EP2033706B1 - Appareil d'émulsification - Google Patents

Appareil d'émulsification Download PDF

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Publication number
EP2033706B1
EP2033706B1 EP08014632A EP08014632A EP2033706B1 EP 2033706 B1 EP2033706 B1 EP 2033706B1 EP 08014632 A EP08014632 A EP 08014632A EP 08014632 A EP08014632 A EP 08014632A EP 2033706 B1 EP2033706 B1 EP 2033706B1
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EP
European Patent Office
Prior art keywords
flow channel
phase inlet
sheath
continuous phase
dispersion phase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP08014632A
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German (de)
English (en)
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EP2033706A3 (fr
EP2033706A2 (fr
Inventor
Mio Suzuki
Shigenori Togashi
Tetsuro Miyamoto
Yoshishige Endo
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Hitachi Plant Technologies Ltd
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Hitachi Plant Technologies Ltd
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Publication date
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Publication of EP2033706A2 publication Critical patent/EP2033706A2/fr
Publication of EP2033706A3 publication Critical patent/EP2033706A3/fr
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Publication of EP2033706B1 publication Critical patent/EP2033706B1/fr
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4335—Mixers with a converging-diverging cross-section
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B01F33/3011—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/81—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/81—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
    • B01F33/813—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles mixing simultaneously in two or more mixing receptacles

