961470A (en) * 1997-07-09 1999-10-05 Wagner; David A. Breath test for assessing hepatic function
US7384751B1 (en) 1997-07-16 2008-06-10 Queen's University At Kingston Methods of diagnosing muscle damage
US6222619B1 (en) 1997-09-18 2001-04-24 University Of Utah Research Foundation Diagnostic device and method
US6077676A (en) * 1997-12-18 2000-06-20 Spectral Diagnostics, Inc. Single-chain polypeptides comprising troponin I and troponin C
US6475785B1 (en) 1997-12-18 2002-11-05 Spectral Diagnostics, Inc. Single-chain polypeptides comprising troponin I N-terminal fragments and troponin C
US6214629B1 (en) 1998-08-06 2001-04-10 Spectral Diagnostics, Inc. Analytical test device and method for use in medical diagnoses
US6410341B1 (en) 1998-08-06 2002-06-25 Spectral Diagnostics, Inc. Analytical test device and method for use in medical diagnoses
US6171870B1 (en) 1998-08-06 2001-01-09 Spectral Diagnostics, Inc. Analytical test device and method for use in medical diagnoses
US6432126B1 (en) 1998-09-30 2002-08-13 C.R. Bard, Inc. Flexible vascular inducing implants
US7070937B1 (en) 1998-10-02 2006-07-04 Ischemia Technologies, Inc. Marker useful for detection and measurement of free radical damage and method
US7449338B2 (en) * 1998-10-02 2008-11-11 Ischemia Technologies, Inc. Tests for the rapid evaluation of ischemic states and kits
US7282369B2 (en) * 1998-10-02 2007-10-16 Ischemia Technologies, Inc. Tests for the rapid evaluation of ischemic states and kits
US20030215359A1 (en) * 1998-10-02 2003-11-20 Ischemia Technologies, Inc. Tests for the rapid evaluation of ischemic states and kits
US20050142613A1 (en) * 1998-10-02 2005-06-30 David Bar-Or Test for the rapid evaluation of ischemic states and kits
US6475743B1 (en) 1998-10-02 2002-11-05 Ischemia Technologies, Inc. Marker useful for detection and measurement of free radical damage and method
GB9827411D0 (en) 1998-12-11 1999-02-03 Axis Biochemicals Asa Dipstick assay
CA2263063C (en) * 1999-02-26 2004-08-10 Skye Pharmatech Incorporated Method for diagnosing and distinguishing stroke and diagnostic devices for use therein
US6780606B1 (en) * 1999-02-26 2004-08-24 Synx Pharma, Inc. Method for diagnosing and distinguishing stroke and diagnostic devices for use therein
US7618782B1 (en) 1999-10-18 2009-11-17 Queen's University At Kingston Methods of diagnosing muscle damage
GB9929140D0 (en) * 1999-12-10 2000-02-02 Univ Geneve Diagnostic assay for stroke
US7078486B2 (en) * 1999-12-10 2006-07-18 Spectral Diagnostics, Inc. Single-chain polypeptides comprising troponin I and troponin C
JP4575635B2 (ja) * 2000-03-10 2010-11-04 ユニヴェルシテ ドゥ ジュネーブ 伝染性海綿状脳症のための診断アッセイ
US7204847B1 (en) 2000-07-28 2007-04-17 C. R. Bard, Inc. Implant anchor systems
AU9215101A (en) 2000-08-17 2002-02-25 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US6858590B2 (en) * 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US6680059B2 (en) * 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7022830B2 (en) * 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
WO2002016947A2 (en) * 2000-08-21 2002-02-28 Queen's University At Kingston Methods and kits for separation and detection of proteins in biological samples
US6673562B2 (en) 2000-08-24 2004-01-06 Spectral Diagnostics, Inc. Differential immunoassay
WO2003016910A1 (en) * 2001-08-20 2003-02-27 Biosite, Inc. Diagnostic markers of stroke and cerebral injury and methods of use thereof
US20030199000A1 (en) * 2001-08-20 2003-10-23 Valkirs Gunars E. Diagnostic markers of stroke and cerebral injury and methods of use thereof
