ES2032312T3 - 5-fenil-1,2,3a,4,5,9b-hexahidro-3h-ben(e)indoles, su obtencion y empleo como medicamentos. - Google Patents

5-fenil-1,2,3a,4,5,9b-hexahidro-3h-ben(e)indoles, su obtencion y empleo como medicamentos.

Info

Publication number
ES2032312T3
ES2032312T3 ES198888107782T ES88107782T ES2032312T3 ES 2032312 T3 ES2032312 T3 ES 2032312T3 ES 198888107782 T ES198888107782 T ES 198888107782T ES 88107782 T ES88107782 T ES 88107782T ES 2032312 T3 ES2032312 T3 ES 2032312T3
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
phenyl
hexahidro
indoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888107782T
Other languages
English (en)
Inventor
Gerd Dr. Steiner
Walter Dr. Himmele
Ernst Dr. Buschmann
Hans-Juergen Dr. Teschendorf
Harald Dr. Weifenbach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2032312T3 publication Critical patent/ES2032312T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

Abstract

SE DESCRIBEN 5-FENIL-1,2,3A,4,5,9A-HEXAHIDRO-3H-BENZO-INDOLES DE FORMULA (I), DONDE R1-R5 TIENEN EL SIGNIFICADO QUE SE INDICA EN LA DESCRIPCION, ASI COMO SU OBTENCION. ESTAS SUSTANCIAS RESULTAN ADECUADAS PARA COMBATIR ENFERMEDADES.
ES198888107782T 1987-05-23 1988-05-14 5-fenil-1,2,3a,4,5,9b-hexahidro-3h-ben(e)indoles, su obtencion y empleo como medicamentos. Expired - Lifetime ES2032312T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873717395 DE3717395A1 (de) 1987-05-23 1987-05-23 5-phenyl-1,2,3a,4,5,9b-hexahydro-3h-benz(e) indole, ihre herstellung und verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ES2032312T3 true ES2032312T3 (es) 1993-02-01

Family

ID=6328243

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888107782T Expired - Lifetime ES2032312T3 (es) 1987-05-23 1988-05-14 5-fenil-1,2,3a,4,5,9b-hexahidro-3h-ben(e)indoles, su obtencion y empleo como medicamentos.

Country Status (8)

Country Link
US (1) US4877807A (es)
EP (1) EP0292819B1 (es)
JP (1) JPH01117862A (es)
AT (1) ATE74593T1 (es)
CA (1) CA1311762C (es)
DE (2) DE3717395A1 (es)
ES (1) ES2032312T3 (es)
FI (1) FI88154C (es)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4930836B1 (es) * 1971-07-22 1974-08-16
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
US4678791A (en) * 1985-05-07 1987-07-07 Pennwalt Corporation 6-phenyl-1,2-3,4,4a,5-6,10b-octahydrobenz(h)isoquinolines useful for treating depression
DE3632589A1 (de) * 1985-10-18 1987-04-23 Bayer Ag Verfahren zur herstellung von (gamma)-butyrolactamen
DE3537075A1 (de) * 1985-10-18 1987-04-23 Bayer Ag Verfahren zur herstellung von clausenamid

Also Published As

Publication number Publication date
DE3717395A1 (de) 1988-12-08
US4877807A (en) 1989-10-31
FI88154C (fi) 1993-04-13
EP0292819A2 (de) 1988-11-30
DE3869830D1 (de) 1992-05-14
FI882421A0 (fi) 1988-05-23
FI88154B (fi) 1992-12-31
FI882421A (fi) 1988-11-24
JPH01117862A (ja) 1989-05-10
CA1311762C (en) 1992-12-22
EP0292819B1 (de) 1992-04-08
ATE74593T1 (de) 1992-04-15
EP0292819A3 (en) 1989-07-12

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