EP2715352A4 - Procédé d'évaluation du risque de lemp - Google Patents

Procédé d'évaluation du risque de lemp

Info

Publication number
EP2715352A4
EP2715352A4 EP12792375.3A EP12792375A EP2715352A4 EP 2715352 A4 EP2715352 A4 EP 2715352A4 EP 12792375 A EP12792375 A EP 12792375A EP 2715352 A4 EP2715352 A4 EP 2715352A4
Authority
EP
European Patent Office
Prior art keywords
pml
assessing risk
assessing
risk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP12792375.3A
Other languages
German (de)
English (en)
Other versions
EP2715352A2 (fr
EP2715352B1 (fr
Inventor
Meena Subramanyam
Tatiana Plavina
Gary Lewis Bloomgren
Carmen Bozic
Sophia Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen MA Inc
Original Assignee
Biogen MA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47260338&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP2715352(A4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to EP22209669.5A priority Critical patent/EP4187248A1/fr
Priority to DK19169482.7T priority patent/DK3575792T3/da
Priority to PL12792375T priority patent/PL2715352T3/pl
Priority to SI201231596T priority patent/SI2715352T1/sl
Application filed by Biogen MA Inc filed Critical Biogen MA Inc
Priority to RS20190690A priority patent/RS58967B1/sr
Priority to EP19169482.7A priority patent/EP3575792B1/fr
Publication of EP2715352A2 publication Critical patent/EP2715352A2/fr
Publication of EP2715352A4 publication Critical patent/EP2715352A4/fr
Publication of EP2715352B1 publication Critical patent/EP2715352B1/fr
Application granted granted Critical
Priority to HRP20190860TT priority patent/HRP20190860T1/hr
Revoked legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/22011Polyomaviridae, e.g. polyoma, SV40, JC
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01DNA viruses
    • G01N2333/025Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/20Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Exhaust Gas After Treatment (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
EP12792375.3A 2011-05-31 2012-05-31 Procédé d'évaluation du risque de lemp Revoked EP2715352B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
EP19169482.7A EP3575792B1 (fr) 2011-05-31 2012-05-31 Procédé d'évaluation du risque de lemp
DK19169482.7T DK3575792T3 (da) 2011-05-31 2012-05-31 Fremgangsmåde til vurdering af risiko for pml
PL12792375T PL2715352T3 (pl) 2011-05-31 2012-05-31 Metoda oceny ryzyka postępującej wieloogniskowej leukoencefalopatii (pml)
SI201231596T SI2715352T1 (sl) 2011-05-31 2012-05-31 Metoda ocenjevanja tveganja za nastanek PML
EP22209669.5A EP4187248A1 (fr) 2011-05-31 2012-05-31 Procédé d'évaluation du risque de lemp
RS20190690A RS58967B1 (sr) 2011-05-31 2012-05-31 Metod evaluacije rizika za pml
HRP20190860TT HRP20190860T1 (hr) 2011-05-31 2019-05-09 POSTUPAK PROCJENJIVANJA RIZIKA OD PML-a

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161491810P 2011-05-31 2011-05-31
US201161508584P 2011-07-15 2011-07-15
US201161550257P 2011-10-21 2011-10-21
US201261636588P 2012-04-20 2012-04-20
PCT/US2012/040283 WO2012166971A2 (fr) 2011-05-31 2012-05-31 Procédé d'évaluation du risque de lemp

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP19169482.7A Division EP3575792B1 (fr) 2011-05-31 2012-05-31 Procédé d'évaluation du risque de lemp
EP22209669.5A Division EP4187248A1 (fr) 2011-05-31 2012-05-31 Procédé d'évaluation du risque de lemp

Publications (3)

Publication Number Publication Date
EP2715352A2 EP2715352A2 (fr) 2014-04-09
EP2715352A4 true EP2715352A4 (fr) 2015-10-21
EP2715352B1 EP2715352B1 (fr) 2019-04-24

Family

ID=47260338

Family Applications (3)

