EP3041437A1 - Intralaryngeale prothese - Google Patents
Intralaryngeale protheseInfo
- Publication number
- EP3041437A1 EP3041437A1 EP14761346.7A EP14761346A EP3041437A1 EP 3041437 A1 EP3041437 A1 EP 3041437A1 EP 14761346 A EP14761346 A EP 14761346A EP 3041437 A1 EP3041437 A1 EP 3041437A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- valve
- tubular body
- intra
- prosthesis
- laryngeal prosthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/20—Epiglottis; Larynxes; Tracheae combined with larynxes or for use therewith
- A61F2/203—Epiglottis; Larynxes; Tracheae combined with larynxes or for use therewith comprising an air passage from trachea to oesophagus or to pharynx; Artificial epiglottis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/20—Epiglottis; Larynxes; Tracheae combined with larynxes or for use therewith
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0071—Three-dimensional shapes spherical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0018—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in elasticity, stiffness or compressibility
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0071—Additional features; Implant or prostheses properties not otherwise provided for breakable or frangible
Definitions
- the present invention relates to an intra-laryngeal prosthesis. STATE OF THE PRIOR ART
- the main function of the larynx is to seal, during swallowing, the airways to protect them and prevent the bolus from entering, instead of passing through the esophagus.
- This obturation is done by neuromuscular reflex of closure of the glottis, resulting from the adduction of muscle groups arranged on three levels (glottic ary-epi, ventricular bands and vocal cords). In case of dysfunction at one of these levels, it ensues disorders of swallowing, the larynx can no longer ensure proper closure of the airways, so that the bolus can pass into them.
- the document EP 0 815 807 describes an intra-laryngeal prosthesis, which makes it possible to remedy the dysfunction of the larynx.
- the intra-laryngeal prosthesis comprises a tubular body which is intended to be inserted into the larynx of a patient.
- the tubular body having one of its ends shaped bevel.
- On this end is fixed a shutter valve which is aligned with the beveled end of the tubular body.
- the shutter valve prevents elements from entering the tubular body.
- the beveled end is pierced by orifices, which have a substantially crenellated shape and connect the inside and outside of said tubular body.
- these orifices tend to be blocked by saliva or food bolus, which hampers the patient's breathing.
- the invention aims to remedy the drawbacks of the state of the art by proposing an intra-laryngeal prosthesis which prevents the passage of the bolus and saliva into the airways, which does not become clogged and which allows the patient to breathe. easily.
- a first aspect of the invention relates to an intralaryngeal prosthesis configured to be introduced into a larynx, the prosthesis comprising:
- a tubular body having a proximal end surrounding a proximal opening;
- a valve the valve having a proximal end and a distal end;
- a hinge connecting the proximal end of the valve to the proximal end of the tubular body so that the valve can be placed in a normal (or at rest) position in which it covers the proximal opening or in an open position in the which it does not cover the proximal opening;
- valve being arranged so that, in the normal position:
- the distal end of the valve forms a rim that covers a portion of the tubular body and that
- the valve forms a rim which covers a portion of the tubular body prevents the saliva and the food bolus evacuated from the surface of the valve being discharged into the tubular body.
- the valve is configured so that a space exists between the valve, and more precisely between its flange, and the tubular body. The air can therefore enter the tubular body through this space, without saliva or food bolus entering the tubular body due to the rim.
- the intra-laryngeal prosthesis may also have one or more of the following features taken independently or in any technically possible combination.
- the valve has a domed domed shape, which prevents the stagnation of the bolus and saliva on the valve, since these elements are evacuated by gravity.
- valve is flat (it could then be beveled with respect to the tubular body, that is to say that the valve plant is not perpendicular to the valve. axis of the tubular body).
- the other geometries of the valves must be determined in such a way that they prevent stagnation of the bolus or saliva on the valve, and must slide into the esophagus because of gravity.
- the tubular body preferably extends, at least over a portion, along a reference axis so as to be inserted into the larynx of a patient.
- the tubular body has two zones:
- a first zone (I) (for example cylindrical) extending along a reference axis (this zone being intended to be inserted wholly or partly in the larynx of a patient, or at the end a tracheal ring as described in the application WO 2013/079362)
- a second zone (II) (including the proximal end) having outer dimensions smaller than the outer dimensions of the first zone (such that the first zone is moved to the second zone by narrowing the outer dimensions of the body tubular).
