ES179385A1 - A PROCEDURE FOR THE PREPARATION OF SUCCINYLSULFATIAZOLE - Google Patents

A PROCEDURE FOR THE PREPARATION OF SUCCINYLSULFATIAZOLE

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Publication number
ES179385A1
ES179385A1 ES0179385A ES179385A ES179385A1 ES 179385 A1 ES179385 A1 ES 179385A1 ES 0179385 A ES0179385 A ES 0179385A ES 179385 A ES179385 A ES 179385A ES 179385 A1 ES179385 A1 ES 179385A1
Authority
ES
Spain
Prior art keywords
succinic acid
final product
preparation
monochloride
desired final
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0179385A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sharp and Dohme Inc
Original Assignee
Sharp and Dohme Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sharp and Dohme Inc filed Critical Sharp and Dohme Inc
Priority to ES0179385A priority Critical patent/ES179385A1/en
Publication of ES179385A1 publication Critical patent/ES179385A1/en
Expired legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un procedimiento para la preparación de succinilsulfatiazola caracterizada por tener la fórmula de estructura **(Ver fórmula)** y sus compuestosque consiste esencialmente en calentar ácido succínicoanhídrido de ácido succínico o un monohaluro tal como un monocloruro del éste alkilo de ácido succínicocomo: **(Ver fórmula)** con sulfatiazolaesto es 2-(p-aminobencenosulfamido)-tiazolatanto cuando meramente se emplea ácido succínicocomo cuando en un medio inerte de reacción tal como un disolvente inerte se usa anhídrido succínicoen el último caso separando el deseado producto finaly en el caso de usar el monocloruro del éster liberando el deseado producto final por hidrolisis y en algunos casossi es necesario sometiendo el producto final a purificación por recristalización.A process for the preparation of succinylsulfathiazole characterized by having the structure formula ** (See formula) ** and its compounds which essentially consists of heating succinic acid anhydride of succinic acid or a monohalide such as a monochloride of this alkyl of succinic acid as: ** (See formula) ** with sulfathiazola this is 2- (p-aminobenzenesulfamido) -thiazola both when merely succinic acid is used and when in an inert reaction medium such as an inert solvent succinic anhydride is used in the latter case separating the desired final product and in the case of using the monochloride of the ester releasing the desired final product by hydrolysis and in some cases if necessary subjecting the final product to purification by recrystallization.

ES0179385A 1947-08-07 1947-08-07 A PROCEDURE FOR THE PREPARATION OF SUCCINYLSULFATIAZOLE Expired ES179385A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES0179385A ES179385A1 (en) 1947-08-07 1947-08-07 A PROCEDURE FOR THE PREPARATION OF SUCCINYLSULFATIAZOLE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES0179385A ES179385A1 (en) 1947-08-07 1947-08-07 A PROCEDURE FOR THE PREPARATION OF SUCCINYLSULFATIAZOLE

Publications (1)

Publication Number Publication Date
ES179385A1 true ES179385A1 (en) 1948-05-16

Family

ID=37821958

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0179385A Expired ES179385A1 (en) 1947-08-07 1947-08-07 A PROCEDURE FOR THE PREPARATION OF SUCCINYLSULFATIAZOLE

Country Status (1)

Country Link
ES (1) ES179385A1 (en)

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