EP2718198A1 - Stoppvorrichtung und behälter damit - Google Patents

Stoppvorrichtung und behälter damit

Info

Publication number
EP2718198A1
EP2718198A1 EP12729072.4A EP12729072A EP2718198A1 EP 2718198 A1 EP2718198 A1 EP 2718198A1 EP 12729072 A EP12729072 A EP 12729072A EP 2718198 A1 EP2718198 A1 EP 2718198A1
Authority
EP
European Patent Office
Prior art keywords
ring
cover
neck
cap
plug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP12729072.4A
Other languages
English (en)
French (fr)
Other versions
EP2718198B1 (de
Inventor
Antoine Aneas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocorp Production SA
Original Assignee
Biocorp Recherche et Developpement
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocorp Recherche et Developpement filed Critical Biocorp Recherche et Developpement
Priority to PL12729072T priority Critical patent/PL2718198T3/pl
Publication of EP2718198A1 publication Critical patent/EP2718198A1/de
Application granted granted Critical
Publication of EP2718198B1 publication Critical patent/EP2718198B1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/18Arrangements of closures with protective outer cap-like covers or of two or more co-operating closures
    • B65D51/20Caps, lids, or covers co-operating with an inner closure arranged to be opened by piercing, cutting, or tearing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/18Arrangements for indicating condition of container contents, e.g. sterile condition
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/002Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/18Arrangements of closures with protective outer cap-like covers or of two or more co-operating closures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/24Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
    • B65D51/241Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes provided with freeze-drying means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1406Septums, pierceable membranes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00Details relating to container closures
    • B65D2251/0003Two or more closures
    • B65D2251/0006Upper closure
    • B65D2251/0009Upper closure of the 17-type
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00Details relating to container closures
    • B65D2251/0003Two or more closures
    • B65D2251/0068Lower closure
    • B65D2251/009Lower closure of the 51-type

