ES2032427T3 - Procedimiento para producir derivados de 2,5,6,7-tetranor-18,18,19,19-tetradeshidro-4,8-inter-m-fenileno-pgi2. (reserva del art. 167.2 cpe). - Google Patents
Procedimiento para producir derivados de 2,5,6,7-tetranor-18,18,19,19-tetradeshidro-4,8-inter-m-fenileno-pgi2. (reserva del art. 167.2 cpe).Info
- Publication number
- ES2032427T3 ES2032427T3 ES198787118053T ES87118053T ES2032427T3 ES 2032427 T3 ES2032427 T3 ES 2032427T3 ES 198787118053 T ES198787118053 T ES 198787118053T ES 87118053 T ES87118053 T ES 87118053T ES 2032427 T3 ES2032427 T3 ES 2032427T3
- Authority
- ES
- Spain
- Prior art keywords
- pgi2
- tetradeshidro
- fenileno
- tetranor
- cpe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229960001123 epoprostenol Drugs 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 230000001766 physiological effect Effects 0.000 abstract 1
- 150000003174 prostaglandin I2 derivatives Chemical class 0.000 abstract 1
- KAQKFAOMNZTLHT-OZUDYXHBSA-M prostaglandin I2(1-) Chemical compound O1\C(=C/CCCC([O-])=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-OZUDYXHBSA-M 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Photoreceptors In Electrophotography (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP29536786 | 1986-12-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2032427T3 true ES2032427T3 (es) | 1993-02-16 |
Family
ID=17819706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198787118053T Expired - Lifetime ES2032427T3 (es) | 1986-12-11 | 1987-12-07 | Procedimiento para producir derivados de 2,5,6,7-tetranor-18,18,19,19-tetradeshidro-4,8-inter-m-fenileno-pgi2. (reserva del art. 167.2 cpe). |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4880939A (enExample) |
| EP (1) | EP0274064B1 (enExample) |
| JP (1) | JPS63264475A (enExample) |
| KR (1) | KR930003853B1 (enExample) |
| AT (1) | ATE73768T1 (enExample) |
| AU (1) | AU600054B2 (enExample) |
| CA (1) | CA1291131C (enExample) |
| DE (1) | DE3777590D1 (enExample) |
| ES (1) | ES2032427T3 (enExample) |
| ZA (1) | ZA879186B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5401768A (en) * | 1987-10-16 | 1995-03-28 | Toray Industries, Inc. | 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2, derivative, manufacturing process thereof and its use |
| WO1990010003A1 (en) * | 1989-02-27 | 1990-09-07 | Toray Industries, Inc. | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI2 DERIVATIVES |
| US5086071A (en) * | 1989-03-14 | 1992-02-04 | Toray Industries, Inc. | 2,5,6,7-tetranor-4,8-inter-m-phenylene pgi2 derivatives |
| US5233059A (en) * | 1991-07-25 | 1993-08-03 | Iowa State University Research Foundation, Inc. | Synthesis of benzoprostacyclins using palladium catalysis |
| WO1998040073A1 (fr) * | 1997-03-13 | 1998-09-17 | Toray Industries, Inc. | Medicament pour traiter les lesions vasculaires diabetiques |
| WO1999013881A1 (en) * | 1997-09-17 | 1999-03-25 | Toray Industries, Inc. | Cervical maturing agent |
| CN105315247B (zh) | 2011-06-16 | 2019-07-26 | 琅歌生物技术股份有限公司 | 贝前列素的生产方法 |
| WO2013040068A2 (en) * | 2011-09-12 | 2013-03-21 | Irix Pharmaceuticals, Inc. | Process for preparing synthetic prostacyclins |
| US9765047B2 (en) | 2015-08-12 | 2017-09-19 | United Therapeutics Corporation | Process for making beraprost |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5931510B2 (ja) * | 1979-09-03 | 1984-08-02 | 東レ株式会社 | ５，６，７−トリノル−４，８−インタ−ｍ−フエニレンＰＧＩ↓２誘導体 |
| DE3041601A1 (de) * | 1980-10-31 | 1982-06-16 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue prostacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3147714A1 (de) * | 1981-11-27 | 1983-06-01 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue prostacycline und verfahren zu ihrer herstellung |
| JPS58124778A (ja) * | 1982-01-20 | 1983-07-25 | Toray Ind Inc | ５，６，７−トリノル−４，８−インタ−ｍ−フエニレンＰＧＩ↓２誘導体 |
-
1987
- 1987-12-04 US US07/128,878 patent/US4880939A/en not_active Expired - Lifetime
- 1987-12-07 EP EP87118053A patent/EP0274064B1/en not_active Expired - Lifetime
- 1987-12-07 ES ES198787118053T patent/ES2032427T3/es not_active Expired - Lifetime
- 1987-12-07 DE DE8787118053T patent/DE3777590D1/de not_active Expired - Fee Related
- 1987-12-07 ZA ZA879186A patent/ZA879186B/xx unknown
- 1987-12-07 AT AT87118053T patent/ATE73768T1/de not_active IP Right Cessation
- 1987-12-10 CA CA000554050A patent/CA1291131C/en not_active Expired - Fee Related
- 1987-12-10 AU AU82420/87A patent/AU600054B2/en not_active Ceased
- 1987-12-11 KR KR1019870014231A patent/KR930003853B1/ko not_active Expired - Fee Related
- 1987-12-11 JP JP62313957A patent/JPS63264475A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| CA1291131C (en) | 1991-10-22 |
| EP0274064A3 (en) | 1988-07-27 |
| KR880007453A (ko) | 1988-08-27 |
| AU8242087A (en) | 1988-06-16 |
| ZA879186B (en) | 1988-06-06 |
| KR930003853B1 (ko) | 1993-05-14 |
| JPS63264475A (ja) | 1988-11-01 |
| JPH0571592B2 (enExample) | 1993-10-07 |
| DE3777590D1 (de) | 1992-04-23 |
| EP0274064B1 (en) | 1992-03-18 |
| EP0274064A2 (en) | 1988-07-13 |
| US4880939A (en) | 1989-11-14 |
| ATE73768T1 (de) | 1992-04-15 |
| AU600054B2 (en) | 1990-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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