ATE522813T1 - Verfahren für den nachweis karzinomatöser epithelzellen mittels freigesetzter zytokeratine als marker für diese zellen - Google Patents
Verfahren für den nachweis karzinomatöser epithelzellen mittels freigesetzter zytokeratine als marker für diese zellenInfo
- Publication number
- ATE522813T1 ATE522813T1 AT07825055T AT07825055T ATE522813T1 AT E522813 T1 ATE522813 T1 AT E522813T1 AT 07825055 T AT07825055 T AT 07825055T AT 07825055 T AT07825055 T AT 07825055T AT E522813 T1 ATE522813 T1 AT E522813T1
- Authority
- AT
- Austria
- Prior art keywords
- cells
- marker
- released
- detecting
- cytokeratins
- Prior art date
Links
- 239000003550 marker Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 5
- 210000004027 cell Anatomy 0.000 title abstract 4
- 210000002919 epithelial cell Anatomy 0.000 title abstract 4
- 102000011782 Keratins Human genes 0.000 abstract 1
- 108010076876 Keratins Proteins 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84290206P | 2006-09-07 | 2006-09-07 | |
PCT/IB2007/002549 WO2008029251A2 (en) | 2006-09-07 | 2007-09-04 | Method for the detection of cancerous epithelial cells using released cytokeratins as markers for said cells |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE522813T1 true ATE522813T1 (de) | 2011-09-15 |
Family
ID=39027595
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT07825055T ATE522813T1 (de) | 2006-09-07 | 2007-09-04 | Verfahren für den nachweis karzinomatöser epithelzellen mittels freigesetzter zytokeratine als marker für diese zellen |
Country Status (5)
Country | Link |
---|---|
US (1) | US8524493B2 (de) |
EP (1) | EP2064552B1 (de) |
AT (1) | ATE522813T1 (de) |
ES (1) | ES2375453T3 (de) |
WO (1) | WO2008029251A2 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0815675D0 (en) | 2008-08-28 | 2008-10-08 | Mabtech Ab | Antibody secreting cell elispot |
US9535065B2 (en) | 2011-09-06 | 2017-01-03 | Becton, Dickinson And Company | Methods and compositions for cytometric detection of rare target cells in a sample |
JP6352909B2 (ja) | 2012-06-27 | 2018-07-04 | バーグ エルエルシー | 前立腺癌の診断および処置におけるマーカーの使用 |
US10539566B2 (en) | 2014-12-08 | 2020-01-21 | Berg Llc | Use of markers including filamin A in the diagnosis and treatment of prostate cancer |
LU500787B1 (en) | 2021-10-26 | 2023-04-27 | Univ Hamburg Eppendorf Uke | Isolation and detection of cdcp1 positive circulating tumor cells |
LU501430B1 (en) | 2022-02-09 | 2023-08-09 | Univ Hamburg Eppendorf Uke | Enrichment, detection and characterization of circulating tumor cells with susd2 and enpp1 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985003132A1 (en) | 1984-01-06 | 1985-07-18 | The Regents Of The University Of California | Cytokeratin tumor markers and assays for their detection |
DE3942999C2 (de) * | 1989-12-27 | 1997-12-18 | Progen Biotechnik Gmbh | Verfahren zum Nachweis von malignen Erkrankungen |
EP2230320B1 (de) * | 2000-03-27 | 2015-07-01 | Thomas Jefferson University | Zusammensetzung zur Behandlung und Visualisierung von Magen- und Speiseröhren-Krebszellen |
ATE331958T1 (de) | 2002-03-13 | 2006-07-15 | Biomerieux Sa | Verfahren zum nachweis und zur quantifizierung von -aus soliden tumoren abstammenden- zirkulierenden tumorzellen |
CA2498783A1 (en) * | 2002-09-12 | 2004-03-25 | Yissum Research Development Company Of The Hebrew University Of Jerusale M | Method for detection of micro-metastasis |
-
2007
- 2007-09-04 US US12/439,744 patent/US8524493B2/en active Active
- 2007-09-04 EP EP07825055A patent/EP2064552B1/de active Active
- 2007-09-04 AT AT07825055T patent/ATE522813T1/de active
- 2007-09-04 WO PCT/IB2007/002549 patent/WO2008029251A2/en active Application Filing
- 2007-09-04 ES ES07825055T patent/ES2375453T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
US8524493B2 (en) | 2013-09-03 |
WO2008029251A3 (en) | 2008-05-22 |
WO2008029251A2 (en) | 2008-03-13 |
ES2375453T3 (es) | 2012-03-01 |
EP2064552A2 (de) | 2009-06-03 |
EP2064552B1 (de) | 2011-08-31 |
US20100184083A1 (en) | 2010-07-22 |
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