Definitions

  • the invention relates to a closure device for a container, this device comprising a plug designed to close the neck of the container, and a cap.
  • the invention also relates to a container, for example a medicine bottle, equipped with such a closure device.
  • DE-A-195 32 980 teaches to provide a continuous line of rupture between a cover and a ring belonging to the cap of a closure device. This continuous line can be difficult to break for an inexperienced user or an elderly person.
  • the invention intends to remedy more particularly by proposing a new closure device which is particularly simple and intuitive to use. implement and which allows, among other things, an easy and quick removal of the lid for easy access to the contents of a container.
  • the invention relates to a closure device for a container provided with a neck, this device comprising a cap and a plastic cap capable of covering both the neck and the plug in place in the neck, the cap comprising a ring, adapted to surround the cap and collar in mounted configuration and provided with locking means on the neck, and a cover.
  • the ring and the cover are made in one single piece connected by at least one part which is breakable by means of a force parallel to a central axis of the ring and directed towards the stopper, while the cover is equipped with a support element against the plug.
  • This closure device is characterized in that the breakable portion is formed by bridges which extend radially between an outer radial edge of the cover and an inner radial edge of the ring, in that a circular arc light is defined between two adjacent bridges, along the outer radial edge of the cover and the inner radial edge of the ring and in that this light has a radial width less than 0.3 mm and an axial height greater than 0.15 mm.
  • the removal of the cap is particularly easy since it is sufficient to exert on it a force directed towards the cap, that is to say in practice towards the bottom of a bottle equipped with the device. capping, to obtain the rupture of the bridges of the breakable zone.
  • the lid rests against the cap with its support member, the lid undergoes an elastic deformation force from the cap, which allows to easily eject the lid relative to the ring of the once the broken part is broken, thus freeing access to the cap.
  • the invention proceeds from an unusual approach in the field of drug conditioning where users have the habit of covers that can be removed by a lateral force (called “flip off”), by a tensile force (called “tear”).
  • Each bridge has a preferred break zone that is closer to the attachment area of the bridge on the ring that the attachment area of the bridge on the lid.
  • the locking means comprise teeth each defining a locking surface perpendicular to a central axis and the ring and intended to bear against a surface of a collar external to the neck.
  • An annular portion of the ring which covers an upper surface of the plug in mounted configuration of the closure device on the container, is pierced with pin opening openings to unmold the locking surfaces of the teeth.
  • the cross section of a passage opening of a demolding pin has an area greater than the area of the blocking surface located opposite this opening, in a direction parallel to the central axis of the ring.
  • Each tooth defines a sliding surface against the flange, this surface being in cone-truncated portion and diverging opposite the cover relative to the central axis of the ring.
  • the bridges have an axial thickness, measured parallel to a central axis of the lid, between 0.1 mm and 0.3 mm, preferably between 0.2 mm and 0.25 mm.
  • the cover extends along the central axis of the ring, projecting from an edge of the ring opposite the locking means.
  • the cover extends, with respect to the aforementioned edge of the ring, on an axial height greater than or equal to twice the axial thickness of the bridges, preferably greater than or equal to three times this thickness, more preferably equal to at four times that thickness.
  • the support element of the lid on the cap is constituted by a pin which extends along the central axis of the lid, in the direction of the plug, until contact therewith.
  • the support member of the lid exerts on the cap a force of elastic deformation of a central portion of the plug aligned on the neck of the container.
  • the cap exerts on the support member an elastic force of ejection of the plug, this elastic force resulting from the elastic deformation force of the central portion of the cap previously exerted by the element d 'support.
  • the cover is connected by the breakable portion to an annular portion of the ring which is perpendicular to a skirt of this ring, intended to surround the neck of the container and equipped with locking means, while the annular portion is provided with at least one opening and each opening is bordered, on the plug side, by a rib for superficially penetrating the plug, radially on the inside of the opening .
  • the invention also relates to a container, in particular a medicine bottle, which is equipped with a closure device as mentioned above.
  • FIG. 1 is a perspective view of a medication vial equipped with a closure device according to the invention