Definitions

  • the present invention relates to an emulsification apparatus.
  • emulsion is formed, in either an O/W type, wherein an oil (which may be called a dispersion phase) is dispersed within water (which may be called a continuous phase), by applying a shearing force upon two liquids, which are insoluble with each other, such as, water and oil, or a W/O type, wherein water (which may be called the dispersion phase) is dispersed within oil (which may be called, the continuous phase).
  • an oil which may be called a dispersion phase
  • water which may be called the continuous phase
  • Patent Document 1 there is disclosed a method utilizing the liquid shearing velocity, which is generated between the wall surface of a flow path or channel by squeezing the flow channel, in a step-wise manner, while dividing oil and water into a large number of flows, to arrange them one another, thereby increasing a contact area between those liquids.
  • Patent Document 2 there is described a method for obtaining an emulsion by a cavitations-drop function due to repetition of collisions upon the wall surfaces of separation flow channels and pressure drop within the apparatus, while letting flow a mixture of two liquids to be emulsified, which are mixed in advance, into that apparatus.
  • Non-Patent Document 1 a method for obtaining emulsion through separation of the dispersion phase therefrom, which flows inside a sheath flow, while forming that sheath flow by forming the dispersion phase in the inside and forming the continuous phase at the outside thereof.
  • Patent Documents 1 and 2 With the emulsifying methods described in Patent Documents 1 and 2, it is possible to obtain an improvement on the distribution of particle diameters of the emulsion, compared to the batch method; however, there is brought about a certain degree of an extent. Also, there remains a problem that it is difficult to produce an emulsion having relatively large particle diameters. And, also with the method described in Patent Document 2, it is necessary to provide a mechanism, separately, for keeping two liquids to be mixed, which should be emulsified.
  • the apparatus described in the Non-Patent Document 1 it is possible to arrange the particle diameters to be equal, and also to obtain emulsion particles having a relatively large particle diameter; however, with this method, the throughput flow of liquid is small, such as about 1 mL/min, for example, and therefore it is essential to provide flow channels in parallel, in order to increase the throughput flow thereof.
  • Non-Patent Document 1 With the apparatus described in Non-Patent Document 1, all flow paths or channels are formed on a laminated surface of materials being piled up, including introduction flow channels and combining flow channels of two kinds of liquids, a flow channel for forming the sheath flow, and a flow channel where the sheath flow is divided so as to produce particles. For this reason, since the direction is restricted only to one direction, into which the parallel channels can be obtained without changing the number of pieces of the laminated plate-like materials, and therefore it is impossible to increase the throughput flow, in an effective manner.
  • the flow channels within the apparatus described in the Non-Patent Document 1, are formed by laminating the structure after forming grooves by photolithography thereon, there is a necessity of conducting complicated processes for forming the flow channel itself.
  • the flow channels for forming that sheath flow channel and other flow channels are on the same material member, and therefore, for adjusting the particle diameter, by changing the flow channel widths of the sheath flow channels, it is necessary to remake the flow channels as a whole.
  • EP 1 930 070 Al discloses an emulsifying apparatus suitable for conducting an emulsion by mixing two kinds of liquids, being immiscible with each other, having a plural number of laminated portions, comprising: a dispersion phase inlet flow channel, which is formed on one of said plural number of laminated portions in a direction perpendicular to the plane of lamination; a sheath flow channel, which is connected via a continuous phase inlet flow channel which is formed in at least one of said two laminated portions, in the lamination plane thereof, so as to create a connection portion of said dispersion phase inlet flow channel and said sheath flow channel on a same axis to said dispersion phase inlet flow channel and is formed in a direction perpendicular to the lamination plane of two of said portions.
  • Fig. 1 is the structural view of a system including an emulsifying apparatus, according to one embodiment of the present invention.
  • an O/W emulsion is produced by using water, including a surface active agent therein, as a continuous phase, while using an oil as the dispersion phase.
  • Fig. 1 in raw material tanks 101A and 101B are reserved or retained water and oil, respectively. From those raw material tanks 101A and 101B, liquids are transferred by means of pumps 102A and 102B, respectively. As those pumps 102A and 102B, it is preferable to apply a syringe pump or a gear pump, etc., separately, depending on the purpose thereof.
  • the liquids transferred by the pumps 102A and 102B flow into an emulsifying apparatus 104 through introductory tubes 103A and 103B, respectively, and within this an emulsifying apparatus 104 is produced an emulsion thereof.
  • the produced emulsion is stored within an emulsion tank 106 into which it is delivered through a deliver tube 105.
