EP2754615B1 - Installation destinée au garnissage pour une personne de blisters avec des médicaments selon des informations de prescription prédéfinies - Google Patents

Installation destinée au garnissage pour une personne de blisters avec des médicaments selon des informations de prescription prédéfinies Download PDF

Info

Publication number
EP2754615B1
EP2754615B1 EP13151166.9A EP13151166A EP2754615B1 EP 2754615 B1 EP2754615 B1 EP 2754615B1 EP 13151166 A EP13151166 A EP 13151166A EP 2754615 B1 EP2754615 B1 EP 2754615B1
Authority
EP
European Patent Office
Prior art keywords
medicament
metering
blister
compartments
magazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP13151166.9A
Other languages
German (de)
English (en)
Other versions
EP2754615A1 (fr
Inventor
Edwin Kohl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to EP13151166.9A priority Critical patent/EP2754615B1/fr
Priority to PCT/EP2014/050151 priority patent/WO2014108402A1/fr
Priority to US14/760,593 priority patent/US20150353213A1/en
Priority to CA2897748A priority patent/CA2897748A1/fr
Priority to CN201480004827.8A priority patent/CN104918856B/zh
Publication of EP2754615A1 publication Critical patent/EP2754615A1/fr
Application granted granted Critical
Publication of EP2754615B1 publication Critical patent/EP2754615B1/fr
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B69/00Unpacking of articles or materials, not otherwise provided for
    • B65B69/005Unpacking of articles or materials, not otherwise provided for by expelling contents, e.g. by squeezing the container
    • B65B69/0058Solid contents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B5/10Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles
    • B65B5/101Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity
    • B65B5/103Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity for packaging pills or tablets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B57/00Automatic control, checking, warning, or safety devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B57/00Automatic control, checking, warning, or safety devices
    • B65B57/10Automatic control, checking, warning, or safety devices responsive to absence, presence, abnormal feed, or misplacement of articles or materials to be packaged
    • B65B57/14Automatic control, checking, warning, or safety devices responsive to absence, presence, abnormal feed, or misplacement of articles or materials to be packaged and operating to control, or stop, the feed of articles or material to be packaged
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B61/00Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
    • B65B61/20Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for adding cards, coupons or other inserts to package contents
    • B65B61/202Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for adding cards, coupons or other inserts to package contents for attaching articles to the outside of a container

