EP2840026B1 - Agencement pour l'emballage de portions de médicaments dans des emballages de distribution et procédé de re-remplissage d'un récipient de stockage d'une station de stockage et de dosage d'un distributeur automatique en portions de médicaments - Google Patents

Agencement pour l'emballage de portions de médicaments dans des emballages de distribution et procédé de re-remplissage d'un récipient de stockage d'une station de stockage et de dosage d'un distributeur automatique en portions de médicaments Download PDF

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Publication number
EP2840026B1
EP2840026B1 EP13181201.8A EP13181201A EP2840026B1 EP 2840026 B1 EP2840026 B1 EP 2840026B1 EP 13181201 A EP13181201 A EP 13181201A EP 2840026 B1 EP2840026 B1 EP 2840026B1
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EP
European Patent Office
Prior art keywords
storage
identifier
station
refilling
read
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP13181201.8A
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German (de)
English (en)
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EP2840026A1 (fr
Inventor
Christoph Hellenbrand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson Rowa Germany GmbH
Original Assignee
CareFusion Germany 326 GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DK13181201.8T priority Critical patent/DK2840026T3/en
Application filed by CareFusion Germany 326 GmbH filed Critical CareFusion Germany 326 GmbH
Priority to EP13181201.8A priority patent/EP2840026B1/fr
Priority to ES13181201.8T priority patent/ES2581517T3/es
Priority to PT131812018T priority patent/PT2840026T/pt
Priority to US14/912,817 priority patent/US10307338B2/en
Priority to PCT/EP2014/066815 priority patent/WO2015024771A1/fr
Priority to CN201480046590.XA priority patent/CN105492325B/zh
Publication of EP2840026A1 publication Critical patent/EP2840026A1/fr
Application granted granted Critical
Publication of EP2840026B1 publication Critical patent/EP2840026B1/fr
Priority to US16/393,782 priority patent/US11039984B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0076—Medicament distribution means
    • A61J7/0084—Medicament distribution means for multiple medicaments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00—Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B5/10—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles
    • B65B5/101—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity
    • B65B5/103—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity for packaging pills or tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B1/04—Methods of, or means for, filling the material into the containers or receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B1/30—Devices or methods for controlling or determining the quantity or quality or the material fed or filled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2205/00—General identification or selection means
    • A61J2205/10—Bar codes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2205/00—General identification or selection means
    • A61J2205/60—General identification or selection means using magnetic or electronic identifications, e.g. chips, RFID, electronic tags

Definitions

  • the invention relates to an arrangement comprising a dispensing machine for packaging medicament portions in dispensing packs, the dispenser having a plurality of storage and dispensing stations, each of which can receive a plurality of medicament portions and dispense them one by one, a packaging device which satisfies the requirements of the storage reservoirs. and dosing stations receives dispensed drug portions and dispenses them into dispensing packages, and has a control device controlling the supply storage and dispensing stations and the packaging device, each storage storage and dispensing station having a stationary part attached to a frame of the dispensing machine a detachable part containing an information storage, and wherein the stationary part is associated with a reading device for reading the information storage.
  • the information storage is part of an RF tag and stores information about the tablets contained in the reservoir, such as their name, the number of tablets contained and the weight of the tablet.
  • the stationary part includes a tablet information access unit connected to a host computer and assigned an address.
  • the tablet information access unit includes an RF module having an antenna for communicating with the RF tag.
  • the information to be stored in the memory of the RF tag will be at a first touchdown of the removable part on the stationary Part under the control of the host computer via the RF module of the tablet information access unit inscribed, wherein the address of the tablet information access unit serves as identification information.
  • the host computer may request the tablet information access unit address information and the tablet information retrieved from the tablet tag access unit memory from the memory of the RF tag, and store it in its memory along with the position of the storage-and-dispensing station.
  • a similar arrangement is from the US 5,930,145 A known.
  • This document describes an arrangement for packaging medicament portions in delivery packs, consisting of a dispensing machine (tablet dispensing unit 1 and tablet discharge control unit 2) and a refilling station (work table 4 with tablet replenishment unit 5).
  • the dispensing machine has a plurality of storage and dispensing stations (tablet feeders 11), each of which can receive a plurality of drug portions and dispensed individually.
  • the dispenser also includes a packaging device that receives and dispenses the drug portions dispensed from the storage and dispensing stations into dispensing packages, and a controller controlling the storage and dispensing stations and the packaging device.
  • Each storage-and-dosing station comprises a stationary part (motor base 14) attached to a frame of the dispensing machine and a removable part (cartridge 15) containing a refillable portion for drug portions, the detachable part (15) comprising an information memory (RAM 29 ), which among other things stores the number of drug portions currently contained in the reservoir.