  • a temperature adjustment is necessary upon producing the emulsion, it is also possible to adopt a method of conducting the temperature adjustment, by filling up a thermostatic chamber 107 with a heating medium, while providing the emulsifying apparatus 104 within that thermostatic chamber 107, for example.
  • a Peltier device or the like may be provided on the outside of the emulsifying apparatus 104.
  • Fig. 2 is an exploded perspective view for showing the structures of the emulsifying apparatus 104, seen from the side of the introductory portion of the continuous phase and the dispersion phase.
  • Fig. 3 is a perspective view for showing the above, but seen from the side of the emulsion deliver portion.
  • Fig. 4 is a perspective view for showing a combining flow channel portion 202 shown in Figs. 2 and 3 , seen from the side of the emulsion deliver portion.
  • Fig. 5 is a cross-sectional view of the emulsifying apparatus shown in Figs. 2 and 3 , combined with other members, in particular, along with the A-A cutting line shown in Fig. 2 .
  • Fig. 6 is an enlarged view of a portion within the circle referenced by "B" in Fig. 5 .
  • the emulsifying apparatus 104 shown in Fig. 1 comprises as is shown in Figs. 2 , 3 and 5 , a liquid introductory portion 201, a combining flow channel portion 202, a sheath flow channel portion 203, an enlarged flow channel portion 204, and a liquid delivery or outlet portion 205, wherein those are jointed or fastened to one another by using screws (not shown in the figure) penetrating screw holes 206.
  • On each of the members to be jointed is formed a sealing groove 207, so as to put a sealing member (not shown in the figure) therebetween, thereby to prevent the liquid from leaking therethrough. Or, depending on necessity thereof, it is possible to use them after adhering or bonding between those members.
  • a material of the members building up the emulsifying apparatus 104 is used a metal or a resin, or a glass, etc., depending upon the sorts of liquids to be transferred therein. Also, there is no necessity that the materials of all the members are same, but they may be changed for each of the members, for example, depending on the characteristics in processing thereof, the thermal conductivity thereof, etc.
  • the water which presents the continuous phase and the oil which presents the dispersion phase are introduced from a continuous phase introductory opening 208 and a dispersion phase introductory opening 209, respectively, into a liquid introductory portion 201.
  • introductory tubes 103A and 103B which are shown in Fig. 1 , by using a coupling (not shown in the figure), and the liquids are transferred into the emulsifying apparatus 104 by means of the pumps 102A and 102B.
  • the water distributed herein is introduced into a continuous phase inlet flow channel 302 (shown in Figs. 3 and 4 ), which is formed on the same plane as the continuous phase dividing flow channel 301 and is symmetric with respect to an axis of a dispersion phase inlet flow channel 211, seen from the outside thereof.
  • the oil introduced from the dispersion phase introductory opening 209 shown in Fig.
  • the dispersion phase (i.e., the oil) flows into the dispersion phase inlet flow channel 211, which is provided in the combining flow channel portion 202.
  • the continuous phase inlet flow channel 302 in which the continuous phase (i.e., the water) flows. At this intersecting portion, the oil and the water are combined with each other.
  • this sheath flow flows into an enlarged flow channel 213, which is formed on the same axis as the sheath flow channel 212 and in a direction perpendicular to the surface of the laminated layers of the member within the enlarged flow channel portion 204 that is located downstream of the sheath flow portion 203, wherein an emulsion of O/W is produced.
  • the O/W emulsion produced is taken out from there, via an emulsion deliver flow channel 214, from an emulsion deliver opening 304.
  • channel width of the sheath flow channel 212 is finest and that channel widths of others are wider than that of the sheath flow channel 212.
  • the continuous phase dividing flow channel 301 for delivering the water into the continuous phase inlet flow channel 302 it is desirable to make such design that, the pressure loss generated within the continuous phase inlet flow channel 302 is dominant, by bringing the channel width of the continuous phase dividing flow channel 301 to be sufficiently wide with respect to the channel width of the continuous phase inlet flow channel 302, so as to distribute the water to a plural number of the continuous phase inlet flow channels 302, equally or uniformly.
  • each flow channel should not be limited to the configuration shown in the present embodiment, but for example, the cross-sectional configuration of the continuous phase introductory flow channel 210, the sheath flow channel 212 or the enlarged flow channel 213 may be a rectangular. However, for the purpose of forming a stable sheath flow and obtaining a uniform emulsion particle, it is desirable that the cross-sectional configuration of the sheath flow channel 212 and the enlarged flow channel 213 are symmetric to the axis of the flow channel.
  • Figs. 3 and 4 show two continuous phase inlet channels 302 which are symmetric to the axis of the dispersion phase inlet flow channel 211, with respect to the dispersion phase inlet flow channel 211 formed within the combining flow channel portion 202, but for this continuous phase inlet channel 302, it is not necessary to be as shown in Figs. 3 and 4 , as to the number of dispositions and the detailed configuration thereof, as far as it satisfies the axially symmetrical disposition with respect to the axis of the dispersion phase inlet flow channel 211.
