ZA865910B - Derivatives of 1-dethia 2-thiacephalosporanic acid,their process for preparing,their application as medicaments and the pharmaceutical compositions containing them - Google Patents

Derivatives of 1-dethia 2-thiacephalosporanic acid,their process for preparing,their application as medicaments and the pharmaceutical compositions containing them

Info

Publication number
ZA865910B
ZA865910B ZA865910A ZA865910A ZA865910B ZA 865910 B ZA865910 B ZA 865910B ZA 865910 A ZA865910 A ZA 865910A ZA 865910 A ZA865910 A ZA 865910A ZA 865910 B ZA865910 B ZA 865910B
Authority
ZA
South Africa
Prior art keywords
derivatives
thiacephalosporanic
dethia
medicaments
preparing
Prior art date
Application number
ZA865910A
Inventor
Jean Georges Teutsch
Alain Bonnet
Jozsef Aszodi
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA865910B publication Critical patent/ZA865910B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Epoxy Compounds (AREA)

Abstract

The derivatives in question are the products of formula I <IMAGE> R = either <IMAGE> Ra = an organic group; <IMAGE> R'A and R'B are either a hydrogen atom or an alkyl radical; ZA = single bond, sulphur, optionally oxidised, or oxygen, R3A = in particular, aryl, optionally substituted, quaternary ammonium, acetyl, carbamoyl, alkoxycarbonyl, alkyl, haloalkyl, nitrile or azido; R4 = H or OCH3; A = in particular, H, alkali metal equivalent, ester or CO2A; CO2<(-)>; n2 = integer equal to 0, 1 or 2; and the salts of the products of formula IA with inorganic or organic acids.
ZA865910A 1985-08-09 1986-08-06 Derivatives of 1-dethia 2-thiacephalosporanic acid,their process for preparing,their application as medicaments and the pharmaceutical compositions containing them ZA865910B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8512218A FR2586020B2 (en) 1985-08-09 1985-08-09 NOVEL DERIVATIVES OF 1-DETHIA 2-THIA CEPHALOSPORANIC ACID, PROCESS FOR THEIR PREPARATION, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (1)

Publication Number Publication Date
ZA865910B true ZA865910B (en) 1987-10-28

Family

ID=9322145

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA865910A ZA865910B (en) 1985-08-09 1986-08-06 Derivatives of 1-dethia 2-thiacephalosporanic acid,their process for preparing,their application as medicaments and the pharmaceutical compositions containing them

Country Status (25)

Country Link
EP (1) EP0214029B1 (en)
JP (1) JPH0667945B2 (en)
KR (1) KR950001028B1 (en)
CN (1) CN1028430C (en)
AT (1) ATE74135T1 (en)
AU (1) AU604641B2 (en)
CA (1) CA1270826A (en)
DE (1) DE3684536D1 (en)
DK (1) DK378986A (en)
ES (1) ES2001496A6 (en)
FI (1) FI86731C (en)
FR (1) FR2586020B2 (en)
GR (1) GR862084B (en)
HU (1) HU204836B (en)
IL (1) IL79493A (en)
MA (1) MA20751A1 (en)
MX (1) MX9326A (en)
NO (1) NO172744C (en)
NZ (1) NZ217167A (en)
OA (1) OA08400A (en)
PT (1) PT83174B (en)
RU (1) RU2042682C1 (en)
SU (1) SU1648252A3 (en)
TN (1) TNSN86120A1 (en)
ZA (1) ZA865910B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2678273B1 (en) * 1991-06-25 1995-03-03 Roussel Uclaf NOVEL CEPHALOSPORINS COMPRISING A 2-THIA CEPHEME CORE, THEIR PREPARATION PROCESS, THEIR APPLICATION AS MEDICAMENTS, AND THE NEW INTERMEDIATES OBTAINED.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK194776A (en) * 1975-05-05 1976-11-06 Smithkline Corp ANTIBACTERIAL MEDICINES AND INTERMEDIATE PRODUCTS THEREOF
DE2716677C2 (en) 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephem derivatives and processes for their preparation
FR2505840A1 (en) * 1981-05-13 1982-11-19 Roussel Uclaf NOVEL PRODUCTS DERIVED FROM 2-AMINO THIAZOLYL 2-OXYIMINO ACETAMIDO BICYCLO-OCTENE CARBOXYLIC ACID, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS
BE894795A (en) 1982-10-25 1983-02-14 Plumat Emile Electric melting and refining furnace for glass - where batch flows vertically downwards through melting, refining and conditioning zones
FR2559486B1 (en) * 1984-02-13 1988-02-12 Roussel Uclaf NOVEL DERIVATIVES OF 1-DETHIA 2-THIA CEPHALOSPORANIC ACID, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS

Also Published As

Publication number Publication date
EP0214029A1 (en) 1987-03-11
NO172744C (en) 1993-09-01
ES2001496A6 (en) 1988-06-01
HU204836B (en) 1992-02-28
FI86731B (en) 1992-06-30
IL79493A (en) 1993-02-21
KR870002152A (en) 1987-03-30
JPS6296494A (en) 1987-05-02
PT83174A (en) 1986-09-01
SU1648252A3 (en) 1991-05-07
EP0214029B1 (en) 1992-03-25
FR2586020A2 (en) 1987-02-13
FI863247A0 (en) 1986-08-08
NO862986D0 (en) 1986-07-24
KR950001028B1 (en) 1995-02-07
MX9326A (en) 1993-11-01
CN1028430C (en) 1995-05-17
GR862084B (en) 1986-12-24
CN86105905A (en) 1987-07-29
ATE74135T1 (en) 1992-04-15
NO862986L (en) 1987-02-10
FI863247A (en) 1987-02-10
PT83174B (en) 1988-07-29
RU2042682C1 (en) 1995-08-27
DE3684536D1 (en) 1992-04-30
OA08400A (en) 1988-06-30
NO172744B (en) 1993-05-24
DK378986A (en) 1987-02-10
JPH0667945B2 (en) 1994-08-31
MA20751A1 (en) 1987-04-01
TNSN86120A1 (en) 1990-01-01
HUT44559A (en) 1988-03-28
AU604641B2 (en) 1991-01-03
DK378986D0 (en) 1986-08-08
CA1270826A (en) 1990-06-26
IL79493A0 (en) 1986-10-31
FR2586020B2 (en) 1988-10-14
NZ217167A (en) 1989-05-29
AU6101686A (en) 1987-02-12
FI86731C (en) 1992-10-12

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