  • the dispensing machine further comprises a reading device for reading the information memory.
  • control unit it is an object of the invention to enable the control unit to more reliably detect whether the reservoir of a (re) attached to a stationary part removable part was refilled or only temporarily removed for other reasons and whether the Data of the refill have been correctly transferred to a database of the control unit.
  • the arrangement according to the invention for packaging medicament portions in delivery packs consists of a dispensing machine and at least one refill station.
  • the dispensing machine has a plurality of storage and dosing stations, each of which can receive and dispense a plurality of drug portions, a packaging device that receives the dispensed from the storage and dispensing stations drug portions and brings in dispensing packs, and a the supply storage and dosing stations and the packaging device controlling control device.
  • Each storage and dosing station includes one on a frame or housing of the Dispensers attached stationary part and a refillable reservoir for drug portions containing removable part.
  • the detachable part has an information storage which stores, inter alia, an identifier of the detachable part.
  • the stationary part is associated with a reading device for reading the information memory.
  • the at least one refill station serves to refill the reservoir of a removed detachable part of the drug storage supply-and-dispensing station.
  • Each store contains a space for a fill handle.
  • the refill identifier is changed at the refill station each time the reservoir has been refilled so that refilling upon reading of the information store by the reader after re-placement of the detachable member on the stationary part thereof or another storage repository.
  • the refill station is coupled to a database and reads the identifier of the newly filled detachable part and stores it together with the changed filling ID in the database
  • the control device of the dispensing machine is configured that they receive from the read devices of the storage-and-dosing stations the read identifiers with the associated filling identifiers of the attached detachable parts, read from the database the filling identifier stored together with an identifier, and read the read identifier and the ge compare the read fill ID of an attached detachable part with the corresponding values from the database and generate an error signal if it does not match.
  • This saving and changing a Giant has the advantage that after resuming the detachable part on a stationary part in a subsequent comparison of the filling feature stored in the removable part, the actual filling identifier, with one of the refill station when refilling the reservoir to the database transmitted amended Fill ID, the target fill ID, can be checked to see if they are the same. If this is not the case, an error has occurred, for example, the target fill ID and with it the data of the new fill of the reservoir not properly transferred to the database. Then, the controller of the dispensing machine knows that it may not use the data contained in the database (obsolete) on the drug portions contained in the reservoir.
  • the space for the stuff tag stores a bit whose value is inverted after each refill at the refill station.
  • these two possible contents of the Greets notess are sufficient for a recognition of the mere fact of refilling.
  • this simple variant is susceptible to error, so that possibly another bit (check bit) should be added redundantly.
  • a sequential number incremented at each refill i. a refill counter, to be used.
  • the fill identifier is a timestamp corresponding to the time of refill at the refill station.
  • the time stamp can simply contain a date for storage containers that can not be filled twice per day. But it can also be a time or a value of any counter that counts regardless of date and time, be included. This type of fill identifier is safer and also allows tracking a refill history.
  • the reading device associated with the stationary part comprises means for wireless communication with the information memory.
  • Such devices may be based on modulated alternating magnetic or electromagnetic fields in the low or high frequency range or optical signals. This avoids mechanical contacts between the detachable part and the stationary part and increases the reliability.
  • the wireless communication must be configured (range limiting or alternate coding) the communication processes of adjacent storage and dosing stations do not interfere.
  • the reading device associated with the stationary part may be attached to the frame or housing near the stationary part. It may also be associated with a plurality of stationary parts of a reading device. However, in a preferred embodiment, the stationary part of each supply storage and dosing station includes a reading device. This allows a spatially close arrangement of the reading device and the information memory, which reduces the power consumption during reading. If the reading device and the information memory each have receiving or transmitting devices for wireless communication, the spatially closely adjacent arrangement allows very low ranges and transmission powers, which reduces the risk of mutual interference between adjacent storage and dosing stations and energy consumption.
  • the information memory is a non-volatile semiconductor memory, for example a battery-backed RAM or - preferably - an EEPROM, for example a flash memory.
  • a non-volatile semiconductor memory for example a battery-backed RAM or - preferably - an EEPROM, for example a flash memory.
  • Such a semiconductor memory has a small size and is therefore easy to accommodate in the removable part.
  • the information memory is connected to an RFID component or contained in an RFID component.
  • the RFID device can be designed so that it does not need its own power supply, i. when reading or writing data from the reading device or the read-write device is inductively powered.
  • a preferred arrangement is characterized in that the stationary part of the supply storage and dosing station includes a first part of a dispensing device and the removable part of the storage and dosing station a second part of the dispensing device, wherein the first part of the dispensing device Drive for driving a Separating mechanism for dispensing individual medicament portions, wherein the second part of the dispensing device comprises a dispensing opening of the reservoir.
