EP3454818B1 - Adaptateur - Google Patents

Adaptateur Download PDF

Info

Publication number
EP3454818B1
EP3454818B1 EP17721142.2A EP17721142A EP3454818B1 EP 3454818 B1 EP3454818 B1 EP 3454818B1 EP 17721142 A EP17721142 A EP 17721142A EP 3454818 B1 EP3454818 B1 EP 3454818B1
Authority
EP
European Patent Office
Prior art keywords
insert
adapter
wall
outer body
circumferential wall
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP17721142.2A
Other languages
German (de)
English (en)
Other versions
EP3454818A1 (fr
Inventor
Peter Henninger
Markus Kehr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SFM Medical Devices GmbH
Original Assignee
SFM Medical Devices GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SFM Medical Devices GmbH filed Critical SFM Medical Devices GmbH
Publication of EP3454818A1 publication Critical patent/EP3454818A1/fr
Application granted granted Critical
Publication of EP3454818B1 publication Critical patent/EP3454818B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2055—Connecting means having gripping means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2079—Filtering means
    • A61J1/2086—Filtering means for fluid filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • B65D81/3205—Separate rigid or semi-rigid containers joined to each other at their external surfaces
    • B65D81/3211—Separate rigid or semi-rigid containers joined to each other at their external surfaces coaxially and provided with means facilitating admixture