- the inner lumen (cross section, proximal opening (8)) of the second zone is smaller than the inner lumen defined in the first zone.
- This second zone may be of frustoconical shape, or in the form of a bevel (or in the form of a whistle or a recorder's mouthpiece).
- the second zone (II) does not necessarily have an axis of symmetry.
- the principle of the implementation of this embodiment allows to use a valve having the same diameter as the first cylindrical zone of the tubular body, while maintaining the space between the proximal portion of the tubular body and said valve.
- the dimensions of the valve are greater than those of the proximal end of said tubular body.
- the use of a larger valve (diameter) than that of the tubular body may cause discomfort after implantation in the patient.
- valve forms a rim which covers a portion of the tubular body and that a space exists between this part of the tubular body and the rim can be achieved in different ways.
- the distal end of the flap forms a rim that covers a portion of the tubular body and that
- a space exists between the distal end of the valve and the tubular body so that air can enter the proximal opening of the tubular body through this space.
- the valve is preferably offset in a direction opposite to that of the hinge. It can also be provided that the valve has transverse dimensions greater than those of the tubular body so that:
- the distal end of the valve forms a rim that covers a portion of the tubular body and that
- a space exists between the distal end of the valve and the tubular body so that air can enter the proximal opening of the tubular body through this space.
- the valve comprises a lid having weakened zones, the lid being able to be pierced by an intubation probe.
- the lid preferably comprises a reception area adapted so that an intubation probe can be placed in this reception area without the risk of slipping on the upper face of the valve.
- the valve has a lower face, the hinge being elastically deformable so as to allow the passage of the valve in the open position when a force greater than a threshold force is exerted on the underside of the valve.
- the hinge allows the opening of the flap to the top.
- the valve has a lower face, the hinge being elastically deformable so as to return the valve in the normal position when no force greater than a threshold force is exerted on the underside of the valve.
- the valve in normal breathing, the valve remains in the normal position and therefore it covers the proximal opening of the tubular body so as to protect it.
- the valve has an upper face, the upper face of the valve being treated, at least in part, a release treatment.
- the non-stick treatment strengthens the effect of the shape of the valve in order to avoid stagnation of the bolus and saliva on the valve.
- This non-stick treatment may for example be achieved by polishing or microbotting the upper face of the valve or by a release layer deposited on the valve.
- the proximal end of the tubular body may also be treated by a surface treatment.
- the valve comprises centering means arranged on its lower face, the proximal end of the tubular body having complementary centering means, the centering means of the valve being arranged to cooperate with the complementary means of the tubular body so as to guide the valve and ensure that it returns to the desired position as it moves from the open position to the normal position.
- the centering means may be formed by a truncated centering cone projecting from the underside of the valve.
- the complementary centering means can in this case be formed by a truncated conical orifice formed in a transverse wall of the tubular body, the orifice being adapted to receive the centering cone.
- the tubular body comprises a resiliently deformable central portion, which allows to easily insert without surgery the intra-laryngeal prosthesis in the larynx of a patient.
- the central portion of the tubular body is preferably made of silicone.
- the proximal end of the tubular body is preferably made of titanium so as to facilitate the attachment of the hinge to the tubular body and to avoid deformation of the proximal end when the hinge is deformed.
- the valve is made of titanium so as to be rigid enough not to deform under the effect of the bolus or saliva.
- the valve is elliptical so as to better adapt to the patient's anatomy.
- the hinge is made of silicone, but it can also be with any other biocompatible elastic material.
- the hinge has a sufficient restoring force to allow the valve to cover the proximal opening when it is at rest, but to open when a force greater than a threshold force is applied to the face bottom of the flap.
- the tubular body may be flexible, semi-rigid or even rigid.
- said tubular body has projecting external nipples, for fixing said prosthesis in position inside the larynx, by pressing said nipples against the inner wall thereof.
- the distal end of said tubular body, opposite the proximal end has a smaller diameter than the side of the proximal end, or that the central portion of the tubular body.
- the distal end is beveled.
- FIG. 2 a perspective view of the intra-laryngeal prosthesis of FIG. 1;
- FIG. 6 an enlarged view of the inside of the prosthesis of FIG.
- FIG. 7 a sectional view of the zone (I) containing the proximal opening (8) of the tubular body (2) in the form of a recorder mouthpiece, and a small portion of the zone (I). ) of the tubular body (2), and the valve (10) whose diameter is identical to that of the cylindrical zone (I) of the tubular body (2).