Application Number Title Priority Date Filing Date
EP19169482.7A Active EP3575792B1 (fr) 2011-05-31 2012-05-31 Procédé d'évaluation du risque de lemp
EP12792375.3A Revoked EP2715352B1 (fr) 2011-05-31 2012-05-31 Procédé d'évaluation du risque de lemp
EP22209669.5A Pending EP4187248A1 (fr) 2011-05-31 2012-05-31 Procédé d'évaluation du risque de lemp

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP19169482.7A Active EP3575792B1 (fr) 2011-05-31 2012-05-31 Procédé d'évaluation du risque de lemp

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP22209669.5A Pending EP4187248A1 (fr) 2011-05-31 2012-05-31 Procédé d'évaluation du risque de lemp

Country Status (19)

Country Link
US (2) US12105090B2 (fr)
EP (3) EP3575792B1 (fr)
JP (5) JP6243838B2 (fr)
KR (3) KR102292563B1 (fr)
CN (1) CN103635803A (fr)
AU (1) AU2012262122B2 (fr)
CA (1) CA2836490A1 (fr)
CY (1) CY1121981T1 (fr)
DK (2) DK2715352T3 (fr)
ES (2) ES2729945T3 (fr)
FI (1) FI3575792T3 (fr)
HR (2) HRP20230186T1 (fr)
HU (2) HUE043339T2 (fr)
LT (2) LT2715352T (fr)
PL (2) PL3575792T3 (fr)
PT (2) PT2715352T (fr)
RS (2) RS63989B1 (fr)
SI (2) SI3575792T1 (fr)
WO (1) WO2012166971A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2676967T (lt) 2006-02-28 2019-09-10 Biogen Ma Inc. Uždegiminių ir autoimuninių ligų gydymo būdai su natalizumabu
ES2663377T3 (es) 2006-03-03 2018-04-12 Biogen Ma Inc. Métodos para el tratamiento de enfermedades inflamatorias y autoinmunes con natalizumab
AU2010303156B2 (en) 2009-10-11 2016-02-04 Biogen Ma Inc. Anti-VLA-4 related assays
BR112012017014B1 (pt) 2010-01-11 2021-07-20 Biogen Ma Inc Métodos para detecção de anticorpos de vírus jc
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
HUE043339T2 (hu) 2011-05-31 2019-08-28 Biogen Ma Inc Módszer a PML kockázatának megállapítására
WO2014193804A1 (fr) 2013-05-28 2014-12-04 Biogen Idec Ma Inc. Méthodes d'évaluation de risque de développement d'une lemp
US20160223565A1 (en) * 2013-09-18 2016-08-04 The Johns Hopkins University Bk virus serology assessment of progressive multifocal leukoencephalopathy (pml) risk
ES2818823T3 (es) * 2014-02-27 2021-04-14 Biogen Ma Inc Método de evaluación del riesgo de LMP
MA40985A (fr) 2014-11-17 2017-09-26 Biogen Ma Inc Méthodes de traitement de la sclérose en plaques
KR20200088350A (ko) 2017-10-26 2020-07-22 바이오젠 엠에이 인코포레이티드 나탈리주맙의 시간간격이 길어진 투약법
EP4243932A1 (fr) 2020-11-14 2023-09-20 Biogen MA Inc. Schémas posologiques sous-cutanés biphasiques pour des anticorps anti-vla-4
WO2022221458A1 (fr) 2021-04-13 2022-10-20 Biogen Ma Inc Compositions et méthodes de traitement de lésions chroniques actives de la matière blanche/syndrome radiologiquement isolé

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011085369A1 (fr) * 2010-01-11 2011-07-14 Biogen Idec Ma Inc. Essai d'anticorps anti-virus jc

