ES2007252A6 - Metodo para preparar derivados de acido nucleico. - Google Patents
Metodo para preparar derivados de acido nucleico.Info
- Publication number
- ES2007252A6 ES2007252A6 ES8802078A ES8802078A ES2007252A6 ES 2007252 A6 ES2007252 A6 ES 2007252A6 ES 8802078 A ES8802078 A ES 8802078A ES 8802078 A ES8802078 A ES 8802078A ES 2007252 A6 ES2007252 A6 ES 2007252A6
- Authority
- ES
- Spain
- Prior art keywords
- nucleic acid
- acid derivatives
- ion
- preparation
- exchange
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
UN METODO PARA PRODUCIR POLIMEROS DE ACIDOS NUCLEICOS BICATENARIOS DIMENSIONADOS, EN QUE LOS POLIMEROS DE ACIDOS NUCLEICOS MONOCATENARIOS SON DIMENSIONADOS Y LUEGO REANILLADOS. POR ESTE METODO SE PUEDEN OBTENER DERIVADOS DE ACIDOS NUCLEICOS BICATENARIOS QUE TIENEN ARN COMO EL CUERPO PROGENITOR, CUYA DISTRIBUCION TOTAL DE TAMAÑOS MOLECULARES CAE DENTRO DEL INTERVALO ENTRE 4S Y 13S COMO EL VALOR DE LA CONSTANTE DE SEDIMENTACION DEL MISMO, ASI COMO AQUELLOS EN QUE LAS MOLECULAS PARA LA MAXIMA DISTRIBUCION EN TODA LA DISTRIBUCION DE TAMAÑOS MOLECULARES DE LOS DERIVADOS POR ENCIMA DEL NUMERO DE BASES, CAE DENTRO DEL INTERVALO ENTRE 500 Y 10.000. EL PROCEDIMIENTO ES INDUSTRIALMENTE VENTAJOSO, PUESTO QUE ES ALTA LA VELOCIDAD DE REACCION Y ES ALTO EL RENDIMIENTO DE LOS PRODUCTOS. LOS PRODUCTOS SON UTILIZABLES COMO INGREDIENTE ACTIVO PARA UNA COMPOSICION ANTITUMORAL O UNA COMPOSICION ANTIVIRICA, PUESTO QUE TIENEN ACTIVIDADES FISIOLOGICAS Y SON ESCASAMENTE TOXICOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16743487 | 1987-07-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2007252A6 true ES2007252A6 (es) | 1989-06-01 |
Family
ID=15849635
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8802078A Expired ES2007252A6 (es) | 1987-07-03 | 1988-07-01 | Metodo para preparar derivados de acido nucleico. |
Country Status (19)
Country | Link |
---|---|
KR (1) | KR890002226A (es) |
CN (1) | CN1024556C (es) |
AT (1) | AT397658B (es) |
AU (1) | AU1864488A (es) |
CH (1) | CH676123A5 (es) |
DE (1) | DE3822406A1 (es) |
DK (1) | DK369088A (es) |
ES (1) | ES2007252A6 (es) |
FI (1) | FI883163A (es) |
FR (1) | FR2617403B1 (es) |
GB (1) | GB2207138B (es) |
HU (1) | HU202250B (es) |
IL (1) | IL86884A0 (es) |
IT (1) | IT1224504B (es) |
NL (1) | NL8801664A (es) |
NO (1) | NO882922L (es) |
PT (1) | PT87903B (es) |
SE (1) | SE8802480L (es) |
ZA (1) | ZA884698B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4963532A (en) * | 1987-11-25 | 1990-10-16 | Hem Research, Inc. | dsRNA-based prevention of viral escape |
KR100644172B1 (ko) | 1998-05-25 | 2006-11-10 | 니뽄 신야쿠 가부시키가이샤 | 핵산 함유 복합체 제제의 제조 방법 |
ATE299885T1 (de) * | 1999-02-15 | 2005-08-15 | Nippon Shinyaku Co Ltd | Polynukleotide mit gekürzter kette und verfahren zu ihrer herstellung |