  • the first part of the dispensing device comprises a controller which is coupled to the reading device and to the control device.
  • the second part of the dispensing device contains a, adapted to the shape of the drug portions, driven by the drive separating mechanism.
  • This division of the elements of the dispensing device between the stationary and the detachable part has the advantage that elements which are adapted to the type and shape of the medicament portions can be accommodated in the detachable part having the reservoir and thus adapted to the medicament portions contained therein.
  • those elements which either require a power voltage supply (such as the drive motor) or which are in constant communication with the controller (such as the controller coupled to the reader and / or drive) are housed in the stationary part, via cable can be connected to the power supply or the control device.
  • the modified filling code could be changed at the refilling station after refilling in a separate step by means of a programmer.
  • the refill station includes a read-write device for reading information from the information store comprising identifiers of the detachable portion and for writing information comprising the fill identifier into the information store.
  • This read-write device may be arranged to communicate with the information storage of the detachable part during refilling.
  • a dispensing machine with drug portions is first removed in a step a) a demounted reservoir containing removable part of a storage storage and dosing station and transported to a refilling station.
  • the dispensing machine has a plurality of storage and dispensing stations, a packaging device that receives and dispenses drug portions dispensed from the storage and dispensing stations into dispensing packages, and a controller controlling the storage and dispensing stations and the packaging device ,
  • Each storage and dosing station comprises a stationary part and a removable part containing the refillable reservoir.
  • the detachable part has an information storage which, inter alia, stores an identifier and contains a storage space for a stuffing identifier.
  • the stationary part is associated with a reading device for reading the information memory. Before and during this removal and transport to the refill station, the space for the fill handle contains a first value.
  • the identifier is read at the refill station, the reservoir is refilled with a predetermined amount of drug portions and a second value is written into the memory location for storing the filling identifier.
  • the second value is stored together with the read identifier in a database readable by the controller.
  • This database can be arranged, for example, part of the control device or even outside of the dispensing machine.
  • step d which can be carried out, for example, after or in parallel with step c)
  • the removable part with the filled storage container is transported back to the dispensing machine and onto the stationary part of the original or another storage and dispensing station placed; then the identifier and the stuff identifier of the information store are read.
  • step e the read identifier and the read value of the Medkennung compared with the stored in the database corresponding values, wherein an error signal is generated in case of non-conformity.
  • the storage space for the filling identifier stores - in a simple embodiment - a bit whose value is inverted in step b) after each refilling at the refilling station, the resulting value being determined in step c) in the refilling station Database is stored.
  • the fill identifier is a timestamp corresponding to the time of refill at the refill station, wherein the timestamp in step b) is stored in the memory location for the pad and in step c) in the database.
  • a preferred embodiment of the method is characterized in that in step c) the filling identifier storing entry of the database is addressed by means of the read identifier. This simplifies the process and avoids additional storage of an assignment of the identifiers to the memory location addresses of the database.
  • step c) in addition to the filling identifier and information about the new contents of the reservoir, such as the number and the expiration date of the filled drug portions stored in the database. This allows an automatic adaptation of the control device of the dispensing machine available data about contained in the reservoirs drug.
  • step b) the database is looked up on the basis of the read identifier and it is determined on the basis of the information stored there which type of medicament portions are to be replenished.
  • a refill reservoir prior to refilling in step b), a refill reservoir is provided, an identifier attached to this refill reservoir is read, and read from the refill reservoir identifier and read from the refill reservoir Information store of the removable part read identifier determines whether the refill reservoir contains the correct nachzu Jewishden drug portions.
  • this refill reservoir identifier may be in the form of a bar code, and the identifier may be read by means of a scanner, for example. This procedure improves the safety of a correct filling of the reservoir.
  • FIGS. 2 to 4 is a dispenser 1 shown schematically in the patent application EP 12 182 634.1 (not yet published) is described and used in the inventive arrangement or with the aid of the inventive method can be performed. It should be noted at this point, however, that the arrangement according to the invention and the method according to the invention can also be carried out with a multitude of differently designed dispensing machines.
  • the dispenser 1 according to FIG. 2 has a plurality of in a plane next to and above each other in rows and columns arranged storage and dosing stations 2, one of which in FIG. 4 is shown.
  • a storage and dosing station 2 comprises a fixed part 4 fixed to a frame 8 and a detachable part 3 mounted thereon.
  • the removable part 3 contains a reservoir 5 for a plurality of identical drug portions, such as tablets or capsules.
  • the storage-and-dosing station 2 includes a dispensing device, with the help of each individual drug portions removed from the reservoir 5 and via a containing in the stationary part 4 guide shaft at the in FIG.