Definitions

  • the invention relates to a system for personal placement of Be Schollblistern with drugs according to predetermined prescription data, the Be Schollblister in a matrix configuration in rows corresponding to a number of times during a day and columns corresponding to a number of days, such as days of the week, arranged receiving compartments for respective drug administration units exhibit.
  • From the DE 10 2004 034 024 A2 is an individual blister pack for the weekly drug needs of a patient (weekly blister) known to take the medication in a order by date, day of the week and time of day (morning, noon and evening and / or night) ordered.
  • the receiving compartments of the blister pack for receiving the respective medicaments are arranged in matrix form and with seven daily columns, each with at least three time of day compartments, which are closed overall by a continuous blister foil.
  • Affixed to the blister pack is a carton-shaped lid, on which the patient-specific the composition of the individual time of day subjects as well as prescription information concerning the respective medicaments is contained.
  • Such weekly blister packs are for patients who regularly need to take several different drugs, a help not only to remember the intake of important medications and on the other hand to keep a reliable overview of what medications are already taken to avoid a potentially harmful over-medication ,
  • WO 2005 102 841 A1 is a system for equipping such patient-specific blister packs with the desired drug composition known.
  • a dispensing station For each drug, a dispensing station is provided which conveys the medicaments from a temporary package in the form of a strip blister into the corresponding receiving compartments of the packaging unit by spatulas associated with the receiving compartments of the blister pack. All patient-specific blister packs cyclically pass through all the dispensing stations of the system, whereby only at those stations medications are taken which correspond to the prescription data associated with the individual blister pack. In this way, patient-specific packaging units can be filled automatically and safely with a selection of several hundred drugs.
  • WO 2009/023632 is a system for person-specific placement of drug packages known, which pass through a plurality of filling stations for each drug, in which filling the medication from a reservoir initially transferred to a movable transfer slide and then filled into the drug packages.
  • the object is achieved by a system for personal placement of Be Schollblistern with drugs according to prescribed prescription data, the Be Stirllblister in a matrix configuration in rows corresponding to a number of times during a day and columns corresponding to a number of days, such as days of the week, arranged receiving compartments for respective drugs
  • Administering units comprising a plurality of successively arranged drug filling stations for loading the Be Stirllblister each with a particular drug, and a transport device configured to transport the Be colllblister individually in a row in a direction of movement along the drug filling stations each drug filling station movable between two positions Vordosiermagazin with several Vordosierfumbleern has, which is adapted to the drug in a first position in a or to receive in a second position, the drug from the Vordosierfownern in corresponding receiving compartments of the Be colllblisters, characterized in that in each drug filling station (40) the drug by means of a strip blister (45) supplied, and each
  • each drug filling station the medicament is delivered by means of a strip blister, each medicament filling station having one or more ejector plungers for expelling the drug from blister stations of the strip blister into the pre-metering compartments of the pre-metering magazine.
  • each medicament filling station having one or more ejector plungers for expelling the drug from blister stations of the strip blister into the pre-metering compartments of the pre-metering magazine.
  • the pre-metering preferably has a in the second position of the same displaceable in the transverse direction bottom, which ensures a fast and safe transfer of medication into the receiving compartments of the Be colllblisters.
  • the pre-metering compartments of the pre-metering magazine are preferably designed in a row such that they are arranged in the second position in each case over the receiving compartments of the filling blister arranged in a row corresponding to a number of (week) days.
  • Each medication filling station preferably has at least one sensor device for checking the correct intake of the medicament into the pre-metering compartments of the pre-metering magazine and / or the correct delivery of the medicament into the receiving compartments of the filling blister.
  • the pre-metering magazine in the region of the rest position of a drug in the Vordosierfumbleern have laterally arranged slots, wherein a first sensor device is designed to detect optically through the slots a drug in the Vordosierfumbleern during a movement of the pre-metering magazine from the first to the second position and vice versa ,
  • the bottom of the pre-metering compartments of the pre-metering magazine can be translucent or light-reflecting, and a second sensor device can comprise a camera for detecting medicaments located on the bottom of the predispersing compartments.
  • filling errors can be reliably, reliably and quickly detected, and incorrectly filled filling blisters can then be reliably sorted out in a separate method step.
  • the pre-metering magazine may have a replaceable plastic inner lining for cleaning purposes.
  • the Be Schollblister are driven by a magnetic path with a linear motor, whereby an individual control and reliable transport of a variety of Be colllblistern is possible.
  • workpiece carriers guided in a magnetic rail are provided for receiving the filling blister, which workpiece carriers are conveyed in a closed circuit, wherein the Be colllblister be placed on the workpiece carrier before assembly and removed again after the assembly process.
