Classifications

• • E—FIXED CONSTRUCTIONS
  • E04—BUILDING
  • E04B—GENERAL BUILDING CONSTRUCTIONS; WALLS, e.g. PARTITIONS; ROOFS; FLOORS; CEILINGS; INSULATION OR OTHER PROTECTION OF BUILDINGS
  • E04B1/00—Constructions in general; Structures which are not restricted either to walls, e.g. partitions, or floors or ceilings or roofs
  • E04B1/343—Structures characterised by movable, separable, or collapsible parts, e.g. for transport
  • E04B1/344—Structures characterised by movable, separable, or collapsible parts, e.g. for transport with hinged parts
  • E04B1/3442—Structures characterised by movable, separable, or collapsible parts, e.g. for transport with hinged parts folding out from a core cell
  • E04B1/3444—Structures characterised by movable, separable, or collapsible parts, e.g. for transport with hinged parts folding out from a core cell with only lateral unfolding
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B60—VEHICLES IN GENERAL
  • B60P—VEHICLES ADAPTED FOR LOAD TRANSPORTATION OR TO TRANSPORT, TO CARRY, OR TO COMPRISE SPECIAL LOADS OR OBJECTS
  • B60P3/00—Vehicles adapted to transport, to carry or to comprise special loads or objects
  • B60P3/005—Vehicles adapted to transport, to carry or to comprise special loads or objects for use in contaminated areas, e.g. N.B.C. intervention vehicles
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B60—VEHICLES IN GENERAL
  • B60P—VEHICLES ADAPTED FOR LOAD TRANSPORTATION OR TO TRANSPORT, TO CARRY, OR TO COMPRISE SPECIAL LOADS OR OBJECTS
  • B60P3/00—Vehicles adapted to transport, to carry or to comprise special loads or objects
  • B60P3/14—Vehicles adapted to transport, to carry or to comprise special loads or objects the object being a workshop for servicing, for maintenance, or for carrying workmen during work
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B60—VEHICLES IN GENERAL
  • B60P—VEHICLES ADAPTED FOR LOAD TRANSPORTATION OR TO TRANSPORT, TO CARRY, OR TO COMPRISE SPECIAL LOADS OR OBJECTS
  • B60P3/00—Vehicles adapted to transport, to carry or to comprise special loads or objects
  • B60P3/32—Vehicles adapted to transport, to carry or to comprise special loads or objects comprising living accommodation for people, e.g. caravans, camping, or like vehicles
  • B60P3/34—Vehicles adapted to transport, to carry or to comprise special loads or objects comprising living accommodation for people, e.g. caravans, camping, or like vehicles the living accommodation being expansible, collapsible or capable of rearrangement
• • E—FIXED CONSTRUCTIONS
  • E04—BUILDING
  • E04H—BUILDINGS OR LIKE STRUCTURES FOR PARTICULAR PURPOSES; SWIMMING OR SPLASH BATHS OR POOLS; MASTS; FENCING; TENTS OR CANOPIES, IN GENERAL
  • E04H1/00—Buildings or groups of buildings for dwelling or office purposes; General layout, e.g. modular co-ordination or staggered storeys
  • E04H1/12—Small buildings or other erections for limited occupation, erected in the open air or arranged in buildings, e.g. kiosks, waiting shelters for bus stops or for filling stations, roofs for railway platforms, watchmen's huts or dressing cubicles
  • E04H1/1277—Shelters for decontamination
• • E—FIXED CONSTRUCTIONS
  • E04—BUILDING
  • E04H—BUILDINGS OR LIKE STRUCTURES FOR PARTICULAR PURPOSES; SWIMMING OR SPLASH BATHS OR POOLS; MASTS; FENCING; TENTS OR CANOPIES, IN GENERAL
  • E04H3/00—Buildings or groups of buildings for public or similar purposes; Institutions, e.g. infirmaries or prisons
  • E04H3/08—Hospitals, infirmaries, or the like; Schools; Prisons

Definitions

• the present invention relates to a mobile laboratory for the analysis of pathogens.
