EP3284480A4 - Composition pharmaceutique pour la prévention et/ou le traitement de la dermatite atopique contenant comme principe actif un antagoniste de l'il-31 - Google Patents
Composition pharmaceutique pour la prévention et/ou le traitement de la dermatite atopique contenant comme principe actif un antagoniste de l'il-31 Download PDFInfo
- Publication number
- EP3284480A4 EP3284480A4 EP16780054.9A EP16780054A EP3284480A4 EP 3284480 A4 EP3284480 A4 EP 3284480A4 EP 16780054 A EP16780054 A EP 16780054A EP 3284480 A4 EP3284480 A4 EP 3284480A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- antagonist
- prevention
- treatment
- pharmaceutical composition
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2015082699 | 2015-04-14 | ||
JP2016041641 | 2016-03-04 | ||
PCT/JP2016/061859 WO2016167263A1 (fr) | 2015-04-14 | 2016-04-13 | Composition pharmaceutique pour la prévention et/ou le traitement de la dermatite atopique contenant comme principe actif un antagoniste de l'il-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3284480A1 EP3284480A1 (fr) | 2018-02-21 |
EP3284480A4 true EP3284480A4 (fr) | 2018-12-05 |
Family
ID=57126544
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP16780054.9A Pending EP3284480A4 (fr) | 2015-04-14 | 2016-04-13 | Composition pharmaceutique pour la prévention et/ou le traitement de la dermatite atopique contenant comme principe actif un antagoniste de l'il-31 |
Country Status (12)
Country | Link |
---|---|
US (2) | US10544227B2 (fr) |
EP (1) | EP3284480A4 (fr) |
JP (5) | JP6654967B2 (fr) |
KR (1) | KR20170134748A (fr) |
CN (1) | CN107614016B (fr) |
BR (1) | BR112017022101A2 (fr) |
CA (1) | CA2980992C (fr) |
MA (1) | MA43918A (fr) |
MX (2) | MX2017013141A (fr) |
RU (1) | RU2749512C2 (fr) |
TW (3) | TW202327654A (fr) |
WO (1) | WO2016167263A1 (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20170134748A (ko) | 2015-04-14 | 2017-12-06 | 추가이 세이야쿠 가부시키가이샤 | Il-31 안타고니스트를 유효 성분으로서 함유하는 아토피성 피부염의 예방용 및/또는 치료용 의약 조성물 |
WO2017126488A1 (fr) * | 2016-01-18 | 2017-07-27 | 持田製薬株式会社 | Composition de traitement du psoriasis et procédé de traitement |
WO2018156180A1 (fr) | 2017-02-24 | 2018-08-30 | Kindred Biosciences, Inc. | Anticorps anti-il31 à usage vétérinaire |
BR112020016144A2 (pt) * | 2018-02-09 | 2020-12-15 | Nestlé Skin Health Sa | Nemolizumabe no tratamento de dermatite atópica com escoriação moderada a grave |
EP3797752A4 (fr) | 2018-05-21 | 2022-03-02 | Chugai Seiyaku Kabushiki Kaisha | Formulation lyophilisée scellée dans un flacon en verre |
JP2022545259A (ja) * | 2019-08-29 | 2022-10-26 | キンドレッド バイオサイエンシズ インコーポレイテッド | 動物用の抗il31抗体 |
CN110563844A (zh) * | 2019-09-04 | 2019-12-13 | 华中农业大学 | 一种抗犬白介素31受体的多克隆抗体及其应用 |
CN114728064A (zh) | 2019-11-20 | 2022-07-08 | 中外制药株式会社 | 含抗体制剂 |
US20230047844A1 (en) * | 2020-01-24 | 2023-02-16 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compounds and methods for treating or reducing pruritus |
JPWO2022113316A1 (fr) * | 2020-11-30 | 2022-06-02 | ||
CN115181183B (zh) * | 2022-06-23 | 2023-11-03 | 恺佧生物科技(上海)有限公司 | 一种il-31ra抗体以及其构建方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2734549A1 (fr) * | 2011-07-21 | 2014-05-28 | Zoetis LLC | Anticorps monoclonal dirigé contre l'interleukine-31 |
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KR20170134748A (ko) | 2015-04-14 | 2017-12-06 | 추가이 세이야쿠 가부시키가이샤 | Il-31 안타고니스트를 유효 성분으로서 함유하는 아토피성 피부염의 예방용 및/또는 치료용 의약 조성물 |
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BR112019021364A2 (pt) | 2017-04-11 | 2020-05-05 | Kiniksa Phamaceuticals Ltd | formulação estável de anticorpo anti-osmr |
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- 2016-04-13 US US15/563,743 patent/US10544227B2/en active Active
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ANONYMOUS: "Randomized, double-blind, placebo-controlled, multi-center, multi-dose Phase II study of anti-interleukin-31 receptor A monoclonal antibody CIM331 (nemolizumab) in patients with moderate-to-severe atopic dermatitis", 4 March 2016 (2016-03-04), XP055517070, Retrieved from the Internet <URL:https://integrity.thomson-pharma.com/integrity/xmlxsl/pk_ref_list.xml_show_ficha_ref?p_ref_id=2473202> [retrieved on 20181018] * |
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WO2016167263A1 (fr) | 2016-10-20 |
RU2017138551A3 (fr) | 2019-09-30 |
JP2023134842A (ja) | 2023-09-27 |
MX2021013139A (es) | 2021-11-25 |
JP6887212B2 (ja) | 2021-06-16 |
US20200102396A1 (en) | 2020-04-02 |
JP6654967B2 (ja) | 2020-02-26 |
KR20170134748A (ko) | 2017-12-06 |
US20180079817A1 (en) | 2018-03-22 |
EP3284480A1 (fr) | 2018-02-21 |
US11773173B2 (en) | 2023-10-03 |
JP2020075937A (ja) | 2020-05-21 |
MA43918A (fr) | 2018-12-05 |
TWI738648B (zh) | 2021-09-11 |
BR112017022101A2 (pt) | 2018-07-31 |
MX2017013141A (es) | 2018-02-21 |
TW201642905A (zh) | 2016-12-16 |
TW202146048A (zh) | 2021-12-16 |
JP2021105051A (ja) | 2021-07-26 |
TWI826814B (zh) | 2023-12-21 |
US10544227B2 (en) | 2020-01-28 |
JP2017160178A (ja) | 2017-09-14 |
RU2017138551A (ru) | 2019-05-14 |
TW202327654A (zh) | 2023-07-16 |
CN107614016B (zh) | 2022-06-17 |
CN107614016A (zh) | 2018-01-19 |
CA2980992A1 (fr) | 2016-10-20 |
JP2021193124A (ja) | 2021-12-23 |
RU2749512C2 (ru) | 2021-06-11 |
CA2980992C (fr) | 2024-01-23 |
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