Family Cites Families (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4235601A (en) 1979-01-12 1980-11-25 Thyroid Diagnostics, Inc. Test device and method for its use
US4391904A (en) 1979-12-26 1983-07-05 Syva Company Test strip kits in immunoassays and compositions therein
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4517288A (en) 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
US4703017C1 (en) 1984-02-14 2001-12-04 Becton Dickinson Co Solid phase assay with visual readout
NZ215865A (en) 1985-04-22 1988-10-28 Commw Serum Lab Commission Method of determining the active site of a receptor-binding analogue
CA1291031C (fr) 1985-12-23 1991-10-22 Nikolaas C.J. De Jaeger Methode pour la detection de liants specifiques et des substances liables par ceux-ci
US5763262A (en) 1986-09-18 1998-06-09 Quidel Corporation Immunodiagnostic device
DE291194T1 (de) 1987-04-27 1992-03-19 Unilever N.V., Rotterdam Immunoassays und vorrichtungen dafuer.
US4943522A (en) 1987-06-01 1990-07-24 Quidel Lateral flow, non-bibulous membrane assay protocols
US5120643A (en) 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
US4818677A (en) 1987-12-03 1989-04-04 Monoclonal Antibodies, Inc. Membrane assay using focused sample application
AU2684488A (en) 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US5221616A (en) 1988-07-15 1993-06-22 Quidel Corporation Prevention of spontaneous complement activation in mammalian biological fluids
US5118630A (en) 1988-11-04 1992-06-02 Quidel Corporation Method for determining periodic infertility in females
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
US6033665A (en) 1989-09-27 2000-03-07 Elan Pharmaceuticals, Inc. Compositions and methods for modulating leukocyte adhesion to brain endothelial cells
US5084828A (en) 1989-09-29 1992-01-28 Healthtech Services Corp. Interactive medication delivery system
US5252496A (en) 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
US5096837A (en) 1990-02-08 1992-03-17 Pacific Biotech, Inc. Immunochromatographic assay and method of using same
US5223220A (en) 1990-03-27 1993-06-29 Pacific Biotech, Inc. Solid phase immunoassay device and method of making same
US5118428A (en) 1990-11-13 1992-06-02 Quidel Method to remove red blood cells from whole blood samples
DE4139840B4 (de) 1990-12-04 2005-06-02 Quidel Corp., San Diego Antigen-Zubereitung zum Nachweis von H. pylori
EP0566695B1 (fr) 1991-01-11 1999-06-02 Quidel Corporation Methode de dosage en une seule phase a flux lateral et support non- spongieux utilise dedans
US5213796A (en) 1991-05-06 1993-05-25 Dana Farber Cancer Institute Assay for polyomavirus in humans and uses thereof
US5225328A (en) 1991-05-30 1993-07-06 Quidel Corporation Stable alkaline phosphatase compositions with color enhancement and their use in assays
US5686315A (en) 1991-06-14 1997-11-11 Quidel Corporation Assay device for one step detection of analyte
EP0646179A4 (fr) 1992-02-04 1996-10-02 Quidel Corp Procede d'extraction simplifie d'antigenes bacteriens au moyen de reactifs deshydrates.
US5541069A (en) 1992-02-28 1996-07-30 Quidel Corporation Assay having improved dose response curve
JP2948318B2 (ja) 1992-03-10 1999-09-13 クイデル コーポレイション 特異的結合アッセイ用の赤血球の分離方法
DK0678122T3 (da) 1993-01-12 2000-03-06 Biogen Inc Rekombinante anti-VLA4 antistofmolekyler
US5415994A (en) 1993-08-02 1995-05-16 Quidel Corporation Lateral flow medical diagnostic assay device with sample extraction means
US5840299A (en) 1994-01-25 1998-11-24 Athena Neurosciences, Inc. Humanized antibodies against leukocyte adhesion molecule VLA-4
US5434057A (en) 1994-02-02 1995-07-18 Quidel Corporation Sperm motility assay and devices
US5521102A (en) 1994-08-08 1996-05-28 Quidel Corporation Controlled sensitivity immunochromatographic assay
US5845255A (en) 1994-10-28 1998-12-01 Advanced Health Med-E-Systems Corporation Prescription management system
US6551593B1 (en) 1995-02-10 2003-04-22 Millennium Pharmaceuticals, Inc. Treatment of Inflammatory bowel disease by inhibiting binding and/or signalling through α 4 β 7 and its ligands and madcam