  • FIG. 2 is a perspective view, partially broken away, of the upper part of the bottle of FIG. 1;
  • FIG. 3 is a partial section along plane III in FIG. 2 and represents intrusion temptations on the bottle
  • FIG. 4 is a partial section along plane IV in FIG. 2,
  • FIG. 5 is an exploded axial section, in the same plane as FIG. 3 of the closure device alone,
  • FIG. 6 is a perspective view of the cap of the device of FIG. 5, at a first angle
  • FIG. 7 is a view of the cap of FIG. 6 according to another angle
  • FIG. 8 is a perspective view of the lid, after its separation from the ring,
  • FIG. 9 is a view from below of the bottle of FIG. 1, to the scale of FIG. 3, there is shown in III-III and IV-IV the sectional planes of FIGS. 3 and 4,
  • FIGS. 10 to 13 represent several successive stages of use of the bottle of the preceding figures.
  • Figure 14 is a representation similar to Figure 12 and corresponds to another way of using the bottle.
  • the bottle 1 shown in the figures is made of glass and comprises a neck 1 1 which is defined by a neck 12 having an outer collar 13.
  • X1 is the axis of symmetry of the bottle 1 which is also a central axis of the neck 12 and flange 13.
  • Note 14 the bottom of the bottle 1 which is opposite the neck 1 1.
  • 132 and 134 are respectively noted the surfaces of the flange 13 which are oriented opposite the bottom 14 and towards this background. In other words, the surfaces 132 and 134 respectively constitute the lower and upper surfaces of the flange 13 when the flask 1 rests at its bottom 14 on a plane and horizontal surface S, as represented in FIGS. 10 to 13.
  • a pipette 200 is introduced into it, through its neck 1 1, as shown in FIG. 10.
  • the pipette 200 is removed and a closure device 20 is placed on the neck 12.
  • the device 20 comprises an elastomeric stopper 21 of shape adapted to be partially introduced into the neck 1 1, while resting on the face 132 of the 13.
  • the stopper 21 is in one piece and comprises a disk-shaped plate 21 1 intended to rest on the surface 132 as well as a hollow rod 212 intended to penetrate into the neck 11.
  • the cap 21 isolates the contents of the bottle 1 from the outside.
  • X21 is a central axis of symmetry of the plug 21. In mounted configuration of the cap 21 on the bottle 1, the axes X1 and X21 are merged.
  • the device 20 also comprises a cap 24 intended to cover and isolate the cap 21 and the neck 12 from the outside in the closed configuration of the closure device.
  • the cap 24 comprises a ring 25 and a cover 26 which are molded together and form a single piece as a cap 24. In other words, a continuity of material exists between the elements 25 and 26, within the cap 24 .
  • the ring 25 is provided with five locking teeth 253 under the surface 134 of the collar 13.
  • An outer peripheral skirt of the ring 25 and X25 is noted as a central axis of this ring.
  • This skirt is equipped, on its inner radial surface 251 A, teeth 253 with triangular section.
  • Each tooth 253 defines a blocking surface 253A perpendicular to the axis X25 and intended to bear against the surface 134 when the cap 24 is in place around the neck 12 of the bottle 1.
  • Each tooth 253 also defines a sliding surface 253B which is provided for sliding on a junction zone between the surface 132 and the outer radial surface of the flange 13 during the placement of the cap 24 on the neck 12.
  • the skirt 251 expands radially, elastically, during the passage of the teeth 253 at the collar 13, along the axis X1, before the teeth 253 come to lock under the flange 13, the surfaces 253A then coming opposite the surface 134 of the flange 13.
  • the teeth 253 constitute the locking means of the ring 25 on the neck 12 of the flask 1.
  • 253B surfaces are in portion of truncated cone and diverging downwards, which ensures the progressiveness of the elastic radial expansion of the skirt 251 to the passage of the flange 13.
  • the 254 is the annular portion of the ring 25 which partially covers the upper surface 213 of the plug 21 in the mounted configuration of the device 20 on the bottle 1, that is to say the surface of the plate 21 1 opposite the rod 212.
  • the portion 254 is perpendicular to the skirt 251 and pierced with five openings 255 for the passage of a molding drawer surfaces 253A.
  • the surface 213 is accessible through these openings 255.
  • Each opening 255 has, in cross section relative to the axis X25, a sufficient area to allow the passage of demolding pins 253A blocking surfaces of the teeth 253. This area is greater than the area of the surface 253A arranged next to the opening 255, in a direction parallel to the axis X25.
  • the lid 26 is circular and centered on an axis X26 which is coincident with the axis X25 when the elements 25 and 26 of the cap 24 are integral. 261 the outer radial edge of the cover 26 and D26 its maximum outside diameter.
  • Part 254 is provided with a circular central opening 256 centered on the axis X25 and whose diameter is noted d256.
  • the diameter D26 is strictly less than the diameter d256 and the edge 261 is disposed along the axes X25 and X26 together, at the edge 257 of the portion 254 which defines the orifice 256, radially inside this edge.
