ES2032413T3 - Procedimiento para preparar pirimidoquinoxalinas sustituidas. (reserva del art. 167.2 cpe). - Google Patents

Procedimiento para preparar pirimidoquinoxalinas sustituidas. (reserva del art. 167.2 cpe).

Info

Publication number
ES2032413T3
ES2032413T3 ES198787111892T ES87111892T ES2032413T3 ES 2032413 T3 ES2032413 T3 ES 2032413T3 ES 198787111892 T ES198787111892 T ES 198787111892T ES 87111892 T ES87111892 T ES 87111892T ES 2032413 T3 ES2032413 T3 ES 2032413T3
Authority
ES
Spain
Prior art keywords
pyrimidoquinoxalinas
cpe
reservation
procedure
art
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787111892T
Other languages
English (en)
Inventor
George John Ellames
Kevin Robert Lawson
Albert Andrej Jaxa-Chamiec
Roger Munro Upton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of ES2032413T3 publication Critical patent/ES2032413T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

ESTA MEMORIA SE REFIERE A UNA NUEVA CLASE DE DERIVADOS DE QUINOXALINA SUSTITUIDOS DE FORMULA (I) EN LA QUE R1 Y R2 SON, INDEPENDIENTEMENTE, HIDROGENO O ALQUILO; R3 Y R4 ESTAN SELECCIONADAS, INDEPENDIENTEMENTE, DE LA CLASE QUE CONSISTE EN HIDROGENO, HALOGENO, ALQUILO Y ALCOXI; R5 ES HALOGENO O TRIFLUOROMETILO. LA MEMORIA SE REFIERE, ADEMAS, A COMPOSICIONES FARMACEUTICAS QUE CONTIENEN TALES COMPUESTOS Y AL USO DE TALES COMPUESTOS Y COMPOSICIONES COMO AGENTES ANTIANAEROBIOS.
ES198787111892T 1986-08-18 1987-08-17 Procedimiento para preparar pirimidoquinoxalinas sustituidas. (reserva del art. 167.2 cpe). Expired - Lifetime ES2032413T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/897,461 US4758565A (en) 1986-08-18 1986-08-18 Substituted pyrimidoquinoxalines useful as anti-anaerobic agents

Publications (1)

Publication Number Publication Date
ES2032413T3 true ES2032413T3 (es) 1993-02-16

Family

ID=25407933

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787111892T Expired - Lifetime ES2032413T3 (es) 1986-08-18 1987-08-17 Procedimiento para preparar pirimidoquinoxalinas sustituidas. (reserva del art. 167.2 cpe).

Country Status (8)

Country Link
US (1) US4758565A (es)
EP (1) EP0256545B1 (es)
JP (1) JP2566974B2 (es)
AT (1) ATE74604T1 (es)
CA (1) CA1296334C (es)
DE (1) DE3778088D1 (es)
ES (1) ES2032413T3 (es)
GR (1) GR3004321T3 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9114426D0 (en) * 1991-07-03 1991-08-21 Nat Res Dev Compounds useful for treating tumours ii

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472401A (en) * 1981-11-27 1984-09-18 Roussel Uclaf Pyrimido-quinoxalines having antiallergic properties
US4510143A (en) * 1982-02-17 1985-04-09 Roussel Uclaf Antiallergic pyrimido[1,2-a]quinoxalin-2-carboxylic acid derivatives
US4696928A (en) * 1985-09-09 1987-09-29 G. D. Searle & Co. Substituted dihydroimidazo[1,2-a]quinoxalines

Also Published As

Publication number Publication date
US4758565A (en) 1988-07-19
JP2566974B2 (ja) 1996-12-25
GR3004321T3 (es) 1993-03-31
ATE74604T1 (de) 1992-04-15
EP0256545B1 (en) 1992-04-08
JPS6399072A (ja) 1988-04-30
EP0256545A1 (en) 1988-02-24
DE3778088D1 (de) 1992-05-14
CA1296334C (en) 1992-02-25

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