EP2718198A1 - Stopping device and container comprising such a device - Google Patents

Stopping device and container comprising such a device

Info

Publication number
EP2718198A1
EP2718198A1 EP12729072.4A EP12729072A EP2718198A1 EP 2718198 A1 EP2718198 A1 EP 2718198A1 EP 12729072 A EP12729072 A EP 12729072A EP 2718198 A1 EP2718198 A1 EP 2718198A1
Authority
EP
European Patent Office
Prior art keywords
ring
cover
neck
cap
plug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP12729072.4A
Other languages
German (de)
French (fr)
Other versions
EP2718198B1 (en
Inventor
Antoine Aneas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocorp Production SA
Original Assignee
Biocorp Recherche et Developpement
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocorp Recherche et Developpement filed Critical Biocorp Recherche et Developpement
Priority to PL12729072T priority Critical patent/PL2718198T3/en
Publication of EP2718198A1 publication Critical patent/EP2718198A1/en
Application granted granted Critical
Publication of EP2718198B1 publication Critical patent/EP2718198B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/18—Arrangements of closures with protective outer cap-like covers or of two or more co-operating closures
    • B65D51/20—Caps, lids, or covers co-operating with an inner closure arranged to be opened by piercing, cutting, or tearing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/18—Arrangements for indicating condition of container contents, e.g. sterile condition
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/18—Arrangements of closures with protective outer cap-like covers or of two or more co-operating closures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/24—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
    • B65D51/241—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes provided with freeze-drying means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1406—Septums, pierceable membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00—Details relating to container closures
    • B65D2251/0003—Two or more closures
    • B65D2251/0006—Upper closure
    • B65D2251/0009—Upper closure of the 17-type
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2251/00—Details relating to container closures
    • B65D2251/0003—Two or more closures
    • B65D2251/0068—Lower closure
    • B65D2251/009—Lower closure of the 51-type

Definitions

  • the invention relates to a closure device for a container, this device comprising a plug designed to close the neck of the container, and a cap.
  • the invention also relates to a container, for example a medicine bottle, equipped with such a closure device.
  • DE-A-195 32 980 teaches to provide a continuous line of rupture between a cover and a ring belonging to the cap of a closure device. This continuous line can be difficult to break for an inexperienced user or an elderly person.
  • the invention intends to remedy more particularly by proposing a new closure device which is particularly simple and intuitive to use. implement and which allows, among other things, an easy and quick removal of the lid for easy access to the contents of a container.
  • the invention relates to a closure device for a container provided with a neck, this device comprising a cap and a plastic cap capable of covering both the neck and the plug in place in the neck, the cap comprising a ring, adapted to surround the cap and collar in mounted configuration and provided with locking means on the neck, and a cover.
  • the ring and the cover are made in one single piece connected by at least one part which is breakable by means of a force parallel to a central axis of the ring and directed towards the stopper, while the cover is equipped with a support element against the plug.
  • This closure device is characterized in that the breakable portion is formed by bridges which extend radially between an outer radial edge of the cover and an inner radial edge of the ring, in that a circular arc light is defined between two adjacent bridges, along the outer radial edge of the cover and the inner radial edge of the ring and in that this light has a radial width less than 0.3 mm and an axial height greater than 0.15 mm.
  • the removal of the cap is particularly easy since it is sufficient to exert on it a force directed towards the cap, that is to say in practice towards the bottom of a bottle equipped with the device. capping, to obtain the rupture of the bridges of the breakable zone.
  • the lid rests against the cap with its support member, the lid undergoes an elastic deformation force from the cap, which allows to easily eject the lid relative to the ring of the once the broken part is broken, thus freeing access to the cap.
  • the invention proceeds from an unusual approach in the field of drug conditioning where users have the habit of covers that can be removed by a lateral force (called “flip off”), by a tensile force (called “tear”).
  • Each bridge has a preferred break zone that is closer to the attachment area of the bridge on the ring that the attachment area of the bridge on the lid.
  • the locking means comprise teeth each defining a locking surface perpendicular to a central axis and the ring and intended to bear against a surface of a collar external to the neck.
  • An annular portion of the ring which covers an upper surface of the plug in mounted configuration of the closure device on the container, is pierced with pin opening openings to unmold the locking surfaces of the teeth.
  • the cross section of a passage opening of a demolding pin has an area greater than the area of the blocking surface located opposite this opening, in a direction parallel to the central axis of the ring.
  • Each tooth defines a sliding surface against the flange, this surface being in cone-truncated portion and diverging opposite the cover relative to the central axis of the ring.
  • the bridges have an axial thickness, measured parallel to a central axis of the lid, between 0.1 mm and 0.3 mm, preferably between 0.2 mm and 0.25 mm.
  • the cover extends along the central axis of the ring, projecting from an edge of the ring opposite the locking means.
  • the cover extends, with respect to the aforementioned edge of the ring, on an axial height greater than or equal to twice the axial thickness of the bridges, preferably greater than or equal to three times this thickness, more preferably equal to at four times that thickness.
  • the support element of the lid on the cap is constituted by a pin which extends along the central axis of the lid, in the direction of the plug, until contact therewith.
  • the support member of the lid exerts on the cap a force of elastic deformation of a central portion of the plug aligned on the neck of the container.
  • the cap exerts on the support member an elastic force of ejection of the plug, this elastic force resulting from the elastic deformation force of the central portion of the cap previously exerted by the element d 'support.
  • the cover is connected by the breakable portion to an annular portion of the ring which is perpendicular to a skirt of this ring, intended to surround the neck of the container and equipped with locking means, while the annular portion is provided with at least one opening and each opening is bordered, on the plug side, by a rib for superficially penetrating the plug, radially on the inside of the opening .
  • the invention also relates to a container, in particular a medicine bottle, which is equipped with a closure device as mentioned above.
  • FIG. 1 is a perspective view of a medication vial equipped with a closure device according to the invention
  • FIG. 2 is a perspective view, partially broken away, of the upper part of the bottle of FIG. 1;
  • FIG. 3 is a partial section along plane III in FIG. 2 and represents intrusion temptations on the bottle
  • FIG. 4 is a partial section along plane IV in FIG. 2,
  • FIG. 5 is an exploded axial section, in the same plane as FIG. 3 of the closure device alone,
  • FIG. 6 is a perspective view of the cap of the device of FIG. 5, at a first angle
  • FIG. 7 is a view of the cap of FIG. 6 according to another angle
  • FIG. 8 is a perspective view of the lid, after its separation from the ring,
  • FIG. 9 is a view from below of the bottle of FIG. 1, to the scale of FIG. 3, there is shown in III-III and IV-IV the sectional planes of FIGS. 3 and 4,
  • FIGS. 10 to 13 represent several successive stages of use of the bottle of the preceding figures.
  • Figure 14 is a representation similar to Figure 12 and corresponds to another way of using the bottle.
  • the bottle 1 shown in the figures is made of glass and comprises a neck 1 1 which is defined by a neck 12 having an outer collar 13.
  • X1 is the axis of symmetry of the bottle 1 which is also a central axis of the neck 12 and flange 13.
  • Note 14 the bottom of the bottle 1 which is opposite the neck 1 1.
