ES2016427A6 - Un procedimiento para la obtencion de una linea celular hibrida. - Google Patents

Un procedimiento para la obtencion de una linea celular hibrida.

Info

Publication number
ES2016427A6
ES2016427A6 ES8803362A ES8803362A ES2016427A6 ES 2016427 A6 ES2016427 A6 ES 2016427A6 ES 8803362 A ES8803362 A ES 8803362A ES 8803362 A ES8803362 A ES 8803362A ES 2016427 A6 ES2016427 A6 ES 2016427A6
Authority
ES
Spain
Prior art keywords
monoclonal antibody
cell line
hiv
bind
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES8803362A
Other languages
English (en)
Inventor
Kenneth H Kortright
David E Hofheinz
Carole Sullivan
Gary P Toedter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coulter Corp
Original Assignee
Coulter Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coulter Corp filed Critical Coulter Corp
Publication of ES2016427A6 publication Critical patent/ES2016427A6/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

UN PROCEDIMIENTO PARA LA OBTENCION DE UNA LINEA CELULAR HIBRIDA. UN PROCEDIMIENTO PARA LA OBTENCION DE UNA LINEA CELULAR HIBRIDA QUE PRODUCE UN ANTICUERPO MONOCLONAL ESPECIFICO DE ANTIGENOS DEL NUCLEO DE HIV. EL PROCEDIMIENTO DE ESTA INVENCION UTILIZA UN PROTOCOLO UNICO DE INMUNIZACION EN EL QUE UNOS RATONES BALB/C SE INMUNIZAN MEDIANTE UNA SERIE DE INFUSIONES MULTIPLES EMPLEANDO MULTIPLES AISLADOS VIRICOS; LAS CELULAS PRODUCTORAS DE ANTICUERPO PROCEDENTES DEL ANIMAL INMUNIZADO SE FUSIONAN CON CELULAS DE UNA LINEA CELULAR INMORTAL; SE CULTIVAN LAS CELULAS FUSIONADAS Y SE SELECCIONAN CULTIVOS DE LAS LINEAS CELULARES HIBRIDAS QUE PRODUCEN EL ANTICUERPO MONOCLONAL ESPECIFICO DE ANTIGENOS DEL NUCLEO DE HIV.
ES8803362A 1987-11-06 1988-11-04 Un procedimiento para la obtencion de una linea celular hibrida. Expired - Fee Related ES2016427A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/118,145 US4888290A (en) 1987-11-06 1987-11-06 Monoclonal antibody specific to HIV antigens

Publications (1)

Publication Number Publication Date
ES2016427A6 true ES2016427A6 (es) 1990-11-01

Family

ID=22376739

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8803362A Expired - Fee Related ES2016427A6 (es) 1987-11-06 1988-11-04 Un procedimiento para la obtencion de una linea celular hibrida.

Country Status (13)

Country Link
US (1) US4888290A (es)
EP (1) EP0415920B1 (es)
JP (1) JP2710972B2 (es)
KR (1) KR960016304B1 (es)
CN (1) CN1025219C (es)
AU (1) AU612686B2 (es)
CA (1) CA1339350C (es)
DE (1) DE3854502T2 (es)
ES (1) ES2016427A6 (es)
IE (1) IE61241B1 (es)
IL (1) IL87535A (es)
WO (1) WO1989004376A1 (es)
ZA (1) ZA884651B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104790A (en) * 1987-06-29 1992-04-14 Genetic Systems Corporation Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
US4886742A (en) * 1987-06-15 1989-12-12 Coulter Corporation Enzyme immunoassay for detecting HIV antigens in human sera
ZA903492B (en) * 1989-05-15 1991-02-27 Akzo Nv T-lymphotropic retrovirus monoclonal antibodies
US5210181A (en) * 1989-05-15 1993-05-11 Akzo N.V. T-lymphotropic retrovirus peptide
DE69112059T2 (de) * 1990-06-01 1996-02-29 Lepetit Spa Monoklonale antikörper gegen gag-protein-vorläufer-p55 von hiv-virus.
US5164293A (en) * 1990-09-25 1992-11-17 Coulter Corporation Monoclonal antibody for detecting HTLV-I, HTLV-II and STLV-I viruses
EP0519866A1 (en) * 1991-06-18 1992-12-23 Ciba-Geigy Ag Novel anti-HIV antibodies
US5451525A (en) * 1992-02-14 1995-09-19 Coulter Corporation Method and materials for determining particle count in a flow cytometer
US6319665B1 (en) 1994-06-07 2001-11-20 Inverness Medical Technology, Inc. Home test kit and method with telephone verification of results
AU5082698A (en) * 1996-10-23 1998-05-15 Oravax, Inc Heat inactivation of viruses in antibody preparations
US5891994A (en) * 1997-07-11 1999-04-06 Thymon L.L.C. Methods and compositions for impairing multiplication of HIV-1
US5902722A (en) * 1997-12-05 1999-05-11 The Perkin-Elmer Corporation Method of detecting organisms in a sample
US5915307A (en) * 1998-01-29 1999-06-29 Suncast Corporation Sports shelf
NO311807B1 (no) * 1999-03-04 2002-01-28 Bionor Immuno As HIV-peptider, antigener, vaksinepreparater, immunoassay- testsett og en metode for påvisning av antistoffer fremkalt av HIV
US6399067B1 (en) * 2000-04-28 2002-06-04 Thymon L.L.C. Methods and compositions for impairing multiplication of HIV-1
US6818392B2 (en) * 2000-12-06 2004-11-16 Abbott Laboratories Monoclonal antibodies to human immunodeficiency virus and uses thereof
EP1851247A2 (en) 2005-02-15 2007-11-07 Thymon L.L.C. Methods and compositions for impairing multiplication of hiv-1
US20080108054A1 (en) * 2006-08-28 2008-05-08 Jayasri Basu Detecting early HIV infection in genital tract cells and secretions
WO2011119920A2 (en) 2010-03-25 2011-09-29 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
DK2691530T3 (en) 2011-06-10 2018-05-22 Univ Oregon Health & Science CMV GLYCOPROTEIN AND RECOMBINANT VECTORS
AU2012216792A1 (en) 2011-09-12 2013-03-28 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
EP2848937A1 (en) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Methods of identifying novel HIV-1 immunogens
EP2873423B1 (en) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
EP3069730A3 (en) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
EP3072901A1 (en) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
CN110669133A (zh) * 2019-10-18 2020-01-10 普健生物（武汉）科技有限公司 利用尾静脉注射进行基因免疫开发小鼠单克隆抗体的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences

Also Published As

Publication number Publication date
US4888290A (en) 1989-12-19
ZA884651B (en) 1990-03-28
KR890701771A (ko) 1989-12-21
AU612686B2 (en) 1991-07-18
CN1025219C (zh) 1994-06-29
KR960016304B1 (ko) 1996-12-09
IE881799L (en) 1989-05-06
IL87535A (en) 1993-01-14
CA1339350C (en) 1997-08-26
IE61241B1 (en) 1994-10-19
AU2133788A (en) 1989-06-01
WO1989004376A1 (en) 1989-05-18
EP0415920A4 (en) 1993-03-17
JP2710972B2 (ja) 1998-02-10
DE3854502T2 (de) 1996-04-18
EP0415920A1 (en) 1991-03-13
EP0415920B1 (en) 1995-09-20
JPH03500483A (ja) 1991-02-07
DE3854502D1 (de) 1995-10-26
IL87535A0 (en) 1989-01-31
CN1033071A (zh) 1989-05-24

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2008-11-04

FD1A Patent lapsed

Effective date: 19961105