US20040176914A1 (en) * 2001-04-13 2004-09-09 Biosite Incorporated Methods and compositions for measuring biologically active natriuretic peptides and for improving their therapeutic potential
WO2002089657A2 (en) * 2001-05-04 2002-11-14 Biosite, Inc. Diagnostic markers of acute coronary syndromes and methods of use thereof
US7524635B2 (en) * 2003-04-17 2009-04-28 Biosite Incorporated Methods and compositions for measuring natriuretic peptides and uses thereof
US7713705B2 (en) 2002-12-24 2010-05-11 Biosite, Inc. Markers for differential diagnosis and methods of use thereof
US7632647B2 (en) * 2001-04-13 2009-12-15 Biosite Incorporated Use of B-type natriuretic peptide as a prognostic indicator in acute coronary syndromes
US20030219734A1 (en) * 2001-04-13 2003-11-27 Biosite Incorporated Polypeptides related to natriuretic peptides and methods of their identification and use
US20040219509A1 (en) * 2001-08-20 2004-11-04 Biosite, Inc. Diagnostic markers of stroke and cerebral injury and methods of use thereof
US7608406B2 (en) * 2001-08-20 2009-10-27 Biosite, Inc. Diagnostic markers of stroke and cerebral injury and methods of use thereof
US20040209307A1 (en) * 2001-08-20 2004-10-21 Biosite Incorporated Diagnostic markers of stroke and cerebral injury and methods of use thereof
US6461828B1 (en) 2001-09-04 2002-10-08 Syn X Pharma Conjunctive analysis of biological marker expression for diagnosing organ failure
US20050130245A1 (en) * 2001-09-17 2005-06-16 Syn X Pharma, Inc. Diagnosis and treatment of early pre-type-1 diabetes utilizing neuronal proteins
US20030054414A1 (en) * 2001-09-17 2003-03-20 George Jackowski Diagnosis and treatment of early pre-type-1 diabetes utilizing glial fibrillary acidic protein
US20040067512A1 (en) * 2001-11-09 2004-04-08 Neurogenetics, Inc. Single nucleotide polymorphisms and mutations on Alpha-2-Macroglobulin
AU2002364894A1 (en) * 2001-11-09 2003-06-30 Neurogenetics, Inc. Single nucleotide polymorphisms and mutations on alpha-2-macroglobulin
US20050014198A1 (en) * 2002-07-11 2005-01-20 Leong Ng Assays and kits for detecting and monitoring heart disease
GB0216191D0 (en) * 2002-07-11 2002-08-21 Univ Leicester Plasma urotensin in human heart failure
GB0224425D0 (en) * 2002-10-21 2002-11-27 Univ Leicester Method for prediction of cardiac disease
JP4727997B2 (ja) * 2005-01-12 2011-07-20 シスメックス株式会社 イムノクロマトグラフィー用キット
US7968697B2 (en) * 2005-05-25 2011-06-28 Chrontech Pharma Ab Hepatitis C virus non-structural NS3/4A fusion gene
CA2612450C (en) * 2005-06-28 2014-04-29 Zbx Corporation Membrane array and analytical device
AU2007284651B2 (en) * 2006-08-09 2014-03-20 Institute For Systems Biology Organ-specific proteins and methods of their use
EP2185195A2 (en) * 2007-08-16 2010-05-19 Tripep Ab Immunogen platform
US20090214593A1 (en) * 2007-08-16 2009-08-27 Tripep Ab Immunogen platform
US20110076697A1 (en) * 2009-04-28 2011-03-31 Innovative Laboratory Technologies, Inc. Lateral-flow immuno-chromatographic assay devices
EP2427056A4 (en) * 2009-05-07 2012-08-22 Univ Cincinnati METHODS FOR PREVENTING ISCHEMIC LESION BY STIMULATION OF PERIPHERAL NICE PERIPHERAL
US20110306148A1 (en) 2010-06-14 2011-12-15 Siemens Healthcare Diagnostics Inc. Composition for use as an assay reagent
WO2012011074A2 (en) 2010-07-22 2012-01-26 Hach Company Lab-on-a-chip for alkalinity analysis
WO2012060845A1 (en) * 2010-11-05 2012-05-10 University Of Cincinnati Methods of preventing ischemic injury using peripheral nociceptive stimulation
CN103917638A (zh) 2011-09-08 2014-07-09 Nexusdx股份有限公司 多级分析物检定
US9180449B2 (en) 2012-06-12 2015-11-10 Hach Company Mobile water analysis
USD768872S1 (en) 2012-12-12 2016-10-11 Hach Company Cuvette for a water analysis instrument

