ES2002915A6 - Un procedimiento para la preparacion de un peptido de veneno de serpiente que detiene el crecimiento. - Google Patents
Un procedimiento para la preparacion de un peptido de veneno de serpiente que detiene el crecimiento.Info
- Publication number
- ES2002915A6 ES2002915A6 ES8603138A ES8603138A ES2002915A6 ES 2002915 A6 ES2002915 A6 ES 2002915A6 ES 8603138 A ES8603138 A ES 8603138A ES 8603138 A ES8603138 A ES 8603138A ES 2002915 A6 ES2002915 A6 ES 2002915A6
- Authority
- ES
- Spain
- Prior art keywords
- peptide
- procedure
- amino acids
- preparation
- snake
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 230000012010 growth Effects 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 4
- 230000010261 cell growth Effects 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 241000271537 Crotalus atrox Species 0.000 abstract 1
- 231100000433 cytotoxic Toxicity 0.000 abstract 1
- 230000001472 cytotoxic effect Effects 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000004128 high performance liquid chromatography Methods 0.000 abstract 1
- 230000003211 malignant effect Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/855—Proteins from animals other than mammals or birds
- Y10S530/856—Snakes; venom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/801,019 US4731439A (en) | 1985-11-22 | 1985-11-22 | Snake venom growth arresting peptide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2002915A6 true ES2002915A6 (es) | 1988-10-01 |
Family
ID=25179974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8603138A Expired ES2002915A6 (es) | 1985-11-22 | 1986-11-21 | Un procedimiento para la preparacion de un peptido de veneno de serpiente que detiene el crecimiento. |
Country Status (20)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990015072A1 (en) * | 1989-06-07 | 1990-12-13 | Genentech, Inc. | Platelet aggregation inhibitors and related molecules |
| WO1991001740A1 (en) * | 1989-08-05 | 1991-02-21 | Varánusz Gm | Process for producing pharmacosmetics |
| US5232911A (en) * | 1990-01-03 | 1993-08-03 | Ventech Research Inc. | Mixture of a non-covalent heterodimer complex and a basic amphiphatic peptide as cytotoxic agent |
| US5766897A (en) * | 1990-06-21 | 1998-06-16 | Incyte Pharmaceuticals, Inc. | Cysteine-pegylated proteins |
| ES2105284T3 (es) * | 1992-07-27 | 1997-10-16 | Pfizer | Polipeptido bloqueante de los canales de calcio procedente de agelenopsis aperta. |
| DE4433890C2 (de) * | 1994-09-22 | 1999-02-18 | Deutsches Krebsforsch | Konjugat aus einem Wirkstoff und einem nicht als körperfremd angesehenen, nativen Protein |
| SG129211A1 (en) * | 1997-11-06 | 2007-02-26 | Univ Singapore | Therapeutic molecules |
| BR0101088A (pt) * | 2001-03-19 | 2003-03-18 | Biolab Sanus Farmaceutica Ltda | Processo de isolamento e purificação de peptìdeos inibidores das vasopeptidases, com especificidade para o sìtio carboxìlico da enzima conversora da angiotensina, secretados pelas glândulas do veneno de serpentes (bpps), particularmente bothrops jararaca, ou produzidos endogenamente (evasins) possuindo ação vasodilatadora e anti-hipertensiva; processo de determinação da sequência de amido-ácidos dos peptìdios inibidores secretados pela glândula de veneno de serpentes (bpps) ou endógenos (evasins); processo de determinação da sequência de aminoácidos dos bpps por dedução do cdna dos precursores dessas moléculas expressos em tecidos de serpentes, especificamente bothrops jararaca. processo de determinação da sequência de aminoácidos dos evasins por dedução do cdna dos precursores dessas moléculas expressos em tecidos de serpentes, especificamente bothrops jararaca, processo de amplificação do cdna a partir das bibliotecas de cdna de pâncreas e/ou cérebro de serpentes, especificamente bothrops jararaca; processo de sìntese em fase sólida de peptìdeos inibidores das vasopeptidases com ação vasodilatadora e anti-hipertensiva, peptìdeos inibidores das vasopeptidases com ação anti-hipertensiva; utilização dos peptìdeos inibidores das vaso peptidases com ação vasodilatadora e anti-hipertensiva na obtenção de composições farmacêuticas; processo de determinação da atividade inibitória sobre as vasopeptidases e de atividade biológica sobre músculo liso, sistema cardiovascular e microcirculatório. |
