ES2032553T3 - Dispositivo de cesion transdermica de farmacos con dos mejoradores de permeacion. - Google Patents

Dispositivo de cesion transdermica de farmacos con dos mejoradores de permeacion.

Info

Publication number
ES2032553T3
ES2032553T3 ES198888302920T ES88302920T ES2032553T3 ES 2032553 T3 ES2032553 T3 ES 2032553T3 ES 198888302920 T ES198888302920 T ES 198888302920T ES 88302920 T ES88302920 T ES 88302920T ES 2032553 T3 ES2032553 T3 ES 2032553T3
Authority
ES
Spain
Prior art keywords
transdermic
drugs
transfer
drug
enhancers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888302920T
Other languages
English (en)
Inventor
Harold F. Sanders
David J. Enscore
Yu-Ling Cheng
Shari B. Libicki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2032553T3 publication Critical patent/ES2032553T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L29/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBE UNA FORMA DE DOSIS QUE COADMINISTRA UN MEDICAMENTO Y DOS INTENSIFICADORES DE ABSORCION PERCUTANEA A UN AREA DEFINIDA DE LA PIEL. LA FORMA DE DOSIS COMPRENDE UN CUERPO QUE CONTIENE PROVISIONES DE MEDICAMENTO E INTENSIFICADORES Y TIENE UNA SUPERFICIE BASAL QUE PONE EN CONTACTO EL AREA DE LA PIEL Y TRANSMITE EL MEDICAMENTO Y LOS INTENSIFICADORES AL AREA DE ABSORCION.
ES198888302920T 1987-08-24 1988-03-31 Dispositivo de cesion transdermica de farmacos con dos mejoradores de permeacion. Expired - Lifetime ES2032553T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/088,767 US4764379A (en) 1987-08-24 1987-08-24 Transdermal drug delivery device with dual permeation enhancers

Publications (1)

Publication Number Publication Date
ES2032553T3 true ES2032553T3 (es) 1993-02-16

Family

ID=22213333

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888302920T Expired - Lifetime ES2032553T3 (es) 1987-08-24 1988-03-31 Dispositivo de cesion transdermica de farmacos con dos mejoradores de permeacion.

Country Status (10)

Country Link
US (1) US4764379A (es)
EP (1) EP0305026B1 (es)
JP (1) JP2650713B2 (es)
KR (1) KR960014996B1 (es)
AT (1) ATE77250T1 (es)
AU (1) AU600210B2 (es)
CA (1) CA1313352C (es)
DE (1) DE3872109T2 (es)
ES (1) ES2032553T3 (es)
GR (1) GR3004941T3 (es)