WO2014088087A1 (ja) | 2012-12-06 | 2014-06-12 | 協和発酵バイオ株式会社 | アジュバント用二重鎖リボ核酸 |
CN117517551A (zh) * | 2023-11-03 | 2024-02-06 | 成都迈科康生物科技有限公司 | 一种采用高效液相色谱法检测聚肌胞含量的方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ194880A (en) * | 1979-09-17 | 1983-07-15 | Merck & Co Inc | Interferon-inducing composition containing modified polyriboinosinic-polyribocytidylic acid |
-
1988
- 1988-06-27 GB GB8815262A patent/GB2207138B/en not_active Expired - Fee Related
- 1988-06-27 IL IL86884A patent/IL86884A0/xx unknown
- 1988-06-29 CH CH2467/88A patent/CH676123A5/fr not_active IP Right Cessation
- 1988-06-29 CN CN88104080A patent/CN1024556C/zh not_active Expired - Fee Related
- 1988-06-29 AT AT0169988A patent/AT397658B/de not_active IP Right Cessation
- 1988-06-30 NL NL8801664A patent/NL8801664A/nl not_active Application Discontinuation
- 1988-06-30 NO NO88882922A patent/NO882922L/no unknown
- 1988-06-30 ZA ZA884698A patent/ZA884698B/xx unknown
- 1988-07-01 SE SE8802480A patent/SE8802480L/xx not_active Application Discontinuation
- 1988-07-01 ES ES8802078A patent/ES2007252A6/es not_active Expired
- 1988-07-01 AU AU18644/88A patent/AU1864488A/en not_active Abandoned
- 1988-07-01 HU HU883461A patent/HU202250B/hu not_active IP Right Cessation
- 1988-07-01 IT IT8848147A patent/IT1224504B/it active
- 1988-07-01 FR FR8808938A patent/FR2617403B1/fr not_active Expired - Fee Related
- 1988-07-01 DK DK369088A patent/DK369088A/da not_active Application Discontinuation
- 1988-07-01 PT PT87903A patent/PT87903B/pt not_active IP Right Cessation
- 1988-07-01 DE DE3822406A patent/DE3822406A1/de not_active Withdrawn
- 1988-07-01 FI FI883163A patent/FI883163A/fi not_active IP Right Cessation
- 1988-07-02 KR KR1019880008258A patent/KR890002226A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FR2617403A1 (fr) | 1989-01-06 |
HUT48272A (en) | 1989-05-29 |
NO882922L (no) | 1989-01-04 |
PT87903B (pt) | 1995-03-01 |
SE8802480D0 (sv) | 1988-07-01 |
IT8848147A0 (it) | 1988-07-01 |
DK369088A (da) | 1989-01-04 |
FI883163A0 (fi) | 1988-07-01 |
FI883163A (fi) | 1989-01-04 |
DE3822406A1 (de) | 1989-01-12 |
NL8801664A (nl) | 1989-02-01 |
CN1030424A (zh) | 1989-01-18 |
IL86884A0 (en) | 1988-11-30 |
HU202250B (en) | 1991-02-28 |
PT87903A (pt) | 1989-06-30 |
CN1024556C (zh) | 1994-05-18 |
CH676123A5 (es) | 1990-12-14 |
GB2207138B (en) | 1992-02-05 |
ATA169988A (de) | 1993-10-15 |
ZA884698B (en) | 1989-03-29 |
GB2207138A (en) | 1989-01-25 |
GB8815262D0 (en) | 1988-08-03 |
AU1864488A (en) | 1989-04-27 |
FR2617403B1 (fr) | 1993-05-07 |
IT1224504B (it) | 1990-10-04 |
NO882922D0 (no) | 1988-06-30 |
SE8802480L (sv) | 1989-01-04 |
AT397658B (de) | 1994-06-27 |
DK369088D0 (da) | 1988-07-01 |
KR890002226A (ko) | 1989-04-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20010201 |