ES2010283A6 - Procedimiento para preparar derivados de somatostatina. - Google Patents
Procedimiento para preparar derivados de somatostatina.Info
- Publication number
- ES2010283A6 ES2010283A6 ES8802038A ES8802038A ES2010283A6 ES 2010283 A6 ES2010283 A6 ES 2010283A6 ES 8802038 A ES8802038 A ES 8802038A ES 8802038 A ES8802038 A ES 8802038A ES 2010283 A6 ES2010283 A6 ES 2010283A6
- Authority
- ES
- Spain
- Prior art keywords
- formula
- protected
- polypeptide
- link
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- -1 MERCAPTO GROUPS Chemical group 0.000 abstract 1
- 102000007079 Peptide Fragments Human genes 0.000 abstract 1
- 108010033276 Peptide Fragments Proteins 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical class C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3721406 | 1987-06-29 | ||
| DE3721407 | 1987-06-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2010283A6 true ES2010283A6 (es) | 1989-11-01 |
Family
ID=25857047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8802038A Expired ES2010283A6 (es) | 1987-06-29 | 1988-06-29 | Procedimiento para preparar derivados de somatostatina. |
Country Status (15)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU906340D0 (en) * | 1986-10-13 | 1991-04-29 | Sandoz Ag | Synthesis in solid phase for producing peptonic alcohols |
| GB8826452D0 (en) * | 1988-11-11 | 1988-12-14 | Sandoz Ltd | Peptide derivatives |
| GB8813339D0 (en) * | 1988-06-06 | 1988-07-13 | Sandoz Ltd | Improvements in/relating to organic compounds |
| MY106120A (en) * | 1988-12-05 | 1995-03-31 | Novartis Ag | Peptide derivatives. |
| US5753627A (en) * | 1988-12-05 | 1998-05-19 | Novartis Ag | Use of certain complexed somatostatin peptides for the invivo imaging of somatostatin receptor-positive tumors and metastasis |
| US5776894A (en) * | 1988-12-05 | 1998-07-07 | Novartis Ag | Chelated somatostatin peptides and complexes thereof, pharmaceutical compositions containing them and their use in treating tumors |
| US5633263A (en) * | 1989-04-26 | 1997-05-27 | The Administrators Of The Tulane Educational Fund | Linear somatostatin analogs |
| KR0173119B1 (ko) * | 1989-04-26 | 1999-02-01 | 닐 에이. 밴스로우 | 선형 소마토스타틴 유사체 |
| GB9004017D0 (en) * | 1990-02-22 | 1990-04-18 | Krenning Eric P | Improvements in or relating to organic compounds |
| US5632969A (en) * | 1994-10-13 | 1997-05-27 | Merck & Co., Inc. | N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications |
| US5556939A (en) * | 1994-10-13 | 1996-09-17 | Merck Frosst Canada, Inc. | TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications |
| AUPN999096A0 (en) * | 1996-05-22 | 1996-06-13 | Northstar Biologicals Pty Ltd | Peptides, antibodies, vaccines & uses thereof |
| DE60018937T2 (de) * | 2000-07-31 | 2006-03-30 | Dabur Research Foundation | Somatostatin analoge und deren verwendung zur behandlung von krebs |
| AU2002258465B2 (en) | 2001-03-08 | 2006-01-19 | The Administrators Of The Tulane Educational Fund | Somatostatin antagonists |
| JP2004531520A (ja) * | 2001-04-09 | 2004-10-14 | ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド | ソマトスタチンアゴニスト |
| KR100432178B1 (ko) * | 2002-01-29 | 2004-05-22 | 홍수천 | 철제배관의 부식방지능을 갖는 수정화 장치 |
| KR100462968B1 (ko) * | 2002-06-10 | 2004-12-23 | 주식회사 리독스 | 배관내의 물의 살균, 악취제거 및 스케일 발생 방지를위한 수처리 장치 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU85269A1 (fr) * | 1984-03-26 | 1985-10-14 | Techland S A | Composes nouveaux de somatostatine,procede pour leur synthese,preparation a usage veterinaire contenant lesdits composes et procede pour le traitement d'animaux |
| HUT42101A (en) * | 1985-01-07 | 1987-06-29 | Sandoz Ag | Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds |
-
1988
- 1988-06-24 CH CH2423/88A patent/CH679045A5/de not_active IP Right Cessation
- 1988-06-27 FR FR888808720A patent/FR2617171B1/fr not_active Expired - Fee Related
- 1988-06-27 AU AU18409/88A patent/AU1840988A/en not_active Abandoned
- 1988-06-27 IL IL86876A patent/IL86876A0/xx unknown
- 1988-06-27 DK DK353788A patent/DK353788A/da not_active Application Discontinuation
- 1988-06-27 GB GB8815257A patent/GB2206352B/en not_active Expired - Lifetime
- 1988-06-27 BE BE8800732A patent/BE1002663A4/fr not_active IP Right Cessation
- 1988-06-27 NZ NZ225188A patent/NZ225188A/en unknown
- 1988-06-28 IT IT48133/88A patent/IT1221065B/it active
- 1988-06-28 SE SE8802413A patent/SE8802413L/ not_active Application Discontinuation
- 1988-06-28 LU LU87262A patent/LU87262A1/fr unknown
- 1988-06-28 NL NL8801640A patent/NL8801640A/nl not_active Application Discontinuation
- 1988-06-28 JP JP63162370A patent/JPS6426599A/ja active Pending
- 1988-06-28 KR KR1019880007817A patent/KR890000520A/ko not_active Withdrawn
- 1988-06-29 ES ES8802038A patent/ES2010283A6/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU1840988A (en) | 1989-01-05 |
| GB2206352A (en) | 1989-01-05 |
| FR2617171B1 (fr) | 1994-10-14 |
| BE1002663A4 (fr) | 1991-04-30 |
| CH679045A5 (enrdf_load_stackoverflow) | 1991-12-13 |
| IT8848133A0 (it) | 1988-06-28 |
| SE8802413L (sv) | 1988-12-30 |
| NZ225188A (en) | 1991-04-26 |
| LU87262A1 (fr) | 1989-03-08 |
| SE8802413D0 (sv) | 1988-06-28 |
| IL86876A0 (en) | 1988-11-30 |
| IT1221065B (it) | 1990-06-21 |
| KR890000520A (ko) | 1989-03-15 |
| FR2617171A1 (fr) | 1988-12-30 |
| JPS6426599A (en) | 1989-01-27 |
| DK353788D0 (da) | 1988-06-27 |
| DK353788A (da) | 1988-12-30 |
| GB8815257D0 (en) | 1988-08-03 |
| NL8801640A (nl) | 1989-01-16 |
| GB2206352B (en) | 1990-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| SA6 | Expiration date (snapshot 920101) |
Free format text: 2008-06-29 |
|
| FD1A | Patent lapsed |
Effective date: 20000201 |