  • each storage-and-dosing station 2 has within its stationary part 4 a connected to the central control device 9 of the dispensing machine 1 controller, which in turn drives a drive motor of a separating mechanism, provided that the central control device 9, the delivery of a drug portion of the associated reservoir 5 requests.
  • the separating mechanism not described in detail here comprises, in addition to the controller and the drive in the stationary part 4, a separating mechanism driven by the drive and contained in the detachable part 3, which is adapted to the respective shape of the medicament portions contained in the reservoir 5.
  • the separating mechanism comprises a so-called separating wheel, ie a rotating cylinder with adapted to the diameter of the drug portions vertical guide channels, each of which can receive a drug portion at its upper end by a predetermined opening of the reservoir 5 and at its lower end to a rotationally offset to the opening Position the drug portion contained in the guide channel can pass on to an opening to the stationary part 4, so that the drug delivered to the stationary part portion moves through an inclined guide shaft and then at the Outlet opening of the stationary part 4 is discharged.
  • the guide well through which the drug portion moves is optionally monitored by a sensor to detect the passage of the drug portion. This sensor portion detecting sensor is in turn coupled to the controller of the stationary part 4.
  • a vertical column of stacked storage storage and dosing stations 2 can be coupled to a vertical chute 32 such that in FIG. 3 arranged on the right (not visible) inlet openings of the chute 32 with associated outlet openings of the stationary part 4 of the storage and dosing stations 2 are coupled such that emerge from the storage and dosing stations 2 leaking drug portions in the chute 32. Therein they fall vertically downwards, with the inner walls of protruding inwards into the chute protrusions 33 dampen the case by laterally deflect the movement of the falling drug portions. When the drug portions falling in the chute 32 reach the bottom of the chute 32, they exit the chute 32 and fall into a collection container 40.
  • Collective containers 40 generally collect multiple drug portions which together are dispensed into a dispensing package to be manufactured by the dispensing machine are to bring.
  • the collecting containers 40 are purposefully emptied at the packaging device 30 such that the medicament portions exiting from the collecting containers 40 fall into a still open pocket of a dispensing package provided below, after which the pocket or the dispensing package is closed.
  • dispensing move the vertical chutes 32 on the matrix of the storage and dosing stations 2 in the horizontal direction over, so that the inlet openings of the chutes 32 successively with the outlet openings of in a series of horizontally juxtaposed storage storage and dosing stations 2 are connected.
  • these are connected at their top and bottom with each in a horizontal plane circulating conveyor belts 31a, 31b, wherein the conveyor belts 31a, 31b are guided around drive wheels 34.
  • the drive wheels 34 are in turn mounted on a driven by a drive motor 36 shaft 35.
  • Both conveyor belts 31a and 31b have mounting lugs 37 at equidistant intervals, to which the chutes 32 are fastened.
  • FIG. 2 For the sake of clarity, only one vertical chute 32 is shown.
  • the conveyor belts 31a and 31b circumferentially fully equipped with chutes 32.
  • Below the horizontal circumferential chutes 32 another conveyor belt 38 is guided by drive wheels, which moves at the same speed as the conveyor belts 31a, 31b.
  • On the conveyor belt 38 are - also at equidistant intervals - mounting lugs 39, wherein the distance corresponds to that of the mounting lugs 37.
  • the collecting container 40 On the mounting bosses 39, the collecting container 40 are mounted, wherein in FIG.
  • FIG. 2 again, by way of example only, six such collection containers 40 are shown.
  • the entire conveyor belt 38 is circumferentially equipped with storage containers 40.
  • the distances between the collection containers correspond to the distances between the chutes.
  • 32 collectively associated containers 40 are moved along at the lower ends of the chutes.
  • the collecting container 40 leave the position of the running chutes 32, because the conveyor belt 38 is led beyond the region of the conveyor belts 31a, 31b, as in the left front area of FIG. 2 can be seen.
  • the collection container 40 are then passed over the packaging device 30 and successively into corresponding initially still open top dispensing packages discharged.
  • the dispensing packs are made of weldable plastic films.
  • FIG. 2 and FIG. 3 is an endless foil strip 41 to recognize, which is the packaging device 30 is supplied (for example, from a roll of film).
  • FIG. 3 bottom left, a housing of the central control device 9 is shown schematically. About (not shown) line connections, this control device 9 is connected to both the packaging device 30 and with all the drive motors and all storage and dosing stations 2. In addition, the control device is connected to all the operation of the Dispensierautomaten monitoring sensors.
  • FIG. 4 shows the storage-and-dosing station 2 in the state in which the detachable part 3 is seated on the stationary part 4.
  • a vertical handle of the removable part 3 At the lower end of the handle, an RFID component with an information storage 6 is preferably introduced, which is arranged wirelessly with a reading device 6 introduced into the stationary part 4 adjacent to the handle.