  • the system according to the invention may further comprise a camera arranged above the transport device for optically checking the correct placement of the filling blister in accordance with the prescription data.
  • the pre-metering magazine can be freely accessible for manual delivery of a drug. As a result, drugs that are rarely needed can be delivered manually or with other delivery techniques without sacrificing system performance.
  • the method according to the invention preferably has the method step of creating and attaching a documentation carrier to the filling blister comprising personal information and / or application information to the medicaments packed in the filling blister.
  • FIG. 1 shows in a schematic plan view of a filling module 41 of an embodiment of the inventive system for personal placement of Be Schollblistern 25.
  • Be Schollmodul 41 consists in the illustrated embodiment of five consecutively arranged drug filling stations 40, which are each provided for dispensing of dosage units of a particular type of drug.
  • the number of summarized in a Be Shellmodul 41 medication filling stations 40 is of course not limited to five, but can be selected depending on space or convenience.
  • the total number of drug filling modules 41 of the plant is not limited to a certain number. In principle, the total number of filling stations 40 determines the maximum number of medicaments that can be blistered with the system, and more than one filling station can be provided for particularly frequently used medicaments.
  • FIG. 2a shows an embodiment of a Be Schollblisters 25 for use with the inventive plant in perspective view and the FIGS. 2b and 2c in cross-sectional view with or without blister foil 27.
  • the Be Schollblister 25 arranged in matrix configuration receptacles 26, which are arranged in the illustrated embodiment in four lines corresponding to a number of intake times during a day (morning, noon, evening, night) and seven columns corresponding to the days of a week.
  • the invention is not limited to this particular arrangement of the receiving compartments 26 of the Be colllblisters.
  • FIG. 1 shows this designed as a magnetic rail guide rail 11 for transporting the Be Schollblister 25, the case on a workpiece carrier 20 (shown schematically in FIG FIG. 6 ) rest.
  • the workpiece carrier 20 is preferably provided with depressions (not shown) corresponding to the arrangement of the receiving compartments 26 of the filling blister 25.
  • a Be Valllblister 25 stops at three to seven filling stations, where the respective drug by means of a pre-metering magazine 50 is supplied in rows, as with reference to the FIGS. 3 to 6 will be explained in detail later.
  • a clean room area is planned, which in FIG. 1 schematically designated 30.
  • germ-free and particle-poor air is blown down from the ceiling in this clean room area 30, which prevents germs or undesired dust particles from entering the opened filling blister 25.
  • a phototunnel 32 with a (not shown) camera is provided, which creates an optical image of the Be colllblisters 25 after passing through the previous Be Colllmoduls 41.
  • an evaluation electronics system can check whether the drug equipment was correctly executed in accordance with the respective patient prescription data.
  • FIG. 4 illustrated schematically in plan and FIG. 6 In a cross-sectional view of the drug filling process at a drug filling station 40.
  • the filling module 25 by means of the workpiece carrier 20 to the provided Drug filling module 40 transported.
  • the Be Glallmodul 20 stops its movement and the pre-metering magazine 50 performs a movement perpendicular to the direction of movement of the Be colllblister, as in the Figures 6a and 6b indicated by an arrow.
  • At the end of this transverse movement is in each case a predispensing compartment 51 over a weekday compartment 26 of a line of the Be colllblisters 25 (FIG. FIG. 3a and FIG. 6c ).
  • an opening mechanism of the pre-metering pockets 51 of the pre-metering magazine 50 is activated, so that the medicaments located in the pre-metering compartments 51 drop into the corresponding compartments 26 of the filling blister 25 at a low drop height.
  • the opening mechanism of the pre-metering magazine is formed in the illustrated embodiment of the invention as a displaceable bottom 55 of the pre-metering magazine.
  • other mechanisms such as folding mechanisms or the like are also possible within the scope of the invention.
  • the filling blister 25 is transported further in the corresponding number of lines and the pre-metering magazine 50 moves backward (FIG. 3d figure and FIG. 6d ), is provided with a new portioning of the drugs, which are then filled in the same manner in the other time line of the Be colllblisters 25.
  • the Be Colllblister 25 moves to the next scheduled drug filling station 40th
  • FIG. 4 An embodiment of a pre-metering magazine 50 is shown in schematic perspective view in FIG FIG. 4 shown.
  • the predosing compartments 51 are in the form of a transparent plastic inner lining, which can be exchanged for cleaning purposes and can be fastened to a stable frame part 54, which is preferably made of metal.
  • Slots 52 are provided on both sides in the lower region of the side walls of the predatory bins 51 for optically checking whether a medicament is or not present in the respective predosing bins.
  • the mechanism for delivering the medication 28 into the pre-metering magazine 50 of a drug delivery station 40 is shown schematically in FIG FIG. 5 shown.
  • the medicament is supplied by means of an endless strip blister 45 which has equidistantly arranged blister stalls 46 for receiving the medicament dosages, wherein the spacing of the individual blister stalls 46 of the strip blister 45 from one another can correspond to the distance of the predispersing compartments 51 of the predosing magazines 50.
  • the strip blister 45 located in the respective medication filling stations 40 is preferably unrolled from a roll known per se with the aid of a drive mechanism (not shown).
