ES2001496A6 - Procedimiento de preparacion de derivados de acido cefalosporanico - Google Patents

Procedimiento de preparacion de derivados de acido cefalosporanico

Info

Publication number
ES2001496A6
ES2001496A6 ES8600969A ES8600969A ES2001496A6 ES 2001496 A6 ES2001496 A6 ES 2001496A6 ES 8600969 A ES8600969 A ES 8600969A ES 8600969 A ES8600969 A ES 8600969A ES 2001496 A6 ES2001496 A6 ES 2001496A6
Authority
ES
Spain
Prior art keywords
dethia
preparation
pharmaceutical compositions
therapeutic agents
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600969A
Other languages
English (en)
Inventor
Jean Georges Teutsch
Alain Bonnet
Jozsef Aszodi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES2001496A6 publication Critical patent/ES2001496A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Epoxy Compounds (AREA)

Abstract

EL PROCEDIMIENTO DESCRITO PREPARA COMPUESTOS DE FORMULA: DONDE R Y R1A REPRESENTAN DIVERSOS RADICALES ORGANICOS, R4 REPRESENTA HIDROGENO O METOXI, A REPRESENTA HIDROGENO, UN EQUIVALENTE DE METAL ALCALINO, ALCALINOTERREO, MAGNESIO O AMONIO, UNA BASE ORGANICA AMINADA O UN GRUPO ESTER, O BIEN CO2A REPRESENTA UN GRUPO COC2, Y N2 REPRESENTA 0, 1 O 2, TRATANDO UN PRODUCTO DE FORMULA: DONDE R4 Y A SON COMO ANTES Y RA ES UN RADICAL AMINO O REPRESENTA EL RADICAL R ANTES DEFINIDO, CON UN AGENTE DE HALOGENACION O SULFONACION Y LUEGO CON TRIFENIL FOSFINA O UN REACTIVO DE FORMULA P(OALK(3, DONDE ALK ES ALQUILO, Y SOMETIENDO LOS PRODUCTOS INTERMEDIOS FORMADOS A VARIAS TRANSFORMACIONES DETALLADAS EN LA MEMORIA HASTA LLEGAR AL PRODUCTO FINAL BUSCADO. LOS COMPUESTOS OBTENIDOS Y SUS SALES TIENEN ACTIVIDAD ANTIBIOTICA Y SON UTILES PARA TRATAR AFECCIONES PROVOCADAS POR BACTERIAS GRAM-POSITIVAS Y GRAM-NEGATIVAS.
ES8600969A 1985-08-09 1986-08-08 Procedimiento de preparacion de derivados de acido cefalosporanico Expired ES2001496A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8512218A FR2586020B2 (fr) 1985-08-09 1985-08-09 Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
ES2001496A6 true ES2001496A6 (es) 1988-06-01

Family

ID=9322145

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600969A Expired ES2001496A6 (es) 1985-08-09 1986-08-08 Procedimiento de preparacion de derivados de acido cefalosporanico

Country Status (25)

Country Link
EP (1) EP0214029B1 (es)
JP (1) JPH0667945B2 (es)
KR (1) KR950001028B1 (es)
CN (1) CN1028430C (es)
AT (1) ATE74135T1 (es)
AU (1) AU604641B2 (es)
CA (1) CA1270826A (es)
DE (1) DE3684536D1 (es)
DK (1) DK378986A (es)
ES (1) ES2001496A6 (es)
FI (1) FI86731C (es)
FR (1) FR2586020B2 (es)
GR (1) GR862084B (es)
HU (1) HU204836B (es)
IL (1) IL79493A (es)
MA (1) MA20751A1 (es)
MX (1) MX9326A (es)
NO (1) NO172744C (es)
NZ (1) NZ217167A (es)
OA (1) OA08400A (es)
PT (1) PT83174B (es)
RU (1) RU2042682C1 (es)
SU (1) SU1648252A3 (es)
TN (1) TNSN86120A1 (es)
ZA (1) ZA865910B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2678273B1 (fr) * 1991-06-25 1995-03-03 Roussel Uclaf Nouvelles cephalosporines comportant un noyau 2-thia cepheme, leur procede de preparation, leur application comme medicaments, et les nouveaux intermediaires obtenus.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK194776A (da) * 1975-05-05 1976-11-06 Smithkline Corp Antibakterielle midler og mellemprodukter dertil
DE2716677C2 (de) 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
FR2505840A1 (fr) * 1981-05-13 1982-11-19 Roussel Uclaf Nouveaux produits derives de l'acide 2-amino thiazolyl 2-oxyimino acetamido bicyclo-octene carboxylique, leur procede de preparation et leur application comme medicaments
BE894795A (fr) 1982-10-25 1983-02-14 Plumat Emile Procede de fusion et d'affinage electrique de verre
FR2559486B1 (fr) * 1984-02-13 1988-02-12 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
EP0214029A1 (fr) 1987-03-11
NO172744C (no) 1993-09-01
HU204836B (en) 1992-02-28
FI86731B (fi) 1992-06-30
IL79493A (en) 1993-02-21
KR870002152A (ko) 1987-03-30
JPS6296494A (ja) 1987-05-02
PT83174A (fr) 1986-09-01
SU1648252A3 (ru) 1991-05-07
EP0214029B1 (fr) 1992-03-25
FR2586020A2 (fr) 1987-02-13
FI863247A0 (fi) 1986-08-08
NO862986D0 (no) 1986-07-24
KR950001028B1 (ko) 1995-02-07
MX9326A (es) 1993-11-01
CN1028430C (zh) 1995-05-17
GR862084B (en) 1986-12-24
CN86105905A (zh) 1987-07-29
ATE74135T1 (de) 1992-04-15
NO862986L (no) 1987-02-10
FI863247A (fi) 1987-02-10
ZA865910B (en) 1987-10-28
PT83174B (pt) 1988-07-29
RU2042682C1 (ru) 1995-08-27
DE3684536D1 (de) 1992-04-30
OA08400A (fr) 1988-06-30
NO172744B (no) 1993-05-24
DK378986A (da) 1987-02-10
JPH0667945B2 (ja) 1994-08-31
MA20751A1 (fr) 1987-04-01
TNSN86120A1 (fr) 1990-01-01
HUT44559A (en) 1988-03-28
AU604641B2 (en) 1991-01-03
DK378986D0 (da) 1986-08-08
CA1270826A (fr) 1990-06-26
IL79493A0 (en) 1986-10-31
FR2586020B2 (fr) 1988-10-14
NZ217167A (en) 1989-05-29
AU6101686A (en) 1987-02-12
FI86731C (fi) 1992-10-12

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