Definitions

  • the invention relates to an adapter for transferring a substance from a first container to a second container, such as a syringe body, comprising a circumferential wall suitable for receiving the first container, along which and coaxially surrounded by this at least in sections, a cannula body runs, as well as one with the Hollow cylindrical section connected to the cannula body, which can be connected to the second container, the cannula body extending with its longitudinal axis perpendicular to one side of a wall running transversely to the peripheral wall and the hollow cylindrical section extending with its longitudinal axis perpendicular to the other side of the wall.
  • the U.S. 6,558,365 A a device for mixing fluids present in containers is shown, which consists of two adapters that are connected to one another in the manner of a screw connection via Luer lock cones. There is also the possibility of connecting the adapter, which has a female Luer lock cone, to a syringe body.
  • a transfer device for removing or transferring a fluid which consists of a first and a transfer device in The longitudinal axis is displaceable second part. In order to enable the parts to be moved relative to one another, one of the parts must enclose the opening area of a container.
  • Subject of WO 2017/140238 A2 is a transfer device with a first and a second adapter part, which are axially displaceable to one another.
  • a first inner adapter part receives a vial which has a closure and which can be penetrated by a spike extending from the outer, second adapter part.
  • the spike is based on a bottom wall running transversely to the peripheral wall. The spike extends into a hollow cylindrical section protruding from the opposite side of the wall.
  • a closed vial is received by a first adapter part, onto which a second adapter part can be clamped, which has a spike on the one hand and a Luer lock cone on the other hand, which extend from opposite sides of a disk-shaped plate element.
  • a spike on the one hand and a Luer lock cone on the other originate from an outer adapter part ( US 2014/0000738 A1 ).
  • the WO 2011/029184 A1 an adapter with an outer and an inner body can be seen from which on the one hand a cannula and on the other hand a Luer lock cone extend.
  • the inner body has fingers which, on the one hand, receive a plate element protecting the cannula when not in use and, on the other hand, engage behind the neck of a vial after the plate has been deposited.
  • the object of the present invention is to further develop an adapter of the type mentioned at the outset in such a way that it is easy to handle, offers sufficient stability and, in particular, prevents the adapter from being grasped externally the receptacle received by this - also called the vial - is unintentionally changed in position. If necessary, it should also be possible to adapt to containers of different sizes with simple measures.
  • the adapter according to claim 1 has a pot-shaped outer body with an outer peripheral wall and the wall that runs transversely to the longitudinal axis of the outer body, that the pot-shaped outer body has an insert with the peripheral wall that receives the container comprises, and that the outer body and the insert are one unit and immovable to one another in the longitudinal axis direction of the adapter.
  • Cup-shaped means that the outer body basically has a hollow cylinder geometry on the circumferential side, even if the outer body can also have a geometry that deviates from this on the outside.
  • the term cup-shaped outer body also includes one whose outer geometry z. B. that of a polygonal column such as a parallelepiped shape.
  • cup-shaped is to be understood as a synonym.
  • a cup-shaped outer body should, however, in particular convey that the outer body has a cylindrical geometry on the inside.
  • the outer body should also be free of slots on the circumferential side, ie, in deviation from the prior art, there are no slots running in the longitudinal axis direction of the adapter starting from the front edge in order to achieve flexibility.
  • the outer body can be described as closed on the circumference.
  • a separate receptacle forming an insert is provided for the container (vial), which is located within the pot-shaped or hollow-body-shaped outer body, which can be referred to as a housing, so that it can consist of a relatively rigid material, in particular plastic material that retains its geometry when capturing the outer body.
  • the adapter has sections separated by slots on the circumference in order to receive a vial, so that the adapter parts are flexible on the circumference.
  • the outer body and insert form a unit.
  • the outer body and insert cannot be moved in the longitudinal direction with respect to one another.
  • the outer body and the insert are connected to one another, in particular in a materially bonded manner.