  • a strip blister 45 is used up, then a new, filled strip blister roll can be hung without difficulty in the medication filling station 40 and / or the new strip blister can be glued or adhered directly to the existing strip blister, so that an uninterrupted supply of medicaments is ensured.
  • at least one medication filling station 40 for manual filling of the pre-metering magazine 50 may be provided. This makes it possible to increase the flexibility of the plant and to include very rarely prescribed drugs on economic conditions in the blistering.
  • Each medication filling station 40 has ejector plungers 42 for ejecting medicaments 28 from strip blister 45 into pre-metering magazine 50.
  • ejection plungers 42 are provided in a number corresponding to the number of predosounders 51 of predosing magazine 50 for time-saving parallel ejection of the medicament units; However, this is not absolutely necessary, but a sequential ejection of the drugs is also possible.
  • a medication filling station 40 has at least two sensor devices 47, 48 for checking the correct transfer of medication to the blister pre-metering magazine filling blister.
  • a first transmitted light camera or Photocell 47 detects, by means of the slits 52 provided on the predispersing compartments 51, whether there is a medicament in the corresponding predosing compartment 51 during the extension movement of the predosing magazine 50 and if it no longer lies therein during the later retracting movement, whereby the correct dispensing of the medicament units into the predispersing compartment corresponding compartments of the Be colllblisters can be validated.
  • an incident-light camera 48 is preferably provided, which also optically validates the filling state of the predosing compartments 51 before the medicament is transferred to the filling blister and then either by means of light reflection or as a transmitted-light detector.
  • the bottom of the pre-metering magazine 50 must be translucent.
  • the use of the pre-metering magazine 50 in the placement system according to the invention ensures that the ejection process from the strip blister 45 and the loading process of the Behellblisters 25 are decoupled from each other.
  • the time-critical filling process of the filling blister 25 with respect to speed can be optimized for the performance of the overall system, while more time is available for the mechanically difficult ejection process from the strip blister 45 without impairing the performance of the overall system.
  • a magnetic rail system 10 is provided with linear motor drive, which allows each workpiece carrier 20 and thus the Be Glallblister 25 located thereon to control individually.
  • the magnetic track system 10 has a self-contained guide rail 11, which in cross-sectional view in FIG. 6 is shown.
  • Each workpiece carrier 20 has a guide element 12, which surrounds the guide rail 11 and is guided in a known manner according to the principle of a magnetic levitation train contactless or touching (sliding, rolling) in the guide rail 11.
  • An electric linear motor which is also known per se, provides the individually controllable drive of the workpiece carriers 20 and thus the filling blister 25.
  • a Be Schollblister-supporting station 60 is provided which in FIG. 8 is indicated schematically.
  • a Be Schollblister removal station 61 is arranged accordingly.
  • a first method step S2 ( FIG. 7 ) an empty Be colllblister 25 is thus placed on the workpiece carrier 20 in the Be Schollblister-Avemlagestation 60.
  • the filling stations to be approached are determined in method step S4, in which in FIG. 8 shown embodiment, these are the stations A, B and C.
  • For the considered Be Shellblister 25 is now checked in step S6, whether the transport path to the next to be approached filling station is occupied by a at an intermediate filling station in a filling process involved Be clergyden Be spallblister or not. If this is the case, then the considered Be colllblister 25 follows or the previous Be Glallblister according to step S8.
  • step S10 the filling blister 25 moves according to step S10 at maximum transport speed to this next medication filling station 40, where the filling operation is carried out in method step S12.
  • the method steps S6 to S12 are repeated until it is determined in step S14 that the last intended filling station has been reached.
  • step S16 the Behellblister is removed from the Be Glallblister-removal station 61, the Behellblister 25 sealed with the blister 27 and printed (not shown) information card with patient identification information and prescription information for the patient and this information card attached to the blister. Finally, the filled and information card-filled blister 25 is ready for shipment (step S20).
  • FIG. 8 shows schematically the different states of motion of the Be colllblister.
  • Movement state (1) illustrated by a hatched rectangle with arrow, denotes a movement with maximum speed to the next drug filling station to be controlled or to a "queue" of preceding Be Shellblister
  • movement state (2) illustrated by a filled rectangle, indicates a filling a drug delivery station 40
  • motion state (3) illustrated by a hatched rectangle with no arrow
  • motion state (4) illustrated by a canted rectangle, indicates the return movement an empty workpiece carrier 20 to the Be Glallblister-Avemlagestation 60.
  • the invention allows for the time-critical process of filling the Be Glallblisters 25 from the mechanically difficult process of ejecting the medicament units from the Stsammlungblister 45 by the use of the between the strip blister 45 and the Be Schollblister 25 intermediate predosing 50, and thus the performance and reliability of the blistering process significantly increase. Furthermore, the possibility of manual filling of the pre-metering magazine allows the verbally meaningful extension of the blistering even on very rarely prescribed drugs.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Basic Packing Technique (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)

