ES2000502A6 - Un procedimiento para la preparacion de poli-4-aminopirrol-2-carboxamido derivados - Google Patents
Un procedimiento para la preparacion de poli-4-aminopirrol-2-carboxamido derivadosInfo
- Publication number
- ES2000502A6 ES2000502A6 ES8600290A ES8600290A ES2000502A6 ES 2000502 A6 ES2000502 A6 ES 2000502A6 ES 8600290 A ES8600290 A ES 8600290A ES 8600290 A ES8600290 A ES 8600290A ES 2000502 A6 ES2000502 A6 ES 2000502A6
- Authority
- ES
- Spain
- Prior art keywords
- reaction
- procedure
- preparation
- organic solvent
- carboxamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 4
- 239000003960 organic solvent Substances 0.000 abstract 3
- 229940053202 antiepileptics carboxamide derivative Drugs 0.000 abstract 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Polyamides (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858517922A GB8517922D0 (en) | 1985-07-16 | 1985-07-16 | Carboxamido derivatives |
| GB868613594A GB8613594D0 (en) | 1986-06-04 | 1986-06-04 | Poly-4-aminopyrrole-2-carboxamido derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2000502A6 true ES2000502A6 (es) | 1988-03-01 |
Family
ID=26289538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8600290A Expired ES2000502A6 (es) | 1985-07-16 | 1986-07-14 | Un procedimiento para la preparacion de poli-4-aminopirrol-2-carboxamido derivados |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPH0780843B2 (enExample) |
| KR (1) | KR930010496B1 (enExample) |
| CN (1) | CN1018825B (enExample) |
| AT (1) | AT387013B (enExample) |
| AU (1) | AU587841B2 (enExample) |
| BE (1) | BE905110A (enExample) |
| CA (1) | CA1285934C (enExample) |
| CH (1) | CH674206A5 (enExample) |
| CS (1) | CS276981B6 (enExample) |
| DE (1) | DE3623880A1 (enExample) |
| DK (1) | DK335986A (enExample) |
| ES (1) | ES2000502A6 (enExample) |
| FI (1) | FI83640C (enExample) |
| FR (1) | FR2585018B1 (enExample) |
| GB (1) | GB2178036B (enExample) |
| GR (1) | GR861841B (enExample) |
| HU (1) | HU205949B (enExample) |
| IE (1) | IE59073B1 (enExample) |
| IL (1) | IL79402A (enExample) |
| IT (1) | IT1196488B (enExample) |
| NL (1) | NL8601837A (enExample) |
| NO (1) | NO168826C (enExample) |
| NZ (1) | NZ216829A (enExample) |
| PH (1) | PH24714A (enExample) |
| PT (1) | PT82984B (enExample) |
| SE (1) | SE468642B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN85103908A (zh) * | 1985-07-16 | 1986-11-05 | 法米塔利·卡洛·埃尔巴有限公司 | 制备4′-表多克索红菌素的新方法 |
| GB8906709D0 (en) * | 1989-03-23 | 1989-05-10 | Creighton Andrew M | Acryloyl substituted pyrrole derivatives |
| IT1243389B (it) * | 1990-11-22 | 1994-06-10 | Menarini Farma Ind | Derivati poliaminopirrolcarbossiamidici, processi di preparazione e composizioni farmaceutiche che li contengono. |
| WO1992013838A1 (en) * | 1991-02-06 | 1992-08-20 | Synphar Laboratories, Inc. | Oligopeptide antiretroviral agents |
| IT1247878B (it) * | 1991-02-15 | 1995-01-05 | Menarini Farma Ind | Derivati poli-4-aminopirrol-2-carbossiamidici,processi di preparazione e composizioni farmaceutiche che li contengono |
| GB2260134A (en) * | 1991-10-04 | 1993-04-07 | Erba Carlo Spa | Derivatives of poly-5-amino-3-carboxy-1-methyl compounds |
| IT1262921B (it) * | 1992-01-10 | 1996-07-22 | Federico Arcamone | Agenti antitumorali analoghi di oligopeptidi pirrol-amidinici retroversi processi di preparazione e prodotti farmaceutici che li contengono |