  • the elements 25 and 26 are connected by four bridges 27 which extend, radially with respect to the axes X25 and X26, between the edges 261 and 257 and which are in the form of trapezium with their smaller base 271 on the edge side 257.
  • the cover 26 also comprises a pin 262 centered on the axis X26 and turned towards the edge 251 B of the skirt 251 situated in the vicinity of the teeth 253. In other words, the pin 262 is turned towards the plug 21 in mounted configuration of the device 20.
  • the axial thickness of the bridges 27, that is to say their thickness measured parallel to the axis X26.
  • This thickness e27 is chosen so that the bridges 27 can be broken under the effect of a force E1 parallel to the axes X25 and X26 and directed towards the plug 21, that is to say towards the bottom 14 of a bottle 1 in which is mounted the device 20.
  • the value of the thickness e27 is chosen between 0.1 mm and 0.3 mm, preferably between 0.2 mm and 0.25 mm to allow effective immobilization of the cover 26 relative to the ring 25 before breaking of the saddles and an easy break under the effect of an axial force, when necessary.
  • FIGS. 2 to 4 show that, in the mounted configuration of the device 20 on the bottle 1, the pin 262 of the lid 26 exerts a deformation force on the central portion 214 of the plate 21 1 situated opposite the hollow interior volume of the stem 212.
  • This deformation is elastic, so that when the bridges 27 are broken, the elastic force E2 exerted by the plug 21 on the pin 262 of the lid 26 ejects it from the orifice 256.
  • the user does not have to pull the cover 26 to separate the parts 21 and 24 of the device 20 which remain in place on the bottle 1 since the elastic force E2 performs this function.
  • the lid 26 protrudes beyond the surface 258 with respect to the ring 25 over a height H measured parallel to the axis X26 which is at least two times greater than the thickness e27.
  • This surface is flat on an annular portion, with a central recess corresponding to the base of the pin 262.
  • the force E1 is exerted on the lid 26 to bring to the same axial level, along the axes X25 and X26 so merged, the annular portion of the surface 268 and the surface 258.
  • This induces a break suddenly of the bridges 27 insofar as this corresponds to an axial displacement of the cover 26 on the height H which is at least twice the thickness e27.
  • the bridges 27 can not withstand a shear force inducing a displacement twice their thickness.
  • a tapered tool such as a needle 300A from a hypodermic syringe into one of the lumens 28, in a position allowing access to the contents of the bottle 1 without removing the lid 26.
  • the width 28 is chosen less than 0.3 mm, preferably equal to 0.2 mm, while the height H28 is chosen greater than 0.15 mm, preferably equal to 0 , 2 mm.
  • a needle 300A can be introduced only in a direction generally parallel to the axes X25 and X26, a position in which it would abut against the surface 132 if it were driven deeply into the plate 21 1.
  • each opening 255 is bordered, radially on the inside and on the side opposite the surface 258, by a rib 259 which penetrates superficially into the surface 213.
  • a rib 259 which penetrates superficially into the surface 213.
  • the axial height H251 of the skirt 251, in its portion which projects beyond the surface 134, is chosen, as a function of the dimensions of the neck 12, so that the annular space E which remains between the edge 251 B and the body of the bottle 1 does not allow the introduction of a needle 300C that in a position where it abuts against the neck 12, without the possibility of acting on the teeth 253. This avoids fraudulent manipulation allows an unscrupulous user to remove the ring 25 of the collar 12.
  • the device 20 guarantees the integrity of the contents of the bottle 1.
  • the operation of the device 20 is as follows:
  • the lid 26 is separated from the bottle 1 by virtue of the elastic force E2 exerted on the lid by the stopper 21.
  • the material used to mold the cap 24 may be a polyoxymethylene or a polypropylene and it is chosen to induce a clean break at the level of the small bases 271 of the bridges 27.
  • the preferred breaking zones of the bridges 27 may be formed not in contact with the edge 257 but at a short radial distance therefrom.
  • the radial distance between these preferred breaking zones and the edge 257 is less than the radial distance between these preferred breaking zones and the attachment zones of the bridges 27 on the edge 261. This relationship is also verified in the case shown in the figures since, in this case, the axial distance between the small bases 271 and the edge 257 is zero, therefore less than the radial length of the bridges 27.
  • the number of jumpers used in the invention is not necessarily equal to four. It is chosen according to the desired resistance to the driving force of the cover 26 against the elastic force E2.
  • the bridges 27 may be replaced by a continuous breakable zone, in the form of a membrane.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
EP12729072.4A 2011-06-08 2012-06-07 Stoppvorrichtung und behälter damit Active EP2718198B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL12729072T PL2718198T3 (pl) 2011-06-08 2012-06-07 Urządzenie do zatykania oraz pojemnik wyposażony w takie urządzenie

