ES2061689T3 - Produccion de derivados de 2,3'-anhidro-2'-desoxiuridina. - Google Patents

Produccion de derivados de 2,3'-anhidro-2'-desoxiuridina.

Info

Publication number
ES2061689T3
ES2061689T3 ES88310662T ES88310662T ES2061689T3 ES 2061689 T3 ES2061689 T3 ES 2061689T3 ES 88310662 T ES88310662 T ES 88310662T ES 88310662 T ES88310662 T ES 88310662T ES 2061689 T3 ES2061689 T3 ES 2061689T3
Authority
ES
Spain
Prior art keywords
production
anhydro
desoxiuridine
derivatives
deoxyuridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88310662T
Other languages
English (en)
Inventor
Colin Bernard Reese
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scotia Holdings PLC
Original Assignee
Scotia Holdings PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scotia Holdings PLC filed Critical Scotia Holdings PLC
Application granted granted Critical
Publication of ES2061689T3 publication Critical patent/ES2061689T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

UN PROCESO PARA LA PRODUCCION DE UN DERIVADO 5 - SUSTITUIDO DE UNA 2,3''-ANHIDRO - 2''- DESOXIURIDINA PREFERIBLEMENTE CORRESPONDIENDO A LA FORMULA(I),, DONDE R''ES H, ALQUILO, ARILO, HALOGENO O CF3, CARACTERIZADO PORQUE COMPRENDE EL CALCULAMIENTO DE UN DERIVADO 5 - SUSTITUIDO DE UNA 2''- DESOXIURIDINA PREFERIBLEMENTE CORRESPONDIENTE A LA FORMULS(I), DONDE R''ES COMO SE DEFINE MAS ARRIBA; EN LA PRESENCIA DE UN AGENTE DE TRANSFERENCIA DE SULFITO Y PREFERIBLEMENTE UN DISOLVENTE. ESTE PROCESO MEJORA LA PRODUCCION DE INTERMEDIOS VALIDOS Y POR TANTO FACILITA Y REDUCE EL COSTE DE PRODUCCION DE COMPUESTOS INTERESANTES FARMACOLOGICAMENTE.
ES88310662T 1987-11-13 1988-11-11 Produccion de derivados de 2,3'-anhidro-2'-desoxiuridina. Expired - Lifetime ES2061689T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878726585A GB8726585D0 (en) 1987-11-13 1987-11-13 Chemical process

Publications (1)

Publication Number Publication Date
ES2061689T3 true ES2061689T3 (es) 1994-12-16

Family

ID=10626889

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88310662T Expired - Lifetime ES2061689T3 (es) 1987-11-13 1988-11-11 Produccion de derivados de 2,3'-anhidro-2'-desoxiuridina.

Country Status (13)

Country Link
US (1) US4937329A (es)
EP (1) EP0317207B1 (es)
JP (1) JP2636024B2 (es)
KR (1) KR970003129B1 (es)
AT (1) ATE101160T1 (es)
AU (1) AU602615B2 (es)
CA (1) CA1316918C (es)
DE (1) DE3887643T2 (es)
ES (1) ES2061689T3 (es)
GB (1) GB8726585D0 (es)
IE (1) IE63216B1 (es)
NZ (1) NZ226872A (es)
ZA (1) ZA888377B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050131224A1 (en) * 2003-12-15 2005-06-16 Cti Pet Systems, Inc. Method for preparing radiolabeled thymidine
US7160537B2 (en) * 2003-12-15 2007-01-09 Siemens Medical Solutions Usa, Inc. Method for preparing radiolabeled thymidine having low chromophoric byproducts

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD77233A (es) *
JPS5914040B2 (ja) * 1976-04-05 1984-04-02 ヤマサ醤油株式会社 Ｏ↑２，３′−サイクロピリミジンヌクレオシド類の製造法
FR2640267B2 (fr) * 1988-01-19 1992-02-14 Univ Paris Curie Procede de synthese de l'azido-3(prime)-desoxy-3(prime)-thymidine et analogues

Also Published As

Publication number Publication date
US4937329A (en) 1990-06-26
AU2505488A (en) 1989-05-18
KR900007864A (ko) 1990-06-02
DE3887643T2 (de) 1994-06-16
DE3887643D1 (de) 1994-03-17
AU602615B2 (en) 1990-10-18
IE63216B1 (en) 1995-04-05
EP0317207A3 (en) 1990-11-28
EP0317207B1 (en) 1994-02-02
JPH01258696A (ja) 1989-10-16
IE883398L (en) 1989-05-13
EP0317207A2 (en) 1989-05-24
GB8726585D0 (en) 1987-12-16
NZ226872A (en) 1989-10-27
JP2636024B2 (ja) 1997-07-30
KR970003129B1 (ko) 1997-03-14
CA1316918C (en) 1993-04-27
ATE101160T1 (de) 1994-02-15
ZA888377B (en) 1989-11-29

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