  • the unit thus formed is pushed onto a vial or the vial is introduced into the unit. There is no relative displacement in the direction of the longitudinal axis between the outer body and the insert.
  • the insert which is connected to the outer body and forms a unit therewith, is provided for receiving the vial results in a modular one Structure with the result that without changing the geometry of the outer part, i.e. the cup-shaped outer body, inserts of different cross-sections can be introduced in order to be adapted to vials of different dimensions, so that they can be fixed to the required extent.
  • the outer body and the insert are of course connected to one another, in particular in a materially bonded manner, even if, for example, a latching connection or other connection is also possible.
  • the pot-shaped or hollow body-shaped outer body of the adapter forms a housing which, at least in sections, can have a cylindrical geometry on the outside.
  • a filter element can be positioned and fixed without problems.
  • This can previously be connected, such as welded, to the outer surface of the bottom wall of the insert in order to then materially connect the insert to the wall of the pot-shaped or hollow body-shaped outer body, in particular by means of ultrasonic welding, in such a way that the bottom wall is connected to the wall in a liquid-tight manner.
  • This ensures that when the adapter is connected to the second container, in particular the syringe body, the liquid flowing through the hollow cylindrical section, in particular designed as a Luer cone, can flow exclusively via the filter from a vial into the second container.
  • a filter If a filter is available, it should be designed as a surface filter.
  • the filter fabric is placed between two surfaces.
  • the entire surface along which the filter fabric extends can be provided with regular, centrally extending depressions.
  • the supply and discharge of the liquid is preferably carried out via four symmetrically arranged, centrally running channels which lead the liquid to a central depression.
  • the projections in the surface serve as a support for the fabric and thus as a support surface.
  • the female Luer cone makes it easy to remove the prepared medication without the need for a metal cannula. This enables needle-free removal.
  • the circumferential wall of the insert which is surrounded in particular concentrically by the outer circumferential wall of the outer body such as the housing, has projections extending radially into the interior of the insert for holding the container, the circumferential wall being at least in the area of the projections at a distance from Inside of the outer peripheral wall runs.
  • the peripheral wall is preferably completely covered by the outer peripheral wall, but at least in the area of the projections.
  • the projections serve in particular to grip behind a bead-like edge of the vial. So that the elastically bendable projections, which extend from wall sections of the peripheral wall, can be adjusted to the required extent, the peripheral wall is spaced apart from the outer peripheral wall at least in the area of the projections. In particular, it is provided that the circumferential wall extends at a distance from the outer circumferential wall overall.
  • the z. B. formed as a Luer cone hollow cylindrical section from the wall of the housing.
  • the hollow needle body which is preferably designed as a plastic spike and can also be referred to as a cannula body, extends in the opposite direction to the hollow cylindrical section from the bottom wall into the interior of the insert accommodated by the housing.
  • the cannula body or spike extends from the bottom wall of the insert, it is possible to place a filter between the insert and the housing without problems.
  • the outside bottom surface of the insert, along which the filter extends, should be structured so that the filter element does not come into contact with one another.
  • the insert comprises a cylindrical first section running at the bottom and a second section with a larger outer diameter that extends over a step and forms the peripheral wall.
  • the insert is circumferentially connected to the hollow-body-shaped outer body in a liquid-tight manner, in particular there is a material connection which can be produced by means of ultrasonic welding.
  • cup-shaped outer body and the insert present in it are designed in particular as injection molded parts.
  • an adapter 14 is shown in principle.
  • the adapter 14 is used to receive a container or bottle, which is also referred to as a vial 10. Furthermore, the adapter 14 is to be connected to a second container, in particular a syringe body 12, in order to withdraw a medical substance from the vial 10 received by the adapter 14.