  • the reading device 7 can read the information memory 6. The read data first go to the controller within the stationary part 4 and from there to the central control device 9.
  • the information storage 6 stores according to the invention, inter alia, an identifier of the removable part 3 and a Medkennung, preferably in the form of a time stamp, which marks the time of refilling.
  • FIG. 1 the arrangement according to the invention is shown schematically.
  • the inventive arrangement has a refill station 10.
  • the refill station 10 At the refilling station 10 in the course of operation emptied reservoir of a removed removable part 3 of a storage and dosing station 2, each with a predetermined amount of drug portions of the same type and size filled.
  • the refill station 10 includes a read and write device 11 which can communicate with the information storage of a replenished on the refill station 10 detachable part 3 of a storage and dosing station 2 such that they can write a new Grekennung in the information memory.
  • the filling code is changed at the refill station 10, preferably a time stamp of refilling inscribed in the information memory 6.
  • the refill station 10 has a controller 12 which is connected to the reading and writing device 11.
  • the refill station 10 may also include a scale with which the weight of the detachable part 4 can be continuously determined, so that the refilling of the correct number of medicament portions (with known individual weight) can be checked.
  • both the controller 9 of the dispensing machine 1 and the controller 12 of the refill station 10 is coupled to a database 13.
  • the database 13 stores for each detachable part 3 of a storage and dosing station 2 at least one record, in addition to the identifier of the removable part 3 and the filling identifier (time stamp) information about the contents of the reservoir 5, such as the number, Art and the expiration date of the medicine portions.
  • the control device 9 of the dispensing machine 1 can access the data records of the database 13 in order to determine, when the dispensing of a specific medication portion in a certain dispensing package is requested, by looking up in the database 13 to determine which storage-and-dispensing station 2 activate is.
  • the procedure is as follows. First, it is assumed that the information memory 6 of a detachable part 3 of a storage-and-dosing station 2 whose reservoir 5 is empty stores an identifier ID of the detachable part 3 and a time stamp TS1 of the earlier refilling. This removable part 3 is now removed and moved to the refilling station 10, which is indicated by the arrow 20. In addition to the arrow 20, the designation ID + TS1 indicates that the information store 6 contains the old time stamp TS1 in addition to the identifier ID.
  • the controller 12 of the refill station 10 causes a read of the information memory 6 by means of the read and write device 11. With the aid of the read identifier ID, the refill station 10 beats in the database 13 and thus determines the type of drug portions to be replenished.
  • An in FIG. 1 Unillustrated refill reservoir is brought to the refill station 10 where an identifier attached to the refill reservoir is read. On the basis of the read information of the refill reservoir and retrieved from the database 13 information is checked whether the refill reservoir contains the correct nachzu religiousden drug portions. If this is the case, the reservoir 5 is refilled from the refill reservoir.
  • the controller 12 of the refill station 10 causes its writing device 11 to write a new time stamp as a stuffing identifier into the information store 6 of the detachable part 3. This is in FIG. 1 illustrated by the arrow 21.
  • the controller 12 causes the new Grewung, ie the new Timestamp TS2 is written to the database 13 in association with the identifier ID.
  • further information about the replenished drug portions is stored in the database 13. This is indicated by the arrow 22 in FIG FIG. 1 illustrated.
  • the newly filled removable part 3 is again placed on its stationary part 4 of the storage and dosing station 2, where it now contains in its information memory 6 the identifier ID together with the new time stamp TS2.
  • the controller 9 causes reading of the information memory 6 by the reading device 7 of the stationary part 4.
  • This reading of the identifier and the new time stamp (ID + TS2) is illustrated by the arrow 24.
  • the control device 9 reads from the data record of the database 13 addressed with the identifier ID the time stamp stored there, which would have to be the new time stamp TS2 if the data were correctly transmitted. This is illustrated by the arrow 25.
  • the controller 9 compares the identifiers and the timestamps, generating an error signal if they do not match.
  • An operator of the device is sent a message that either the database 13 or the newly attached detachable part 3 does not have the required correct timestamp. Subsequently, it can be checked whether there was a lack of correct transmission of the data from the filling station 10 to the database 13, or whether other errors have occurred. As long as the errors have not been eliminated, the affected storage-and-dosing station 2 is deactivated, ie an output of drug portions from this station is suppressed.