  • 132 and 134 are respectively noted the surfaces of the flange 13 which are oriented opposite the bottom 14 and towards this background. In other words, the surfaces 132 and 134 respectively constitute the lower and upper surfaces of the flange 13 when the flask 1 rests at its bottom 14 on a plane and horizontal surface S, as represented in FIGS. 10 to 13.
  • a pipette 200 is introduced into it, through its neck 1 1, as shown in FIG. 10.
  • the pipette 200 is removed and a closure device 20 is placed on the neck 12.
  • the device 20 comprises an elastomeric stopper 21 of shape adapted to be partially introduced into the neck 1 1, while resting on the face 132 of the 13.
  • the stopper 21 is in one piece and comprises a disk-shaped plate 21 1 intended to rest on the surface 132 as well as a hollow rod 212 intended to penetrate into the neck 11.
  • the cap 21 isolates the contents of the bottle 1 from the outside.
  • X21 is a central axis of symmetry of the plug 21. In mounted configuration of the cap 21 on the bottle 1, the axes X1 and X21 are merged.
  • the device 20 also comprises a cap 24 intended to cover and isolate the cap 21 and the neck 12 from the outside in the closed configuration of the closure device.
  • the cap 24 comprises a ring 25 and a cover 26 which are molded together and form a single piece as a cap 24. In other words, a continuity of material exists between the elements 25 and 26, within the cap 24 .
  • the ring 25 is provided with five locking teeth 253 under the surface 134 of the collar 13.
  • An outer peripheral skirt of the ring 25 and X25 is noted as a central axis of this ring.
  • This skirt is equipped, on its inner radial surface 251 A, teeth 253 with triangular section.
  • Each tooth 253 defines a blocking surface 253A perpendicular to the axis X25 and intended to bear against the surface 134 when the cap 24 is in place around the neck 12 of the bottle 1.
  • Each tooth 253 also defines a sliding surface 253B which is provided for sliding on a junction zone between the surface 132 and the outer radial surface of the flange 13 during the placement of the cap 24 on the neck 12.
  • the skirt 251 expands radially, elastically, during the passage of the teeth 253 at the collar 13, along the axis X1, before the teeth 253 come to lock under the flange 13, the surfaces 253A then coming opposite the surface 134 of the flange 13.
  • the teeth 253 constitute the locking means of the ring 25 on the neck 12 of the flask 1.
  • 253B surfaces are in portion of truncated cone and diverging downwards, which ensures the progressiveness of the elastic radial expansion of the skirt 251 to the passage of the flange 13.
  • the 254 is the annular portion of the ring 25 which partially covers the upper surface 213 of the plug 21 in the mounted configuration of the device 20 on the bottle 1, that is to say the surface of the plate 21 1 opposite the rod 212.
  • the portion 254 is perpendicular to the skirt 251 and pierced with five openings 255 for the passage of a molding drawer surfaces 253A.
  • the surface 213 is accessible through these openings 255.
  • Each opening 255 has, in cross section relative to the axis X25, a sufficient area to allow the passage of demolding pins 253A blocking surfaces of the teeth 253. This area is greater than the area of the surface 253A arranged next to the opening 255, in a direction parallel to the axis X25.
  • the lid 26 is circular and centered on an axis X26 which is coincident with the axis X25 when the elements 25 and 26 of the cap 24 are integral. 261 the outer radial edge of the cover 26 and D26 its maximum outside diameter.
  • Part 254 is provided with a circular central opening 256 centered on the axis X25 and whose diameter is noted d256.
  • the diameter D26 is strictly less than the diameter d256 and the edge 261 is disposed along the axes X25 and X26 together, at the edge 257 of the portion 254 which defines the orifice 256, radially inside this edge.
  • the elements 25 and 26 are connected by four bridges 27 which extend, radially with respect to the axes X25 and X26, between the edges 261 and 257 and which are in the form of trapezium with their smaller base 271 on the edge side 257.
  • the cover 26 also comprises a pin 262 centered on the axis X26 and turned towards the edge 251 B of the skirt 251 situated in the vicinity of the teeth 253. In other words, the pin 262 is turned towards the plug 21 in mounted configuration of the device 20.
  • the axial thickness of the bridges 27, that is to say their thickness measured parallel to the axis X26.
  • This thickness e27 is chosen so that the bridges 27 can be broken under the effect of a force E1 parallel to the axes X25 and X26 and directed towards the plug 21, that is to say towards the bottom 14 of a bottle 1 in which is mounted the device 20.
  • the value of the thickness e27 is chosen between 0.1 mm and 0.3 mm, preferably between 0.2 mm and 0.25 mm to allow effective immobilization of the cover 26 relative to the ring 25 before breaking of the saddles and an easy break under the effect of an axial force, when necessary.
  • FIGS. 2 to 4 show that, in the mounted configuration of the device 20 on the bottle 1, the pin 262 of the lid 26 exerts a deformation force on the central portion 214 of the plate 21 1 situated opposite the hollow interior volume of the stem 212.
  • This deformation is elastic, so that when the bridges 27 are broken, the elastic force E2 exerted by the plug 21 on the pin 262 of the lid 26 ejects it from the orifice 256.
  • the user does not have to pull the cover 26 to separate the parts 21 and 24 of the device 20 which remain in place on the bottle 1 since the elastic force E2 performs this function.
  • the lid 26 protrudes beyond the surface 258 with respect to the ring 25 over a height H measured parallel to the axis X26 which is at least two times greater than the thickness e27.
  • This surface is flat on an annular portion, with a central recess corresponding to the base of the pin 262.
  • the force E1 is exerted on the lid 26 to bring to the same axial level, along the axes X25 and X26 so merged, the annular portion of the surface 268 and the surface 258.
  • This induces a break suddenly of the bridges 27 insofar as this corresponds to an axial displacement of the cover 26 on the height H which is at least twice the thickness e27.
  • the bridges 27 can not withstand a shear force inducing a displacement twice their thickness.
  • a tapered tool such as a needle 300A from a hypodermic syringe into one of the lumens 28, in a position allowing access to the contents of the bottle 1 without removing the lid 26.
  • the width 28 is chosen less than 0.3 mm, preferably equal to 0.2 mm, while the height H28 is chosen greater than 0.15 mm, preferably equal to 0 , 2 mm.
  • a needle 300A can be introduced only in a direction generally parallel to the axes X25 and X26, a position in which it would abut against the surface 132 if it were driven deeply into the plate 21 1.
  • each opening 255 is bordered, radially on the inside and on the side opposite the surface 258, by a rib 259 which penetrates superficially into the surface 213.
  • a rib 259 which penetrates superficially into the surface 213.
  • the axial height H251 of the skirt 251, in its portion which projects beyond the surface 134, is chosen, as a function of the dimensions of the neck 12, so that the annular space E which remains between the edge 251 B and the body of the bottle 1 does not allow the introduction of a needle 300C that in a position where it abuts against the neck 12, without the possibility of acting on the teeth 253. This avoids fraudulent manipulation allows an unscrupulous user to remove the ring 25 of the collar 12.
  • the device 20 guarantees the integrity of the contents of the bottle 1.
  • the operation of the device 20 is as follows:
  • the lid 26 is separated from the bottle 1 by virtue of the elastic force E2 exerted on the lid by the stopper 21.
  • the material used to mold the cap 24 may be a polyoxymethylene or a polypropylene and it is chosen to induce a clean break at the level of the small bases 271 of the bridges 27.
  • the preferred breaking zones of the bridges 27 may be formed not in contact with the edge 257 but at a short radial distance therefrom.
  • the radial distance between these preferred breaking zones and the edge 257 is less than the radial distance between these preferred breaking zones and the attachment zones of the bridges 27 on the edge 261. This relationship is also verified in the case shown in the figures since, in this case, the axial distance between the small bases 271 and the edge 257 is zero, therefore less than the radial length of the bridges 27.
  • the number of jumpers used in the invention is not necessarily equal to four. It is chosen according to the desired resistance to the driving force of the cover 26 against the elastic force E2.
  • the bridges 27 may be replaced by a continuous breakable zone, in the form of a membrane.

