ES2051704T3 - Procedimiento mejorado para preparar antra(1,9-cd)pirazol-6(2h)-onas substituidas. - Google Patents

Procedimiento mejorado para preparar antra(1,9-cd)pirazol-6(2h)-onas substituidas.

Info

Publication number
ES2051704T3
ES2051704T3 ES87106486T ES87106486T ES2051704T3 ES 2051704 T3 ES2051704 T3 ES 2051704T3 ES 87106486 T ES87106486 T ES 87106486T ES 87106486 T ES87106486 T ES 87106486T ES 2051704 T3 ES2051704 T3 ES 2051704T3
Authority
ES
Spain
Prior art keywords
antra
pirazol
waves
substituted
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87106486T
Other languages
English (en)
Inventor
Vladimir Genukh Beylin
Howard Daniel Hollis Showalter
Om Prakash Goel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Application granted granted Critical
Publication of ES2051704T3 publication Critical patent/ES2051704T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

SE DESCRIBE UN PROCEDIMIENTO MEJORADO PARA LA OBTENCION DE ANTRA(1,9-CD)-PIRAZOL-6(2H)-ONAS A PARTIR DE 1,4-DICLORO-9,10-ANTRACENDIONAS 5,8 DISUSTITUIDAS. EL PROCEDIMIENTO OBTIENE RENDIMIENTOS MAS ALTOS MEDIANTE EL EMPLEO DE UNA NUEVA COOMBINACION DE GRUPOS PROTECTORES DE LOS COMPUESTOS QUE PERMITE UNA RESOLUCION CROMATOGRAFICA MAS FACIL Y MAS LIMPIA. LOS COMPUESTOS OBTENIDOS PRESENTAN ACTIVIDAD ANTIBACTERIANA, ANTIFUNGICA, ANTILEUCEMICA Y ANTITUMORAL.
ES87106486T 1986-05-05 1987-05-05 Procedimiento mejorado para preparar antra(1,9-cd)pirazol-6(2h)-onas substituidas. Expired - Lifetime ES2051704T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/859,673 US4672129A (en) 1986-05-05 1986-05-05 Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones

Publications (1)

Publication Number Publication Date
ES2051704T3 true ES2051704T3 (es) 1994-07-01

Family

ID=25331470

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87106486T Expired - Lifetime ES2051704T3 (es) 1986-05-05 1987-05-05 Procedimiento mejorado para preparar antra(1,9-cd)pirazol-6(2h)-onas substituidas.

Country Status (20)

Country Link
US (1) US4672129A (es)
EP (1) EP0244819B1 (es)
JP (1) JPH0826004B2 (es)
KR (1) KR950000295B1 (es)
AT (1) ATE79375T1 (es)
AU (1) AU596654B2 (es)
CA (1) CA1274513A (es)
DE (1) DE3781015T2 (es)
DK (1) DK164858C (es)
ES (1) ES2051704T3 (es)
FI (1) FI91963C (es)
GR (1) GR3005543T3 (es)
HU (1) HUT44241A (es)
IE (1) IE60078B1 (es)
IL (1) IL82247A0 (es)
NO (1) NO174046C (es)
NZ (1) NZ220133A (es)
PH (1) PH24061A (es)
PT (1) PT84815B (es)
ZA (1) ZA872726B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE192177T1 (de) * 1993-02-19 2000-05-15 Cytec Tech Corp Härtbare verbundwerkstoffe
US5393886A (en) * 1993-05-05 1995-02-28 The Du Pont Merck Pharmaceutical Company Intermediates for the synthesis of anthrapyrazolone anticancer agents
WO2000021565A1 (en) 1998-10-13 2000-04-20 Du Pont Pharmaceuticals Company Selective eradication of virally-infected cells by combined use of a cytotoxic agent and an antiviral agent
US9376406B2 (en) 2011-03-03 2016-06-28 Indiana University Research And Technology Corporation uPAR-uPA interaction inhibitors and methods for treating cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH439331A (de) * 1964-03-13 1967-07-15 Bayer Ag Verfahren zur Herstellung von hydroxygruppenhaltigen 1,4-Dichloranthrachinonen
US4556654A (en) * 1983-06-28 1985-12-03 Warner-Lambert Company Antimicrobial substituted anthra[1,9-cd]pyrazol-6(2H)-ones
IL69211A (en) * 1982-07-23 1987-01-30 Warner Lambert Co Substituted anthra(1,9-cd)pyrazol-6(2h)-ones,their preparation and pharmaceutical compositions containing them
US4608439A (en) * 1985-04-26 1986-08-26 Warner-Lambert Company Process for preparing substituted anthra[1,9-cd]pyrazol-6(2H)-ones

Also Published As

Publication number Publication date
FI91963C (fi) 1994-09-12
US4672129A (en) 1987-06-09
CA1274513A (en) 1990-09-25
AU596654B2 (en) 1990-05-10
IE870916L (en) 1987-11-05
DE3781015T2 (de) 1992-12-17
FI871945L (fi) 1987-11-06
DK164858C (da) 1993-01-11
JPH0826004B2 (ja) 1996-03-13
ATE79375T1 (de) 1992-08-15
IE60078B1 (en) 1994-06-01
NZ220133A (en) 1989-05-29
ZA872726B (en) 1988-11-30
DK222987A (da) 1987-11-06
KR870011102A (ko) 1987-12-21
DK164858B (da) 1992-08-31
FI91963B (fi) 1994-05-31
DE3781015D1 (de) 1992-09-17
KR950000295B1 (ko) 1995-01-13
FI871945A0 (fi) 1987-05-04
HUT44241A (en) 1988-02-29
DK222987D0 (da) 1987-05-01
NO174046B (no) 1993-11-29
AU7156187A (en) 1987-11-12
NO871842D0 (no) 1987-05-04
IL82247A0 (en) 1987-10-30
EP0244819B1 (en) 1992-08-12
PT84815A (en) 1987-06-01
NO174046C (no) 1994-03-09
PT84815B (pt) 1989-12-29
NO871842L (no) 1987-11-06
EP0244819A3 (en) 1989-04-26
GR3005543T3 (es) 1993-06-07
EP0244819A2 (en) 1987-11-11
PH24061A (en) 1990-03-05
JPS62263160A (ja) 1987-11-16

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