ES2070488T3 - Procedimiento para la deteccion de enfermedades malignas. - Google Patents
Procedimiento para la deteccion de enfermedades malignas.Info
- Publication number
- ES2070488T3 ES2070488T3 ES91902191T ES91902191T ES2070488T3 ES 2070488 T3 ES2070488 T3 ES 2070488T3 ES 91902191 T ES91902191 T ES 91902191T ES 91902191 T ES91902191 T ES 91902191T ES 2070488 T3 ES2070488 T3 ES 2070488T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- receptors
- detection
- malignant diseases
- date jul
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57496—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving intracellular compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/828—Cancer
Abstract
PARA DETECTAR ENFERMEDADES MALIGNAS SE INCUBA UNA MUESTRA DE UN LIQUIDO DEL CUERPO CON DOS RECEPTORES, R SUB 1 Y R SUB 2, POR LO MENOS Y SE PRODUCE UNA VARIACION EN LA SEÑAL ENLAZANDO POR LO MENOS LOS RECEPTORES R SUB 1 Y R SUB 2 A UNA SUSTANCIA QUE VA A SER DETECTADA EN LA SOLUCION DE MUESTRA. UNO DE LOS DOS RECEPTORES CONTIENE UN ANTICUERPO MONOCLONAL QUE ENLAZA LA SECUENCIA AMINOACIDA (291 A 335) DE CITOCESATINA (19) Y EL OTRO RECEPTOR CONTIENE UN ANTICUERPO MONOCLONAL QUE ENLAZA LA SECUENCIA AMINOACIDA (346 A 367) DE CITOCERATINA (19) Y DETERMINA LA VARIACION DE LA SEÑAL DEBIDA AL ENLACE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3942999A DE3942999C2 (de) | 1989-12-27 | 1989-12-27 | Verfahren zum Nachweis von malignen Erkrankungen |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2070488T3 true ES2070488T3 (es) | 1995-06-01 |
ES2070488T5 ES2070488T5 (es) | 2002-07-01 |
Family
ID=6396458
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91902191T Expired - Lifetime ES2070488T5 (es) | 1989-12-27 | 1990-12-27 | Procedimiento para la diagnosis de enfermedades tumorales. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5288614A (es) |
EP (1) | EP0460190B2 (es) |
JP (1) | JPH082919B2 (es) |
AT (1) | ATE120550T1 (es) |
CA (1) | CA2046888A1 (es) |
DE (2) | DE3942999C2 (es) |
DK (1) | DK0460190T3 (es) |
ES (1) | ES2070488T5 (es) |
WO (1) | WO1991010139A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4208422A1 (de) * | 1992-03-16 | 1993-09-30 | Boehringer Mannheim Gmbh | Verfahren zum Nachweis von Mikrometastasen ekto- oder entodermaler Tumoren |
US5547928A (en) * | 1993-12-17 | 1996-08-20 | Matritech, Inc. | Methods and compositions for the detection of colon cancers |
WO1999014372A1 (en) * | 1997-09-15 | 1999-03-25 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the urinary tract |
DE19855819C2 (de) * | 1998-12-03 | 2001-02-15 | Roche Diagnostics Gmbh | Stabilisierung von Cytokeratin enthaltenden Kalibratoren |
US8980568B2 (en) | 2001-10-11 | 2015-03-17 | Aviva Biosciences Corporation | Methods and compositions for detecting non-hematopoietic cells from a blood sample |
US8986944B2 (en) | 2001-10-11 | 2015-03-24 | Aviva Biosciences Corporation | Methods and compositions for separating rare cells from fluid samples |
JPWO2005043166A1 (ja) * | 2003-10-30 | 2007-11-29 | シスメックス株式会社 | 子宮腺癌の診断薬及び腺癌細胞の検出方法 |