Abstract

The invention relates to a stopping device (20) for a container (1) with a neck (12), said device comprising a stopper (21) and a plastic cap (24) that can cover both the neck and the stopper positioned in the neck. The cap (24) comprises a cover (26) and a ring (25) that is suitable for surrounding the stopper (21) and the neck (12) when mounted and provided with means (253) for locking onto the neck. The ring (25) and the cover (26) are produced as a single component and are connected by at least one part that is breakable by means of a force parallel to a central axis (X25) of the ring and directed towards the stopper (21). The cover (26) is provided with an element (262) for resting against the stopper (21). The breakable part consists of bridges (27) extending radially between an outer radial edge (261) of the cover (26) and an inner radial edge (257) of the ring (25). A channel (28) in an arc of a circle is defined between two adjacent bridges (27), the length of the outer radial edge (261) of the cover and the length of the inner radial edge (257) of the ring. Said channel has a radial width (28) of less than 0.3 mm and an axial height (H28) of more than 0.15 mm.

Description

Dispositif de bouchage et récipient équipé d'un tel dispositif  Clogging device and container equipped with such a device
L'invention a trait à un dispositif de bouchage pour un récipient, ce dispositif comprenant un bouchon prévu pour obturer le col du récipient, ainsi qu'une coiffe. L'invention a également trait à un récipient, par exemple un flacon pour médicament, équipé d'un tel dispositif de bouchage. The invention relates to a closure device for a container, this device comprising a plug designed to close the neck of the container, and a cap. The invention also relates to a container, for example a medicine bottle, equipped with such a closure device.
Dans le domaine des récipients pour médicaments, il est connu d'utiliser un flacon en verre pour conserver un principe actif sous forme de lyophilisât, de poudre ou de solution liquide. Un tel flacon doit être obturé de façon étanche afin de maintenir son contenu dans un état de conservation satisfaisant, jusqu'à sa date d'utilisation. Pour fermer hermétiquement un tel flacon, il est connu d'utiliser un dispositif de bouchage qui comprend un bouchon en élastomère de forme cylindrique prévu pour obturer le col du flacon. La fonction de ce bouchon est d'assurer une étanchéité la plus totale possible aux gaz, aux liquides et aux bactéries. Il est connu d'associer un tel bouchon avec une capsule métallique à opercule. L'ouverture du récipient a lieu en déchirant la capsule métallique par une traction sur l'opercule. Ceci peut s'avérer problématique dans la mesure où la capsule métallique, le plus souvent en aluminium, risque de se rompre, ce qui impose de devoir la retirer à la main d'où un risque de coupure et, le plus souvent, le recours à un petit outil de démontage.  In the field of drug containers, it is known to use a glass vial to preserve an active ingredient in the form of lyophilisate, powder or liquid solution. Such a bottle must be sealed in order to maintain its contents in a satisfactory state of preservation, until its date of use. To seal such a bottle, it is known to use a closure device which comprises a cylindrical elastomeric plug designed to close the neck of the bottle. The purpose of this cap is to ensure the most complete seal possible to gases, liquids and bacteria. It is known to associate such a cap with a metal cap operculum. The opening of the container takes place by tearing the metal cap by pulling on the lid. This can be problematic in that the metal capsule, usually aluminum, may break, which requires the need to remove the hand where a risk of cutting and, in most cases, recourse to a small disassembly tool.
II est connu WO-A-94/04424 d'utiliser une capsule en matière plastique qui est destinée à être immobilisée autour du bouchon pour l'isoler de l'extérieur. La structure multipartite de ce dispositif connu le rend onéreux. En outre, la capsule limite l'accès au bouchon qui ne peut pas être retiré, sauf à détruire la capsule, ce qui n'est pas le fonctionnement normal de ce dispositif.  It is known from WO-A-94/04424 to use a plastic cap which is intended to be immobilized around the cap to isolate it from the outside. The multipartite structure of this known device makes it expensive. In addition, the capsule limits access to the cap that can not be removed, except to destroy the capsule, which is not the normal operation of this device.
II est également connu de WO-A-2008/129144 d'utiliser un couvercle solidarisé à une clé de manœuvre d'une bague destinée à être verrouillée sur le col d'un flacon en verre. Ce couvercle est retiré par arrachement latéral lorsqu'on souhaite accéder au contenu du flacon. Cette manœuvre peut être délicate pour un utilisateur inexpérimenté ou une personne âgée.  It is also known from WO-A-2008/129144 to use a lid secured to an operating key of a ring intended to be locked on the neck of a glass bottle. This lid is removed by lateral tearing when it is desired to access the contents of the bottle. This maneuver can be tricky for an inexperienced user or an elderly person.
Par ailleurs, DE-A-195 32 980 enseigne de ménager une ligne de rupture continue entre un couvercle et une bague appartenant à la coiffe d'un dispositif de bouchage. Cette ligne continue peut s'avérer difficile à rompre pour un utilisateur inexpérimenté ou une personne âgée.  Furthermore, DE-A-195 32 980 teaches to provide a continuous line of rupture between a cover and a ring belonging to the cap of a closure device. This continuous line can be difficult to break for an inexperienced user or an elderly person.
C'est à ces inconvénients qu'entend plus particulièrement remédier l'invention en proposant un nouveau dispositif de bouchage qui est particulièrement simple et intuitif à mettre en œuvre et qui permet, entre autres, un retrait facile et rapide du couvercle pour un accès aisé au contenu d'un récipient. It is these drawbacks that the invention intends to remedy more particularly by proposing a new closure device which is particularly simple and intuitive to use. implement and which allows, among other things, an easy and quick removal of the lid for easy access to the contents of a container.
A cet effet, l'invention concerne un dispositif de bouchage pour un récipient pourvu d'un col, ce dispositif comprenant un bouchon et une coiffe en matière plastique apte à recouvrir à la fois le col et le bouchon en place dans le col, la coiffe comprenant une bague, apte à entourer le bouchon et le col en configuration montée et pourvue de moyens de verrouillage sur le col, ainsi qu'un couvercle. La bague et le couvercle sont réalisés dans une seule pièce monoblocet reliés par au moins une partie qui est sécable au moyen d'un effort parallèle à un axe central de la bague et dirigé vers le bouchon, alors que le couvercle est équipé d'un élément d'appui contre le bouchon. Ce dispositif de bouchage est caractérisé en ce que la partie sécable est formée par des pontets qui s'étendent radialement entre un bord radial externe du couvercle et un bord radial interne de la bague, en ce qu'une lumière en arc de cercle est définie entre deux pontets adjacents, le long du bord radial externe du couvercle et du bord radial interne de la bague et en ce que cette lumière a une largeur radiale inférieure à 0,3 mm et une hauteur axiale supérieure à 0,15 mm.  For this purpose, the invention relates to a closure device for a container provided with a neck, this device comprising a cap and a plastic cap capable of covering both the neck and the plug in place in the neck, the cap comprising a ring, adapted to surround the cap and collar in mounted configuration and provided with locking means on the neck, and a cover. The ring and the cover are made in one single piece connected by at least one part which is breakable by means of a force parallel to a central axis of the ring and directed towards the stopper, while the cover is equipped with a support element against the plug. This closure device is characterized in that the breakable portion is formed by bridges which extend radially between an outer radial edge of the cover and an inner radial edge of the ring, in that a circular arc light is defined between two adjacent bridges, along the outer radial edge of the cover and the inner radial edge of the ring and in that this light has a radial width less than 0.3 mm and an axial height greater than 0.15 mm.