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1155015A FR2976265B1 (fr) 2011-06-08 2011-06-08 Dispositif de bouchage et recipient equipe d'un tel dispositif
PCT/EP2012/060788 WO2012168353A1 (fr) 2011-06-08 2012-06-07 Dispositif de bouchage et récipient équipé d'un tel dispositif

Publications (2)

Publication Number Publication Date
EP2718198A1 true EP2718198A1 (de) 2014-04-16
EP2718198B1 EP2718198B1 (de) 2015-07-29

Family

ID=46331272

Family Applications (1)

Application Number Title Priority Date Filing Date
EP12729072.4A Active EP2718198B1 (de) 2011-06-08 2012-06-07 Stoppvorrichtung und behälter damit

Country Status (13)

Country Link
US (1) US9505533B2 (de)
EP (1) EP2718198B1 (de)
JP (2) JP6309890B2 (de)
CN (1) CN103687792B (de)
AU (1) AU2012266372B2 (de)
BR (1) BR112013031533A2 (de)
CA (1) CA2838127C (de)
ES (1) ES2546164T3 (de)
FR (1) FR2976265B1 (de)
PL (1) PL2718198T3 (de)
PT (1) PT2718198E (de)
RU (1) RU2605173C2 (de)
WO (1) WO2012168353A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2967655B1 (fr) * 2010-11-24 2014-03-14 Biocorp Rech Et Dev Dispositif de bouchage d'un recipient, recipient equipe d'un tel dispositif et procede de fermeture d'un lot de tels recipients
EP3042862B1 (de) * 2013-09-02 2018-10-17 Taisei Kako Co., Ltd. Kappe für phiolen
CA2891612C (en) 2014-11-13 2021-06-08 Cornerstone Cm, Inc. Evacuated bottle system
US9517922B2 (en) 2014-11-13 2016-12-13 Cornerstone Cm, Inc. Evacuated bottle system
US9505599B2 (en) * 2014-11-13 2016-11-29 Cornerstone Cm, Inc. Evacuated bottle system
ES2969939T3 (es) 2015-07-12 2024-05-23 Patients Pending Ltd Tapa para sistema de suministro de líquido con detección de posición de émbolo integrada y método correspondiente
US10421585B2 (en) 2017-03-31 2019-09-24 Core Nutrition, Llc Overcap for a bottle having an inner skirt and outer skirt
US20220241149A1 (en) * 2019-07-02 2022-08-04 Taisei Kako Co., Ltd. Cap and capped vial
FR3098505B1 (fr) * 2019-07-09 2021-06-04 A Raymond Et Cie coiffe de verrouillage sécable pour récipient à col
FR3098504B1 (fr) * 2019-07-09 2021-06-04 A Raymond Et Cie coiffe de verrouillage pour récipient à col
WO2021099829A2 (en) * 2019-11-22 2021-05-27 Decoene Tine Medicine vial system
EP4098572A1 (de) * 2021-06-02 2022-12-07 SCHOTT Schweiz AG Mit einer presskappe verschlossener behälter
BE1030479B1 (fr) * 2022-04-26 2023-11-27 Laser Eng Applications Procédé et dispositif de marquage d’un container contenant une substance médicinale
WO2024086108A1 (en) * 2022-10-18 2024-04-25 Colder Products Company Vials and methods for filling vials