US5712172A (en) 1995-05-18 1998-01-27 Wyntek Diagnostics, Inc. One step immunochromatographic device and method of use
US5804452A (en) 1995-04-27 1998-09-08 Quidel Corporation One step urine creatinine assays
US5786220A (en) 1995-04-28 1998-07-28 Quidel Corporation Assays and devices for distinguishing between normal and abnormal pregnancy
US20010051350A1 (en) 1995-05-02 2001-12-13 Albert Nazareth Diagnostic detection device and method
US5773234A (en) 1995-08-07 1998-06-30 Quidel Corporation Method and device for chlamydia detection
DE19543553B4 (de) 1995-11-22 2009-04-09 Deutsches Primatenzentrum Gmbh VP-Antigene des JC-Virus
CN103275221B (zh) 1996-02-09 2016-08-17 艾伯维生物技术有限公司 结合人TNFα的人抗体
US6305377B1 (en) 1996-12-12 2001-10-23 Michael T. Portwood System and method for improving compliance of a medical regimen
US6229011B1 (en) 1997-08-22 2001-05-08 Hoffman-La Roche Inc. N-aroylphenylalanine derivative VCAM-1 inhibitors
US6306642B1 (en) 1997-11-24 2001-10-23 Quidel Corporation Enzyme substrate delivery and product registration in one step enzyme immunoassays
US6623981B2 (en) 1998-01-27 2003-09-23 Bristol-Myers Squibb Company Detection of patients at risk for developing integrin antagonist/agonist mediated disease states
US6014631A (en) 1998-04-02 2000-01-11 Merck-Medco Managed Care, Llc Computer implemented patient medication review system and process for the managed care, health care and/or pharmacy industry
US6045501A (en) 1998-08-28 2000-04-04 Celgene Corporation Methods for delivering a drug to a patient while preventing the exposure of a foetus or other contraindicated individual to the drug
US6407066B1 (en) 1999-01-26 2002-06-18 Elan Pharmaceuticals, Inc. Pyroglutamic acid derivatives and related compounds which inhibit leukocyte adhesion mediated by VLA-4
US7171371B2 (en) 1999-09-03 2007-01-30 Smg Trust Method and system for providing pre and post operative support and care
AU7787100A (en) 1999-10-12 2001-04-23 Connex Gesellschaft Zur Optimierung Von Forschung Und Entwicklung Mbh Improved method for the detection of acid resistant microorganisms in a stool
US6388084B1 (en) 1999-12-06 2002-05-14 Hoffmann-La Roche Inc. 4-pyridinyl-n-acyl-l-phenylalanines
DE60043308D1 (de) 1999-12-16 2009-12-24 Biogen Idec Inc Verfahren zur behandlung der schädigung des zentralnervensystems durch ischämie oder durch hämorrhagie mit antagonisten von alpha4 integrin
AU2001233034A1 (en) 2000-01-27 2001-08-07 American Cyanamid Company Method for preparing alpha-sulfonyl hydroxamic acid derivatives
AU4465001A (en) 2000-03-30 2001-10-15 Nippon Kayaku Kabushiki Kaisha Method of examining cancer by assaying autoantibody against mdm2 and reagent therefor
US6620626B1 (en) 2000-08-09 2003-09-16 Mission Research Corp. Antigen detection device and method
MY129000A (en) 2000-08-31 2007-03-30 Tanabe Seiyaku Co INHIBITORS OF a4 MEDIATED CELL ADHESION
ATE403153T1 (de) 2000-10-17 2008-08-15 Besst Test Aps Test zum direkten nachweisen einer rs virus bezogenen biologischen zelle in einer körperflüssigkeitsprobe
US6315720B1 (en) 2000-10-23 2001-11-13 Celgene Corporation Methods for delivering a drug to a patient while avoiding the occurrence of an adverse side effect known or suspected of being caused by the drug
US6485460B2 (en) 2001-01-12 2002-11-26 Bracco Diagnostics, Inc. Tamper evident syringe barrel
AU2002331408B2 (en) 2001-08-20 2008-05-08 Proteome Systems Ltd Diagnostic testing process and apparatus
WO2003016902A1 (fr) 2001-08-20 2003-02-27 Proteome Systems Intellectual Property Pty Ltd Procede et appareil d'epreuve diagnostique
US6605602B1 (en) 2001-09-28 2003-08-12 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Method of treating BK virus nephropathy
CA2478547C (fr) * 2001-12-03 2011-09-20 Abgenix, Inc. Identification de molecules de haute affinite par depistage par dilutions limitees
IL163725A0 (en) 2002-02-25 2005-12-18 Elan Pharm Inc Administration of agents for the treatment of inflammation