| GB9416005D0 (en) * | 1994-08-08 | 1994-09-28 | Erba Carlo Spa | Peptidic compounds analogous to distamycin a and process for their preparation |
| CA2204648A1 (en) * | 1995-09-12 | 1997-03-20 | Akira Mihara | Uch15 compounds |
| AU1596097A (en) * | 1996-02-02 | 1997-08-22 | Pharmacia & Upjohn S.P.A. | Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
| GB9615692D0 (en) * | 1996-07-25 | 1996-09-04 | Pharmacia Spa | Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
| GB0011059D0 (en) | 2000-05-08 | 2000-06-28 | Pharmacia & Upjohn Spa | Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione |
| GB0015447D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
| GB0015446D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
| GB0016447D0 (en) | 2000-07-04 | 2000-08-23 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
| US6969592B2 (en) | 2001-09-26 | 2005-11-29 | Pharmacia Italia S.P.A. | Method for predicting the sensitivity to chemotherapy |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR86210E (enExample) * | 1963-04-04 | 1966-03-23 | ||
| US3420844A (en) * | 1963-07-26 | 1969-01-07 | Farmaceutici Italia | Pyrrole-2-carboxamido-propionamidines |
| DE1795539A1 (de) * | 1963-07-26 | 1972-01-13 | Farmaceutici Italia | Verfahren zur Herstellung von neuen Pyrrolderivaten und ihren Salzen |
| BE666612A (enExample) * | 1963-07-26 | 1965-11-03 | ||
| NL130086C (enExample) * | 1964-07-14 | 1970-06-15 | ||
| CN85103908A (zh) * | 1985-07-16 | 1986-11-05 | 法米塔利·卡洛·埃尔巴有限公司 | 制备4′-表多克索红菌素的新方法 |
-
1986
- 1986-07-11 AT AT0188886A patent/AT387013B/de not_active IP Right Cessation
- 1986-07-11 SE SE8603098A patent/SE468642B/sv not_active IP Right Cessation
- 1986-07-14 HU HU862904A patent/HU205949B/hu not_active IP Right Cessation
- 1986-07-14 ES ES8600290A patent/ES2000502A6/es not_active Expired
- 1986-07-14 NL NL8601837A patent/NL8601837A/xx not_active Application Discontinuation
- 1986-07-14 IL IL79402A patent/IL79402A/xx not_active IP Right Cessation
- 1986-07-14 AU AU60202/86A patent/AU587841B2/en not_active Ceased
- 1986-07-14 NZ NZ216829A patent/NZ216829A/xx unknown
- 1986-07-14 IE IE187586A patent/IE59073B1/en not_active IP Right Cessation
- 1986-07-15 IT IT21125/86A patent/IT1196488B/it active
- 1986-07-15 CA CA000513760A patent/CA1285934C/en not_active Expired - Lifetime
- 1986-07-15 DE DE3623880A patent/DE3623880A1/de not_active Withdrawn
- 1986-07-15 PT PT82984A patent/PT82984B/pt not_active IP Right Cessation
- 1986-07-15 JP JP61164879A patent/JPH0780843B2/ja not_active Expired - Lifetime
- 1986-07-15 KR KR1019860005715A patent/KR930010496B1/ko not_active Expired - Fee Related
- 1986-07-15 CH CH2820/86A patent/CH674206A5/de not_active IP Right Cessation
- 1986-07-15 BE BE0/216924A patent/BE905110A/fr not_active IP Right Cessation
- 1986-07-15 PH PH34014A patent/PH24714A/en unknown
- 1986-07-15 DK DK335986A patent/DK335986A/da not_active Application Discontinuation
- 1986-07-15 GR GR861841A patent/GR861841B/el unknown
- 1986-07-15 NO NO862860A patent/NO168826C/no unknown
- 1986-07-15 FR FR868610294A patent/FR2585018B1/fr not_active Expired
- 1986-07-16 GB GB8617292A patent/GB2178036B/en not_active Expired
- 1986-07-16 CN CN86104787A patent/CN1018825B/zh not_active Expired
- 1986-07-16 FI FI862959A patent/FI83640C/fi not_active IP Right Cessation
- 1986-07-16 CS CS865412A patent/CS276981B6/cs unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1A | Transfer granted |