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2054032A (en) * 1934-07-17 1936-09-08 Colt S Mfg Co Container closure means
US2560793A (en) * 1949-12-09 1951-07-17 Inter Seal Corp Tamperproof closure for receptacles
US3087638A (en) * 1961-12-15 1963-04-30 Abbott Lab Closure assembly
US4089432A (en) * 1977-05-06 1978-05-16 The Upjohn Company Vial and closure
AT379069B (de) * 1984-01-11 1985-11-11 Greiner & Soehne C A Blutprobenroehrchen
DE3902672A1 (de) * 1988-06-28 1990-02-08 Wez Kunststoff Verschlussanordnung fuer pharmazeutische flaschen
DE4029832A1 (de) * 1990-09-20 1992-03-26 Duschek Dieter Verschlussanordnung fuer pharmazeutische flaschen
US5314084A (en) 1992-08-21 1994-05-24 The West Company, Incorporated Two piece all plastic seal
US5464111A (en) * 1993-03-03 1995-11-07 Sterling Winthrop Closure for medication container
JPH06312758A (ja) * 1993-04-23 1994-11-08 Aputodeito:Kk 容器の蓋構造
DE19532980A1 (de) * 1995-09-07 1997-03-13 Sanner Friedr Gmbh Co Kg Garantie-Injektionsflaschenverschluß
BR9913302A (pt) 1998-09-04 2002-09-24 Gaplast Gmbh Recipiente
CN100420609C (zh) 2003-04-28 2008-09-24 因斯蒂尔医学技术有限公司 用于填充和分配物质的具有阀组件的容器以及填充装置和方法
WO2004096113A2 (en) 2003-04-28 2004-11-11 Medical Instill Technologies, Inc. Container with valve assembly for filling and dispensing substances, and apparatus and method for filling
CN2702935Y (zh) 2003-12-20 2005-06-01 广西百年乐倩倩保健品有限责任公司 可装小容量物品的防伪防漏瓶盖
JP5132575B2 (ja) 2005-11-30 2013-01-30 ビヨコール ルシェルシュ エ ディヴェロプマン 容器用閉止装置およびそのような装置に嵌合する容器
FR2893922B1 (fr) 2005-11-30 2010-05-14 Biocorp Rech Et Dev Dispositif de bouchage pour un recipient et recipient equipe d'un tel dispositif
JP2007176557A (ja) * 2005-12-28 2007-07-12 Nipro Corp キャップ
JP5116279B2 (ja) * 2006-02-14 2013-01-09 紀伊産業株式会社 樹脂製キャップおよびそれを用いた樹脂製キャップ付容器
FR2912384B1 (fr) 2007-02-09 2009-04-10 Biocorp Rech Et Dev Sa Dispositif de bouchage pour un recipient, recipient equipe d'un tel dispositif et procede de fermeture d'un lot de tel recipient
FR2927316B1 (fr) 2008-02-11 2010-05-14 Biocorp Rech Et Dev Dispositif de bouchage a chapeau d'appui et recipient equipe d'un tel dispositif

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2012168353A1 *

Also Published As

Publication number Publication date
ES2546164T3 (es) 2015-09-21
JP2018076125A (ja) 2018-05-17
PT2718198E (pt) 2015-10-02
EP2718198B1 (de) 2015-07-29
US9505533B2 (en) 2016-11-29
WO2012168353A1 (fr) 2012-12-13
PL2718198T3 (pl) 2016-01-29
US20140209603A1 (en) 2014-07-31
AU2012266372A1 (en) 2014-01-16
CA2838127A1 (fr) 2012-12-13
CN103687792A (zh) 2014-03-26
CA2838127C (fr) 2019-01-08
BR112013031533A2 (pt) 2016-12-13
FR2976265B1 (fr) 2014-08-29
JP6309890B2 (ja) 2018-04-11
AU2012266372B2 (en) 2017-02-02
JP2014518822A (ja) 2014-08-07
RU2013157372A (ru) 2015-07-20
RU2605173C2 (ru) 2016-12-20
CN103687792B (zh) 2015-11-25
FR2976265A1 (fr) 2012-12-14

Similar Documents

Publication Publication Date Title
EP2718198B1 (de) Stoppvorrichtung und behälter damit
EP2643231B1 (de) Stöpselvorrichtung für einen behälter und mit einer solchen vorrichtung ausgestatteter behälter
EP0850178B1 (de) Vorrichtung mit originalitätssicherung zum anschluss an einen geschlossenen behälter
EP2718197B1 (de) Stoppvorrichtung und behälter damit
EP2864216B1 (de) Ausgabe- und mischvorrichtung
CA2856894C (fr) Dispositif de verrouillage de bouchon
CH662327A5 (fr) Recipient de conditionnement et de distribution d'un produit liquide et d'au moins un produit additionnel separes pendant le stockage.
CA2631385A1 (fr) Dispositif de bouchage pour un recipient et recipient equipe d'un tel dispositif
FR2893922A1 (fr) Dispositif de bouchage pour un recipient et recipient equipe d'un tel dispositif
EP2170719B1 (de) Kindersichere verschlussvorrichtung mit schraube und bund zur kenntlichmachung eines ersten öffnens
FR2908396A1 (fr) Dispositif de bouchage, recipient equipe d'un tel dispositif et procede de fabrication d'un tel dispositif
EP2822870B1 (de) Abdichtungsvorrichtung sowie behälter mit einer solchen vorrichtung
FR2598137A1 (fr) Dispositif de bouchon a visser inviolable et son procede d'assemblage.
WO1999010245A1 (fr) Flacon melangeur mettant en contact deux composants isoles avant leur prelevement et leur injection a l'aide d'une seringue
FR2938513A1 (fr) Ampoule secable a deux compartiments
FR3033319A1 (fr) Recipient destine a recevoir une dose determinee d'au moins deux produits de meme nature ou de nature differente
FR2996534A1 (fr) Capsule pour flacon
FR3087336A1 (fr) Dispositif de connexion temporaire de deux recipients
EP0082778B1 (de) Kanister und Behältereinheit bestehend aus einem Kanister und einem Flakon
FR3077564A1 (fr) Dispositif permettant de delivrer une dose controlee de produit dans un recipient