• Pathogens are classified according to their risk to health. In particular, their virulence, infectious dose, mode of transmission, host range, incubation and availability of preventive measures and treatments are considered. Generally four levels of risk are defined: - Risk group 1: low risk for the person and low for the community;
• - Risk Group 2 Moderate risk for the person, low for the community
• - Risk Group 4 high risk for the person, high for the community. Pathogens in this group are usually mentioned for bioterrorist attacks and for which no treatment or vaccine is available.
• - L2 basic laboratory for handling low pathogenic agents (risk group 2);
• - L3 containment laboratory for the handling of highly pathogenic biological agents for the individual and low pathogen at the community level (risk group 3);
• a team of specialists takes samples (water, gas, debris, animals, skin samples, ...) on the contaminated area. These samples are then packaged and transported by a specialized vehicle to a hospital center equipped with an L4 type analysis laboratory to maintain a maximum level of safety until the identification of pathogens. Once the diagnosis is made, the information on the nature of the risk is transmitted to the competent authorities who take the appropriate measures.
• the specialized vehicles carrying the samples are at best equipped with an L3 biological safety cabinet, no diagnosis can be made within the same vehicle.
• there are very few centers with an L4-type laboratory so the time it takes to transport samples from the contaminated area to the laboratory may take several hours. This time lapse between the taking of samples and the transmission of information on the nature of the risk to the competent authorities is therefore not optimal, which is particularly detrimental to the spread of pathogens and the contamination of a growing number of individuals.
• a first objective of the invention is therefore to provide a transportable mobile laboratory configured to handle highly pathogenic agents for the individual and the community (laboratory type L4).
• Patent FR 2,821,869 discloses a transportable mobile container defining a base room and comprising at least one deployable wall to form an annex. This type of container is particularly advantageous because during its transport by vehicle, its footprint is limited to that of the base room and when deployed in the field, it offers more space available.
• transportable mobile containers are not suitable for handling pathogens because they do not have sufficient containment.
• a second objective of the invention is to adapt the transportable mobile containers and in particular those of the type described in patent FR 2,821,869 (ALSTOM) in order to be able to carry out, in complete safety, a first analysis of the pathogens directly on the contaminated area.
• ALSTOM a first analysis of the pathogens directly on the contaminated area.
• the invention also aims to provide a mobile laboratory of simple design and quickly operational on the contaminated area.
• Another object of the invention is to provide a mobile radiological identification unit and / or biological and / or chemical capable of operating autonomously on contaminated areas.
• Another object of the invention is to provide an autonomous set of radiological and / or biological and / or chemical identification, easily transportable on all types of contaminated areas.
• the invention thus relates to a laboratory formed of a transportable mobile container defining a base room, the interior space of said room being isolated from the outside via a sealed box inserted in said room, said box comprising a sealed zone for the analysis of pathogens arranged with a pressure device for maintaining the interior of said zone under negative pressure with respect to its external environment, said laboratory being remarkable in that the watertight case comprises:
• a third sealed airlock communicating between said sealed zone for the analysis of pathogens and said first airlock, the entry into the zone for the analysis of pathogens being done only by said second lock.
• the claimed characteristics make it possible to confine the analysis zone perfectly, prevent the pathogens from freely emerging from the latter and make it possible to create a highly secure L4-type laboratory.
• the third sealed chamber is the only lock to leave the sealed zone for the analysis of pathogens.
• the third sealed chamber is an autoclave with two inlets, the second sealed chamber being the only chamber able to leave the sealed zone for agent analysis. pathogens.
• the container comprises at least one deployable wall forming an annex to the zone for the analysis of pathogens.
• the container comprises at least one deployable wall forming an annex to the zone for the analysis of pathogens.
• the container has two deployable side walls forming two annexes to the area for the analysis of pathogens, the watertight box being disposed within the base of said container. In this way, it is possible to have a laboratory offering space to work in optimal conditions.