- This figure shows the valve (10) in the rest position.
- the gap (17) between the distal end (15) of the valve (10) and the tubular body is also observed, allowing air to flow and the patient to breathe.
- the intra-laryngeal prosthesis 1 comprises a tubular body 2.
- the tubular body 2 extends along a reference axis 3.
- the tubular body 2 has a tubular shape around the reference axis.
- the tubular body 2 preferably comprises a central portion 4.
- the central portion 4 is preferably elastically deformable.
- the central portion 4 is preferably made of silicone.
- the intra-laryngeal prosthesis can thus be inserted easily by the endobuccal route and without surgery in the larynx of a patient.
- the central portion 4 may be provided with asperities 5 so as to facilitate its retention in the larynx of the patient.
- the prosthesis can be put in place without tracheotomy.
- the central portion is present in the zone (I).
- the tubular body 2 also has a proximal end 6 and a distal end 7.
- the proximal end 6 and distal 7 are opposite.
- the distal end 7 is preferably bevelled.
- the proximal end 6 is preferably rigid, so as to be more resistant, and to allow the fixing of a hinge and to allow the good return in position of the valve on the tubular body.
- the rigid proximal end 6 also makes it possible to fix the ancillary for placing the intra-laryngeal prosthesis.
- the proximal end 6 is preferably made of titanium.
- the proximal end 6 is pierced by a proximal opening 8.
- the proximal opening 8 opens onto a cylindrical opening 9 which passes right through the tubular body 2.
- the intra-laryngeal prosthesis 1 preferably comprises a valve 10.
- the valve 10 can be placed in a normal position in which it covers the proximal opening 8 and an open position in which it does not cover the proximal opening 8.
- the valve 10 is preferably made of titanium.
- the valve 10 has a lower face 12 and an upper face 13.
- the lower face 12 of the valve is directed towards the tubular body.
- the upper face 13 of the valve is directed away from the tubular body.
- the valve 10 has a proximal end 14 and a distal end 15.
- the lower face 12 of the valve is preferably provided with centering means 18 arranged to fit in complementary centering means 19 of the tubular body 2 so as to provide the good positioning of the flap as it moves from the open position to the normal position.
- These centering means 18 may for example comprise a centering cone, the complementary centering means 19 having a complementary conical orifice.
- the valve 10 is connected to the tubular body 2 by a hinge January 1 which is elastically deformable so as to allow the passage of the valve from the normal position to the open position and vice versa.
- the hinge is flexible, it can bend.
- the proximal end 14 of the valve is connected to the hinge January 1.
- the hinge January 1 is preferably made of silicone.
- the hinge January 1 is shaped to allow the passage of the valve in the open position when a force greater than a threshold force is applied to the lower face 12 of the valve 10.
- the valve opens to facilitate the expiration of the patient. This is also the case in case of coughing or sneezing.
- the surgeon can also open the flap to make a check airways, for example by endoscope.
- the hinge January 1 is shaped to bring the valve 10 in the normal position when no force greater than the threshold force is applied to the lower face 12 of the valve.
- the valve 10 is always returned to the normal position so as to protect the proximal opening 8, except in case of force greater than the threshold force. In normal breathing, the valve 10 is in the normal position.
- the intra-laryngeal prosthesis has the characteristics detailed below. after.
- the valve 10 preferably has a convex shape. More specifically, the valve 10 preferably has a convex shape and a concavity facing the tubular body 2. Thus, by gravity effect, the food bolus that would be deposited on the valve would be evacuated. The dome shape thus makes it possible to avoid stagnation of the bolus and saliva on the valve. In addition, to enhance this effect, one can provide a release coating on the upper surface 13 of the valve.
- the valve has a symmetry of revolution.
- it could also have a valve which has an elliptical cross section, of greater axis parallel to a transverse axis 20 connecting the proximal end of the valve at its distal end, or a larger axis perpendicular to such a transverse axis 20.
- valve 10 is arranged so that:
- the distal end 15 of the valve forms a flange 16 which covers a portion 30 of the tubular body 2 and that
- a space 17 exists between the distal end 15 of the valve 10 and the tubular body 2 so that air can enter the proximal opening 8 of the tubular body 2 by this space 17.