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Quality & Reliability (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Basic Packing Technique (AREA)

Claims (18)

  1. Agencement destiné à emballer des portions de médicaments dans des emballages distributeurs, constitué d'un dispensateur automatique (1) et d'au moins un poste de réapprovisionnement (10),
    le dispensateur automatique (1) comportant une pluralité de postes de stock de réserve et de dosage (2) qui reçoivent chacun une pluralité de portions de médicaments et sont susceptibles de les distribuer une à une, un dispositif d'emballage qui réceptionne les portions de médicaments distribuées par les postes de stock de réserve et de dosage et les introduit dans des emballages distributeurs et un dispositif de commande (9) commandant les postes de stock de réserve et de dosage et le dispositif d'emballage,
    chaque poste de stock de réserve et de dosage (2) comprenant une partie (4) stationnaire fixée sur un cadre (8) ou un boîtier du dispensateur automatique (1) et une partie (3) amovible contenant un conteneur de réserve (5) rechargeable pour des portions de médicaments, la partie (3) amovible comportant une mémoire d'informations (6) qui mémorise entre autres un identifiant de la partie amovible, et à la partie (4) stationnaire étant associé un dispositif de lecture (7) destiné à lire la mémoire d'informations (6),
    l'au moins un poste de réapprovisionnement (10) servant à recharger avec des portions de médicaments le conteneur de réserve (5) d'une partie (3) amovible retirée du poste de stock de réserve et de dosage (2),
    chaque mémoire d'informations (6) contenant une emplacement de mémoire pour une caractéristique de remplissage (TS1, TS2), chaque fois que le conteneur de réserve (5) vient d'être réapprovisionné, la caractéristique de remplissage étant modifiée sur le poste de réapprovisionnement (10) de telle sorte qu'à la lecture de la mémoire d'informations (6) par le dispositif de lecture (7), une fois que la partie (3) amovible a été replacée sur la partie stationnaire (4), la recharge de cette dernière ou d'un autre poste de stock de réserve et de dosage (2) puisse être reconnue par le dispositif de commande (9),
    le poste de réapprovisionnement (10) étant couplé avec une base de données (13) et lisant l'identifiant (ID) de la partie amovible réapprovisionnée et le mémorisant dans la base de données (13), en commun avec la caractéristique de remplissage (TS2) modifiée et
    le dispositif de commande (9) du dispensateur automatique (1) étant configuré de sorte à pouvoir
    réceptionner de la part des dispositifs de lecture (7) des postes de stock de réserve et de dosage (2) les identifiants (ID) lus avec les caractéristiques de remplissage (TS1, TS2) correspondantes des parties amovibles (3) replacées,
    lire dans la base de données (13) la caractéristique de remplissage mémorisée en commun avec un identifiant et
    comparer l'identifiant (ID) lu et la caractéristique de remplissage (TS1, TS2) lue d'une partie amovible (3) replacée avec les valeurs correspondantes dans la base de données (13) et générer un signal de défaut, en cas de non-concordance.
  2. Agencement selon la revendication 1, caractérisé en ce que l'emplacement de mémoire pour la caractéristique de remplissage (TS1, TS2) mémorise un bit dont la valeur est inversée sur le poste de réapprovisionnement (10), après chaque recharge.
  3. Agencement selon la revendication 1, caractérisé en ce que la caractéristique de remplissage est un horodateur (TS1, TS2) qui correspond à l'instant de recharge sur le poste de réapprovisionnement (10).
  4. Agencement selon l'une quelconque des revendications 1 à 3, caractérisé en ce que le dispositif de lecture (7) associé à la partie (4) stationnaire comporte des systèmes pour la communication sans fil avec la mémoire d'informations (6).
  5. Agencement selon l'une quelconque des revendications 1 à 4, caractérisé en ce que la partie (4) stationnaire de chaque poste de stock de réserve et de dosage (2) contient un dispositif de lecture (7).
  6. Agencement selon l'une quelconque des revendications 1 à 5, caractérisé en ce que la mémoire d'informations (6) est une mémoire non volatile à semi-conducteur.
  7. Agencement selon l'une quelconque des revendications 1 à 6, caractérisé en ce que la mémoire d'informations (6) est contenue dans un composant RFID.
  8. Agencement selon l'une quelconque des revendications 1 à 7, caractérisé en ce que la partie (4) stationnaire du poste de stock de réserve et de dosage (2) contient une première partie d'un dispositif dispensateur et la partie amovible (3) du poste de stock de réserve et de dosage (2) contient une deuxième partie du dispositif dispensateur, la première partie du dispositif dispensateur contenant un entraînement destiné à entraîner un mécanisme de désolidarisation pour distribuer des portions individuelles de médicaments, la deuxième partie du dispositif dispensateur comprenant un orifice de distribution du conteneur de réserve (5).
  9. Agencement selon la revendication 8, caractérisé en ce que la première partie du dispositif dispensateur comprend un contrôleur qui est couplé avec le dispositif de réserve (7) et avec le dispositif de commande (9).