  • the adapter 14 has a pot-shaped outer body 18, to be referred to as a housing, which consists of an outer circumferential wall 32 having a hollow cylinder geometry and a wall 24 delimiting this at the end.
  • the outer peripheral wall 32 is closed on the periphery and consists in particular of a dimensionally stable plastic.
  • the invention is not abandoned if the outer geometry of the peripheral wall 32 deviates from a cylinder geometry.
  • the inner geometry of the outer body 18 should have a cylindrical shape.
  • the wall 24 which is also referred to below as the end wall, merges via a step 24 into a radially projecting edge 25 which forms a flange and projects from the peripheral wall 32.
  • the edge 25 is flattened on diametrically opposite sides, as can be seen from the drawings. This is a problem-free detection of the housing, that is to say of the outer body 18, is possible. At the same time, there is roll protection.
  • an insert 46 is introduced into the outer body 18, which is in particular materially connected to the end wall 24 and preferably all the way around it.
  • the insert 46 has a circumferential wall 47 which runs coaxially to the outer circumferential wall 32 and which consequently runs concentrically around the longitudinal axis of the outer body 18 and thus of the adapter 14.
  • the longitudinal axis is illustrated by the dot-dash line 27.
  • the insert 46 serves as a receptacle or holder for the vial 10 to be fixed.
  • projections 48, 50, 52 which extend into the interior of the insert 46 and have a hook-shaped geometry, ie in section, protrude from the peripheral wall 47 of the insert 46 May have triangular geometry in order, after the vial 10 has been properly introduced, to grip behind its bead-like edge and thus ensure fixing.
  • the insert 46 i.e. its circumferential wall 47 at least in the area of the projections 48, 50, 52, but preferably over the entire circumference, at a distance from the inside of the outer peripheral wall 32 of the outer body 18. Furthermore, recesses 49, 51, 53 are provided, which between the projections 48, 50, 52 and the extend along the end wall 24 of the bottom wall 54 of the insert 46.
  • the bottom wall 54 runs along the inside of the end wall 24, with a flat filter 56 between the inside of the end wall 24 and the outside of the intermediate wall 54 can be provided. This is in the Fig. 5 drawn.
  • the filter 56 may previously have been fixed on the outside of the bottom wall 54 of the insert 46 before the insert 46 is inserted into the outer body 18 and connected to it.
  • the bottom wall 54 and the end wall 24 run perpendicular to the longitudinal axis 27.
  • the bottom wall 54 has a circumferential web 58 protruding beyond its outside and lying on a circle, which can be inserted into a corresponding recess 60 in the end wall 24 in order to enable centering.
  • Other centering measures are also possible and are covered by the invention.
  • Corresponding centerings also include centering means arranged at points.
  • the insert 46 can likewise have a stepped geometry in the region of the inside of the step 124, which additionally ensures a desired coaxial alignment of the insert 46 with the outer body 18.
  • the bottom wall 54 merges into the peripheral wall 47 via a step 80, so that the insert 46 is basically composed of two cylindrical sections, namely the cross section delimited by the bottom wall 54 and the outer hollow cylindrical section of which the projections 48, 50, 52 protrude radially inward.
  • the insert 46 should be materially connected to the end wall 24, in particular by means of ultrasonic welding, whereby a liquid-tightness between the insert 46 and the end wall 24 is ensured.
  • a plastic spike 64 forming a hollow puncture spike with a tip 66 which, when the vial 10 is inserted into the insert 46, passes through its closure, thus establishing a connection via the female luer lock cone 26 can be made into a syringe body, not shown and connected to the Luer lock cone 26.
  • the hollow puncture spike can also be referred to as a hollow needle body or cannula body or some other description and is preferably made of plastic.
  • the “cannula” component is therefore not necessarily intended to indicate that metal is used as the material.
  • the support surface i.e. the outside of the bottom wall 54 of the insert 46, along which the filter 56 extends, is structured so that the liquid to be withdrawn is distributed and then via the female Luer lock cone 26 to the syringe body, not shown can arrive.
  • the housing that is to say the outer body 18, consists in particular of a polyolefin, in particular polypropylene.
  • the wall thickness of the outer peripheral wall 32 can be in the range between 1.2 mm and 1.6 mm.
  • Fig. 7 the adapter 14 is shown, which is connected to the vial 10 on the one hand and the syringe body 12 via the female Luer lock cone 26 on the other hand.
  • the female Luer lock cone 26 is known to interact with a male Luer lock cone of the syringe body 12.