WO2007076439A2 (en) * | 2005-12-22 | 2007-07-05 | Abbott Laboratories | Methods and marker combinations for screening for predisposition to lung cancer |
CN101583722A (zh) * | 2006-07-14 | 2009-11-18 | 阿维瓦生物科学股份有限公司 | 从生物学样品检测稀有细胞的方法和组合物 |
ATE522813T1 (de) * | 2006-09-07 | 2011-09-15 | Universitaetsklinikum Hamburg | Verfahren für den nachweis karzinomatöser epithelzellen mittels freigesetzter zytokeratine als marker für diese zellen |
CN103476428B (zh) | 2010-09-09 | 2016-10-26 | 北京同为时代生物技术有限公司 | 用于诊断上皮源性癌症的血液标志物及其单克隆抗体 |
JP6352909B2 (ja) | 2012-06-27 | 2018-07-04 | バーグ エルエルシー | 前立腺癌の診断および処置におけるマーカーの使用 |
KR102280473B1 (ko) * | 2014-02-05 | 2021-07-22 | 후지레비오 디아그노스틱스 에이비 | 악성 신생물 질환의 검출을 위한 조성물 및 방법 |
CA2970143A1 (en) | 2014-12-08 | 2016-06-16 | Berg Llc | Use of markers including filamin a in the diagnosis and treatment of prostate cancer |
JP6637290B2 (ja) * | 2015-11-05 | 2020-01-29 | 武 永安 | Ck19に特異的なモノクローナル抗体およびこれを産生するハイブリドーマ、癌の検出キット、癌の検出方法および癌の転移の判定方法 |
US10301057B2 (en) | 2016-07-11 | 2019-05-28 | Calibre Closures Llc | Dispensing container with internal squeeze limiting member |
CN113061184B (zh) * | 2021-04-25 | 2022-07-01 | 福州迈新生物技术开发有限公司 | 抗ck7蛋白单克隆抗体及其细胞株、制备方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985003132A1 (en) * | 1984-01-06 | 1985-07-18 | The Regents Of The University Of California | Cytokeratin tumor markers and assays for their detection |
US4727021A (en) * | 1984-06-01 | 1988-02-23 | Sloan-Kettering Institute For Cancer Research | Human monoclonal antibodies to cytokeratin |
DE3815932A1 (de) * | 1988-01-26 | 1989-08-03 | Progen Biotechnik Gmbh | Verfahren zur identifizierung des ursprungs einer zellgewebsprobe |
DE3640412A1 (de) * | 1986-11-26 | 1988-06-09 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung einer spezifisch bindefaehigen substanz |
-
1989
- 1989-12-27 DE DE3942999A patent/DE3942999C2/de not_active Expired - Fee Related
-
1990
- 1990-12-27 DE DE59008810T patent/DE59008810D1/de not_active Expired - Fee Related
- 1990-12-27 ES ES91902191T patent/ES2070488T5/es not_active Expired - Lifetime
- 1990-12-27 EP EP91902191A patent/EP0460190B2/de not_active Expired - Lifetime
- 1990-12-27 JP JP3502417A patent/JPH082919B2/ja not_active Expired - Fee Related
- 1990-12-27 AT AT91902191T patent/ATE120550T1/de not_active IP Right Cessation
- 1990-12-27 CA CA002046888A patent/CA2046888A1/en not_active Abandoned
- 1990-12-27 DK DK91902191.5T patent/DK0460190T3/da active
- 1990-12-27 US US07/730,953 patent/US5288614A/en not_active Expired - Lifetime
- 1990-12-27 WO PCT/EP1990/002314 patent/WO1991010139A1/de active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
DE3942999C2 (de) | 1997-12-18 |
EP0460190B2 (de) | 2001-11-28 |
ES2070488T5 (es) | 2002-07-01 |
EP0460190A1 (de) | 1991-12-11 |
CA2046888A1 (en) | 1991-06-28 |
JPH082919B2 (ja) | 1996-01-17 |
US5288614A (en) | 1994-02-22 |
EP0460190B1 (de) | 1995-03-29 |
JPH04504063A (ja) | 1992-07-23 |
DK0460190T3 (da) | 1995-08-28 |
DE3942999A1 (de) | 1991-07-04 |
WO1991010139A1 (de) | 1991-07-11 |
ATE120550T1 (de) | 1995-04-15 |
DE59008810D1 (de) | 1995-05-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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