Grâce à l'invention, le retrait du bouchon est particulièrement aisé puisqu'il suffit d'exercer sur celui-ci un effort dirigé vers le bouchon, c'est-à-dire en pratique vers le fond d'un flacon équipé du dispositif de bouchage, pour obtenir la rupture des pontets de la zone sécable. D'autre part, comme le couvercle repose contre le bouchon grâce à son élément d'appui, le couvercle subit un effort de déformation élastique de la part du bouchon, ce qui permet d'éjecter aisément le couvercle par rapport à la bague de la coiffe une fois la partie sécable rompue, en libérant ainsi l'accès au bouchon. L'invention procède d'une approche inhabituelle dans le domaine du conditionnement de médicament où les utilisateurs ont l'habitude de couvercles qui peuvent être retirés par un effort latéral (dit « flip off »), par un effort de traction (dit « tear off ») ou par un effort de rotation (dans le cas d'un bouchon vissé). Au contraire, le retrait du bouchon de l'invention nécessite seulement un effort de poussée en direction du fond du couvercle, ce qui est particulièrement simple à mettre en œuvre. En outre, les dimensions de la lumière définie entre deux pontets adjacents empêchent toute manipulation frauduleuse du contenu du récipient avant retrait du couvercle. En effet, ces dimensions sont incompatibles avec l'introduction d'une aiguille depuis l'extérieur du dispositif de bouchage jusque dans le col du récipient. Enfin, le fait de relier le couvercle à la bague par des pontets permet de calibrer l'effort axial nécessaire à leur rupture, avec une valeur inférieure à celle nécessaire à la rupture d'une ligne continue, ce qui facilite le retrait du couvercle. Selon des aspects avantageux mais non obligatoires de l'invention, un tel dispositif peut incorporer une ou plusieurs des caractéristiques suivantes prises dans toute combinaison techniquement admissible : Thanks to the invention, the removal of the cap is particularly easy since it is sufficient to exert on it a force directed towards the cap, that is to say in practice towards the bottom of a bottle equipped with the device. capping, to obtain the rupture of the bridges of the breakable zone. On the other hand, as the lid rests against the cap with its support member, the lid undergoes an elastic deformation force from the cap, which allows to easily eject the lid relative to the ring of the once the broken part is broken, thus freeing access to the cap. The invention proceeds from an unusual approach in the field of drug conditioning where users have the habit of covers that can be removed by a lateral force (called "flip off"), by a tensile force (called "tear"). off ") or by a rotational force (in the case of a screw cap). On the contrary, the withdrawal of the plug of the invention requires only a thrust force towards the bottom of the lid, which is particularly simple to implement. In addition, the dimensions of the light defined between two adjacent bridges prevent any fraudulent manipulation of the contents of the container before removal of the lid. Indeed, these dimensions are incompatible with the introduction of a needle from the outside of the closure device into the neck of the container. Finally, the fact of connecting the cover to the ring by bridges allows to calibrate the axial force required to break, with a value less than that required to break a continuous line, which facilitates the removal of the cover. According to advantageous but non-mandatory aspects of the invention, such a device may incorporate one or more of the following features taken in any technically permissible combination:
- Chaque pontet a une zone de rupture privilégiée qui est plus proche de la zone d'attache du pontet sur la bague que de la zone d'attache du pontet sur le couvercle.  - Each bridge has a preferred break zone that is closer to the attachment area of the bridge on the ring that the attachment area of the bridge on the lid.
- Les moyens de verrouillage comprennent des dents définissant chacune une surface de blocage perpendiculaire à un axe central et la bague et destinée à venir en appui contre une surface d'une collerette externe au col.  - The locking means comprise teeth each defining a locking surface perpendicular to a central axis and the ring and intended to bear against a surface of a collar external to the neck.
- Une partie annulaire de la bague, qui recouvre une surface supérieure du bouchon en configuration montée du dispositif de bouchage sur le récipient, est percée d'ouvertures de passage de broches pour démouler les surfaces de blocage des dents.  - An annular portion of the ring, which covers an upper surface of the plug in mounted configuration of the closure device on the container, is pierced with pin opening openings to unmold the locking surfaces of the teeth.
- La section transversale d'une ouverture de passage d'une broche de démoulage a une aire supérieure à l'aire de la surface du blocage située en regard de cette ouverture, selon une direction parallèle à l'axe central de la bague.  - The cross section of a passage opening of a demolding pin has an area greater than the area of the blocking surface located opposite this opening, in a direction parallel to the central axis of the ring.
- Chaque dent définit une surface de glissement contre la collerette, cette surface étant en portion de tronc de cône et divergente à l'opposé du couvercle par rapport à l'axe central de la bague.  Each tooth defines a sliding surface against the flange, this surface being in cone-truncated portion and diverging opposite the cover relative to the central axis of the ring.
- Les pontets ont une épaisseur axiale, mesurée parallèlement, à un axe central du couvercle, comprise entre 0.1 mm et 0.3 mm, de préférence entre 0.2 mm et 0.25 mm.  - The bridges have an axial thickness, measured parallel to a central axis of the lid, between 0.1 mm and 0.3 mm, preferably between 0.2 mm and 0.25 mm.
- Le couvercle s'étend, le long de l'axe central de la bague, en saillie par rapport à un bord de la bague opposé aux moyens de verrouillage. De préférence, le couvercle s'étend, par rapport au bord précité de la bague, sur une hauteur axiale supérieure ou égale à deux fois l'épaisseur axiale des pontets, de préférence supérieure ou égale à trois fois cette épaisseur, de préférence encore égale à quatre fois cette épaisseur.  - The cover extends along the central axis of the ring, projecting from an edge of the ring opposite the locking means. Preferably, the cover extends, with respect to the aforementioned edge of the ring, on an axial height greater than or equal to twice the axial thickness of the bridges, preferably greater than or equal to three times this thickness, more preferably equal to at four times that thickness.
- L'élément d'appui du couvercle sur le bouchon est constitué par un pion qui s'étend, le long de l'axe central du couvercle, en direction du bouchon, jusqu'au contact de celui-ci.  - The support element of the lid on the cap is constituted by a pin which extends along the central axis of the lid, in the direction of the plug, until contact therewith.
- En configuration montée du dispositif de bouchage sur un récipient, l'élément d'appui du couvercle exerce sur le bouchon un effort de déformation élastique d'une partie centrale du bouchon alignée sur le col du récipient.  - In mounted configuration of the closure device on a container, the support member of the lid exerts on the cap a force of elastic deformation of a central portion of the plug aligned on the neck of the container.
- A la rupture des pontets, le bouchon exerce sur l'élément d'appui un effort élastique d'éjection du bouchon, cet effort élastique résultant de l'effort de déformation élastique de la partie centrale du bouchon préalablement exercé par l'élément d'appui.  - At the rupture of the bridges, the cap exerts on the support member an elastic force of ejection of the plug, this elastic force resulting from the elastic deformation force of the central portion of the cap previously exerted by the element d 'support.
- Le couvercle est relié par la partie sécable à une partie annulaire de la bague qui est perpendiculaire à une jupe de cette bague, destinée à entourer le col du récipient et équipée des moyens de verrouillage, alors que la partie annulaire est pourvue d'au moins une ouverture et que chaque ouverture est bordée, du côté du bouchon, par une nervure destinée à pénétrer superficiellement le bouchon, radialement sur l'intérieur de l'ouverture. - The cover is connected by the breakable portion to an annular portion of the ring which is perpendicular to a skirt of this ring, intended to surround the neck of the container and equipped with locking means, while the annular portion is provided with at least one opening and each opening is bordered, on the plug side, by a rib for superficially penetrating the plug, radially on the inside of the opening .
L'invention concerne également un récipient, notamment un flacon pour médicament, qui est équipé d'un dispositif de bouchage tel que mentionné ci-dessus.  The invention also relates to a container, in particular a medicine bottle, which is equipped with a closure device as mentioned above.
L'invention sera mieux comprise et d'autres avantages de celle-ci apparaîtront plus clairement à la lecture de la description qui va suivre d'un mode de réalisation d'un dispositif de bouchage et d'un récipient conformes à son principe, donnée uniquement à titre d'exemple et faite en référence aux dessins annexés dans lesquels :  The invention will be better understood and other advantages thereof will appear more clearly on reading the following description of an embodiment of a closure device and a container according to its principle, given only by way of example and with reference to the appended drawings in which:
- la figure 1 est une vue en perspective d'un flacon pour médicament équipé d'un dispositif de bouchage conforme à l'invention,  FIG. 1 is a perspective view of a medication vial equipped with a closure device according to the invention,
- la figure 2 est une vue en perspective, avec arrachement partiel, de la partie supérieure du flacon de la figure 1 ,  FIG. 2 is a perspective view, partially broken away, of the upper part of the bottle of FIG. 1;
- la figure 3 est une coupe partielle selon le plan III à la figure 2 et représente des tentations d'intrusion sur le flacon,  FIG. 3 is a partial section along plane III in FIG. 2 and represents intrusion temptations on the bottle,
- la figure 4 est une coupe partielle selon le plan IV à la figure 2,  FIG. 4 is a partial section along plane IV in FIG. 2,
- la figure 5 est une coupe axiale éclatée, dans le même plan que la figure 3 du dispositif de bouchage seul,  FIG. 5 is an exploded axial section, in the same plane as FIG. 3 of the closure device alone,
- la figure 6 est une vue en perspective de la coiffe du dispositif de la figure 5, selon un premier angle,  FIG. 6 is a perspective view of the cap of the device of FIG. 5, at a first angle,