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Fluid Mechanics (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)

Claims (15)

  1. Adaptateur (14) servant à transférer une substance d'un premier récipient (10) vers un second récipient (12), tel qu'un corps de seringue, comprenant une paroi périphérique (47) appropriée pour loger le premier récipient, le long de laquelle s'étend un corps de canule (64) entouré coaxialement au moins partiellement par ladite paroi, ainsi qu'une section cylindrique creuse (26) raccordée au corps de canule et raccordable au second récipient, sachant que le corps de canule s'étend par son axe longitudinal perpendiculairement à un côté d'une paroi (24) transversale par rapport à la paroi périphérique et la section cylindrique creuse s'étend par son axe longitudinal perpendiculairement à l'autre côté de la paroi,
    caractérisé en ce
    que l'adaptateur (14) présente un corps extérieur (18) en forme de pot avec une paroi périphérique extérieure (32) et la paroi (24) qui s'étend transversalement à l'axe longitudinal du corps extérieur, que le corps extérieur en forme de pot présente un élément rapporté (46) avec la paroi périphérique (47) logeant le récipient, et que le corps extérieur et l'élément rapporté forment une unité et ne peuvent pas être déplacés l'un par rapport à l'autre dans la direction longitudinale (27) de l'adaptateur (14).
  2. Adaptateur selon la revendication 1,
    caractérisé en ce
    que la paroi périphérique (47) de l'élément rapporté (46), entourée en particulier de manière concentrique par la paroi périphérique extérieure (32) du corps extérieur (18), par exemple un boîtier, présente des saillies (48, 50, 52) s'étendant radialement à l'intérieur de l'élément rapporté pour maintenir le premier récipient, sachant que la paroi périphérique s'étend à distance du côté intérieur (49) de la paroi périphérique extérieure au moins dans la zone des saillies.
  3. Adaptateur selon la revendication 1 ou 2,
    caractérisé en ce
    que l'élément rapporté (46) présente une paroi inférieure (54) qui, lorsque l'élément rapporté est relié au corps extérieur en forme de pot (18), éventuellement par l'intermédiaire d'un élément filtrant (56), repose sur la paroi (24).
  4. Adaptateur selon au moins la revendication 3,
    caractérisé en ce
    qu'un élément de centrage (58) opposé à la paroi périphérique (47) fait saillie de la paroi inférieure (54) de l'élément rapporté (46), s'engage dans un logement adapté (60) de la paroi (24) lorsque l'élément rapporté est relié au corps extérieur en forme de cylindrique creux (18) ou inversement, sachant que l'élément de centrage (58) est en particulier un élément nervuré de forme annulaire qui s'engage dans un logement (60) de forme annulaire, par exemple une rainure.
  5. Adaptateur selon au moins la revendication 3,
    caractérisé en ce
    que le corps de canule (64) sort de la paroi inférieure (54) de l'élément rapporté (46) et que la section cylindrique creuse (26) sort de la paroi (24) du corps extérieur en forme de pot (16, 18).
  6. Adaptateur selon au moins la revendication 3,
    caractérisé en ce
    que le côté extérieur de la paroi inférieure (54) de l'élément rapporté (46) est structuré, sachant que la paroi inférieure est éventuellement recouverte par un élément filtrant plat faisant office de filtre (56).
  7. Adaptateur selon au moins l'une des revendications précédentes,
    caractérisé en ce
    que l'élément rapporté (46) présente une première section cylindrique creuse s'étendant sur le côté inférieur et une seconde section de plus grand diamètre extérieur passant au-dessus d'une marche (80) et formant la paroi périphérique (147) et que, de préférence l'élément de centrage (58) s'étend à l'opposé de la marche.
  8. Adaptateur selon au moins l'une des revendications précédentes,
    caractérisé en ce
    que l'élément rapporté (46) est relié au corps extérieur en forme de pot (18) en étant étanche à l'air et aux liquides sur tout le pourtour et/ou que l'élément rapporté (46) est relié par adhérence de matière au corps extérieur en forme de pot (18) sur le côté inférieur, en particulier par soudage par ultrasons.
  9. Adaptateur selon au moins la revendication 3,
    caractérisé en ce
    que la paroi périphérique (47) de l'élément rapporté (46) est évidée au moins partiellement entre la paroi inférieure (54) et la saillie dirigée radialement vers l'intérieur (48, 50, 52).
  10. Adaptateur selon au moins la revendication 7,
    caractérisé en ce
    que la paroi périphérique (47) de l'élément rapporté (46) est évidée au moins partiellement entre la marche (80) et la saillie dirigée radialement vers l'intérieur (48, 50, 52).
  11. Adaptateur selon au moins l'une des revendications précédentes,
    caractérisé en ce
    que la paroi périphérique (47) de l'élément rapporté (46) s'étend au moins partiellement, de préférence entièrement, à distance de la surface intérieure de la paroi périphérique extérieure (32).
  12. Adaptateur selon au moins l'une des revendications précédentes,
    caractérisé en ce
    que le corps extérieur en forme de pot (18) et/ou l'élément rapporté (46) est ou sont une pièce moulée par injection, constituée en particulier d'une polyoléfine.
  13. Adaptateur selon au moins l'une des revendications précédentes,
    caractérisé en ce
    que le corps extérieur (18) présente un bord (25) en forme de bride qui fait saillie radialement sur la paroi périphérique extérieure (32), ledit bord étant de préférence aplati dans certaines zones, de préférence dans deux zones diamétralement opposées.
  14. Adaptateur selon au moins l'une des revendications précédentes,
    caractérisé en ce
    que la paroi (24) du corps extérieur (18) est une délimitation frontale de l'adaptateur (24), à partir de laquelle la section cylindrique creuse (26), de préférence sous la forme d'un cône Luer-Lock femelle, fait saillie au centre.
  15. Adaptateur selon au moins l'une des revendications précédentes,
    caractérisé en ce
    que le corps extérieur (18) est relié par adhérence de matière à l'élément rapporté (46) ou par une liaison mécanique, par exemple par enclenchement ou par vissage.
EP17721142.2A 2016-06-08 2017-05-03 Adaptateur Active EP3454818B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102016110569.4A DE102016110569B3 (de) 2016-06-08 2016-06-08 Adapter
PCT/EP2017/060503 WO2017211505A1 (fr) 2016-06-08 2017-05-03 Adaptateur