Claims (14)

  1. Installation permettant le garnissage personnalisé d'emballages à remplir (25) de médicaments en fonction de données de prescription prédéfinies, les emballages à remplir (25) comprenant des compartiments disposés selon une configuration matricielle en lignes correspondant à un certain nombre d'heures de prise pendant une journée et en colonnes correspondant à un certain nombre de jours, par exemple de jours de la semaine, pour des unités respectives d'administration de médicaments, comprenant :
    une pluralité de stations de remplissage en médicaments (40) disposées les unes derrière les autres et destinées à garnir les emballages à remplir (25) de respectivement un médicament en particulier,
    et un dispositif de transport (10) conçu pour transporter les emballages à remplir (25) chacun l'un derrière l'autre dans une direction de déplacement le long des stations de remplissage en médicaments (40),
    chaque station de remplissage en médicaments (40) comprenant un chargeur de pré-dosage (50) mobile entre deux positions, pourvu de plusieurs compartiments de pré-dosage (51) et conçu, lorsqu'il se trouve dans une première position, pour loger le médicament dans un ou plusieurs des compartiments de pré-dosage (51) et, lorsqu'il se trouve dans une seconde position, pour distribuer le médicament à partir des compartiments de pré-dosage (51) dans des compartiments (26) correspondants de l'emballage à remplir (25),
    caractérisée en ce que le médicament est amené dans chaque station de remplissage en médicaments (40) au moyen d'un emballage à bandes (45) et chaque station de remplissage en médicaments (40) comprend un ou plusieurs poussoirs d'éjection (42) permettant d'éjecter le médicament d'alvéoles (46) de l'emballage à bandes dans les compartiments de pré-dosage (51) du chargeur de pré-dosage (50),
    une zone de salle blanche (30) étant présente dans la zone de transfert des médicaments dans les emballages à remplir (25), et
    les emballages à remplir (25), une fois remplis, étant scellés par un film (27).
  2. Installation selon la revendication 1, l'emballage à bandes (45) étant mobile dans une station de remplissage en médicaments (40) dans une seule direction.
  3. Installation selon l'une quelconque des revendications 1-2, le chargeur de pré-dosage (50) comprenant un fond (55) mobile dans la direction transversale dans la seconde position dudit chargeur pour distribuer le médicament dans les compartiments (26) de l'emballage à remplir (25).
  4. Installation selon l'une quelconque des revendications 1 à 3, les compartiments de pré-dosage (51) du chargeur de pré-dosage (50) étant alignés de telle manière qu'ils sont disposés dans la seconde position respectivement au-dessus des compartiments (26) de l'emballage à remplir (25) disposés en ligne en fonction d'un certain nombre de jours (de la semaine).
  5. Installation selon l'une quelconque des revendications précédentes, chaque station de remplissage en médicaments (40) comprenant au moins un dispositif de détection (47, 48) permettant de contrôler la réception correcte du médicament dans les compartiments de pré-dosage (21) du chargeur de pré-dosage (50) et/ou la distribution correcte du médicament dans les compartiments (26) de l'emballage à remplir (25).
  6. Installation selon la revendication 5, caractérisée en ce que le chargeur de pré-dosage (50) comprend dans la zone de la position de repos d'un médicament des fentes (52) disposées latéralement dans les compartiments de pré-dosage (51) et un premier dispositif de détection (47) étant conçu pour détecter optiquement à travers les fentes (52) un médicament dans les compartiments de pré-dosage (51) pendant un déplacement du chargeur de pré-dosage (50) de la première à la seconde position et inversement.
  7. Installation selon la revendication 5 ou 6, le fond des compartiments de pré-dosage (51) du chargeur de pré-dosage (50) étant transparent ou réfléchissant la lumière et un second dispositif de détection (48) comprenant une caméra permettant de détecter des médicaments situés sur le fond des compartiments de pré-dosage (51).
  8. Installation selon l'une quelconque des revendications précédentes, le chargeur de pré-dosage (50) comprenant un revêtement intérieur remplaçable en matière plastique.
  9. Installation selon l'une quelconque des revendications précédentes, le dispositif de transport (10) étant réalisé sous la forme d'une bande magnétique pourvue d'un moteur linéaire permettant l'entraînement des emballages à remplir (25).
  10. Installation selon l'une quelconque des revendications précédentes, le dispositif de transport (10) étant conçu pour transporter des porte-pièce (20) guidés dans un rail magnétique (11) et destinés à recevoir les emballages à remplir (25).
  11. Installation selon la revendication 10, le dispositif de transport (10) étant réalisé sous la forme d'une bande fermée sur laquelle les porte-pièce (20) sont transportés dans un circuit fermé, les emballages à remplir (25), avant d'être garnis, étant posés sur les porte-pièce (20) et à nouveau retirés après la procédure de garnissage.
  12. Installation selon l'une quelconque des revendications précédentes, comprenant en outre une caméra disposée au-dessus du dispositif de transport (10) et destinée au contrôle optique du garnissage correct des emballages à remplir (25) en fonction des données de prescription.
  13. Installation selon l'une quelconque des revendications précédentes, le chargeur de pré-dosage (50) permettant l'amenée manuelle d'un médicament étant librement accessible dans ce dernier.
  14. Installation selon l'une quelconque des revendications précédentes, comprenant un dispositif permettant de mettre en place et d'adjoindre un support de document sur l'emballage à remplir (25) comprenant une information relative à une personne et/ou une information d'utilisation des médicaments emballés dans l'emballage à remplir (25).
EP13151166.9A 2013-01-14 2013-01-14 Installation destinée au garnissage pour une personne de blisters avec des médicaments selon des informations de prescription prédéfinies Not-in-force EP2754615B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP13151166.9A EP2754615B1 (fr) 2013-01-14 2013-01-14 Installation destinée au garnissage pour une personne de blisters avec des médicaments selon des informations de prescription prédéfinies
PCT/EP2014/050151 WO2014108402A1 (fr) 2013-01-14 2014-01-07 Installation permettant le remplissage personnalisé d'emballages-coques à remplir de médicaments en fonction de données de prescription prédéfinies
US14/760,593 US20150353213A1 (en) 2013-01-14 2014-01-07 Installation for individually tailored filling of blister packs with medication according to predetermined prescription data
CA2897748A CA2897748A1 (fr) 2013-01-14 2014-01-07 Installation permettant le remplissage personnalise d'emballages-coques a remplir de medicaments en fonction de donnees de prescription predefinies
CN201480004827.8A CN104918856B (zh) 2013-01-14 2014-01-07 根据预定的处方数据用药物个人定制地填充泡罩包装的设备