TW200307671A (en) 2002-05-24 2003-12-16 Elan Pharm Inc Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins
TWI281470B (en) 2002-05-24 2007-05-21 Elan Pharm Inc Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins
WO2004001539A2 (fr) 2002-06-21 2003-12-31 Mckesson Information Solutions Llc Systeme et procede de consommation de medicaments en boucle fermee
US20070275481A1 (en) 2003-11-24 2007-11-29 Biogen Idec Ma Inc. Methods For Detecting Half-Antibodies Using Chip Based Gel Electophoresis
JP4672263B2 (ja) 2004-01-27 2011-04-20 デンカ生研株式会社 簡便な検出法、検出装置及び検出キットとその製法
US7419666B1 (en) 2004-02-23 2008-09-02 Massachusetts Eye And Ear Infirmary Treatment of ocular disorders
TWI439284B (zh) 2004-04-09 2014-06-01 Abbvie Biotechnology Ltd 用於治療TNFα相關失調症之多重可變劑量療法
US20050283385A1 (en) 2004-06-21 2005-12-22 The Permanente Medical Group, Inc. Individualized healthcare management system
NZ588839A (en) 2004-07-08 2012-09-28 Elan Pharm Inc Multivalent vla-4 antagonists comprising polyethylene glycol moieties
CA2478458A1 (fr) 2004-08-20 2006-02-20 Michael Panzara Traitement de la sclerose en plaques pediatrique
EP1833509A4 (fr) 2004-12-03 2008-12-03 Biogen Idec Inc Retardement ou prevention de l'apparition d'une sclerose en plaques
EP1863940B1 (fr) 2005-03-03 2012-06-06 Seedlings Life Science Ventures, LLC. Méthode de gestion des risques concernant les patients soumis à un traitement à base de natalizumab
SI2645106T1 (en) 2005-04-04 2018-01-31 Biogen Ma Inc. METHODS FOR EVALUATION OF THE IMMUNE RESPONSE TO THERAPEUTIC MEDICINE
CA2614737A1 (fr) * 2005-07-08 2007-01-18 Philadelphia Health & Education Corporation D/B/A Drexel University Coll Ege Of Medicine Methodes permettant de controler la destruction des neurones par neuroinflammation et de traiter des maladies presentant une composante inflammatoire liee a la phospholipase a2
NZ567270A (en) 2005-09-29 2011-06-30 Elan Pharm Inc Pyrimidinyl amide compounds which inhibit leukocyte adhesion mediated by VLA-4
EA017110B1 (ru) 2006-02-27 2012-09-28 Элан Фамэсьютикэлс, Инк. ПИРИМИДИНИЛСУЛЬФОНАМИДНЫЕ СОЕДИНЕНИЯ (ВАРИАНТЫ), СПОСОБ ПОЛУЧЕНИЯ ПИРИМИДИНИЛСУЛЬФОНАМИДНЫХ СОЕДИНЕНИЙ (ВАРИАНТЫ), ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ, ОПОСРЕДОВАННОГО ИНТЕГРИНОМ α4, СПОСОБ СНИЖЕНИЯ И/ИЛИ ПРЕДУПРЕЖДЕНИЯ ВОСПАЛИТЕЛЬНОГО КОМПОНЕНТА ЗАБОЛЕВАНИЯ ИЛИ АУТОИММУННОГО ОТВЕТА
LT2676967T (lt) 2006-02-28 2019-09-10 Biogen Ma Inc. Uždegiminių ir autoimuninių ligų gydymo būdai su natalizumabu
US8410115B2 (en) 2006-02-28 2013-04-02 Elan Pharmaceuticals, Inc. Methods of treating inflammatory and autoimmune diseases with alpha-4 inhibitory compounds
ES2663377T3 (es) 2006-03-03 2018-04-12 Biogen Ma Inc. Métodos para el tratamiento de enfermedades inflamatorias y autoinmunes con natalizumab
WO2008021954A2 (fr) * 2006-08-09 2008-02-21 Biogen Idec Ma Inc. Procédé de distribution d'un médicament
TWI415845B (zh) * 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與5-ht2a血清素受體相關聯病症之作為5-ht2a血清素受體之調節劑的吡唑衍生物
US20080233150A1 (en) 2006-11-16 2008-09-25 Gale Smith Respiratory syncytial virus-virus like particle (vlps)
EP1933140B1 (fr) 2006-12-11 2011-08-17 AraGen Biotechnology Co. Ltd. Procédé pour la détection des anticorps par un signal d'or colloïdal amplifié par des oligonucléotides
TW200846363A (en) * 2007-03-22 2008-12-01 Urrma R & B Novel human anti-R7V antibodies and uses thereof
FR2919804B1 (fr) * 2007-08-08 2010-08-27 Erytech Pharma Composition et vaccin therapeutique anti-tumoral
EP4335932A3 (fr) * 2008-11-07 2024-06-26 Adaptive Biotechnologies Corporation Procédés de surveillance de conditions par analyse de séquence
EP2394163B1 (fr) 2009-02-05 2020-08-19 Biogen MA Inc. Procédés pour détecter le polyomavirus jc
WO2010096674A2 (fr) 2009-02-20 2010-08-26 The Regents Of The University Of California Dosages de biomarqueur a+
HUE043339T2 (hu) 2011-05-31 2019-08-28 Biogen Ma Inc Módszer a PML kockázatának megállapítására
WO2014193804A1 (fr) * 2013-05-28 2014-12-04 Biogen Idec Ma Inc. Méthodes d'évaluation de risque de développement d'une lemp