Publications (2)

Publication Number Publication Date
EP3454818A1 EP3454818A1 (fr) 2019-03-20
EP3454818B1 true EP3454818B1 (fr) 2020-11-18

Family

ID=58668898

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17721142.2A Active EP3454818B1 (fr) 2016-06-08 2017-05-03 Adaptateur

Country Status (14)

Country Link
US (1) US10888498B2 (fr)
EP (1) EP3454818B1 (fr)
JP (1) JP6957612B2 (fr)
KR (1) KR102360299B1 (fr)
CN (1) CN109562022B (fr)
AU (1) AU2017278373B2 (fr)
BR (1) BR112018075412B1 (fr)
CA (1) CA3026160C (fr)
DE (1) DE102016110569B3 (fr)
EA (1) EA036730B1 (fr)
ES (1) ES2853208T3 (fr)
IL (1) IL263438B (fr)
MX (1) MX2018015195A (fr)
WO (1) WO2017211505A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102021125666A1 (de) 2021-10-04 2023-04-06 Sfm Medical Devices Gmbh Transfervorrichtung

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202020101900U1 (de) * 2020-04-07 2021-07-13 Neoperl Gmbh Sanitäres Einsetzteil
US20230061566A1 (en) * 2021-08-25 2023-03-02 Scatter, LLC Systems, kits, and methods for contactless application of mixed concentrates and diluents

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011029184A1 (fr) * 2009-09-08 2011-03-17 Duoject Medical Systems Inc. Dispositif à liaison facile pour le transfert de fluide

