EP4140992A4 - Verfahren zur herstellung von s-nikotin - Google Patents

Verfahren zur herstellung von s-nikotin Download PDF

Info

Publication number
EP4140992A4
EP4140992A4 EP21810886.8A EP21810886A EP4140992A4 EP 4140992 A4 EP4140992 A4 EP 4140992A4 EP 21810886 A EP21810886 A EP 21810886A EP 4140992 A4 EP4140992 A4 EP 4140992A4
Authority
EP
European Patent Office
Prior art keywords
nicotine
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21810886.8A
Other languages
English (en)
French (fr)
Other versions
EP4140992A1 (de
Inventor
Jun Zou
Yang Zou
Meisen LIU
Weixian LUO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Zinwi Biotech Co Ltd
Original Assignee
Shenzhen Zinwi Biotech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Zinwi Biotech Co Ltd filed Critical Shenzhen Zinwi Biotech Co Ltd
Publication of EP4140992A1 publication Critical patent/EP4140992A1/de
Publication of EP4140992A4 publication Critical patent/EP4140992A4/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/12—Chemical features of tobacco products or tobacco substitutes of reconstituted tobacco
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EP21810886.8A 2021-07-10 2021-08-16 Verfahren zur herstellung von s-nikotin Pending EP4140992A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202110781163.8A CN113475739B (zh) 2021-07-10 2021-07-10 一种s-尼古丁的制备方法
PCT/CN2021/112793 WO2023284057A1 (zh) 2021-07-10 2021-08-16 一种s-尼古丁的制备方法

Publications (2)

Publication Number Publication Date
EP4140992A1 EP4140992A1 (de) 2023-03-01
EP4140992A4 true EP4140992A4 (de) 2023-12-06

Family

ID=77938477

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21810886.8A Pending EP4140992A4 (de) 2021-07-10 2021-08-16 Verfahren zur herstellung von s-nikotin

Country Status (3)

Country Link
EP (1) EP4140992A4 (de)
CN (1) CN113475739B (de)
WO (1) WO2023284057A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114276204B (zh) * 2021-12-24 2024-02-27 大庆雾泰化工科技有限公司 一种(s)-(-)-尼古丁的制备方法
CN114437031B (zh) * 2022-02-16 2023-06-27 深圳市真味生物科技有限公司 一种6-甲基尼古丁的合成方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3925955A1 (de) * 2020-04-22 2021-12-22 Shenzhen Catalys Technology Co., Ltd. Verfahren zur asymmetrischen herstellung von nikotin

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US5187280A (en) * 1990-09-20 1993-02-16 Warner-Lambert Company Substituted tetrahydropyridines and their use as central nervous system agents
US5045550A (en) * 1990-09-20 1991-09-03 Warner-Lambert Co. Substituted tetrahydropyridines as central nervous system agents
US5648541A (en) * 1995-09-28 1997-07-15 Nps Pharmaceuticals, Inc. Chiral reductions of imines leading to the syntheses of optically active amines
JPH11312351A (ja) 1998-04-28 1999-11-09 Sony Corp ディスクローディング装置
CN1106892C (zh) * 2000-10-16 2003-04-30 云南万芳生物技术有限公司 提取烟草净油、类黑素、烟碱及制备复合肥的方法
US20030224435A1 (en) * 2002-05-16 2003-12-04 Scott Seiwert Detection of abused substances and their metabolites using nucleic acid sensor molecules
US8367837B2 (en) * 2011-02-14 2013-02-05 Divi's Laboratories, Ltd. Process for the preparation of (R,S)-nicotine
CN104341390B (zh) 2014-11-04 2016-09-07 南开大学 一种植物源农药烟碱和毒藜碱的不对称合成方法
US9809567B2 (en) * 2014-12-09 2017-11-07 Njoy, Llc Synthesis and resolution of nicotine
CN107011321A (zh) * 2017-03-27 2017-08-04 华健 一种人工合成消旋体尼古丁的制备方法
CN107382916A (zh) * 2017-08-30 2017-11-24 成都化润药业有限公司 3‑四氢呋喃甲醇的高纯度合成方法
HUE057748T2 (hu) * 2017-12-22 2022-06-28 Siegfried Ag Egyedényes eljárás racém nikotin elõállítására, etil-nikotinát vinilpirrolidonnal végzett reakciójával, nátrium-etanolát vagy kálium-etanolát vagy ezek keverékeinek jelenlétében
CN110256403B (zh) * 2019-07-02 2020-06-19 深圳市馨艺坊生物科技有限公司 一种人工合成尼古丁的制备方法
CN110357853B (zh) * 2019-08-05 2020-07-10 济南悟通生物科技有限公司 (r,s-)尼古丁的合成方法
CN110627769A (zh) * 2019-09-27 2019-12-31 深圳黑尔格科技有限公司 亚胺盐衍生物、其制备方法及尼古丁的制备方法
CN111004212A (zh) * 2019-12-24 2020-04-14 深圳雾芯科技有限公司 一种制备尼古丁的方法
CN111233829A (zh) * 2019-12-27 2020-06-05 深圳黑尔格科技有限公司 一种具有光学活性的尼古丁的制备方法
KR102653443B1 (ko) * 2020-03-25 2024-03-29 선전 필라이프 라이프 사이언스 컴퍼니., 리미티드. 인공 합성 라세미 니코틴 염의 제조 방법
CN112409327A (zh) * 2020-11-18 2021-02-26 山东金城医药化工有限公司 一种高光学纯度烟碱的制备方法
CN112409329A (zh) * 2020-12-11 2021-02-26 山东金城医药化工有限公司 S-尼古丁的制备方法
CN112745294B (zh) * 2020-12-30 2022-02-22 山东金城柯瑞化学有限公司 (r,s-)尼古丁的合成方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3925955A1 (de) * 2020-04-22 2021-12-22 Shenzhen Catalys Technology Co., Ltd. Verfahren zur asymmetrischen herstellung von nikotin

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HUANG KUN ET AL: "A new and efficient approach to the synthesis of nicotine and anabasine analogues", JOURNAL OF HETEROCYCLIC CHEMISTRY, vol. 46, no. 6, 1 November 2009 (2009-11-01), US, pages 1252 - 1258, XP093022372, ISSN: 0022-152X, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811585/pdf/nihms168667.pdf> DOI: 10.1002/jhet.233 *
See also references of WO2023284057A1 *

Also Published As

Publication number Publication date
WO2023284057A1 (zh) 2023-01-19
CN113475739A (zh) 2021-10-08
EP4140992A1 (de) 2023-03-01
CN113475739B (zh) 2022-11-11

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