- la figure 7 est une vue de la coiffe de la figure 6 selon un autre angle,  FIG. 7 is a view of the cap of FIG. 6 according to another angle,
- la figure 8 est une vue en perspective du couvercle, après sa séparation d'avec la bague,  FIG. 8 is a perspective view of the lid, after its separation from the ring,
- la figure 9 est une vue de dessous du flacon de la figure 1 , à l'échelle de la figure 3, on y a représenté en lll-lll et IV-IV les plans de coupe des figures 3 et 4, FIG. 9 is a view from below of the bottle of FIG. 1, to the scale of FIG. 3, there is shown in III-III and IV-IV the sectional planes of FIGS. 3 and 4,
- les figures 10 à 13 représentent plusieurs étapes successives d'utilisation du flacon des figures précédentes et FIGS. 10 to 13 represent several successive stages of use of the bottle of the preceding figures and
- la figure 14 est une représentation comparable à la figure 12 et correspond à une autre façon d'utiliser le flacon.  - Figure 14 is a representation similar to Figure 12 and corresponds to another way of using the bottle.
Le flacon 1 représenté sur les figures est en verre et il comprend un goulot 1 1 qui est défini par un col 12 présentant une collerette externe 13. On note X1 l'axe de symétrie du flacon 1 qui est également un axe central du col 12 et de la collerette 13. On note 14 le fond du flacon 1 qui est opposé au goulot 1 1 . On note respectivement 132 et 134 les surfaces de la collerette 13 qui sont orientées à l'opposé du fond 14 et en direction de ce fond. En d'autres termes, les surfaces 132 et 134 constituent respectivement les surfaces inférieure et supérieure de la collerette 13 lorsque le flacon 1 repose par son fond 14 sur une surface S, plane et horizontale, comme représenté aux figures 10 à 13. The bottle 1 shown in the figures is made of glass and comprises a neck 1 1 which is defined by a neck 12 having an outer collar 13. X1 is the axis of symmetry of the bottle 1 which is also a central axis of the neck 12 and flange 13. Note 14 the bottom of the bottle 1 which is opposite the neck 1 1. 132 and 134 are respectively noted the surfaces of the flange 13 which are oriented opposite the bottom 14 and towards this background. In other words, the surfaces 132 and 134 respectively constitute the lower and upper surfaces of the flange 13 when the flask 1 rests at its bottom 14 on a plane and horizontal surface S, as represented in FIGS. 10 to 13.
Lorsqu'il convient de remplir le flacon 1 , une pipette 200 est introduite dans celui- ci, à travers son goulot 1 1 , comme représenté à la figure 10. Lorsqu'une quantité prédéterminée de produit a été introduite dans le flacon 1 , la pipette 200 est retirée et un dispositif de bouchage 20 est mis en place sur le col 12. Le dispositif 20 comprend un bouchon en élastomère 21 de forme adaptée pour être partiellement introduit dans le goulot 1 1 , tout en reposant sur la face 132 de la collerette 13. Le bouchon 21 est monobloc et comprend un plateau 21 1 en forme de disque destiné à reposer sur la surface 132 ainsi qu'une tige creuse 212 destinée à pénétrer dans le goulot 1 1 . Une fois en place sur le col 12, le bouchon 21 isole le contenu du flacon 1 de l'extérieur. On note X21 un axe central de symétrie du bouchon 21 . En configuration montée du bouchon 21 sur le flacon 1 , les axes X1 et X21 sont confondus.  When it is necessary to fill the bottle 1, a pipette 200 is introduced into it, through its neck 1 1, as shown in FIG. 10. When a predetermined quantity of product has been introduced into the bottle 1, the pipette 200 is removed and a closure device 20 is placed on the neck 12. The device 20 comprises an elastomeric stopper 21 of shape adapted to be partially introduced into the neck 1 1, while resting on the face 132 of the 13. The stopper 21 is in one piece and comprises a disk-shaped plate 21 1 intended to rest on the surface 132 as well as a hollow rod 212 intended to penetrate into the neck 11. Once in place on the neck 12, the cap 21 isolates the contents of the bottle 1 from the outside. X21 is a central axis of symmetry of the plug 21. In mounted configuration of the cap 21 on the bottle 1, the axes X1 and X21 are merged.
Le dispositif 20 comprend également une coiffe 24 destinée à recouvrir et à isoler le bouchon 21 et le col 12 de l'extérieur en configuration fermée du dispositif de bouchage.  The device 20 also comprises a cap 24 intended to cover and isolate the cap 21 and the neck 12 from the outside in the closed configuration of the closure device.
La coiffe 24 comprend une bague 25 et un couvercle 26 qui sont moulés ensemble et forment une pièce monobloc en tant que coiffe 24. En d'autres termes, une continuité de matière existe entre les éléments 25 et 26, au sein de la coiffe 24.  The cap 24 comprises a ring 25 and a cover 26 which are molded together and form a single piece as a cap 24. In other words, a continuity of material exists between the elements 25 and 26, within the cap 24 .
La bague 25 est pourvue de cinq dents 253 de verrouillage sous la surface 134 de la collerette 13.  The ring 25 is provided with five locking teeth 253 under the surface 134 of the collar 13.
On note 251 une jupe périphérique externe de la bague 25 et X25 un axe central de cette bague. Cette jupe est équipée, sur sa surface radiale interne 251 A, des dents 253 à section triangulaire. Chaque dent 253 définit une surface de blocage 253A perpendiculaire à l'axe X25 et destinée à venir en appui contre la surface 134 lorsque la coiffe 24 est en place autour du col 12 du flacon 1 . Chaque dent 253 définit également une surface de glissement 253B qui est prévue pour glisser sur une zone de jonction entre la surface 132 et la surface radiale externe de la collerette 13 lors de la mise en place de la coiffe 24 sur le col 12.  An outer peripheral skirt of the ring 25 and X25 is noted as a central axis of this ring. This skirt is equipped, on its inner radial surface 251 A, teeth 253 with triangular section. Each tooth 253 defines a blocking surface 253A perpendicular to the axis X25 and intended to bear against the surface 134 when the cap 24 is in place around the neck 12 of the bottle 1. Each tooth 253 also defines a sliding surface 253B which is provided for sliding on a junction zone between the surface 132 and the outer radial surface of the flange 13 during the placement of the cap 24 on the neck 12.
Lors de cette mise en place, la jupe 251 s'expand radialement, de façon élastique, lors du passage des dents 253 au niveau de la collerette 13, le long de l'axe X1 , avant que les dents 253 viennent se verrouiller sous la collerette 13, les surfaces 253A venant alors en regard de la surface 134 de la collerette 13. Ainsi, les dents 253 constituent les moyens de verrouillage de la bague 25 sur le col 12 du flacon 1 . Les surfaces 253B sont en portion de tronc de cône et divergentes vers le bas, ce qui assure la progressivité de l'expansion radiale élastique de la jupe 251 au passage de la collerette 13. During this installation, the skirt 251 expands radially, elastically, during the passage of the teeth 253 at the collar 13, along the axis X1, before the teeth 253 come to lock under the flange 13, the surfaces 253A then coming opposite the surface 134 of the flange 13. Thus, the teeth 253 constitute the locking means of the ring 25 on the neck 12 of the flask 1. 253B surfaces are in portion of truncated cone and diverging downwards, which ensures the progressiveness of the elastic radial expansion of the skirt 251 to the passage of the flange 13.
On note 254 la partie annulaire de la bague 25 qui recouvre partiellement la surface supérieure 213 du bouchon 21 en configuration montée du dispositif 20 sur le flacon 1 , c'est-à-dire la surface du plateau 21 1 opposée à la tige 212. La partie 254 est perpendiculaire à la jupe 251 et percée de cinq ouvertures 255 de passage d'un tiroir de moulage des surfaces 253A. La surface 213 est accessible à travers ces ouvertures 255.  254 is the annular portion of the ring 25 which partially covers the upper surface 213 of the plug 21 in the mounted configuration of the device 20 on the bottle 1, that is to say the surface of the plate 21 1 opposite the rod 212. The portion 254 is perpendicular to the skirt 251 and pierced with five openings 255 for the passage of a molding drawer surfaces 253A. The surface 213 is accessible through these openings 255.
Chaque ouverture 255 présente, en section transversale par rapport à l'axe X25, une aire suffisante pour permettre le passage de broches de démoulage des surfaces de blocage 253A des dents 253. Cette aire est donc supérieure à l'aire de la surface 253A disposée en regard de l'ouverture 255, selon une direction parallèle à l'axe X25.  Each opening 255 has, in cross section relative to the axis X25, a sufficient area to allow the passage of demolding pins 253A blocking surfaces of the teeth 253. This area is greater than the area of the surface 253A arranged next to the opening 255, in a direction parallel to the axis X25.
Le couvercle 26 est circulaire et centré sur un axe X26 qui est confondu avec l'axe X25 lorsque les éléments 25 et 26 de la coiffe 24 sont solidaires. On note 261 le bord radial externe du couvercle 26 et D26 son diamètre extérieur maximum.  The lid 26 is circular and centered on an axis X26 which is coincident with the axis X25 when the elements 25 and 26 of the cap 24 are integral. 261 the outer radial edge of the cover 26 and D26 its maximum outside diameter.
La partie 254 est pourvue d'un orifice central circulaire 256 centré sur l'axe X25 et dont on note d256 le diamètre.  Part 254 is provided with a circular central opening 256 centered on the axis X25 and whose diameter is noted d256.