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US4863970A (en) * 1986-11-14 1989-09-05 Theratech, Inc. Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
US4906463A (en) * 1986-12-22 1990-03-06 Cygnus Research Corporation Transdermal drug-delivery composition
US5112804A (en) * 1987-04-01 1992-05-12 Temple University Of The Commonwealth System Of Higher Education Pharmaceutical composition and method of intranasal administration
CH674618A5 (es) * 1987-04-02 1990-06-29 Ciba Geigy Ag
US4820720A (en) * 1987-08-24 1989-04-11 Alza Corporation Transdermal drug composition with dual permeation enhancers
US4849224A (en) * 1987-11-12 1989-07-18 Theratech Inc. Device for administering an active agent to the skin or mucosa
US4983395A (en) * 1987-11-12 1991-01-08 Theratech Inc. Device for administering an active agent to the skin or mucosa
US4906475A (en) 1988-02-16 1990-03-06 Paco Pharmaceutical Services Estradiol transdermal delivery system
US5641504A (en) * 1988-06-09 1997-06-24 Alza Corporation Skin permeation enhancer compositions using glycerol monolinoleate
PT90784A (pt) * 1988-06-09 1989-12-29 Alza Corp Processo para a preparacao de uma composicao de materiais para aplicacao sobre uma superficie corporal ou membral
US5028434A (en) * 1988-07-21 1991-07-02 Alza Corporation Method for administering nilvadipine for treating cardiovascular symptoms
US4902514A (en) * 1988-07-21 1990-02-20 Alza Corporation Dosage form for administering nilvadipine for treating cardiovascular symptoms
AU628419B2 (en) * 1988-10-26 1992-09-17 Hisamitsu Pharmaceutical Co. Ltd. Interface for electric endermism
US5008110A (en) * 1988-11-10 1991-04-16 The Procter & Gamble Company Storage-stable transdermal patch
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US5059426A (en) * 1989-03-22 1991-10-22 Cygnus Therapeutic Systems Skin permeation enhancer compositions, and methods and transdermal systems associated therewith
US5059603A (en) * 1989-06-12 1991-10-22 Centuries Laboratories, Inc. Method and composition for treating impotence
US5229129A (en) * 1989-07-12 1993-07-20 Cygnus Therapeutic Systems Transdermal administration of lisuride
US5252335A (en) * 1989-07-12 1993-10-12 Cygnus Therapeutic Systems Transdermal administration of lisuride
US4956171A (en) * 1989-07-21 1990-09-11 Paco Pharmaceutical Services, Inc. Transdermal drug delivery using a dual permeation enhancer and method of performing the same
JPH03123727A (ja) * 1989-10-04 1991-05-27 Nitto Denko Corp 経皮吸収製剤
ES2095929T3 (es) * 1989-10-23 1997-03-01 Theratech Inc Dispositivo iontoforetico que emplea un regulador del regimen.
US5246949A (en) * 1989-12-06 1993-09-21 Sansho Co., Ltd. Preparation for endermism containing dopamine derivatives
US5057500A (en) * 1990-02-12 1991-10-15 Dermatologic Research Corporation Treatment of pruritis with esters and amides
FR2662361A1 (fr) * 1990-05-23 1991-11-29 Schlee Serge Pansement de type humide ssj1.
PT100502A (pt) * 1991-05-20 1993-08-31 Alza Corp Composicoes farmaceuticas para aumentar a capacidade de permeacao na pele utilizando monolinoleato de glicerol
US5507810A (en) * 1991-10-07 1996-04-16 Osteotech, Inc. Processing of fibrous connective tissue
US5352456A (en) * 1991-10-10 1994-10-04 Cygnus Therapeutic Systems Device for administering drug transdermally which provides an initial pulse of drug
US5229130A (en) * 1991-12-20 1993-07-20 Cygnus Therapeutics Systems Vegetable oil-based skin permeation enhancer compositions, and associated methods and systems
DE4429667C2 (de) * 1994-08-20 1996-07-11 Lohmann Therapie Syst Lts Estradiol-TTS mit wasserbindenden Zusätzen und Verfahren zu seiner Herstellung
US5505958A (en) * 1994-10-31 1996-04-09 Algos Pharmaceutical Corporation Transdermal drug delivery device and method for its manufacture
US5785991A (en) * 1995-06-07 1998-07-28 Alza Corporation Skin permeation enhancer compositions comprising glycerol monolaurate and lauryl acetate
US6572879B1 (en) 1995-06-07 2003-06-03 Alza Corporation Formulations for transdermal delivery of pergolide
DE69718037T2 (de) * 1996-10-24 2003-07-10 Alza Corp Penetrationsfördernde substanzen für die transdermale verabreichung von wirkstoffen, vorrichtungen und verfahren zur herstellung
WO1999032153A1 (en) 1997-12-22 1999-07-01 Alza Corporation Monoglyceride and ethyl palmitate permeation enhancer compositions
US6269820B1 (en) 1998-02-26 2001-08-07 Xomed Surgical Products, Inc. Method of controlling post-operative leakage associated with tumescent liposuction
EP1094781B1 (en) * 1998-07-07 2008-07-02 Transdermal Technologies Inc. Compositions for rapid and non-irritating transdermal delivery of pharmaceutically active agents and methods for formulating such compositions and delivery thereof
US6699497B1 (en) 1998-07-24 2004-03-02 Alza Corporation Formulations for the transdermal administration of fenoldopam
US20060212025A1 (en) * 1998-11-30 2006-09-21 Light Bioscience, Llc Method and apparatus for acne treatment
US9192780B2 (en) 1998-11-30 2015-11-24 L'oreal Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders
US6283956B1 (en) * 1998-11-30 2001-09-04 David H. McDaniels Reduction, elimination, or stimulation of hair growth
US6887260B1 (en) 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
US6936044B2 (en) * 1998-11-30 2005-08-30 Light Bioscience, Llc Method and apparatus for the stimulation of hair growth
US7179483B2 (en) 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
US20060121103A1 (en) * 2000-05-11 2006-06-08 Kenneth Kirby Transdermal delivery system
JP2002145434A (ja) * 2000-11-10 2002-05-22 Okamura Corp ベルトコンベヤ
AU2002319653A1 (en) * 2001-07-20 2003-03-03 Samir Mitragotri Method for oral drug delivery
US7309359B2 (en) 2003-08-21 2007-12-18 Warsaw Orthopedic, Inc. Allogenic/xenogenic implants and methods for augmenting or repairing intervertebral discs
US7887593B2 (en) 2002-09-18 2011-02-15 Warsaw Orthopedic, Inc. Method of implanting natural tissue within the vertebral disc nucleus space using a drawstring
JP2006522660A (ja) * 2003-04-10 2006-10-05 ライト バイオサイエンス，エルエルシー 細胞増殖及び遺伝子発現を調節するためのフォトモジュレーション方法及び装置
US20040258742A1 (en) * 2003-04-11 2004-12-23 Van Osdol William Woodson Transdermal administration of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methyl guanidines
US20050149150A1 (en) * 2003-07-31 2005-07-07 Light Bioscience L.L.C. System and method for the photodynamic treatment of burns, wounds, and related skin disorders
US7105263B2 (en) * 2003-12-30 2006-09-12 Samsung Electronics Company Dry toner comprising encapsulated pigment, methods and uses
US20060008432A1 (en) * 2004-07-07 2006-01-12 Sebastiano Scarampi Gilsonite derived pharmaceutical delivery compositions and methods: nail applications
US9155713B2 (en) * 2011-03-03 2015-10-13 Mark Stephen Saia Method and apparatus for alcohol administration and therapeutic treatments using same
US20120225112A1 (en) * 2011-03-03 2012-09-06 Mark Stephen Saia Method and Apparatus for Alcohol Administration
WO2023081539A1 (en) 2021-11-08 2023-05-11 Weiyong Li Transdermal drug delivery system for delivering a drug to a patient

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Also Published As

Publication number Publication date
US4764379A (en) 1988-08-16
JPS6468314A (en) 1989-03-14
ATE77250T1 (de) 1992-07-15
EP0305026B1 (en) 1992-06-17
KR890003413A (ko) 1989-04-14
EP0305026A2 (en) 1989-03-01
DE3872109T2 (de) 1992-12-03
GR3004941T3 (es) 1993-04-28
AU1379988A (en) 1989-03-02
JP2650713B2 (ja) 1997-09-03
EP0305026A3 (en) 1990-02-14
AU600210B2 (en) 1990-08-02
KR960014996B1 (ko) 1996-10-23
DE3872109D1 (de) 1992-07-23
CA1313352C (en) 1993-02-02

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