• the second airlock is arranged with a pressure device intended to maintain a positive pressure gradient between said second airlock and the airtight zone for the analysis of pathogens "(Pse ⁇ nd sas - Pzo ⁇ e analysis> 0.) Given this pressure gradient, when personnel enters or leaves from the analysis zone via the second airlock, the air circulates one way to said analysis zone, which helps to improve the retention of pathogens.
• the second sealed airlock is arranged with a pressure device intended to maintain a negative pressure gradient between said second airlock and the first airlock of protection equipment (Ppremier sas - Pse ⁇ nd sas> 0). Given this pressure gradient, when personnel enters the second airlock through the first airlock protective equipment, the air flows one way to said second airlock, which helps to improve the retention of pathogens.
• the third sealed airlock is arranged with a pressure device intended to maintain a negative pressure gradient between said third airlock and the first airlock (Ppremier sas - Ptroisieme sas> 0). Given this pressure gradient, when personnel leave the analysis zone via the third airlock, the air circulates one way to said area, which helps to improve the retention of pathogens.
• the watertight box is made from a molded part of hollow parallelepipedal shape, without a right angle and without part inaccessible for cleaning.
• the watertight chamber is formed of clean room panels joined together according to the characteristics of the L4 type laboratories, the connection between the side walls of said box and the floor of the container being made by through a seal and a heat-welded coating disposed within said housing.
• an analysis device R.T P.C.R. Real Time Polymerase Chain Reaction
• R.T P.C.R. Real Time Polymerase Chain Reaction
• a P.C.R. analysis device Polymerase Chain Reaction
• This device makes it possible to identify unknown pathogens in less than seventy-two hours.
• the watertight case comprises a first lock of protective equipment, a second sealed inlet / outlet airlock, a third decontamination-proof shower chamber arranged with a pressure device, the zone for the pathogen analysis being only accessible by said third chamber.
• the pressure device is arranged with the area for pathogen analysis is an air extractor combined with HEPA filters.
• the area for pathogen analysis is equipped with a pressurized air supply adapted for scuba work.
• gable panels and panels roof and floor are movably mounted in the base room between a folded position where they are stored in said base room and an extended position where they partition the annex.
• the gable panels are pivotally mounted about a vertical axis fixed on the structure of the base room or on the side walls and the roof and floor panels are pivotally mounted about a horizontal axis fixed on the structure of the room. base or on the side walls.
• an external interface is disposed on a wall of the base room, said interface comprising means of connection to sources of electrical energy, air and of water.
• Another aspect of the invention relates to a mobile radiological and / or biological and / or chemical identification unit constituted by the combination of the mobile laboratory object of the invention equipped with the external interface defined above and a independent servicing module equipped with a generator, an air compressor and / or a vacuum pump and a water treatment device.
• the laboratory according to the invention can thus operate completely autonomously on the contaminated areas.
• said service module comprises an interface connected to the generator, to the air compressor and / or to the vacuum pump and the water treatment device and comprising connecting means intended to be connected to the laboratory interface.
• Yet another aspect of the invention relates to an autonomous set of radiological and / or biological and / or chemical identification constituted by the combination of a vehicle in which is arranged the laboratory according to the invention.
• FIG. 1 is a perspective view of a deployable container
• FIG. 2a is a schematic view in horizontal section of the container of FIG. 1 in the deployed position
• FIG. 2b is a schematic view in horizontal section of the container of FIG. 1 in the folded position
• FIG. 2c is a schematic vertical sectional view of the Figure 1 container in the extended position
• - Figure 2d is a schematic vertical sectional view of the container of Figure 1 in the folded position
• FIG. 3a is a schematic view in horizontal section of the laboratory object of the invention in the deployed position arranged with its servitude module
• FIG. 3b is a schematic view in horizontal section of the laboratory object of the invention in the deployed position and arranged with its servicing module, in a variant embodiment
• FIG. 3c is a schematic view in horizontal section of the laboratory object of the invention in the deployed position and arranged with its service module, in another variant embodiment;
• FIG. 4a is a schematic view in vertical section of the container in FIG. deployed position showing the arrangement of the watertight case,
• FIG. 4b is a diagrammatic view in vertical section of the container in the deployed position showing the arrangement of the watertight case in a variant embodiment
• RECTIFIED SHEET (RULE 91)
• ISA / EP - Figure 5 is a schematic view of the mobile assembly object of the invention.