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011085369A1 (fr) * 2010-01-11 2011-07-14 Biogen Idec Ma Inc. Essai d'anticorps anti-virus jc

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
LEONID GORELIK ET AL: "Anti-JC virus antibodies: Implications for PML Risk Stratification", ANNALS OF NEUROLOGY, vol. 68, no. 3, 24 August 2010 (2010-08-24), pages 295 - 303, XP055136721, ISSN: 0364-5134, DOI: 10.1002/ana.22128 *
PLAVINA T ET AL: "Anti-JCV antibody index further defines PML risk in natalizumab-treated MS patients The 27th Annual Meeting of the Consortium of Multiple Sclerosis Centers ACKNOWLEDGMENTS", ACCESSED MARCH NEUROLOGY. NEUROLOGY. WARNKE C J NEUROL NEUROSURG PSYCHIATRY ANN NEUROL, 30 May 2013 (2013-05-30), pages 1736 - 1742742, XP055190187, Retrieved from the Internet <URL:https://cmscactrims.confex.com/cmscactrims/2013/webprogram/Handout/Paper1642/Plavina_Tysabri JCV Ab Index_2013 CMSC Poster_FINAL.pdf> [retrieved on 20150519] *
SANDROCK ALFRED ET AL: "Risk Stratification for Progressive Multifocal Leukoencephalopathy (PML) in MS Patients: Role of Prior Immunosuppressant Use, Natalizumab-Treatment Duration, and Anti-JCV Antibody Status", NEUROLOGY, vol. 76, no. 9, Suppl. 4, March 2011 (2011-03-01), & 63RD ANNUAL MEETING OF THE AMERICAN-ACADEMY-OF-NEUROLOGY; HONOLULU, HI, USA; APRIL 09 -16, 2011, pages A248, XP055189963, ISSN: 0028-3878 *
SUBRAMANYAM MEENA ET AL: "Anti-JCV Antibodies Are Consistently Detected Prior to and after PML Diagnosis in Natalizumab-Treated MS Patients", NEUROLOGY, vol. 76, no. 9, Suppl. 4, March 2011 (2011-03-01), & 63RD ANNUAL MEETING OF THE AMERICAN-ACADEMY-OF-NEUROLOGY; HONOLULU, HI, USA; APRIL 09 -16, 2011, pages A636 - A637, XP008176353, ISSN: 0028-3878 *
WARNKE CLEMENS ET AL: "Natalizumab and progressive multifocal leukoencephalopathy: what are the causal factors and can it be avoided?", ARCHIVES OF NEUROLOGY,, vol. 67, no. 8, 1 August 2010 (2010-08-01), pages 923 - 930, XP009146630, DOI: 10.1001/ARCHNEUROL.2010.161 *

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