- the valve has transverse dimensions greater than the transverse dimensions of the body
- transverse dimensions refers to a dimension taken perpendicularly to the reference axis 3 of the tubular body.
- valve 10 it is possible to offset the valve 10 relative to the tubular body, so that the valve 10 is offset in the opposite direction to the hinge 1 1.
- these two embodiments can be used independently of one another or in combination.
- the space 17 and the space between the lower face 12 of the valve and the transverse wall at the distal end 6 form a baffle which allows the air to enter the proximal opening 8, while avoiding that food or saliva can enter the proximal opening 8.
- the flange 16 is preferably cut to fit the tubular body 2 in the longitudinal direction, on either side of the space 17.
- the valve 10 may be provided with a lid 31 which has weakened zones 32 so that the lid can be pierced by an intubation probe in case of emergency intubation.
- the lid 31 is preferably made of silicone.
- the lid 31 is preferably overmolded on the valve 10 at the same time as the hinge January 1 which is also preferably overmolded on the valve 10.
- the valve 10, preferably made of titanium, is provided with through holes placed on the periphery of the seal which make it possible to ensure the mechanical strength of the seal 31 on the valve 10.
- the seal 31 is hermetic as long as it is not torn and is sufficiently strong not to be pierced by food or saliva.
- the cover 31 may for example be made in the following manner: firstly, the seal 31 of silicone is overmolded on the valve 10.
- a tool provided with blades allows to come notch the center of the opercule 31, preferably in the form of cross, cross, or flake-shaped. These notches are not through: a thin silicone thickness allows to join together parts of the cap. This keeps a seal between the top and bottom of the valve. This technical solution will, once pierced by an intubation probe, to keep the petals of the seal linked to the valve.
- the lid may be flat, as shown in Figures 1 and 4, or curved.
- the lid may comprise a reception zone 33 adapted to receive the end of a probe so as to prevent the end of the probe from slipping on the lid.
- the reception area preferably forms a concave hollow of concavity turned to the opposite of the tubular body 2.
- the concavity of the reception zone 33 is preferably opposite to the concavity of the valve 10.
- the reception zone 33 is preferably aligned with the reference axis 3 of the body tubular 2, so as to initiate the guidance of an intubation probe in the axis of the tubular body. Consequently, when the valve is off-axis with respect to the tubular body, the receiving zone is off-axis with respect to the valve.
- valve could in particular have a shape other than the curved shape: it could for example be triangular or trapezoidal.
Landscapes
- Health & Medical Sciences (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1358530A FR3009951B1 (fr) | 2013-09-05 | 2013-09-05 | Prothese intra-laryngee |
PCT/EP2014/068913 WO2015032886A1 (fr) | 2013-09-05 | 2014-09-05 | Prothèse intra-laryngée |
Publications (1)
Publication Number | Publication Date |
---|---|
EP3041437A1 true EP3041437A1 (de) | 2016-07-13 |
Family
ID=49326776
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP14761346.7A Withdrawn EP3041437A1 (de) | 2013-09-05 | 2014-09-05 | Intralaryngeale prothese |
Country Status (6)
Country | Link |
---|---|
US (1) | US9913713B2 (de) |
EP (1) | EP3041437A1 (de) |
CN (1) | CN105555228A (de) |
CA (1) | CA2923113A1 (de) |
FR (1) | FR3009951B1 (de) |
WO (1) | WO2015032886A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6595232B2 (ja) | 2015-07-02 | 2019-10-23 | ソニー・オリンパスメディカルソリューションズ株式会社 | 内視鏡用撮像装置、内視鏡装置、及び内視鏡用ケーブル |
FR3048606B1 (fr) * | 2016-03-10 | 2018-03-16 | Protip Medical | Prothese intra-laryngee comprenant une jupe d’etancheite |