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5060704A (en) 1990-05-25 1991-10-29 David Bull Laboratories Pty. Ltd. Suction transfer assembly
JPH05317383A (ja) * 1992-05-19 1993-12-03 Nissho Corp 薬剤容器との連通手段を備えた溶解液容器
FR2738550B1 (fr) * 1995-09-11 1997-11-07 Biodome Dispositif d'obturation d'un recipient lui-meme ferme, ensemble pour dispenser un produit comprenant un tel recipient et un tel dispositif d'obturation
US5924584A (en) 1997-02-28 1999-07-20 Abbott Laboratories Container closure with a frangible seal and a connector for a fluid transfer device
US6558365B2 (en) * 2001-01-03 2003-05-06 Medimop Medical Projects, Ltd. Fluid transfer device
JPWO2003000170A1 (ja) 2001-06-22 2004-10-07 株式会社大塚製薬工場 混注処理用口部材およびそれを用いた輸液容器
US6948522B2 (en) * 2003-06-06 2005-09-27 Baxter International Inc. Reconstitution device and method of use
JP3883527B2 (ja) * 2003-07-17 2007-02-21 ニプロ株式会社 トランスファーニードル
KR101092814B1 (ko) * 2006-05-25 2011-12-12 바이엘 헬스케어 엘엘씨 재구성 장치
JP5416848B2 (ja) * 2010-02-24 2014-02-12 メディモップ・メディカル・プロジェクツ・リミテッド 通気構造体を有する流体移送アセンブリ
JP5502579B2 (ja) 2010-04-21 2014-05-28 テルモ株式会社 医療用具接続具および薬剤投与具
US8857470B2 (en) * 2011-01-25 2014-10-14 Fresenius Kabi Deutschland Gmbh Connection device for connecting a first reservoir with a second reservoir
EP2680807B1 (fr) 2011-03-04 2016-08-10 Duoject Medical Systems Inc. Système de transfert à liaison facile
AP3940A (en) * 2012-02-02 2016-12-16 Becton Dickinson Holdings Pte Ltd Adaptor for coupling with a medical container
JP6174576B2 (ja) 2012-05-31 2017-08-02 学校法人近畿大学 曝露防止用キャップ
US9339438B2 (en) 2012-09-13 2016-05-17 Medimop Medical Projects Ltd. Telescopic female drug vial adapter
DE102012113002B4 (de) 2012-10-01 2014-04-30 Medac Gesellschaft für klinische Spezialpräparate mbH Transfervorrichtung zur Entnahme oder Übergabe eines Fluids
US10022301B2 (en) * 2013-03-15 2018-07-17 Becton Dickinson and Company Ltd. Connection system for medical device components
JP6199483B2 (ja) 2013-05-10 2017-09-20 メディモップ・メディカル・プロジェクツ・リミテッド インライン乾燥薬剤モジュールを有するバイアルアダプタを備える医療用デバイス
US9371925B2 (en) * 2013-07-30 2016-06-21 Tescom Corporation Fluid regulators having corrugated diaphragms
JP6511653B2 (ja) * 2013-08-07 2019-05-15 ユーエヌエル ホールディングス エルエルシーＵＮＬ Ｈｏｌｄｉｎｇｓ ＬＬＣ 格納式針組立体およびシリンジのためのリテーナ
US10556100B2 (en) * 2014-02-20 2020-02-11 Repro-Med Systems, Inc. Connector with filter
WO2015164339A1 (fr) * 2014-04-21 2015-10-29 Becton Dickinson and Company Limited Adaptateur pour seringue doté d'un mécanisme de régulation par désaccouplement
JP6340898B2 (ja) 2014-05-02 2018-06-13 株式会社ジェイ・エム・エス 医薬品容器用コネクタ
DE102015107312A1 (de) * 2014-12-30 2016-06-30 Sfm Medical Devices Gmbh Misch- und oder Transfervorrichtung

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011029184A1 (fr) * 2009-09-08 2011-03-17 Duoject Medical Systems Inc. Dispositif à liaison facile pour le transfert de fluide

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102021125666A1 (de) 2021-10-04 2023-04-06 Sfm Medical Devices Gmbh Transfervorrichtung
WO2023057424A1 (fr) 2021-10-04 2023-04-13 Sfm Medical Devices Gmbh Dispositif de transfert muni d'un couvercle d'ouverture

Also Published As

Publication number Publication date
JP2019517376A (ja) 2019-06-24
EA201892799A1 (ru) 2019-05-31
IL263438A (en) 2019-01-31
CA3026160C (fr) 2021-04-13
DE102016110569B3 (de) 2017-10-26
IL263438B (en) 2022-04-01
KR102360299B1 (ko) 2022-02-10
US10888498B2 (en) 2021-01-12
AU2017278373B2 (en) 2019-10-10
CA3026160A1 (fr) 2017-12-14
ES2853208T3 (es) 2021-09-15
EP3454818A1 (fr) 2019-03-20
MX2018015195A (es) 2019-04-22
CN109562022A (zh) 2019-04-02
BR112018075412B1 (pt) 2024-01-30
KR20190016076A (ko) 2019-02-15
AU2017278373A1 (en) 2019-01-03
JP6957612B2 (ja) 2021-11-02
BR112018075412A2 (pt) 2019-03-19
WO2017211505A1 (fr) 2017-12-14
EA036730B1 (ru) 2020-12-14
US20190142696A1 (en) 2019-05-16
CN109562022B (zh) 2022-02-11