  10. Agencement selon la revendication 8 ou la revendication 9, caractérisé en ce que la deuxième partie du dispositif dispensateur contient un mécanisme de désolidarisation adapté à la forme des portions de médicaments, entraîné par l'entraînement.
  11. Agencement selon l'une quelconque des revendications 1 à 10, caractérisé en ce que le poste de réapprovisionnement (10) comporte un dispositif de lecture-écriture destiné (11) à lire dans la mémoire d'informations (6) des informations comprenant l'identifiant de la partie (3) amovible et à écrire dans la mémoire d'informations (6) des informations comprenant la caractéristique de remplissage.
  12. Procédé destiné à réapprovisionner avec des portions de médicaments un conteneur de réserve d'un poste de stock de réserve et de dosage d'un dispensateur automatique, le dispensateur automatique comportant une pluralité de postes de stock de réserve et de dosage, un dispositif d'emballage qui réceptionne les portions de médicaments distribuées par les postes de stock de réserve et de dosage et les introduit dans des emballages distributeurs et un dispositif de commande qui commande les postes de stock de réserve et de dosage et le dispositif d'emballage, chaque poste de stock de réserve et de dosage comprenant une partie stationnaire et une partie amovible contenant le conteneur de réserve rechargeable, la partie amovible comportant une mémoire d'informations qui mémorise entre autres un identifiant (ID) et qui contient un emplacement de mémoire pour une caractéristique de remplissage et à la partie stationnaire étant associé un dispositif de lecture destiné à lire la mémoire d'informations, :
    a) une partie amovible contenant le conteneur de réserve vide étant retirée de l'un des postes de stock de réserve et de dosage, l'emplacement de mémoire pour la caractéristique de remplissage contenant une première valeur (TS1) et la partie amovible étant transportée (20) vers un poste de réapprovisionnement,
    b) au poste de réapprovisionnement, l'identifiant (ID) étant lu, le conteneur de réserve étant rechargé avec une quantité prédéfinie de portions de médicaments et dans l'emplacement de mémoire destiné à mémoriser la caractéristique de remplissage étant inscrite (21) une deuxième valeur (TS2),
    c) la deuxième valeur (TS2) étant mémorisée (22) avec l'identifiant (ID) lu dans une base de données lisible par le dispositif de commande,
    d) la partie amovible avec le contenant de réserve étant retransportée (23) vers le dispensateur automatique et étant placée sur la partie stationnaire du poste de stock de réserve et de dosage initial ou d'un autre et l'identifiant (ID) et la caractéristique de remplissage (TS2) de la mémoire d'informations étant lus (24),
    e) l'identifiant (ID) lu et la valeur lue de la caractéristique de remplissage (TS2) étant comparés avec les valeurs correspondantes mémorisées dans la base de données, en cas de non-concordance, un signal de défaut étant généré.
  13. Procédé selon la revendication 12, caractérisé en ce que l'emplacement de mémoire pour la caractéristique de remplissage mémorise un bit dont la valeur est inversée dans l'étape b), après chaque recharge au poste de réapprovisionnement, la valeur résultante étant mémorisée dans la base de données dans l'étape c).
  14. Procédé selon la revendication 12, caractérisé en ce que la caractéristique de remplissage est un horodateur qui correspond à l'instant de la recharge au poste de réapprovisionnement, l'horodateur étant mémorisé dans l'emplacement de mémoire pour la caractéristique de remplissage dans l'étape b) et dans la base de données dans l'étape c).
  15. Procédé selon l'une quelconque des revendications 12 à 14, caractérisé en ce que l'inscription dans la base de données mémorisant la caractéristique de remplissage est adressée au moyen de l'identifiant lu.
  16. Procédé selon l'une quelconque des revendications 12 à 15, caractérisé en ce que dans l'étape c), parallèlement à la caractéristique de remplissage, également des mentions concernant le nouveau contenu du conteneur de réserve, comme par exemple le nombre et la date de péremption des portions de médicaments chargées sont mémorisées dans la base de données.
  17. Procédé selon l'une quelconque des revendications 12 à 16, caractérisé en ce que dans l'étape b), à l'aide de l'identifiant lu dans la base de données, il est cherché et à l'aide des informations qui y sont mémorisées, il est déterminé quel type des portions de médicaments doivent être réapprovisionnés.
  18. Procédé selon l'une quelconque des revendications 12 à 17, caractérisé en ce qu'avant le réapprovisionnement dans l'étape b), un conteneur de réserve de réapprovisionnement est mis à disposition, un identifiant appliqué sur ledit conteneur de réserve de réapprovisionnement est lu et à l'aide de l'identifiant du conteneur de réserve de réapprovisionnement et de l'identifiant lu dans la mémoire d'informations de la partie amovible, il est déterminé si le conteneur de réserve de réapprovisionnement contient les portions correctes de médicaments à réapprovisionner.