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13151166.9A EP2754615B1 (fr) 2013-01-14 2013-01-14 Installation destinée au garnissage pour une personne de blisters avec des médicaments selon des informations de prescription prédéfinies

Publications (2)

Publication Number Publication Date
EP2754615A1 EP2754615A1 (fr) 2014-07-16
EP2754615B1 true EP2754615B1 (fr) 2015-07-29

Family

ID=47559293

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13151166.9A Not-in-force EP2754615B1 (fr) 2013-01-14 2013-01-14 Installation destinée au garnissage pour une personne de blisters avec des médicaments selon des informations de prescription prédéfinies

Country Status (5)

Country Link
US (1) US20150353213A1 (fr)
EP (1) EP2754615B1 (fr)
CN (1) CN104918856B (fr)
CA (1) CA2897748A1 (fr)
WO (1) WO2014108402A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2993133B1 (fr) 2014-09-08 2017-03-29 Edwin Kohl Installation et procédé de changement d'emballage de différents médicaments à partir de leur blister transparent dans des blisters de remplissage
WO2016040855A1 (fr) * 2014-09-12 2016-03-17 Becton, Dickinson And Company Système de tri et de distribution de médicaments par voie orale
EP3081927B1 (fr) * 2015-04-17 2018-01-31 Becton Dickinson Rowa Germany GmbH Dispositif d'emballage de portions individuelles de médicament et son procédé de fonctionnement
CN107672872B (zh) * 2017-11-02 2023-03-21 上海佰润诺机械制造工程有限公司 物料传输装置
CN110758802A (zh) * 2019-11-11 2020-02-07 上海林康医疗信息技术有限公司 一种药品分装设备
US11779518B2 (en) 2021-08-09 2023-10-10 Express Scripts Strategic Development, Inc. Blister pack device and method
EP4273060A1 (fr) * 2022-04-08 2023-11-08 Knapp AG Procédé de fonctionnement d'un dispositif d'emballage pour re-emballer des médicaments se présentant sous forme de comprimés et procédé de fonctionnement d'un dispositif d'emballage
DE102022114115A1 (de) 2022-04-08 2023-10-12 Knapp Ag Tablettenträger zum Zwischentransport von Tabletten in einem Verblisterungsprozess, Befüllvorrichtung für einen Tablettenträger und Verfahren zum Befüllen eines Tablettenträgers
WO2023194555A1 (fr) * 2022-04-08 2023-10-12 Knapp Ag Procédé pour faire fonctionner un dispositif de suremballage destiné à suremballer des médicaments présents sous la forme de comprimés et procédé pour faire fonctionner un dispositif de suremballage