• the laboratory object of the invention is designed to rapidly intervene in areas contaminated by biological, chemical or radioactive agents, whether in the context of a terrorist attack or an industrial accident and to carry out directly on the contaminated zone. an initial analysis of pathogens to inform the relevant authorities in real time to take the necessary decisions quickly regarding emergency medical and decontamination measures to be put in place. Samples taken will then be transported to specialized laboratories for further detailed analysis.
• a transportable mobile container that is to say a container usually used for the transport of equipment or merchandise and able to be fixed temporarily or permanently on the trailer of a truck.
• FIG. 1 there is used a container of 20 parallelepipedal feet formed of a roof 1a, a floor 1b, a rear wall 1c and a front wall 1d provided with a door 1 "d These four elements are fixed together, possibly via a frame 2 and determine a base room 10 having a fixed size ( Figures 2a to 2d).
• two walls 3a and 3b are deployably mounted to form two extensions 30a and 30b to the base room 10.
• the walls 3a and 3b are in the folded position ( Figure 2b) , the bulk of the container is limited to the size of the base room 10.
• the size of the container is increased by the size of the two annexes 30a and 3b to have a total usable area of about 30 m.
• the two annexes 30a and 30b are respectively accessible by gates 30'a and 30'b.
• the two side walls 3a and 3b of the base room 10 are mounted to move in translation through guide means 4.
• the guide means used may be guide bars fixed on the walls 3a and 3b and sliding in raceways arranged at the roof 1a and / or the floor 1b. Any other equivalent guiding means may be used.
• the deployment of the walls 3a and 3b can be performed manually, but the guide means 4 are advantageously coupled to a motorization of known type.
• closing means are provided for partitioning the annexes 30a and 30b.
• gable panels 3c mounted movably in the base room 10 are preferably used between a folded position where they are stored in said base unit ( Figure 2a) and an extended position where they partition said annexes when the walls 3a and 3b are themselves deployed ( Figure 2b).
• the gable panels 3c are pivotally mounted about a vertical axis fixed on the structure of the base room 10 or on the structure of the walls 3a and 3b.
• roof and floor panels 3d movably mounted in the base room 10, between a folded position where they are stored in said base room ( Figure 2c) and an extended position where they partition said annexes when the walls 3a and 3b are themselves deployed (Figure 2c).
• the roof and floor boards 3d are pivotally mounted about a horizontal axis fixed on the structure of the base room 10 or on the structure of the walls 3a and 3b. The deployment of the container is then very quickly: after deploying the two walls 3a and 3b, it is sufficient to rotate around their respective axis first 3d roof panels and floor and 3c gable panels, a device of maintaining in temporary position the various panels being provided.
• the closing means for partitioning the annexes 30a and 30b are sealed tarpaulins attached to the structure of the base room 10 and to the structure of the walls 3a and 3b so that said tarpaulins automatically put in place when said walls are deployed.
• the interior space of the base room 10 is isolated from the outside through a sealed box 5 inserted in said room.
• the box 5 is advantageously made from a hollow parallelepiped shaped molded part without a right angle and inaccessible parts for cleaning.
• the box 5 is formed of clean room panels joined together according to the characteristics of type L4 laboratories, the connection between the side walls of said box and the floor 1b of the container being made through a seal 91 and a heat-welded coating 90 disposed within said housing.
• the walls of the transportable mobile container are joined together according to the characteristics of the L4 type laboratories. Box 5 has a zone for the analysis of pathogens 5d,
• 5Od, 50Od, of about 9 m 2 arranged with a pressure device for maintaining the interior of said zone under negative pressure relative to the external environment.
• An alarm system is provided to detect any unacceptable change in pressure.
