ES2039346T3 - Esteres de acidos beta-carbolin-3-carboxilicos sustituidos en posicion 5 o 6. - Google Patents

Esteres de acidos beta-carbolin-3-carboxilicos sustituidos en posicion 5 o 6.

Info

Publication number
ES2039346T3
ES2039346T3 ES198686115006T ES86115006T ES2039346T3 ES 2039346 T3 ES2039346 T3 ES 2039346T3 ES 198686115006 T ES198686115006 T ES 198686115006T ES 86115006 T ES86115006 T ES 86115006T ES 2039346 T3 ES2039346 T3 ES 2039346T3
Authority
ES
Spain
Prior art keywords
acid esters
carbolin
carboxyl acid
substituted
substituted beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198686115006T
Other languages
English (en)
Inventor
Tage Dr. Honore
Helmut Dr. Biere
Andreas Dr. Huth
Dieter Dr. Rahtz
Ralph Dr. Schmiechen
Dieter Dr. Seidelmann.
Wolfgang Dr. Kehr
Herbert Hans Dr. Schneider
Mogens Dr. Engelstoft
Bondo John Dr. Hansen
Frank Dr. Watjen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2039346T3 publication Critical patent/ES2039346T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Fats And Perfumes (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Esteres de ácidos Beta-carbolin-3-carboxílicos, sustituidos en posiciones 5 ó 6, de fórmula general I en donde R1 significa hidrógeno, nitrilo, halógeno, alquilo C1-4 o alcoxi C1-4; y R3 es un grupo alquilo C3-6 ramificado, que eventualmente esta sustituido con halógeno, o un grupo cicloalquilo C3-6, que eventualmente está sustituido con metilo; y R1 puede presentarse una ó múltiples veces. (Reserva del art. 167.2 CPE).
ES198686115006T 1986-03-20 1986-10-29 Esteres de acidos beta-carbolin-3-carboxilicos sustituidos en posicion 5 o 6. Expired - Lifetime ES2039346T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863609699 DE3609699A1 (de) 1986-03-20 1986-03-20 5- oder 6-substituierte-(beta)-carbolin-3-carbonsaeureester

Publications (1)

Publication Number Publication Date
ES2039346T3 true ES2039346T3 (es) 1993-10-01

Family

ID=6297016

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198686115006T Expired - Lifetime ES2039346T3 (es) 1986-03-20 1986-10-29 Esteres de acidos beta-carbolin-3-carboxilicos sustituidos en posicion 5 o 6.

Country Status (24)

Country Link
US (2) US5414002A (es)
EP (1) EP0239667B1 (es)
JP (1) JPH0670053B2 (es)
AT (1) ATE63119T1 (es)
AU (1) AU596385B2 (es)
CA (1) CA1332837C (es)
CS (2) CS277411B6 (es)
DD (1) DD260068A5 (es)
DE (2) DE3609699A1 (es)
DK (1) DK168953B1 (es)
ES (1) ES2039346T3 (es)
FI (2) FI864498A0 (es)
GR (1) GR3002085T3 (es)
HU (1) HU195218B (es)
IE (1) IE59344B1 (es)
IL (1) IL80667A (es)
MX (1) MX9203701A (es)
NO (2) NO864362D0 (es)
NZ (1) NZ218482A (es)
PH (1) PH25100A (es)
PT (1) PT83763B (es)
RU (2) RU1771475C (es)
UA (2) UA13475A (es)
ZA (1) ZA872072B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4122722A1 (de) * 1991-07-06 1993-01-07 Schering Ag Verfahren zur herstellung von indol-derivaten
DE19502753A1 (de) * 1995-01-23 1996-07-25 Schering Ag Neue 9H-Pyrido[3,4-b]indol-Derivate
DE10136842A1 (de) * 2001-07-23 2003-02-13 Schering Ag GABA¶A¶-Rezeptor-Modulatoren mit NMDA-antagonistischer Aktivität
US20030045541A1 (en) * 2001-07-23 2003-03-06 Christopher Bruckner GABA-Receptor modulators with NMDA-Antagonistic activity

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ194747A (en) * 1979-08-29 1988-11-29 Schering Ag 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3240511A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinderivaten
DE3322895A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ss-carboline, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel (s)
DE3335323A1 (de) * 1983-09-27 1985-04-04 Schering AG, 1000 Berlin und 4709 Bergkamen Substituierte ss-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DK240184D0 (da) * 1984-05-15 1984-05-15 Ferrosan As Beta-carboline-3-carboxylic acid derivatives and method of preparing the same
DK704488D0 (da) * 1988-12-19 1988-12-19 Novo Industri As Nye n-substituerede azaheterocykliske carboxylsyrer
DE3504045A1 (de) * 1985-02-04 1986-08-07 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinen durch dehydrierung
DE3540653A1 (de) * 1985-11-13 1987-05-14 Schering Ag Neue 3-oxadiazol- und 3-carbonsaeure-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3545776A1 (de) * 1985-12-20 1987-06-25 Schering Ag 5-aminoalkyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
PT83763B (pt) 1989-07-31
DE3679059D1 (de) 1991-06-06
NO163737B (no) 1990-04-02
DE3609699A1 (de) 1987-09-24
FI83321C (fi) 1991-06-25
CS938686A3 (en) 1992-11-18
EP0239667B1 (de) 1991-05-02
IL80667A0 (en) 1987-02-27
DK168953B1 (da) 1994-07-18
NO865121L (no) 1987-09-21
US5700808A (en) 1997-12-23
JPS62221684A (ja) 1987-09-29
NZ218482A (en) 1990-01-29
NO865121D0 (no) 1986-12-17
UA13475A (uk) 1997-04-25
NO864362D0 (no) 1986-10-31
IL80667A (en) 1991-04-15
RU1771475C (ru) 1992-10-23
ATE63119T1 (de) 1991-05-15
AU596385B2 (en) 1990-05-03
UA26390A (uk) 1999-08-30
PH25100A (en) 1991-02-19
DD260068A5 (de) 1988-09-14
FI83321B (fi) 1991-03-15
CS277498B6 (en) 1993-02-17
US5414002A (en) 1995-05-09
RU2034845C1 (ru) 1995-05-10
CS277411B6 (en) 1993-03-17
CA1332837C (en) 1994-11-01
EP0239667A1 (de) 1987-10-07
NO163737C (no) 1990-07-11
HU195218B (en) 1988-04-28
DK536386D0 (da) 1986-11-10
ZA872072B (en) 1987-09-14
GR3002085T3 (en) 1992-12-30
FI865058A (fi) 1987-09-21
HUT41787A (en) 1987-05-28
IE59344B1 (en) 1994-02-09
IE863094L (en) 1987-09-20
JPH0670053B2 (ja) 1994-09-07
CS363490A3 (en) 1992-11-18
MX9203701A (es) 1992-09-01
PT83763A (de) 1986-12-01
FI865058A0 (fi) 1986-12-11
DK536386A (da) 1987-09-21
AU6516886A (en) 1987-09-24
FI864498A0 (fi) 1986-11-05

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