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Sharp and Dohme Inc
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Sharp and Dohme Inc
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Publication of ES179384A1publicationCriticalpatent/ES179384A1/en
Un procedimiento para la preparación de ftalilsulfatiazola del tipo 2-N4-ftalilsulfanilamidotiazolaque consiste esencialmente en calentar ácido ftálicoanhídrido de ácido ftálicoo un monohaluro tal como el monocloruro del éster alkilo del ácido ftálico tal como: **(Ver fórmula)** con sulfatiazolaesto es 2-(p-aminobencenosulfamido)-tiazolatanto cuando meramente se emplea el ácido ftálico como en un medio inerte de reacción tal como un disolvente inertecomo cuando se usa anhídrido ftálicoy en este último caso separando el deseado producto final: y en el caso de usar el monocloruro del éster liberando dicho producto final de hidrolisis y en algún casoes necesariosujetando el producto final a purificación por recristalización.A process for the preparation of phthalylsulfathiazole of the type 2-N4-phthalylsulfanylamidothiazole which consists essentially in heating phthalic acid anhydride of phthalic acid or a monohalide such as the monochloride of the alkyl ester of phthalic acid such as: ** (See formula) ** with sulfathiazole is 2 - (p-aminobenzenesulfamido) -thiazolate both when merely using phthalic acid and in an inert reaction medium such as an inert solvent as when using phthalic anhydride and in the latter case separating the desired final product: and in the case of using monochloride of the ester releasing said final hydrolysis product and in some cases it is necessary subjecting the final product to purification by recrystallization.
ES0179384A1943-04-171947-08-07
A PROCEDURE FOR THE PREPARATION OF FTHALYLSULFATIAZOLE
ExpiredES179384A1
(en)
Process for the sulfonation of fatty acids and their esters, resulting products and their applications as detersing, foaming, wetting, dispersing and humectant agents
A PROCEDURE FOR THE PREPARATION OF PURIFIED ALCOHILOI-OR ALCENYLOXINI TROANILINS WHICH HAVE BEEN PRODUCED BY PARTIAL REDUCTION OF 1,5-DINITROBENZENES SUBSTITUTED IN POSITION 2 AND EVENTUAL TRANSFORMATION OF ALCOHYL 2-SUBSTITUTE GROUP