DE102017103623B3 (de) * | 2017-02-22 | 2018-05-17 | Andreas Fahl Medizintechnik-Vertrieb Gmbh | Einführhilfe für Stimmprothesen |
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US20090026660A1 (en) * | 2001-04-11 | 2009-01-29 | Helix Medical, Llc | Methods of making antimicrobial voice prothesis devices |
US7240676B2 (en) | 2002-12-16 | 2007-07-10 | Children's Hospital Medical Center | Tracheotomy valve unit |
DE202004010341U1 (de) | 2003-12-08 | 2004-11-18 | Nazaradeh, Fridun, Dr.med. Dipl.-Ing. | Vorrichtung zur digitalen Konservierung und Verwaltung individueller stimmhafter Anteile der menschlichen Stimme |
SE528922C2 (sv) | 2004-04-08 | 2007-03-13 | Atos Medical Ab | Förfarande och anordning för säkert insättning och montering av en rörformad anordning i en flexibel vägg samt tillverkningsförfarande för nämnda insättningsanordning |
WO2005102458A2 (en) | 2004-04-19 | 2005-11-03 | The Board Of Trustees, The Leland Stanford Junior University | Airway implant devices and methods of use |
SE528253C2 (sv) | 2005-01-07 | 2006-10-03 | Atos Medical Ab | Röstprotes, insättningsverktyg och förfarande |
US8800564B2 (en) | 2005-03-09 | 2014-08-12 | Elaine D. Scott | Tracheostomy appliances and methods for the treatment of sleep apnea syndromes |
US7998200B2 (en) | 2005-06-06 | 2011-08-16 | Helix Medical, Llc | Voice prosthesis device |
FR2891133B1 (fr) | 2005-09-23 | 2009-06-12 | Protip Sas Soc Par Actions Sim | Implant phonatoire |
FR2892621B1 (fr) | 2005-10-27 | 2009-08-21 | Protip Sas Soc Par Actions Sim | Procede d'obtention d'un implant composite biocompatible |
US20070133859A1 (en) | 2005-10-28 | 2007-06-14 | Imaging Business Machines, Llc | Methods and systems for reading magnetic ink character recognition information |
EP2043611A2 (de) | 2006-06-30 | 2009-04-08 | Nucryst Pharmaceuticals Corp. | Metallhaltige formulierungen und anwendungsverfahren |
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DE202007000655U1 (de) | 2007-01-16 | 2007-03-22 | Neubauer, Norbert | Einführungsvorrichtung zum Anbringen einer rohrförmigen Hülse in eine flexible Wand |
FR2924331B1 (fr) | 2007-12-03 | 2010-01-15 | Protip Sas | Dispositif a clapets destine a etre implante au sein d'un larynx dysfonctionnel ou d'une prothese de larynx |
CN101917933A (zh) | 2007-12-06 | 2010-12-15 | 瓦利卡帕德利尔·马修·克瑞安 | 可植入的机械心瓣膜组件 |
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GB0903250D0 (en) | 2009-02-26 | 2009-04-08 | Depuy Int Ltd | Support structure implant for a bone cavity |
JP2010207276A (ja) | 2009-03-06 | 2010-09-24 | Gc Corp | 歯科インプラントのアバットメント用ワックス模型台 |
GB0918995D0 (en) | 2009-10-29 | 2009-12-16 | Univ Hull | A speech valve, a tool for facilitating insertion of a speech valve and a tool for holding a speech valve |
FR2979534B1 (fr) | 2011-09-06 | 2013-12-27 | Protip | Nouvelle prothese intralaryngee |
US9339339B2 (en) | 2011-09-16 | 2016-05-17 | Boston Scientific Scimed, Inc. | Medical device and method for conducting a surgery through a body opening |
FR2983060B1 (fr) | 2011-11-30 | 2013-12-06 | Protip | Dispositif medical de support pour implant ou prothese |
US10321987B2 (en) | 2014-04-23 | 2019-06-18 | Medtronic, Inc. | Paravalvular leak resistant prosthetic heart valve system |
-
2013
- 2013-09-05 FR FR1358530A patent/FR3009951B1/fr active Active
-
2014
- 2014-09-05 CN CN201480048953.3A patent/CN105555228A/zh active Pending
- 2014-09-05 US US14/916,811 patent/US9913713B2/en not_active Expired - Fee Related
- 2014-09-05 WO PCT/EP2014/068913 patent/WO2015032886A1/fr active Application Filing
- 2014-09-05 EP EP14761346.7A patent/EP3041437A1/de not_active Withdrawn
- 2014-09-05 CA CA2923113A patent/CA2923113A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2923113A1 (fr) | 2015-03-12 |
US20160228239A1 (en) | 2016-08-11 |
CN105555228A (zh) | 2016-05-04 |
FR3009951A1 (fr) | 2015-03-06 |
WO2015032886A1 (fr) | 2015-03-12 |
FR3009951B1 (fr) | 2017-01-20 |
US9913713B2 (en) | 2018-03-13 |
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