EP13181201.8A 2013-08-21 2013-08-21 Agencement pour l'emballage de portions de médicaments dans des emballages de distribution et procédé de re-remplissage d'un récipient de stockage d'une station de stockage et de dosage d'un distributeur automatique en portions de médicaments Active EP2840026B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
EP13181201.8A EP2840026B1 (fr) 2013-08-21 2013-08-21 Agencement pour l'emballage de portions de médicaments dans des emballages de distribution et procédé de re-remplissage d'un récipient de stockage d'une station de stockage et de dosage d'un distributeur automatique en portions de médicaments
ES13181201.8T ES2581517T3 (es) 2013-08-21 2013-08-21 Disposición para envasar porciones de medicamentos en envases de entrega y procedimiento para rellenar un contenedor de almacenaje de una estación de almacenamiento de existencias y dosificación de un dispensador automático con porciones de medicamentos
PT131812018T PT2840026T (pt) 2013-08-21 2013-08-21 Montagem para acondicionamento de doses individuais de medicamentos em embalagens de fornecimento, e procedimento para recarga com doses individuais de medicamentos de um recipiente de armazenamento de um posto de memorização de stock e de doseamento integrado num autómato de distribuição
DK13181201.8T DK2840026T3 (en) 2013-08-21 2013-08-21 Device for packing drug portions in dispensing packages and method for refilling a storage container of a storage and dispensing station of an automatic dispensing machine with drug portions
US14/912,817 US10307338B2 (en) 2013-08-21 2014-08-05 Assembly for packaging drug portions in dispensation packs and method for refilling a reservoir of a storing and metering station of a dispensing machine with drug portions
PCT/EP2014/066815 WO2015024771A1 (fr) 2013-08-21 2014-08-05 Ensemble permettant l'emballage de portions de médicaments dans des emballages distributeurs et procédé permettant le nouveau remplissage d'un réservoir de stockage d'une station de stockage et de dosage d'un distributeur automatique en portions de médicaments
CN201480046590.XA CN105492325B (zh) 2013-08-21 2014-08-05 在投递包中包装药物部的设备和对分配机的贮存和计量站的贮存容器再填充药物部的方法
US16/393,782 US11039984B2 (en) 2013-08-21 2019-04-24 Assembly for packaging drug portions in dispensation packs and method for refilling a reservoir of a storing and metering station of a dispensing machine with drug portions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13181201.8A EP2840026B1 (fr) 2013-08-21 2013-08-21 Agencement pour l'emballage de portions de médicaments dans des emballages de distribution et procédé de re-remplissage d'un récipient de stockage d'une station de stockage et de dosage d'un distributeur automatique en portions de médicaments

Publications (2)

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EP2840026A1 EP2840026A1 (fr) 2015-02-25
EP2840026B1 true EP2840026B1 (fr) 2016-04-27

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EP13181201.8A Active EP2840026B1 (fr) 2013-08-21 2013-08-21 Agencement pour l'emballage de portions de médicaments dans des emballages de distribution et procédé de re-remplissage d'un récipient de stockage d'une station de stockage et de dosage d'un distributeur automatique en portions de médicaments

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US (2) US10307338B2 (fr)
EP (1) EP2840026B1 (fr)
CN (1) CN105492325B (fr)
DK (1) DK2840026T3 (fr)
ES (1) ES2581517T3 (fr)
PT (1) PT2840026T (fr)
WO (1) WO2015024771A1 (fr)

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CA2931195C (fr) 2013-11-25 2019-09-24 Icu Medical, Inc. Procedes et systeme pour remplir des sacs pour perfusion intraveineuse d'un fluide therapeutique
JP6710758B2 (ja) 2015-12-04 2020-06-17 アイシーユー・メディカル・インコーポレーテッド 医療用流体を移送するための電子式医療用流体移送装置
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CA3031529A1 (fr) 2016-07-25 2018-02-01 Icu Medical, Inc. Systemes, procedes et composants pour pieger des bulles d'air dans des modules et des systemes de transfert de fluide medical.
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US11039984B2 (en) 2021-06-22
US20190247280A1 (en) 2019-08-15
WO2015024771A1 (fr) 2015-02-26
US10307338B2 (en) 2019-06-04
CN105492325B (zh) 2018-02-23
ES2581517T3 (es) 2016-09-06
US20160193114A1 (en) 2016-07-07
CN105492325A (zh) 2016-04-13
DK2840026T3 (en) 2016-07-25
PT2840026T (pt) 2016-07-13
EP2840026A1 (fr) 2015-02-25

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