ES2020508B3 - Derivados citoprotectores utiles para enfermedades isquemicas, su preparacion y composiciones que los contienen. - Google Patents
Derivados citoprotectores utiles para enfermedades isquemicas, su preparacion y composiciones que los contienen.Info
- Publication number
- ES2020508B3 ES2020508B3 ES86117895T ES86117895T ES2020508B3 ES 2020508 B3 ES2020508 B3 ES 2020508B3 ES 86117895 T ES86117895 T ES 86117895T ES 86117895 T ES86117895 T ES 86117895T ES 2020508 B3 ES2020508 B3 ES 2020508B3
- Authority
- ES
- Spain
- Prior art keywords
- methyl
- hydrogen
- useful
- group
- cytoprotectors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT23373/85A IT1201511B (it) | 1985-12-23 | 1985-12-23 | Derivati citoprotettivi in patologie a base ischemica,loro preparazione e composizioni che li cntengono |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2020508B3 true ES2020508B3 (es) | 1991-08-16 |
Family
ID=11206518
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES86117895T Expired - Lifetime ES2020508B3 (es) | 1985-12-23 | 1986-12-22 | Derivados citoprotectores utiles para enfermedades isquemicas, su preparacion y composiciones que los contienen. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4789681A (es) |
EP (1) | EP0230037B1 (es) |
JP (1) | JPS62158249A (es) |
AT (1) | ATE61347T1 (es) |
CA (1) | CA1284646C (es) |
DE (1) | DE3677943D1 (es) |
ES (1) | ES2020508B3 (es) |
GR (1) | GR3001879T3 (es) |
IT (1) | IT1201511B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5028627A (en) * | 1989-09-13 | 1991-07-02 | Cornell Research Foundation, Inc. | Method of using arginine derivatives to inhibit systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor |
US5770623A (en) * | 1989-09-13 | 1998-06-23 | Board Of Regents, The University Of Texas System | Argine antagonists for inhibition of systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor |
GB8929076D0 (en) * | 1989-12-22 | 1990-02-28 | Scras | Treatment of shock by blocking agents of edrf effect or formation |
US5710324A (en) * | 1990-02-26 | 1998-01-20 | Merrell Pharmaceuticals Inc. | Inhibitors of nitric oxide biosynthesis |
US5318992A (en) * | 1990-02-26 | 1994-06-07 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of nitric oxide biosynthesis |
AU636713B2 (en) * | 1990-02-26 | 1993-05-06 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of nitric oxide biosynthesis |
US5585402A (en) * | 1992-12-23 | 1996-12-17 | Glaxo Wellcome Inc. | Nitric oxide synthase inhibitors |
AU6950294A (en) * | 1993-05-14 | 1994-12-12 | Amira, Inc. | Treating body parts susceptible to ischemia using creatine analogs |
GB9312761D0 (en) * | 1993-06-21 | 1993-08-04 | Wellcome Found | Amino acid derivatives |
PT793646E (pt) | 1994-11-23 | 2002-03-28 | Biovitrum Ab | Carboxilatos de aminoguanidina destinados ao tratamento de diabetes mellitus nao-insulinodependente |
WO1996018607A1 (fr) * | 1994-12-12 | 1996-06-20 | Chugai Seiyaku Kabushiki Kaisha | Derive d'aniline inhibant la synthase du monoxyde d'azote |
DE19544685A1 (de) * | 1995-11-30 | 1997-06-05 | Thomae Gmbh Dr K | Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
DE19544686A1 (de) * | 1995-11-30 | 1997-06-05 | Thomae Gmbh Dr K | Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
US5955617A (en) * | 1996-05-21 | 1999-09-21 | Pharmacia & Upjohn Company | Aminoguanidine carboxylate lactams for the treatment of non-insulin-dependent diabetes mellitus |
WO2000010546A2 (en) * | 1998-08-25 | 2000-03-02 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | D-arginine for the treatment of neorodegenerative diseases |
WO2006051314A2 (en) * | 2004-11-12 | 2006-05-18 | Ucl Business Plc | Guanidine derivatives as inhibitors of ddah |
CN109593052B (zh) * | 2018-11-20 | 2021-04-20 | 首都医科大学 | 用于诊断和治疗的放射性精氨酸衍生物及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1195303B (de) * | 1964-04-16 | 1965-06-24 | Bayer Ag | Verfahren zur Herstellung von tetracyclischen und pentacyclischen Triterpenamidino-hydrazonen |
US3576844A (en) * | 1966-10-13 | 1971-04-27 | Sumitomo Chemical Co | N-alkoxycarbonyl-aminoalkyl guanidines |
FR2390954A1 (fr) * | 1976-10-13 | 1978-12-15 | Choay Sa | Nouvelles guanylhydrazones, leurs procedes de preparation et medicaments les contenant |
IT1127321B (it) * | 1979-12-28 | 1986-05-21 | Italfarmaco Spa | Composizione farmaceutiche aventi specifiche proprieta' terapeutiche nei confronti dell'edema polmonare acuto,di alcuni stati di shock e dell'iperfibrinolisi |
IT1127322B (it) * | 1979-12-28 | 1986-05-21 | Italfarmaco Spa | Composizioni farmaceutiche con esaltazione dell'attivita' terapeutica di cortisonici |
US4499068A (en) * | 1982-08-26 | 1985-02-12 | Johnson & Johnson Products, Inc. | Oral compositions comprising NG -alkyl derivatives of arginine |
US4477429A (en) * | 1982-08-26 | 1984-10-16 | Johnson & Johnson Products, Inc. | Oral compositions comprising N.sup.α -alkyl derivatives of arginine |
-
1985
- 1985-12-23 IT IT23373/85A patent/IT1201511B/it active
-
1986
- 1986-12-22 DE DE8686117895T patent/DE3677943D1/de not_active Expired - Fee Related
- 1986-12-22 AT AT86117895T patent/ATE61347T1/de not_active IP Right Cessation
- 1986-12-22 US US06/944,949 patent/US4789681A/en not_active Expired - Fee Related
- 1986-12-22 EP EP86117895A patent/EP0230037B1/en not_active Expired - Lifetime
- 1986-12-22 JP JP61306184A patent/JPS62158249A/ja active Pending
- 1986-12-22 ES ES86117895T patent/ES2020508B3/es not_active Expired - Lifetime
- 1986-12-23 CA CA000526235A patent/CA1284646C/en not_active Expired - Fee Related
-
1991
- 1991-04-29 GR GR91400552T patent/GR3001879T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE61347T1 (de) | 1991-03-15 |
IT8523373A0 (it) | 1985-12-23 |
EP0230037B1 (en) | 1991-03-06 |
DE3677943D1 (de) | 1991-04-11 |
IT1201511B (it) | 1989-02-02 |
EP0230037A1 (en) | 1987-07-29 |
CA1284646C (en) | 1991-06-04 |
US4789681A (en) | 1988-12-06 |
GR3001879T3 (en) | 1992-11-23 |
JPS62158249A (ja) | 1987-07-14 |
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