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857453A (en) * 1987-04-07 1989-08-15 Syntex (U.S.A.) Inc. Immunoassay device
EP0384130A2 (en) * 1987-07-21 1990-08-29 International Immunoassay Laboratories, Inc. Myocardial infarction immunoassay

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5411231A (en) * 1977-06-27 1979-01-27 Daiichi Radioisotope Lab Production of purified antiimyoglobin antibody and quantitative analysis of myoglobin
US4353982A (en) * 1980-04-10 1982-10-12 Hoffmann-La Roche Inc. Immunochemical assay for creatine kinase-MB isoenzyme
US4624916A (en) * 1984-04-06 1986-11-25 International Immunoassay Laboratories, Inc. Process and composition for the rapid quantitation of small levels of creative kinase-MB isoenzyme
US4999285A (en) * 1984-11-15 1991-03-12 Syntex (U.S.A.) Inc. Chromatographic cassette
IE59210B1 (en) * 1985-11-14 1994-01-26 Univ Washington Creatine kinase mb determination method
JPS62151192A (ja) * 1985-12-24 1987-07-06 Denka Seiken Co Ltd ヒト心筋ミオシン軽鎖に対する単一クロ−ン抗体
DE3640318A1 (de) * 1986-11-26 1988-06-09 Boehringer Mannheim Gmbh Verfahren und testtraeger zur bestimmung eines analyten
DE3707746A1 (de) * 1987-03-11 1988-09-22 Boehringer Mannheim Gmbh Spezifische antikoerper gegen herzmuskelmyosin-leichtketten, ihre herstellung und verwendung in einem reagenz zur bestimmung von herzmuskelmyosin-leichtketten
CA1303983C (en) * 1987-03-27 1992-06-23 Robert W. Rosenstein Solid phase assay
CA1340557C (en) * 1987-04-09 1999-05-25 Christine A. Vitkauskas Ckmb assay and monoclonal antibodies for use in same
CA1313616C (en) * 1987-06-01 1993-02-16 Robert B. Sargeant Lateral flow, non-bibulous membrane protocols
JPS6461664A (en) * 1987-08-18 1989-03-08 Maikurobaiorojikaru Res Corp Solid phase enzyme immunological inspection system and processing therefor
JPH01233298A (ja) * 1988-03-11 1989-09-19 Boehringer Mannheim Gmbh 抗体、その製造法、ｈｍｌｃを測定するための試薬、ならびにモノクローナル抗体
DE3814370A1 (de) * 1988-04-28 1989-11-09 Boehringer Mannheim Gmbh Testtraeger fuer die analyse einer probenfluessigkeit, verfahren zur durchfuehrung einer solchen analyse und herstellungsverfahren
JPH01302162A (ja) * 1988-05-31 1989-12-06 Tosoh Corp ヒトミオグロビンの測定方法
US5087556A (en) * 1989-05-17 1992-02-11 Actimed Laboratories, Inc. Method for quantitative analysis of body fluid constituents
GB8916718D0 (en) * 1989-07-21 1989-09-06 Vioclone Biolog Inc Use of creatine kinase and its isozyme ck-mb and human ventricular myosin light chain 1 in the diagnosis of heart failure

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4857453A (en) * 1987-04-07 1989-08-15 Syntex (U.S.A.) Inc. Immunoassay device
EP0384130A2 (en) * 1987-07-21 1990-08-29 International Immunoassay Laboratories, Inc. Myocardial infarction immunoassay

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BAADSGAARD, O. et al., "Scand.J.Clin.Invest.", 1984, vol. 44, pßginas 679-682 *
CUMMINS, B. et al., "Amer.Heart J.", junio, 1987, vol. 113, n‘ 6, pßginas 1333-1344 *
HOBERG, E. et al., "Eur. Heart J.", 1987, vol. 8, pßginas 989-994 *
KATUS, H.A. et al., "Am.J.Cardiol." noviembre, 1984, vol. 54, pßginas 964-970 *
REESE, L. et al., "CMA J.", junio, 1981, vol. 124, pßginas 1585-1587 *
SPEICHER, et al., "Choosing Effective Laboratory Tests", Philadelphia, Saunders Co., 1983, pßginas 155-163 *