Le diamètre D26 est strictement inférieur au diamètre d256 et le bord 261 est disposé, le long des axes X25 et X26 confondus, à hauteur du bord 257 de la partie 254 qui définit l'orifice 256, radialement à l'intérieur de ce bord.  The diameter D26 is strictly less than the diameter d256 and the edge 261 is disposed along the axes X25 and X26 together, at the edge 257 of the portion 254 which defines the orifice 256, radially inside this edge.
Lors de la fabrication de la coiffe 24 en une pièce monobloc, les éléments 25 et 26 sont reliés par quatre pontets 27 qui s'étendent, radialement par rapport aux axes X25 et X26, entre les bords 261 et 257 et qui sont en forme de trapèze avec leur plus petite base 271 du côté du bord 257.  During the manufacture of the cap 24 in a single piece, the elements 25 and 26 are connected by four bridges 27 which extend, radially with respect to the axes X25 and X26, between the edges 261 and 257 and which are in the form of trapezium with their smaller base 271 on the edge side 257.
Le couvercle 26 comprend également un pion 262 centré sur l'axe X26 et tourné vers le bord 251 B de la jupe 251 situé au voisinage des dents 253. En d'autres termes, le pion 262 est tourné vers le bouchon 21 en configuration montée du dispositif 20.  The cover 26 also comprises a pin 262 centered on the axis X26 and turned towards the edge 251 B of the skirt 251 situated in the vicinity of the teeth 253. In other words, the pin 262 is turned towards the plug 21 in mounted configuration of the device 20.
On note e27 l'épaisseur axiale des pontets 27, c'est-à-dire leur épaisseur mesurée parallèlement à l'axe X26. Cette épaisseur e27 est choisie pour que les pontets 27 puissent être rompus sous l'effet d'un effort E1 parallèle aux axes X25 et X26 et dirigé vers le bouchon 21 , c'est-à-dire vers le fond 14 d'un flacon 1 sur lequel est monté le dispositif 20. En pratique, la valeur de l'épaisseur e27 est choisie entre 0.1 mm et 0.3 mm, de préférence entre 0.2 mm et 0.25 mm pour permettre une immobilisation efficace du couvercle 26 par rapport à la bague 25 avant rupture des pontets et une rupture aisée sous l'effet d'un effort axial, lorsque nécessaire. Ainsi, lorsque le dispositif 20 a été mis en place sur un flacon 1 , c'est-à-dire lorsqu'on est dans la configuration des figures 1 à 4 et 12, il est possible d'exercer sur le bouchon 26 l'effort E1 , ce qui se traduit par un effort de cisaillement sur les pontets 27, lesquels se rompent au niveau de leurs petites bases respectives 271 . Note e27 the axial thickness of the bridges 27, that is to say their thickness measured parallel to the axis X26. This thickness e27 is chosen so that the bridges 27 can be broken under the effect of a force E1 parallel to the axes X25 and X26 and directed towards the plug 21, that is to say towards the bottom 14 of a bottle 1 in which is mounted the device 20. In practice, the value of the thickness e27 is chosen between 0.1 mm and 0.3 mm, preferably between 0.2 mm and 0.25 mm to allow effective immobilization of the cover 26 relative to the ring 25 before breaking of the saddles and an easy break under the effect of an axial force, when necessary. Thus, when the device 20 has been put in place on a bottle 1, that is to say when it is in the configuration of FIGS. 1 to 4 and 12, it is possible to exert on the plug 26 the E1 effort, which results in a shear force on the bridges 27, which break at their respective small bases 271.
On remarque aux figures 2 à 4 que, en configuration montée du dispositif 20 sur le flacon 1 , le pion 262 du couvercle 26 exerce un effort de déformation de la partie centrale 214 du plateau 21 1 située en regard du volume intérieur creux de la tige 212. Cette déformation est élastique, de sorte que, lorsque les pontets 27 sont rompus, l'effort élastique E2 exercé par le bouchon 21 sur le pion 262 du couvercle 26 éjecte celui-ci de l'orifice 256. En d'autres termes, l'utilisateur n'a pas à tirer sur le couvercle 26 pour le séparer des parties 21 et 24 du dispositif 20 qui demeurent en place sur le flacon 1 puisque l'effort élastique E2 remplit cette fonction. On remarque que l'effort E2 existe avant la rupture des pontets 27 puisque le pion 262 déforme élastiquement la partie 214 lorsque le dispositif 20 est en place sur le flacon 1 , ce qui procède d'une approche différente de celle de DE-A-195 32 980 où, avant rupture de la zone sécable, le couvercle ne déforme pas le bouchon. En jouant sur les dimensions du pion 262, il est possible de calibrer la déformation élastique de la partie 214 préalable à la rupture des pontets et, en conséquence, l'intensité de l'effort E2.  FIGS. 2 to 4 show that, in the mounted configuration of the device 20 on the bottle 1, the pin 262 of the lid 26 exerts a deformation force on the central portion 214 of the plate 21 1 situated opposite the hollow interior volume of the stem 212. This deformation is elastic, so that when the bridges 27 are broken, the elastic force E2 exerted by the plug 21 on the pin 262 of the lid 26 ejects it from the orifice 256. In other words the user does not have to pull the cover 26 to separate the parts 21 and 24 of the device 20 which remain in place on the bottle 1 since the elastic force E2 performs this function. Note that the force E2 exists before the breaking of the bridges 27 since the pin 262 elastically deforms the portion 214 when the device 20 is in place on the bottle 1, which proceeds from a different approach to that of DE-A- 195 32 980 where, before rupture of the breakable zone, the lid does not deform the plug. By adjusting the dimensions of the pin 262, it is possible to calibrate the elastic deformation of the portion 214 prior to breaking the jumpers and, consequently, the intensity of the effort E2.
On note 258 la surface annulaire supérieure de la partie 254. Cette surface 258 constitue le bord de la bague 25 qui est opposé aux dents de verrouillage 253. En configuration montée du dispositif 20, telle que représentée notamment aux figures 2 à 4, le couvercle 26 dépasse au-delà de la surface 258 par rapport à la bague 25 sur une hauteur H mesurée parallèlement à l'axe X26 qui est au moins deux fois supérieure à l'épaisseur e27.  258 is the upper annular surface of the portion 254. This surface 258 constitutes the edge of the ring 25 which is opposite the locking teeth 253. In the mounted configuration of the device 20, as shown in particular in Figures 2 to 4, the lid 26 protrudes beyond the surface 258 with respect to the ring 25 over a height H measured parallel to the axis X26 which is at least two times greater than the thickness e27.
On note par ailleurs 268 la surface du couvercle 26 qui est opposée au pion 262. Note 268 the surface of the lid 26 which is opposite the pin 262.
Cette surface est plane sur une partie annulaire, avec un renfoncement central correspondant à la base du pion 262. This surface is flat on an annular portion, with a central recess corresponding to the base of the pin 262.
En pratique, l'effort E1 est exercé sur le couvercle 26 jusqu'à amener au même niveau axial, le long des axes X25 et X26 alors confondus, la partie annulaire de la surface 268 et la surface 258. Ceci induit une rupture à coup sûr des pontets 27 dans la mesure où ceci correspond à un déplacement axial du couvercle 26 sur la hauteur H qui est au moins deux fois supérieure à l'épaisseur e27. En effet, les pontets 27 ne peuvent pas résister à un effort de cisaillement induisant un déplacement deux fois supérieur à leur épaisseur. En pratique, on majore la valeur 2 du rapport H/e27 d'un coefficient de sécurité, de telle sorte que ce rapport est supérieur ou égal à trois. Des résultats particulièrement satisfaisants peuvent être obtenus avec un rapport H/e27 égal à quatre. In practice, the force E1 is exerted on the lid 26 to bring to the same axial level, along the axes X25 and X26 so merged, the annular portion of the surface 268 and the surface 258. This induces a break suddenly of the bridges 27 insofar as this corresponds to an axial displacement of the cover 26 on the height H which is at least twice the thickness e27. Indeed, the bridges 27 can not withstand a shear force inducing a displacement twice their thickness. In practice, we increase the value 2 of the ratio H / e27 of a coefficient of security, so that this ratio is greater than or equal to three. Particularly satisfactory results can be obtained with a ratio H / e27 equal to four.
Comme il ressort plus particulièrement de la figure 1 1 , quatre lumières en arc de cercle 28 sont définies entre les bords 261 et 257, entre deux pontets 27 adjacents. Avant retrait du couvercle 26, ces lumières constituent la seule partie non pleine de l'orifice 256. On note 28 la largeur de ces lumières mesurées, entre les bords 261 et 257, radialement par rapport aux axes X25 et X26. On note H28 la hauteur axiale de ces lumières mesurée parallèlement aux axes X25 et X26.  As is more particularly apparent from Figure 1 1, four arcuate lights 28 are defined between the edges 261 and 257, between two bridges 27 adjacent. Before removing the cover 26, these lights are the only non-full portion of the orifice 256. Note 28 the width of these lights measured between the edges 261 and 257, radially relative to the axes X25 and X26. Note H28 the axial height of these lights measured parallel to the axes X25 and X26.