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2704177A (en) * 1950-02-17 1955-03-15 Thompson Machine Company Roll panning machine
GB716569A (en) * 1952-01-30 1954-10-06 Kellog Co Conveyor apparatus for separating articles fed thereto in seriatim
US3417542A (en) * 1965-11-26 1968-12-24 Merrill Machinery Company Desiccant capsule feeding machine
USRE27405E (en) * 1970-06-10 1972-06-27 Candy packaging machine
US3874143A (en) * 1972-07-12 1975-04-01 Lehigh Press Packaging method and apparatus
US4101284A (en) * 1977-10-25 1978-07-18 Abbott Laboratories Multiple bead dispenser for diagnostic assay
FR2427257A1 (fr) * 1978-05-29 1979-12-28 Expandet Sa Machine distributrice pour la mise en place d'objets stockes sur des grilles presentoirs
US4428709A (en) * 1980-11-28 1984-01-31 Automation International Corp. De-packaging apparatus
FR2518055A1 (fr) * 1981-12-16 1983-06-17 Freville Smum Sarl Dispositif pour detecter le manque d'ampoules ou les ampoules a pointe cassee dans une chaine de conditionnement d'ampoules
EP0104142A3 (fr) * 1982-09-16 1985-05-02 Hollymatic AG Ingenbohl Dispositif pour déposer des objets à un endroit précis
US4677808A (en) * 1984-03-15 1987-07-07 Sapal, Societe Anonyme Des Plieuses Automatiques Assembly for assorted packings with different products
DE3541672A1 (de) * 1985-11-26 1987-05-27 Uhlmann Maschf Josef Vorrichtung an verpackungsmaschinen zum geordneten zufuehren und ablegen zu verpackender kleinteile, wie tabletten, kapseln, dragees oder dergl.
US4655026A (en) * 1985-12-11 1987-04-07 Wigoda Luis T Pill dispensing machine
IT1201613B (it) * 1986-12-23 1989-02-02 Ima Spa Dispositivo per il rilevamento e della presenza di prodotti in corrispondenti sedi e di irregolarita'nel profilo di base di tali prodotti gia'collocati nelle relative sedi
US5568715A (en) * 1994-05-31 1996-10-29 Johnson & Johnson Vision Products, Inc. Automated inspection system with transport and ejector conveyor
SE505889C2 (sv) * 1996-01-19 1997-10-20 Hans Erik Persson Förpackning för tabletter eller liknande jämte utstötaranordning härför
ITBO20000402A1 (it) * 2000-07-06 2002-01-06 Marchesini Group Spa Unita' per l' alimentazione di articoli a un nastro alveolato .
US7134258B2 (en) * 2001-12-05 2006-11-14 R.A. Jones & Co. Inc. Packaging apparatus and methods
DE102004006375A1 (de) * 2004-02-09 2005-09-15 Uhlmann Pac-Systeme Gmbh & Co Kg Verfahren und Vorrichtung zum Überführen von Produkten aus einem Vorratsgefäß in die Näpfe einer Folie
DE102004020510B4 (de) 2004-04-26 2007-11-29 Edwin Kohl Anlage zur Bestückung von Verpackungseinheiten mit dem verordnungsgemäßen Wochenbedarf von Patienten entsprechenden Medikamenten
DE102004034024A1 (de) 2004-04-26 2006-02-09 Klingel, Hans, Dr.-Ing. h.c. Verpackungseinheit für den wöchentlichen Medikamentenbedarf eines Patienten
DE102004049560B4 (de) * 2004-10-12 2006-08-31 Mediseal Gmbh Verfahren und Vorrichtung zum Einlegen von Tabletten in die Höfe einer tiefgezogenen Bodenfolie
EP1800645A1 (fr) * 2005-12-21 2007-06-27 Körber AG Emballage pour produits médicaux et autres
US20100139222A1 (en) * 2007-04-17 2010-06-10 Micron Pharmaworks, Inc. Product filling system
US7971414B1 (en) * 2007-05-30 2011-07-05 Walgreen Co. Multi-dose filling machine
US7784244B2 (en) * 2007-08-13 2010-08-31 Mts Medication Technologies, Inc. High speed automated filling of solid pharmaceutical product packaging via a conveyor system
EP2062822A1 (fr) * 2007-11-24 2009-05-27 UHLMANN PAC-SYSTEME GmbH & Co. KG Procédé et dispositif de remplissage individuel de blisters
ES2336880B1 (es) * 2008-04-02 2011-02-10 Marti Garcia Sala Maquina dispensadora de envases de tipo blister.
DE102009012558A1 (de) * 2009-03-10 2010-09-23 Wipotec Wiege- Und Positioniersysteme Gmbh Kontrollvorrichtung für eine Produktionsmaschine
EP2343243B1 (fr) * 2010-01-07 2012-06-13 Uhlmann VisioTec GmbH Installation destinée au remplissage controlé de produits pharmaceutiques solides
DE102010028568A1 (de) * 2010-05-04 2011-11-10 Uhlmann Pac-Systeme Gmbh & Co Kg Vorrichtung zur Befüllung von patientenindividuellen Verpackungen
US9008831B1 (en) * 2012-09-25 2015-04-14 Rockwell Automation, Inc. Packaging system and method utilizing intelligent conveyor systems

Also Published As

Publication number Publication date
CN104918856B (zh) 2017-03-29
EP2754615A1 (fr) 2014-07-16
WO2014108402A1 (fr) 2014-07-17
US20150353213A1 (en) 2015-12-10
CA2897748A1 (fr) 2014-07-17
CN104918856A (zh) 2015-09-16