  • Figs. 7(a) and 7(b) show perspective views of the continuous phase inlet flow channels, differing from each other in the configuration thereof.
  • Figs. 7(a) shows a configuration of providing four sets of the continuous phase inlet flow channels 302 for the dispersion phase inlet flow channel 211, thereby letting the continuous phase flow in from four directions.
  • Fig. 7(b) eight sets of continuous phase inlet flow channels 302 are built up, and the eight sets of flow channels are combined on the way thereof. Therefore, it is the configuration of combining the continuous phase directing into the dispersion phase flow channel 211 at a center from all directions on a plane.
  • the continuous phase inlet flow channels 302 are disposed to be symmetric to the axis of the dispersion phase inlet flow channel 211, i.e., the continuous phase is distributed by the continuous phase dividing flow channel 301, which is formed on the same plane, in the structures thereof.
  • Fig. 8 is an enlarged cross-sectional view showing the sheath flow channel, diagrammatically.
  • the oil discharged from the dispersion phase inlet flow channel 211 is combined with the water running from outside within the continuous phase flow channels 302, and thereby forming a sheath flow 801 residing the oil inside.
  • This sheath flow 801 residing the oil inside is divided during it flows within the sheath flow channel 212 and the enlarged flow channel 213 downstream thereof, and thereby forming emulsion particles 802.
  • the emulsion particles 802 grow up in particle diameter , accompanied with an increase of width occupied within the channel of the oil, in the sheath flow 801 residing the oil inside. Accordingly, as a method for controlling the particle diameter of the emulsion particles 802, it can be considered to increase or decrease the width occupied by the oil within the flow channel, in particular, within the sheath flow 801, by changing the flow rate between the water and the oil, which are introduced from the continuous phase inlet opening 208 and the dispersion phase inlet opening 209, respectively, or by changing the channel width of the sheath flow channel 212.
  • the sheath flow channel portion 203 having the sheath flow channel 212 therein is built up with a member depending on other members, when wishing to change the particle diameter of the emulsion particle 802, it is possible to deal with only by exchanging the sheath flow channel portion 203 depending on the particle diameter desired, while producing several kinds of sheath flow channel portions 203, each differing from in an inner diameter of the sheath flow channel 212 thereof.
  • Fig. 9 is an exploded perspective view of another embodiment of the emulsifying apparatus according to the present invention.
  • Fig. 10 is a perspective view of the emulsifying apparatus shown in Fig. 9 , seen from the side of the emulsion outlet portion.
  • Fig. 11 is a perspective view of the combining flow channel portion, when seen from the side of the emulsion outlet portion.
  • Fig. 12 is an enlarged perspective view of the "C" portion indicated by a broken line in Fig. 11 .
  • the emulsifying apparatus 104 comprises as is shown in Figs. 9 and 10 , the liquid introductory portion 201, the combining flow channel portion 202, the sheath flow channel portion 203, the enlarged flow channel portion 204, and the liquid delivery or outlet portion 205, wherein those are jointed or fastened to one another by using screws (not shown in the figure) penetrating the screw holes 206.
  • On each of the members is formed a sealing groove 207, so as to put a sealing member (not shown in the figure) therebetween, thereby to prevent the liquid from leaking therethrough. Or, depending on necessity thereof, it is possible to use them after adhering or bonding between those members.
  • a material of the members building up the emulsifying apparatus 104 is used a metal or a resin, or a glass, etc., depending upon the sorts of liquids to be transferred therein. Also, there is no necessity that the materials of all the members are same, but they may be changed for each of the members, for example, depending on the characteristics in processing thereof, the thermal conductivity thereof, etc.
  • the water to be the continuous phase and the oil to be the dispersion phase are introduced from a continuous phase introductory opening 208 and a dispersion phase introductory opening 209, respectively, into a liquid introductory portion 201.
  • a continuous phase introductory opening 208 and a dispersion phase introductory opening 209 is connected to the continuous phase introductory opening 208 and the dispersion phase introductory opening 209 to the continuous phase introductory opening 208 and the dispersion phase introductory opening 209 is connected the introductory tubes 103, which are shown in Fig. 1 , by using a coupling (not shown in the figure), and the liquids are transferred into the emulsifying apparatus 104 by means of the pumps 102.
  • the continuous phase inlet flow channels 302 On the plane forming this continuous phase dividing flow channel 301 thereon are disposed the continuous phase inlet flow channels 302 in plural numbers thereof, and herein, the water, i.e., the continuous phase, is divided to flow into the continuous phase inlet flow channels 302.