Ces dimensions 28 et H28 sont choisies de façon à empêcher l'introduction d'un outil effilé tel qu'une aiguille 300A d'une seringue hypodermique dans l'une des lumières 28, dans une position permettant d'accéder au contenu du flacon 1 sans retirer le couvercle 26. Pour ce faire, la largeur 28 est choisie inférieure à 0,3 mm, de préférence égale à 0,2 mm, alors que la hauteur H28 est choisie supérieure à 0,15 mm, de préférence égale à 0,2 mm. Comme montré à la figure 3, une aiguille 300A ne peut être introduite que dans une direction globalement parallèle aux axes X25 et X26, position dans laquelle elle viendrait buter contre la surface 132 si elle était enfoncée profondément dans le plateau 21 1 .  These dimensions 28 and 28 are chosen so as to prevent the insertion of a tapered tool such as a needle 300A from a hypodermic syringe into one of the lumens 28, in a position allowing access to the contents of the bottle 1 without removing the lid 26. To do this, the width 28 is chosen less than 0.3 mm, preferably equal to 0.2 mm, while the height H28 is chosen greater than 0.15 mm, preferably equal to 0 , 2 mm. As shown in FIG. 3, a needle 300A can be introduced only in a direction generally parallel to the axes X25 and X26, a position in which it would abut against the surface 132 if it were driven deeply into the plate 21 1.
Pour protéger le contenu du flacon 1 également à rencontre d'une tentative de manipulation frauduleuse, chaque ouverture 255 est bordée, radialement sur l'intérieur et du côté opposé à la surface 258, par une nervure 259 qui pénètre superficiellement dans la surface 213. Ainsi, comme représenté en partie supérieure gauche de la figure 3, l'introduction d'une aiguille 300B dans l'une des ouvertures 255 ne permet pas d'accéder au contenu du flacon 1 , à travers le bouchon interne 21 , alors que les ouvertures ont chacune une section transversale d'aire relativement importante pour le passage des broches de démoulage, comme expliqué ci-dessus. On comprend que la problématique de protection du contenu du flacon 1 par rapport à une manipulation frauduleuse au moyen de l'aiguille 300B est liée à l'existence et à la taille des ouvertures 255 qui sont nécessaires pour mouler les surfaces 253A des dents 253, lesquelles constituent des moyens de verrouillage efficace sur le col 12, à la différence du bourrelet connu de DE-A- 195 32 980. En d'autres termes, la présence et la fonction de la nervure 259 résulte indirectement de l'utilisation des dents 253.  To protect the contents of the bottle 1 also against an attempt at fraudulent manipulation, each opening 255 is bordered, radially on the inside and on the side opposite the surface 258, by a rib 259 which penetrates superficially into the surface 213. Thus, as shown in the upper left portion of FIG. 3, the introduction of a needle 300B into one of the openings 255 does not allow access to the contents of the bottle 1, through the internal plug 21, while the apertures each have a relatively large cross-sectional area for the passage of the demolding pins, as explained above. It will be understood that the problem of protecting the contents of the bottle 1 with respect to a fraudulent manipulation by means of the needle 300B is related to the existence and the size of the openings 255 which are necessary for molding the surfaces 253A of the teeth 253, which constitute effective locking means on the neck 12, unlike the known bead of DE-A-195 32 980. In other words, the presence and function of the rib 259 results indirectly from the use of the teeth 253.
Par ailleurs, la hauteur axiale H251 de la jupe 251 , dans sa partie qui dépasse en deçà de la surface 134 est choisie, en fonction des dimensions du col 12 de telle sorte que l'espace annulaire E qui subsiste entre le bord 251 B et le corps du flacon 1 ne permet l'introduction d'une aiguille 300C que dans une position où elle vient en butée contre le col 12, sans possibilité d'agir sur les dents 253. On évite ainsi qu'une manipulation frauduleuse permette à un utilisateur indélicat de retirer la bague 25 du col 12. Moreover, the axial height H251 of the skirt 251, in its portion which projects beyond the surface 134, is chosen, as a function of the dimensions of the neck 12, so that the annular space E which remains between the edge 251 B and the body of the bottle 1 does not allow the introduction of a needle 300C that in a position where it abuts against the neck 12, without the possibility of acting on the teeth 253. This avoids fraudulent manipulation allows an unscrupulous user to remove the ring 25 of the collar 12.
Ainsi, une fois en place sur le col 12, le dispositif 20 garantit l'intégrité du contenu du flacon 1 .  Thus, once in place on the neck 12, the device 20 guarantees the integrity of the contents of the bottle 1.
Le fonctionnement du dispositif 20 est le suivant :  The operation of the device 20 is as follows:
Lorsque ce dispositif est en place sur le flacon 1 et après mise en place du bouchon 31 et de la coiffe 24 sur le flacon 1 , comme représenté par les flèches F1 et F2 à la figure 1 1 , et lorsqu'on exerce un effort E1 parallèle aux axes X25 et X26 et amenant la partie annulaire de la surface 268 au niveau de la surface 258, les pontets 27 sont rompus, sans avoir à exercer un effort de rotation ou de traction, et on parvient dans la configuration de la figure 13 où le bouchon 26 est séparé de la bague 25, en laissant un accès à la surface supérieure 213 du bouchon 21 , à travers l'orifice 256.  When this device is in place on the bottle 1 and after placing the stopper 31 and the cap 24 on the bottle 1, as represented by the arrows F1 and F2 in Figure 1 1, and when exerting a force E1 parallel to the X25 and X26 axes and bringing the annular portion of the surface 268 at the surface 258, the bridges 27 are broken, without having to exert a force of rotation or traction, and one arrives in the configuration of Figure 13 where the plug 26 is separated from the ring 25, leaving access to the upper surface 213 of the plug 21, through the orifice 256.
La séparation du couvercle 26 d'avec le flacon 1 a lieu grâce à l'effort élastique E2 exercé sur le couvercle par le bouchon 21 .  The lid 26 is separated from the bottle 1 by virtue of the elastic force E2 exerted on the lid by the stopper 21.
Après retrait du couvercle, il est possible d'utiliser l'aiguille d'une seringue pour injecter dans ce flacon un liquide de reconstitution d'un médicament, puis y prélever le médicament reconstitué.  After removal of the lid, it is possible to use the needle of a syringe to inject into the bottle a drug reconstitution liquid, and then take the reconstituted drug.
En variante, et comme représenté à la figure 14, il est possible de poser le flacon 1 équipé du dispositif 20 à l'envers sur une surface plane S et d'exercer sur le fond 14 du flacon 1 un effort E1 ' dirigé vers la surface S. Ceci a également pour effet de déplacer le couvercle 26 vers le bouchon 1 et de rompre les pontets. Cette deuxième façon d'appliquer l'effort sur le couvercle 26 revient à utiliser un effort de réaction E1 exercé par la surface S sur laquelle repose le dispositif 20 pour rompre les pontets 27.  Alternatively, and as shown in Figure 14, it is possible to place the bottle 1 equipped with the device 20 upside down on a flat surface S and to exert on the bottom 14 of the bottle 1 a force E1 'directed towards the surface S. This also has the effect of moving the lid 26 to the cap 1 and break the jumpers. This second way of applying the force on the lid 26 amounts to using a reaction force E1 exerted by the surface S on which the device 20 rests to break the bridges 27.
Le matériau utilisé pour mouler la coiffe 24 peut être un polyoxyméthylène ou un polypropylène et il est choisi pour induire une rupture nette au niveau des petites bases 271 des pontets 27.  The material used to mold the cap 24 may be a polyoxymethylene or a polypropylene and it is chosen to induce a clean break at the level of the small bases 271 of the bridges 27.
On remarque à la figure 13 que, comme les petites bases 271 des pontets 27 sont situées sur le bord 257, le pontet 27 ne laisse pas subsister d'irrégularité sur ce bord après retrait du bouchon 26.  Note in Figure 13 that, since the small bases 271 of the bridges 27 are located on the edge 257, the bridge 27 does not leave an irregularity on this edge after removal of the plug 26.
Selon une variante non représentée de l'invention, les zones de rupture privilégiée des pontets 27 peuvent être ménagées non pas au contact du bord 257 mais à faible distance radiale de celui-ci. En pratique, la distance radiale entre ces zones de rupture privilégiée et le bord 257 est inférieure à la distance radiale entre ces zones de rupture privilégiée et les zones d'attache des pontets 27 sur le bord 261 . Cette relation est également vérifiée dans le cas représenté sur les figures puisque, dans ce cas, la distance axiale entre les petites bases 271 et le bord 257 est nulle, donc inférieure à la longueur radiale des pontets 27. According to a not shown variant of the invention, the preferred breaking zones of the bridges 27 may be formed not in contact with the edge 257 but at a short radial distance therefrom. In practice, the radial distance between these preferred breaking zones and the edge 257 is less than the radial distance between these preferred breaking zones and the attachment zones of the bridges 27 on the edge 261. This relationship is also verified in the case shown in the figures since, in this case, the axial distance between the small bases 271 and the edge 257 is zero, therefore less than the radial length of the bridges 27.
Le nombre de pontets utilisés dans l'invention n'est pas forcement égal à quatre. Il est choisi en fonction de la résistance souhaitée à l'effort d'enfoncement du couvercle 26 à rencontre de l'effort élastique E2.  The number of jumpers used in the invention is not necessarily equal to four. It is chosen according to the desired resistance to the driving force of the cover 26 against the elastic force E2.
En variante, quel que soit leur nombre, les pontets 27 peuvent être remplacés par une zone sécable continue, en forme de membrane.  As a variant, regardless of their number, the bridges 27 may be replaced by a continuous breakable zone, in the form of a membrane.