| BRPI0501037B8 (pt) * | 2005-03-18 | 2021-07-27 | Fund De Amparo A Pesquisa Do Estado De Sao Paulo | uso de crotamina e composição |
| US20060234934A1 (en) * | 2005-04-15 | 2006-10-19 | Kilmon Joseph A | Composition and Method for Selective Cytostasis |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5836308B2 (ja) * | 1977-02-10 | 1983-08-08 | 大塚製薬株式会社 | 抗体の製造方法 |
| US4220722A (en) * | 1978-02-10 | 1980-09-02 | Syva Company | Method for conjugating to polyamino compounds employing haloacyl groups and compositions prepared thereby |
| FR2437213A1 (fr) * | 1978-09-28 | 1980-04-25 | Cm Ind | Produits cytotoxiques formes par liaison covalente de la chaine a de la ricine avec un anticorps et leur procede de preparation |
| US4500637A (en) * | 1982-07-19 | 1985-02-19 | The United States Of America As Represented By The Department Of Health And Human Services | Prevention of graft versus host disease following bone marrow transplantation |
-
1985
- 1985-11-22 US US06/801,019 patent/US4731439A/en not_active Expired - Fee Related
-
1986
- 1986-11-19 NL NL8602939A patent/NL8602939A/nl not_active Application Discontinuation
- 1986-11-19 BE BE0/217441A patent/BE905790A/fr not_active IP Right Cessation
- 1986-11-19 FI FI864715A patent/FI864715A7/fi not_active Application Discontinuation
- 1986-11-20 GB GB8627710A patent/GB2185023B/en not_active Expired - Fee Related
- 1986-11-21 ZA ZA868849A patent/ZA868849B/xx unknown
- 1986-11-21 IT IT8622425A patent/IT1207580B/it active
- 1986-11-21 GR GR862788A patent/GR862788B/el unknown
- 1986-11-21 DE DE19863639796 patent/DE3639796A1/de not_active Ceased
- 1986-11-21 ES ES8603138A patent/ES2002915A6/es not_active Expired
- 1986-11-21 DK DK560986A patent/DK560986A/da not_active Application Discontinuation
- 1986-11-21 LU LU86683A patent/LU86683A1/fr unknown
- 1986-11-21 CH CH4672/86A patent/CH670451A5/de not_active IP Right Cessation
- 1986-11-21 FR FR8616270A patent/FR2590576A1/fr not_active Withdrawn
- 1986-11-21 SE SE8604991A patent/SE8604991L/xx not_active Application Discontinuation
- 1986-11-21 AU AU65563/86A patent/AU6556386A/en not_active Abandoned
- 1986-11-21 PT PT83790A patent/PT83790B/pt not_active IP Right Cessation
- 1986-11-21 YU YU01995/86A patent/YU199586A/xx unknown
- 1986-11-22 KR KR1019860009886A patent/KR900006575B1/ko not_active Expired
- 1986-11-22 CN CN198686108593A patent/CN86108593A/zh active Pending
- 1986-11-24 AU AU65609/86A patent/AU6560986A/en not_active Abandoned
-
1990
- 1990-11-16 AU AU66675/90A patent/AU6667590A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| SE8604991D0 (sv) | 1986-11-21 |
| KR900006575B1 (ko) | 1990-09-13 |
| ZA868849B (en) | 1987-07-29 |
| GB8627710D0 (en) | 1986-12-17 |
| FI864715A0 (fi) | 1986-11-19 |
| YU199586A (en) | 1988-06-30 |
| SE8604991L (sv) | 1987-05-23 |
| KR870005014A (ko) | 1987-06-04 |
| GB2185023B (en) | 1990-08-29 |
| CH670451A5 (enrdf_load_stackoverflow) | 1989-06-15 |
| AU6556386A (en) | 1987-05-28 |
| DE3639796A1 (de) | 1987-07-09 |
| PT83790A (en) | 1986-12-01 |
| GB2185023A (en) | 1987-07-08 |
| LU86683A1 (fr) | 1987-06-26 |
| GR862788B (en) | 1987-03-26 |
| BE905790A (fr) | 1987-05-19 |
| AU6667590A (en) | 1991-03-28 |
| US4731439A (en) | 1988-03-15 |
| CN86108593A (zh) | 1987-09-30 |
| PT83790B (pt) | 1989-09-14 |
| FI864715A7 (fi) | 1987-05-23 |
| IT8622425A0 (it) | 1986-11-21 |
| AU6560986A (en) | 1987-05-28 |
| NL8602939A (nl) | 1987-06-16 |
| DK560986D0 (da) | 1986-11-21 |
| DK560986A (da) | 1987-05-23 |
| FR2590576A1 (fr) | 1987-05-29 |
| IT1207580B (it) | 1989-05-25 |
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