Similar Documents

Publication Publication Date Title
EP2754614B1 (fr) Installation et procédé destinés au remplissage pour une personne de blisters avec des médicaments
EP2754615B1 (fr) Installation destinée au garnissage pour une personne de blisters avec des médicaments selon des informations de prescription prédéfinies
EP1740459B1 (fr) Installation pour remplir des unites d'emballage avec des medicaments, en fonction des besoins hebdomadaires de patients definis par une prescription medicale
EP2993133B1 (fr) Installation et procédé de changement d'emballage de différents médicaments à partir de leur blister transparent dans des blisters de remplissage
EP1966066B1 (fr) Systeme de stockage automatise et procede de stockage et de distribution de medicaments
WO2005087175A1 (fr) Procede et systeme de remplissage automatique de comprimes
EP0948306A1 (fr) Procede et dispositif de distribution automatique d'objets individuels, notamment d'une pilule individuelle
WO2007141192A1 (fr) Système de remplissage personnalisé de distributeurs de médicaments
DE3818705C2 (fr)
DE60128348T2 (de) Automatische maschine zum verpacken von festen pharmazeutischen produkten
DE102010028568A1 (de) Vorrichtung zur Befüllung von patientenindividuellen Verpackungen
EP2818420B1 (fr) Procédé de remplissage sécurisé d'une boîte de transport présentant une pluralité de surfaces de réception en utilisant une station d'entrée/sortie mettant à disposition de façon séquentielle des emballages de médicament provenant d'un stock automatisé et station d'entrée/sortie correspondante
EP3081500B1 (fr) Dispositif de fabrication de blister souple
DE102008047975B4 (de) Vorrichtung zur individuellen Zusammenstellung von Tabletten
DE3842273A1 (de) Vorrichtung zum fuellen von vertiefungen in blisterpackungen
WO2019227110A1 (fr) Contenant à médicaments
EP0416627A1 (fr) Procédé et dispositif pour stocker et reprendre automatiquement des sortes de marchandises de détail de rayonnages dans de grands entrepôts
DE102007004152A1 (de) Vorrichtung und Verfahren zum Befüllen von Patientenblistern
DE102022114943A1 (de) Umverpackungsvorrichtung zum Umverpacken von in Tablettenform vorliegenden Medikamenten und Verfahren zum Betreiben einer Umverpackungsvorrichtung
DE2734664C2 (fr)
DE102009017869B3 (de) Verfahren zum individuellen Zusammenstellen von Tabletten sowie Vorrichtung zur Durchführung des Verfahrens
DE102017129560B4 (de) Vorrichtung und System für eine Verblisterung von Arzneimitteln und Verfahren zum Betreiben dafür
DE102018125003B4 (de) Anordnung aus einem Spendersystem für Medikamente und einem Vorratssystem zur Bevorratung und der Medikamenten
EP3720775A1 (fr) Dispositif et système de mise sous blister de médicaments et procédé de fonctionnement afférent
DE102017201601A1 (de) Vorrichtung zur Ausgabe von Tabletten, sowie eine Aufnahmeeinrichtung für eine Blisterverpackung und ein Herstellungsverfahren für eine solche Aufnahmeeinrichtung

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20130114

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

R17P Request for examination filed (corrected)

Effective date: 20150116

RBV Designated contracting states (corrected)

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

RIC1 Information provided on ipc code assigned before grant

Ipc: B65B 5/10 20060101AFI20150303BHEP

Ipc: B65B 69/00 20060101ALI20150303BHEP

Ipc: G07F 11/00 20060101ALI20150303BHEP

Ipc: B65B 9/04 20060101ALI20150303BHEP

INTG Intention to grant announced

Effective date: 20150323

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 739051

Country of ref document: AT

Kind code of ref document: T

Effective date: 20150815

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

Free format text: LANGUAGE OF EP DOCUMENT: GERMAN

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 502013000929

Country of ref document: DE

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: RENTSCH PARTNER AG, CH

REG Reference to a national code

Ref country code: NO

Ref legal event code: T2

Effective date: 20150729

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

REG Reference to a national code

Ref country code: NL

Ref legal event code: MP

Effective date: 20150729

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 4

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151030

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151130

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151129

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: IT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 502013000929

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160131

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20160502

REG Reference to a national code

Ref country code: NO

Ref legal event code: MMEP

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: LU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20160114

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160131

Ref country code: NO

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160131

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160131

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 5

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20160114

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20170124

Year of fee payment: 5

Ref country code: DE

Payment date: 20170131

Year of fee payment: 5

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20170125

Year of fee payment: 5

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20130114

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 502013000929

Country of ref document: DE

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20180114

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180801

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180131

REG Reference to a national code

Ref country code: FR

Ref legal event code: ST

Effective date: 20180928

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180114

REG Reference to a national code

Ref country code: AT

Ref legal event code: MM01

Ref document number: 739051

Country of ref document: AT

Kind code of ref document: T

Effective date: 20180114

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20180114