Claims

REVENDICATIONS
1 . - Dispositif de bouchage (20) pour un récipient (1 ) pourvu d'un col (12), ce dispositif comprenant un bouchon (21 ) et une coiffe (24) en matière plastique apte à recouvrir à la fois le col et le bouchon en place dans le col, la coiffe comprenant une bague (25), apte à entourer le bouchon et le col en configuration montée et pourvue de moyens (253) de verrouillage sur le col, ainsi qu'un couvercle (26), dans lequel, 1. - Closing device (20) for a container (1) provided with a neck (12), this device comprising a cap (21) and a cap (24) of plastic material capable of covering both the neck and the stopper in place in the neck, the cap comprising a ring (25), able to surround the cap and the neck in mounted configuration and provided with means (253) for locking on the neck, and a cover (26), in which ,
- la bague (25) et le couvercle (26) sont réalisés dans une seule pièce monobloc,  the ring (25) and the cover (26) are made in a single piece,
- la bague (25) et le couvercle (26) sont reliés par au moins une partie (27) qui est sécable au moyen d'un effort (E1 ) parallèle à un axe central (X25) de la bague et dirigé vers le bouchon (21 ) et  - The ring (25) and the cover (26) are connected by at least one part (27) which is breakable by means of a force (E1) parallel to a central axis (X25) of the ring and directed towards the stopper (21) and
- le couvercle est équipé d'un élément (262) d'appui contre le bouchon (21 ). caractérisé en ce que  - The lid is equipped with a member (262) for bearing against the plug (21). characterized in that
- la partie sécable est formée par des pontets (27) qui s'étendent radialement entre un bord radial externe (261 ) du couvercle (26) et un bord radial interne (257) de la bague (25) et  - the breakable portion is formed by bridges (27) which extend radially between an outer radial edge (261) of the cover (26) and an inner radial edge (257) of the ring (25) and
une lumière (28) en arc de cercle est définie entre deux pontets adjacents (27), le long du bord radial externe (261 ) du couvercle et du bord radial interne (257) de la bague et en ce que cette lumière a une largeur radiale ( 28) inférieure à an arcuate lumen (28) is defined between two adjacent bridges (27), along the outer radial edge (261) of the cover and the inner radial edge (257) of the ring and in that this light has a width radial (28) less than
0,3 mm et une hauteur axiale (H28) supérieure à 0,15 mm. 0.3 mm and an axial height (H28) greater than 0.15 mm.
2. - Dispositif selon la revendication 1 , caractérisé en ce que chaque pontet (27) a une zone de rupture privilégiée (271 ) qui est plus proche de la zone d'attache du pontet sur la bague (25) que de la zone d'attache du pontet sur le couvercle (26).  2. - Device according to claim 1, characterized in that each bridge (27) has a preferred breaking zone (271) which is closer to the attachment zone of the bridge on the ring (25) than the zone d attachment of the bridge on the lid (26).
3.- Dispositif selon l'une des revendications précédentes, caractérisé en ce que les moyens de verrouillage comprennent des dents (253) définissant chacune une surface de blocage (253A) perpendiculaire à un axe central (X25) et la bague (25) et destinée à venir en appui contre une surface (134) d'une collerette (13) externe au col (12).  3.- Device according to one of the preceding claims, characterized in that the locking means comprise teeth (253) each defining a locking surface (253A) perpendicular to a central axis (X25) and the ring (25) and intended to bear against a surface (134) of a flange (13) external to the neck (12).
4. - Dispositif selon la revendication 3, caractérisé en ce qu'une partie annulaire (254) de la bague (25), qui recouvre une surface supérieure (213) du bouchon (21 ) en configuration montée du dispositif de bouchage (20) sur le récipient (1 ), est percée d'ouvertures (255) de passage de broches de démoulage des surfaces de blocage (253A) des dents (253).  4. - Device according to claim 3, characterized in that an annular portion (254) of the ring (25), which covers an upper surface (213) of the plug (21) in the mounted configuration of the closure device (20). on the container (1) is pierced with openings (255) for the demolding pin passage of the locking surfaces (253A) of the teeth (253).
5. - Dispositif selon la revendication 4, caractérisé en ce que la section transversale d'une ouverture (255) de passage d'une broche de démoulage a une aire supérieure à l'aire de la surface du blocage (253A) située en regard de cette ouverture, selon une direction parallèle à l'axe central (X25) de la bague. 5. - Device according to claim 4, characterized in that the cross section of an opening (255) for passage of a release pin has an area greater than the area of the blocking surface (253A) situated opposite this opening, in a direction parallel to the central axis (X25) of the ring.
6. - Dispositif selon l'une des revendications 3 à 5, caractérisé en ce que chaque dent (253) définit une surface (253B) de glissement contre la collerette, cette surface étant en portion de tronc de cône et divergente à l'opposé du couvercle (26) par rapport à l'axe central (X25) de la bague (25).  6. - Device according to one of claims 3 to 5, characterized in that each tooth (253) defines a surface (253B) of sliding against the flange, this surface being cone portion truncated and divergent opposite the cover (26) relative to the central axis (X25) of the ring (25).
7. - Dispositif selon l'une des revendications précédentes, caractérisé en ce que les pontets (27) ont une épaisseur axiale (e27), mesurée parallèlement, à un axe central (X26) du couvercle (26), comprise entre 0.1 mm et 0.3 mm, de préférence entre 0.2 mm et 0.25 mm.  7. - Device according to one of the preceding claims, characterized in that the bridges (27) have an axial thickness (e27), measured parallel to a central axis (X26) of the cover (26), between 0.1 mm and 0.3 mm, preferably between 0.2 mm and 0.25 mm.
8. - Dispositif selon l'une des revendications précédentes, caractérisé en ce que le couvercle (26) s'étend, le long de l'axe central de la bague (X25), en saillie par rapport à un bord (258) de la bague opposé aux moyens de verrouillage (253).  8. - Device according to one of the preceding claims, characterized in that the cover (26) extends along the central axis of the ring (X25), projecting from an edge (258) of the ring opposite the locking means (253).
9. - Dispositif selon la revendication 8, caractérisé en ce que le couvercle (26) s'étend, par rapport au bord de la bague (258), sur une hauteur axiale (H) supérieure ou égale à deux fois l'épaisseur axiale (e27) des pontets (27), de préférence supérieure ou égale à trois fois cette épaisseur, de préférence encore égale à quatre fois cette épaisseur.  9. - Device according to claim 8, characterized in that the cover (26) extends, relative to the edge of the ring (258), on an axial height (H) greater than or equal to twice the axial thickness. (e27) bridges (27), preferably greater than or equal to three times this thickness, more preferably equal to four times this thickness.
10. - Dispositif selon l'une des revendications précédentes, caractérisé en ce que l'élément d'appui du couvercle (26) sur le bouchon (21 ) est constitué par un pion (262) s'étendant, le long de l'axe central du couvercle, en direction du bouchon, jusqu'au contact du bouchon.  10. - Device according to one of the preceding claims, characterized in that the support element of the cover (26) on the plug (21) is constituted by a pin (262) extending along the central axis of the lid, in the direction of the cap, until the cap is touched.
1 1 . - Dispositif selon la revendication 10, caractérisé en ce qu'en configuration montée du dispositif de bouchage (20) sur un récipient (1 ), l'élément d'appui (262) du couvercle (26) exerce sur le bouchon un effort de déformation élastique d'une partie centrale (214) du bouchon alignée sur le col (1 1 ) du récipient (1 ).  1 1. - Device according to claim 10, characterized in that in mounted configuration of the closure device (20) on a container (1), the support element (262) of the lid (26) exerts on the plug a force of elastic deformation of a central portion (214) of the plug aligned on the neck (1 1) of the container (1).
12. - Dispositif selon la revendication 1 1 , caractérisé en ce que, à la rupture des pontets, le bouchon (21 ) exerce sur l'élément d'appui (262) un effort élastique (E2) d'éjection du bouchon, cet effort élastique résultant de l'effort de déformation élastique de la partie centrale (214) du bouchon préalablement exercé par l'élément d'appui.  12. - Device according to claim 1 1, characterized in that, at the rupture of the bridges, the plug (21) exerts on the support element (262) an elastic force (E2) ejection of the plug, this elastic force resulting from the elastic deformation force of the central portion (214) of the cap previously exerted by the support element.
13. - Dispositif selon l'une des revendications précédentes, caractérisé en ce que le couvercle (26) est relié par la partie sécable (27) à une partie annulaire (254) de la bague qui est perpendiculaire à une jupe (251 ) de la bague, destinée à entourer le col (12) du récipient et équipée des moyens de verrouillage (253), en ce que la partie annulaire (254) est pourvue d'au moins une ouverture (255) et en ce que chaque ouverture est bordée, du côté du bouchon (21 ), par une nervure (259) destinée à pénétrer superficiellement le bouchon, radialement sur l'intérieur de l'ouverture. 13. - Device according to one of the preceding claims, characterized in that the cover (26) is connected by the breakable portion (27) to an annular portion (254) of the ring which is perpendicular to a skirt (251) of the ring, intended to surround the neck (12) of the container and equipped with locking means (253), in that the annular portion (254) is provided with at least one opening (255) and in that each opening is lined, on the side of the plug (21), by a rib (259) intended to penetrate superficially the plug, radially on the inside of the opening.
14.- Récipient (1 ), notamment flacon pour médicament, équipé d'un dispositif de bouchage (20) selon l'une des revendications précédentes.  14.- Container (1), especially medication bottle, equipped with a closure device (20) according to one of the preceding claims.
EP12729072.4A 2011-06-08 2012-06-07 Stopping device and container comprising such a device Active EP2718198B1 (en)

Priority Applications (1)

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FR1155015A FR2976265B1 (en) 2011-06-08 2011-06-08 CLOSURE DEVICE AND CONTAINER EQUIPPED WITH SUCH A DEVICE
PCT/EP2012/060788 WO2012168353A1 (en) 2011-06-08 2012-06-07 Stopping device and container comprising such a device

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EP2718198A1 true EP2718198A1 (en) 2014-04-16
EP2718198B1 EP2718198B1 (en) 2015-07-29

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EP (1) EP2718198B1 (en)
JP (2) JP6309890B2 (en)
CN (1) CN103687792B (en)
AU (1) AU2012266372B2 (en)
BR (1) BR112013031533A2 (en)
CA (1) CA2838127C (en)
ES (1) ES2546164T3 (en)
FR (1) FR2976265B1 (en)
PL (1) PL2718198T3 (en)
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JP2014518822A (en) 2014-08-07
CN103687792B (en) 2015-11-25
JP2018076125A (en) 2018-05-17
BR112013031533A2 (en) 2016-12-13
PL2718198T3 (en) 2016-01-29
JP6309890B2 (en) 2018-04-11
CN103687792A (en) 2014-03-26
RU2605173C2 (en) 2016-12-20
WO2012168353A1 (en) 2012-12-13
CA2838127C (en) 2019-01-08
FR2976265A1 (en) 2012-12-14
US20140209603A1 (en) 2014-07-31
FR2976265B1 (en) 2014-08-29
PT2718198E (en) 2015-10-02
CA2838127A1 (en) 2012-12-13
RU2013157372A (en) 2015-07-20
AU2012266372B2 (en) 2017-02-02
EP2718198B1 (en) 2015-07-29
AU2012266372A1 (en) 2014-01-16
ES2546164T3 (en) 2015-09-21
US9505533B2 (en) 2016-11-29

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