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20131227

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAX Request for extension of the european patent (deleted)
RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: BIOCORP RECHERCHE ET DEVELOPPEMENT

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

INTG Intention to grant announced

Effective date: 20150224

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: BIOCORP PRODUCTION

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 739069

Country of ref document: AT

Kind code of ref document: T

Effective date: 20150815

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

Free format text: LANGUAGE OF EP DOCUMENT: FRENCH

111L Licence recorded

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

Free format text: EXCLUSIVE LICENSE

Name of requester: NUOVA OMPI S.R.L., IT

Effective date: 20150727

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602012009167

Country of ref document: DE

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2546164

Country of ref document: ES

Kind code of ref document: T3

Effective date: 20150921

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: ARNOLD AND SIEDSMA AG, CH

REG Reference to a national code

Ref country code: PT

Ref legal event code: SC4A

Free format text: AVAILABILITY OF NATIONAL TRANSLATION

Effective date: 20150819

REG Reference to a national code

Ref country code: SE

Ref legal event code: TRGR

REG Reference to a national code

Ref country code: NL

Ref legal event code: FP

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 739069

Country of ref document: AT

Kind code of ref document: T

Effective date: 20150729

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG4D

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151030

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151029

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151129

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 5

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602012009167

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20160502

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 6

REG Reference to a national code

Ref country code: CH

Ref legal event code: PLIA

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 7

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO

Effective date: 20120607

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: MT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150729

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: NL

Payment date: 20190515

Year of fee payment: 8

Ref country code: LU

Payment date: 20190516

Year of fee payment: 8

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20190621

Year of fee payment: 8

Ref country code: PL

Payment date: 20190521

Year of fee payment: 8

Ref country code: PT

Payment date: 20190524

Year of fee payment: 8

Ref country code: IE

Payment date: 20190523

Year of fee payment: 8

Ref country code: MC

Payment date: 20190520

Year of fee payment: 8

Ref country code: DE

Payment date: 20190611

Year of fee payment: 8

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: SE

Payment date: 20190618

Year of fee payment: 8

Ref country code: BE

Payment date: 20190624

Year of fee payment: 8

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: CH

Payment date: 20190620

Year of fee payment: 8

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: ES

Payment date: 20190701

Year of fee payment: 8

Ref country code: GB

Payment date: 20190620

Year of fee payment: 8

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 602012009167

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20201207

Ref country code: MC

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200630

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

REG Reference to a national code

Ref country code: NL

Ref legal event code: MM

Effective date: 20200701

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20200607

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200607

REG Reference to a national code

Ref country code: BE

Ref legal event code: MM

Effective date: 20200630

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200701

Ref country code: PT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20210111

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200607

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200607

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200630

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200630

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200608

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20210101

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200630

REG Reference to a national code

Ref country code: SE

Ref legal event code: EUG

REG Reference to a national code

Ref country code: ES

Ref legal event code: FD2A

Effective date: 20211026

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200607

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200608

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: PL

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20200607

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20230509

Year of fee payment: 12