  • the oil introduced from the dispersion phase introductory opening 209 passes through the dispersion phase introductory flow channel 303. Thereafter, it is distributed through a dispersion phase dividing flow channel 1001, which is formed on the lamination plane of the liquid the liquid introductory portion 201, and passes through the dispersion phase inlet flow channels 211, being formed in plural number thereof, to be perpendicular to the lamination plane, within the combining flow channel portion 202. Thereafter, it flows into a combining portion of the continuous phase inlet flow channel 302, which is disposed to be axially symmetric to the axis of the dispersion phase inlet flow channels 211.
  • each of the continuous phase inlet flow channels 302 and the dispersion phase inlet flow channels 211 run into the sheath flow channels 212 formed in plural numbers thereof, each being on the same axis to the dispersion phase inlet flow channel 211 and perpendicular to the lamination plane of the member, within the sheath flow channel portion 203.
  • the water and the oil running therein form a sheath flow residing the water in the inside while residing the oil at the outside thereof.
  • this sheath flow runs into enlarged flow channels 213 formed in plural numbers thereof, each being on the same axis to the sheath flow channel 212 and perpendicular to the lamination plane of the member, within the enlarged flow channel portion 204 located downstream of the sheath flow channel portion 203, and thereby producing the O/W emulsion.
  • the O/W emulsion produced is collected by means of an emulsion combining flow channel 901, which is formed on the lamination plane of the liquid delivery or outlet portion 205 locating downstream thereof, and it is taken out from the emulsion deliver opening 304, via the emulsion delivery flow channel 214.
  • the channel width of the sheath flow channel 212 is finest and that the channel widths of others are wider than that of the sheath flow channel 212.
  • the continuous phase dividing flow channels 301 for delivering the water into the plural numbers of continuous phase inlet flow channels 302, and also dispersion phase dividing flow channels 1001 for distributing the oil to the plural number of dispersion phase discharge openings it is necessary to distribute the water or the oil, equally or uniformly. For that reason, it is desirable to make such design that, the pressure losses generated within the continuous phase inlet flow channel 302 and the dispersion phase inlet flow channel 211 are dominant, by making the channel width of the continuous phase dividing flow channel 301 and the dispersion phase dividing flow channel 1001 sufficiently wide with respect to the channel widths of the continuous phase inlet flow channel 302 and the dispersion phase inlet flow channel 211.
  • each flow channel should not be limited to the configuration shown in the present embodiment, but for example, the cross-section configuration of the continuous phase introductory flow channel 210, the sheath flow channel 212 or the enlarged flow channel 213 may be rectangular. However, for the purpose of forming a stable sheath flow and obtaining uniform emulsion particles, it is desirable that the cross-section configuration of the sheath flow channel 212 and the enlarged flow channel 213 are symmetric to the axis of the flow channel. Also, in Figs.
  • this continuous phase flow channel 302 needs not always to have such configuration as shown in each of the figures; for example, it may be in such a configuration that four pieces of continuous phase inlet flow channels 302 are disposed to be axially symmetric with, to the axis of the dispersion phase inlet flow channel 211.
  • the present invention should not be restricted to that detailed configuration, as far as satisfying the disposition of being axially symmetric with, to the axis of the dispersion phase inlet flow channel 211.
  • the present invention in other words, is limited in increasing the number of the dispersion phase inlet flow channels and the continuous phase inlet flow channels, for increasing the throughput of emulsion processing, in particular, in case where the dispersion phase inlet flow channels and the continuous phase inlet flow channels are on the same plane, as was described in the Non-Patent Document.
  • the dispersion phase inlet flow channel is extended in the direction of the surface on the drawing paper, the emulsifying apparatus as a whole becomes large in the size if aligning the dispersion phase inlet flow channels and the continuous phase inlet flow channels in plural numbers thereof in parallel with.
  • the present invention it is possible to dispose the plural numbers of the dispersion phase inlet flow channels and the continuous phase inlet flow channels, by taking only the number of the continuous phase inlet flow channels into the consideration, and therefore it is possible to increase the throughput of producing the emulsion for that reason.
  • the sheath flow which is formed by two kinds of liquids, each being indissoluble in each other, can be formed in the direction of lamination of the members, then it is possible to produce the emulsion having a uniform particle diameter and also a large particle diameter to a certain extent, through the sheath flow method.
  • the processes necessary for each member is only a process of drilling, or a simple process of gutter machining, and therefore, it is possible to build up the plural number of sheath flow channels with only a simple process, such as, a mechanical machining.
  • the flow channels for forming the sheath flow and flow channels for other than that can be disassembled from each other, and it is possible to achieve the control upon the particle diameter of the emulsion particles, by changing the channel width of the sheath flow channel, through replacement of only the member, which has the combining flow channel, with a member, which has the combining flow channel of a different channel width.

