ES2052878T3 - Nuevos derivados de azucares, metodo para su produccion y aplicacion. - Google Patents

Nuevos derivados de azucares, metodo para su produccion y aplicacion.

Info

Publication number
ES2052878T3
ES2052878T3 ES89123301T ES89123301T ES2052878T3 ES 2052878 T3 ES2052878 T3 ES 2052878T3 ES 89123301 T ES89123301 T ES 89123301T ES 89123301 T ES89123301 T ES 89123301T ES 2052878 T3 ES2052878 T3 ES 2052878T3
Authority
ES
Spain
Prior art keywords
hydrogen atom
alkyl
alkyl group
formula
sugar derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89123301T
Other languages
English (en)
Inventor
Ernst Nitsch
Bernhard Lotz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laevosan GmbH and Co KG
Original Assignee
Laevosan GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laevosan GmbH and Co KG filed Critical Laevosan GmbH and Co KG
Application granted granted Critical
Publication of ES2052878T3 publication Critical patent/ES2052878T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02Monosaccharides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

DERIVADOS DEL AZUCAR DE LAS FORMULAS GENERALES I Y II EN LA QUE R SUB 1 SIGNIFICA UN ATOMO DE HIDROGENO O UN GRUPO ALCOHILO CON 1 A 7 ATOMOS DE CARBONO, R SUB 2 Y R SUB 3 SIGNIFICAN UN ATOMO DE HIDROGENO O, CUANDO R SUB 1 SIGNIFICA UN GRUPO ALCOHILO, SIGNIFICAN TAMBIEN UN GRUPO ACILO R SUB 4 CO.R SIGNIFICA UN ATOMO DE HIDROGENO O UN GRUPO ACILO R SUB 5 CO,Y R SUB 4 Y R SU B5 SIGNIFICAN UN GRUPO ALCOHILO CON 1 A 7 ATOMOS DE CARBONO, POSEEN UNA ACTIVIDAD CITOTOXICA ANTIPROLIFERATIVA EXCELENTE CON UNA TOXICIDAD MUY BAJA. LOS COMPUESTOS DE LAS FORMULAS I Y II SE PUEDEN FABRICAR TRATANDO DI Y OLIGOSACARIDOS ALFA Y BETA-1,4-ENLAZADOS, QUE CONTIENEN EN SU EXTREMO REDUCTOR UNA MOLECULA DE GLUCOSA, DE FRUCTOSA O DE MANNOSA, CON BASES INORGANICAS U ORGANICAS, AISLANDO DE MANERA CONOCIDA DE LA MEZCLA DE REACCION OBTENIDA LA 3 LA FORMULA I, EN LA QUE R SUB 1, R SUB 2 Y R SUB 3 SIGNIFICAN UN ATOMO DE HIDROGENO Y, SE DESEA, TRANSFORMANDO EL 3-DGP DE MANERA CONOCIDA EN SU GLICOSIDO (I, R SUB 1 = ALCOHILO,R SUB 2, R SUB 3 = H), DIGLICOSIDO (I, R SUB 1 = ALCOHILO, R SUB 2, R SUB 3 = R SUB 4 CO), DIANHIDRIDO (II, R = H) O DIACILDIANHIDRIDO (II, R = R SUB 5 CO).
ES89123301T 1989-12-15 1989-12-15 Nuevos derivados de azucares, metodo para su produccion y aplicacion. Expired - Lifetime ES2052878T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP89123301A EP0432309B1 (de) 1989-12-15 1989-12-15 Neue Zuckerderivate, Verfahren zu ihrer Herstellung und ihre Verwendung

Publications (1)

Publication Number Publication Date
ES2052878T3 true ES2052878T3 (es) 1994-07-16

Family

ID=8202239

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89123301T Expired - Lifetime ES2052878T3 (es) 1989-12-15 1989-12-15 Nuevos derivados de azucares, metodo para su produccion y aplicacion.

Country Status (7)

Country Link
EP (1) EP0432309B1 (es)
AT (1) ATE105294T1 (es)
DE (1) DE58907621D1 (es)
DK (1) DK170171B1 (es)
ES (1) ES2052878T3 (es)
FI (1) FI906181A (es)
NO (1) NO175206C (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2929509B1 (fr) * 2008-04-02 2011-01-21 Lvmh Rech L'utilisation de glycosides d'alkyle ou de melanges de glycosides d'alkyle en tant qu'agents destines a inhiber la croissance microbienne, et compositions contenant lesdits glycosides d'alkyle.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2609397B1 (fr) * 1988-02-23 1991-12-13 Serobiologiques Lab Sa Utilisation d'une substance ou composition de nature glucidique comme principe actif d'une composition dermatologique et/ou cosmetologique et/ou pharmaceutique et/ou stimulante cellulaire, et composition contenant une telle substance ou composition de nature glucidique

Also Published As

Publication number Publication date
NO905417D0 (no) 1990-12-14
EP0432309A1 (de) 1991-06-19
EP0432309B1 (de) 1994-05-04
FI906181A (fi) 1991-06-16
FI906181A0 (fi) 1990-12-14
DK295490A (da) 1991-06-16
DK295490D0 (da) 1990-12-12
NO175206B (es) 1994-06-06
ATE105294T1 (de) 1994-05-15
DK170171B1 (da) 1995-06-06
NO905417L (no) 1991-06-17
NO175206C (no) 1994-09-14
DE58907621D1 (de) 1994-06-09

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