Also Published As

Publication number Publication date
AU8475791A (en) 1992-04-16
GB2248688A (en) 1992-04-15
GB9111965D0 (en) 1991-07-24
ITMI912687A1 (it) 1993-04-10
ITMI912687A0 (it) 1991-10-10
CA2027434A1 (en) 1992-04-13
US5290678A (en) 1994-03-01
GB2248688B (en) 1995-07-12
AR247634A1 (es) 1995-01-31
CN1060533A (zh) 1992-04-22
IT1251682B (it) 1995-05-19
KR0167564B1 (ko) 1999-03-30
JP2628421B2 (ja) 1997-07-09
AU654672B2 (en) 1994-11-17
NZ239938A (en) 1994-03-25
BE1004994A5 (fr) 1993-03-16
FR2667944B1 (fr) 1993-07-30
FR2667944A1 (fr) 1992-04-17
CN1036155C (zh) 1997-10-15
MX9101550A (es) 1992-07-08
CA2027434C (en) 1999-01-05
BR9104431A (pt) 1992-06-09
ES2070658B1 (es) 1995-12-16
DE4122886C2 (de) 2000-03-02
JPH04258765A (ja) 1992-09-14
KR920008491A (ko) 1992-05-28
DE4122886A1 (de) 1992-04-16

Similar Documents

Publication Publication Date Title
ES2070658A1 (es) Dispositivo para diagnosticar y distinguir el dolor toracico en su fase inicial en pacientes con riesgo de angina o infarto de miocardio.
MX9707889A (es) Metodo y dispositivo para diagnosticar y distinguir dolor de pecho en inicio temprano del mismo.
ES2009939A6 (es) Un inmunoensayo para la deteccion simultanea de antigenos yno anticuerpos en una muestra a ensayar de un fluido fisiologico.
US5726061A (en) Method of diagnosing and monitoring colorectal cancer
JPH0588421B2 (es)
Farrell et al. A survey for circulating immune complexes in patients with acute myocardial infarction: use of a C1q‐binding assay with soluble protein A as indicator
CA1340973C (en) Immunometric assay kit and method applicable to whole cells
DE69333076D1 (de) Test und behandlung von demyelinierenden krankheiten wie multiple sklerosis
Ohta et al. Anti-skeletal muscle antibodies in the sera from myasthenic patients with thymoma: identification of anti-myosin, actomyosin, actin, and α-actinin antibodies by a solid-phase radioimmunoassay and a western blotting analysis
JP3055789B2 (ja) 骨由来アルカリホスファターゼの検定法
ES2033823T3 (es) Ensayo en cuanto a cancer de mama humano.
US6451980B1 (en) Signal enhancement of bispecific antibody-polymer probe for immunoassay use
Kelly et al. Antibody to discrete areas of the brain in normal individuals and patients with schizophrenia.
DE59602091D1 (de) Verwendung von polyklonalen humanen anti-htg-autoantikörpern als reagenz für die klinische diagnostik von schilddrüsen-autoimmunerkrankungen sowie reagenziensatz für eine bestimmung von anti-htg-autoantikörpern in patientenseren
Igietseme et al. Quantitative measurement of T-lymphocyte activation by an enzyme-linked immunosorbent assay (ELISA) detecting interleukin-2 receptor expression
SU1425549A1 (ru) Способ радиоиммунологического определени антигенов
AU8189891A (en) Methods for diagnosis of complex urolithiasis and prognosis of urolithiasis
SU1505193A1 (ru) Способ диагностики гипертонической болезни
US5593898A (en) Diagnostic method for the immunological determination of NCAM
Aarli Demonstration of antibodies to muscle by absorption of rheumatoid factor
Mathiot et al. Evaluation of 12 kits for HIV antibody detection with a reference panel of African sera
RU93010134A (ru) Способ прогнозирования течения острого инфаркта миокарда
Lawless et al. ELISA assay for colon cancer
JPH10311832A (ja) サンドイッチ測定法および肝疾患の鑑別法
RU96121426A (ru) Способ диагностики опийной наркомании

Legal Events

Date Code Title Description
FD2A Announcement of lapse in spain

Effective date: 20111108