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Colloid Chemistry (AREA)

Claims (5)

  1. Appareil d'émulsification (104) adapté pour réaliser une émulsion en mélangeant deux sortes de liquides, non miscibles l'un avec l'autre, incluant une pluralité de parties stratifiées (201-205), comprenant :
    un canal d'écoulement d'admission de phase de dispersion (211), qui est formé sur l'une (202) desdites parties stratifiées (201-205) dans une direction perpendiculaire au plan de stratification ;
    un canal d'écoulement en gaine (212), qui est relié, par l'intermédiaire d'un canal d'écoulement d'admission de phase continue (302) qui est formé dans au moins l'une (202) des deux dites parties stratifiées (201-205), dans le plan de stratification de celles-ci, afin de créer une partie de liaison dudit canal d'écoulement d'admission de phase de dispersion (211) et dudit canal d'écoulement en gaine (212) sur un même axe, audit canal d'écoulement d'admission de phase de dispersion (211) et qui est formé dans une direction perpendiculaire au plan de stratification de deux desdites parties (201, 202) ; caractérisé en ce qu'un canal d'écoulement de mélange agrandi (213), présentant une largeur supérieure à celle dudit canal d'écoulement en gaine (212), est disposé en aval dudit canal d'écoulement en gaine (212), et ledit canal d'écoulement d'admission de phase de dispersion (211), ledit canal d'écoulement en gaine (212) et ledit canal d'écoulement de mélange agrandi (213) sont disposés de manière à se trouver sur le même axe,
    dans lequel ledit canal d'écoulement d'admission de phase de dispersion (211), ledit canal d'écoulement d'admission de phase continue (302), ledit canal d'écoulement en gaine (212) et ledit canal d'écoulement de mélange agrandi (213) sont disposés en plusieurs exemplaires à l'intérieur des éléments stratifiés (202, 203, 204) qui les constituent,
    et dans lequel un canal d'écoulement en gaine (212), permettant de combiner les liquides s'écoulant à travers ladite pluralité de canaux d'écoulement en gaine (212) ou ledit canal d'écoulement de mélange agrandi (213), est formé dans un plan de stratification de ladite partie (203), sur laquelle est formé ledit canal d'écoulement d'admission de phase de dispersion (211), ou d'autres parties (202, 204) stratifiées à proximité de ladite partie (203) ou dans un plan de stratification d'une partie, sur laquelle est formé le canal d'écoulement de division de dispersion (211) permettant de distribuer une phase de dispersion à ladite pluralité de canaux d'écoulement d'admission de phase de dispersion (211) et audit canal d'écoulement en gaine (212) ou audit canal d'écoulement de mélange agrandi (213), ou d'autres parties (202, 204) stratifiées à proximité de l'une quelconque desdites parties.
  2. L'appareil d'émulsification (104), tel que décrit dans la revendication 1, dans lequel
    lesdits canaux d'écoulement d'admission de phase continue (302) sont formés en au moins deux exemplaires ou plus et sont disposés de manière à être axialement symétriques à un axe dudit canal d'écoulement d'admission de phase de dispersion (211) et dudit canal d'écoulement de mélange (212).
  3. L'appareil d'émulsification (104), tel que décrit dans la revendication 1, dans lequel
    ledit canal d'écoulement en gaine (212) et ledit canal d'écoulement de mélange agrandi (213) sont formés sur des parties séparées (203, 204), respectivement.
  4. L'appareil d'émulsification (104), tel que décrit dans la revendication 1, dans lequel
    un canal d'écoulement de division de phase continue (301) reliant chacun des canaux d'écoulement d'admission de phase continue (302) est formé dans le plan dans lequel se trouve le canal d'écoulement d'admission de phase continue (302).
  5. L'appareil d'émulsification (104), tel que décrit dans la revendication 1, dans lequel
    un canal d'écoulement en gaine (212), permettant de combiner les liquides s'écoulant à travers ladite pluralité de canaux d'écoulement en gaine ou ledit canal d'écoulement de mélange agrandi (213), est formé dans un plan de stratification de ladite partie (202), sur laquelle est formé ledit canal d'écoulement d'admission de phase de dispersion (211), ou d'autres parties (201, 203) stratifiées à proximité de ladite partie (202) ou dans un plan de stratification d'une partie, sur laquelle est formé le canal d'écoulement de division de dispersion (211) permettant de distribuer une phase de dispersion à ladite pluralité de canaux d'écoulement d'admission de phase de dispersion (211) et audit canal d'écoulement en gaine (212) ou audit canal d'écoulement de mélange agrandi (213), ou d'autres parties stratifiées à proximité de l'une quelconque desdites parties.
EP08014632A 2007-09-06 2008-08-18 Appareil d'émulsification Not-in-force EP2033706B1 (fr)

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JP2007230922A JP5023902B2 (ja) 2007-09-06 2007-09-06 乳化装置

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EP2033706A2 EP2033706A2 (fr) 2009-03-11
EP2033706A3 EP2033706A3 (fr) 2009-11-11
EP2033706B1 true EP2033706B1 (fr) 2012-11-28

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CN (1) CN101380553A (fr)

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EP2033706A2 (fr) 2009-03-11

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