Similar Documents

Publication Publication Date Title
EP3240520B1 (fr) Dispositif de mélange et/ou de transfert
EP2252249B1 (fr) Dispositif de mélange
EP3044104B1 (fr) Ampoule pour liquide médical et procédé de fabrication d'une ampoule
EP3454818B1 (fr) Adaptateur
WO2010034470A1 (fr) Connecteur doté d'une membrane pour le raccordement d'une seringue à un contenant ou à un tuyau flexible
WO2005074860A1 (fr) Appareil de transfert medical
DE102012113002A1 (de) Transfervorrichtung zur Entnahme oder Übergabe eines Fluids
EP2536377B1 (fr) Clapet de fermeture pour un récipient destiné à la réception de liquides médicaux et récipient
EP3054850A1 (fr) Module de prélèvement, en particulier d'échantillons sanguins
DE102006040670A1 (de) Vorrichtung zur Entnahme von Flüssigkeiten
WO2016015742A1 (fr) Récipient pourvu d'une pièce de tête qui est ou peut être rempli avec un fluide
EP3618962B1 (fr) Module de prélèvement ou tube à essai pour une faible quantité de liquide corporel, comprenant un élément de prolongement
DE19617024C2 (de) Sterile Verbindungsanordnung für einen eine medizinische Flüssigkeit enthaltenden Behälter
EP3519315A1 (fr) Capuchon de fermeture pour un contenant destiné à contenir un liquide médical
EP3375481B1 (fr) Élément de liaison
EP3544902B1 (fr) Bouteille munie d'un bec verseur et d'un godet doseur
EP2421492B1 (fr) Dispositif approprié pour le prélèvement de fluides médicaux contenus dans des emballages et emballage équipé de ce dernier
DE102009019503A1 (de) Für die Entnahme von medizinischen Flüssigkeiten aus Verpackungen geeignete Vorrichtung und damit ausgestattete Verpackung
EP1721595B2 (fr) Récipient pour délivrer des liquides médicaux
EP3290017B1 (fr) Bouteille pour plasma sanguin
EP3291913A1 (fr) Module de prélèvement notamment destiné au prélèvement de petites quantités
AT516438A1 (de) Handhabungsvorrichtung sowie Verfahren zu deren Herstellung

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: UNKNOWN

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20181212

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20191004

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

INTG Intention to grant announced

Effective date: 20200330

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAJ Information related to disapproval of communication of intention to grant by the applicant or resumption of examination proceedings by the epo deleted

Free format text: ORIGINAL CODE: EPIDOSDIGR1

GRAL Information related to payment of fee for publishing/printing deleted

Free format text: ORIGINAL CODE: EPIDOSDIGR3

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

INTC Intention to grant announced (deleted)
INTG Intention to grant announced

Effective date: 20200827

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

Free format text: LANGUAGE OF EP DOCUMENT: GERMAN

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 502017008263

Country of ref document: DE

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 1334951

Country of ref document: AT

Kind code of ref document: T

Effective date: 20201215

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: LUCHS AND PARTNER AG PATENTANWAELTE, CH

REG Reference to a national code

Ref country code: NL

Ref legal event code: MP

Effective date: 20201118

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210218

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210318

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210219

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210218

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210318

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG9D

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 502017008263

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2853208

Country of ref document: ES

Kind code of ref document: T3

Effective date: 20210915

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20210819

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20210503

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

REG Reference to a national code

Ref country code: BE

Ref legal event code: MM

Effective date: 20210531

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20210503

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20210318

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20210531

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118

REG Reference to a national code

Ref country code: AT

Ref legal event code: MM01

Ref document number: 1334951

Country of ref document: AT

Kind code of ref document: T

Effective date: 20220503

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20170503

Ref country code: AT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220503

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20230526

Year of fee payment: 7

Ref country code: FR

Payment date: 20230526

Year of fee payment: 7

Ref country code: DE

Payment date: 20230524

Year of fee payment: 7

Ref country code: CH

Payment date: 20230605

Year of fee payment: 7

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20230524

Year of fee payment: 7

Ref country code: ES

Payment date: 20230727

Year of fee payment: 7

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20201118