ES2050668T3 - Composiciones que mejoran la permeabilidad de la piel con el uso de monolaurato de glicerol. - Google Patents

Composiciones que mejoran la permeabilidad de la piel con el uso de monolaurato de glicerol.

Info

Publication number
ES2050668T3
ES2050668T3 ES87310772T ES87310772T ES2050668T3 ES 2050668 T3 ES2050668 T3 ES 2050668T3 ES 87310772 T ES87310772 T ES 87310772T ES 87310772 T ES87310772 T ES 87310772T ES 2050668 T3 ES2050668 T3 ES 2050668T3
Authority
ES
Spain
Prior art keywords
skin
permeability
compositions
improve
glycerol monolaurate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87310772T
Other languages
English (en)
Inventor
Yu-Ling Cheng
Diane E Nedberge
Edna Sugihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21793396&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2050668(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2050668T3 publication Critical patent/ES2050668T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE DESCRIBE UN METODO PARA AUMENTAR EL FLUJE TRANSDERMICO DE UN FARMACO LIBERABLE POR VIA TRANSDERMICA A TRAVES DE PIEL INTACTA, EN EL QUE EL MEDICAMENTO SE DESCARGA SIMULTANEAMENTE CON MONOLAURATO DE GLICERINA. EN UNA DE LAS REIVINDICACIONES LOS SISTEMAS TERAPEUTICOS PARA LIBERACION DEL MEDICAMENTO Y DEL MONOLAURATO DE GLICEROL EMPLEAN UNA MATRIZ QUE CONTIENE EL MEDICAMENTO A UNA CONCENTRACION MAYOR DE LA DE SATURACION
ES87310772T 1987-02-26 1987-12-08 Composiciones que mejoran la permeabilidad de la piel con el uso de monolaurato de glicerol. Expired - Lifetime ES2050668T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/019,470 US4746515A (en) 1987-02-26 1987-02-26 Skin permeation enhancer compositions using glycerol monolaurate

Publications (1)

Publication Number Publication Date
ES2050668T3 true ES2050668T3 (es) 1994-06-01

Family

ID=21793396

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87310772T Expired - Lifetime ES2050668T3 (es) 1987-02-26 1987-12-08 Composiciones que mejoran la permeabilidad de la piel con el uso de monolaurato de glicerol.

Country Status (6)

Country Link
US (1) US4746515A (es)
EP (1) EP0279986B1 (es)
JP (1) JP2650701B2 (es)
CA (1) CA1316106C (es)
DE (1) DE3789617T2 (es)
ES (1) ES2050668T3 (es)

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Also Published As

Publication number Publication date
CA1316106C (en) 1993-04-13
US4746515A (en) 1988-05-24
DE3789617T2 (de) 1994-07-21
JP2650701B2 (ja) 1997-09-03
DE3789617D1 (de) 1994-05-19
EP0279986B1 (en) 1994-04-13
EP0279986A1 (en) 1988-08-31
JPS63227520A (ja) 1988-09-21

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