• pressure device in the sense of the present invention, a device adapted to regulate the pressure of a room (positive or negative pressure) according to a given instruction.
• the pressure device used in the pathogen analysis zone 5d, 50d, 50Od is preferably an air extractor combined with HEPA filters.
• a discharge fan coupled with a backup fan is used. Any other equivalent pressure device may be used.
• the air entering the analysis zone 5d, 50d, 50Od, is conditioned and treated by passing on HEPA filters mounted in series with prior filters.
• a device for decontaminating the effluents extracted from said box is provided to prevent any release of pathogens in the external environment.
• heat and / or chemical agents of the Sanytex® type are used as means of action.
• Solid waste (consumables, pipettes, culture media, protective clothing, etc.) are decontaminated through autoclaves or incinerators.
• An automatic FM200® gas fire detection and suppression system is planned in the area for the analysis of 5d, 50d, 50Od pathogens. The detection is carried out by smoke and temperature sensors placed on the ceiling of the whole zone for the analysis of pathogens 5d, 50d, 50Od. Manual-operated emergency fire extinguishers are also easily accessible to staff.
• the box 5 is also equipped with a reserve of hot and cold water of about 2 m 3 arranged with a water booster.
• the box 5 advantageously consists of:
• This first chamber is accessible from the outside by a door 5'a sealed equipped with a closed closure system type badge.
• a pictogram is provided on the door 5'a to indicate the biological danger.
• the first airlock 5a is preferably arranged with a pressure device for maintaining a positive pressure gradient between the external environment and said airlock (outside - first airlock> 0).
• the first airlock 5a is maintained at a negative pressure of between -10 Pa and -20 Pa.
• a second input / output sealed airlock 5b serving as a transition between the first lock of protective equipment 5a and the third decontamination shower enclosure 5c.
• This second airlock 5b is accessible from the first airlock 5a by a sealed 5'b door equipped with a closed closure system of the badge type.
• the second lock input / output 5b is preferably arranged with a pressure device for maintaining a positive pressure gradient between the first lock chamber 5a and said second lock (P first-mentioned sas - Pse ⁇ nd sas> 0).
• the second airlock 5b is maintained at a negative pressure of between -10 Pa and -20 Pa.
• a third sealed chamber 5c single access to the analysis zone 5d.
• This third chamber is accessible from the second chamber 5a by a door 5'c sealed equipped with a closed closure system type badge.
• the third airlock 5c is arranged with a pressure device for maintaining a positive pressure gradient between said third airlock 5c and the analysis zone 5d (Pthird sas - Analysis zone> 0). Due to this positive pressure gradient, the pathogens manipulated in the analysis zone 5d and suspended in the air can not freely exit through the third chamber 5c.
• the pressure device is of the type known to those skilled in the art.
• the analysis zone 5d is maintained at a pressure of between -20 Pa and -80 Pa, preferably -60 Pa and the third lock 5c is maintained at a pressure between -10 Pa and -30 Pa, preferably -20 Pa Pa.
• the third chamber 5c is maintained at a pressure of between +20 Pa and +80 Pa, preferably +60 Pa.
• the casing 5 advantageously consists of: a first lock of protective equipment 50a in which the staff wears a protective garment consisting of an integral combination and a diving suit.
• This first chamber is accessible from the outside by a 50'a waterproof door equipped with a closed closure system of the badge type.
• a pictogram is provided on the door 50'a to indicate the biological danger.
• the first airlock 50a is preferentially arranged with a pressure device for maintaining a positive pressure gradient between the external environment and said airlock (outside - first airlock> 0).
• the first airlock 50a is maintained at a negative pressure of between -10 Pa and -20 Pa.
• a second airlock 50b input, single access to the analysis zone
• This second chamber is accessible from the first airlock 50a by a sealed 50'b door equipped with a closed closure system of the badge type.
• the second airlock 50b is arranged with a pressure device intended to maintain a positive pressure gradient between said second chamber 50b and the analysis zone 50d (Pse ⁇ nd sas - analysis zone> 0) and advantageously between the first airlock 50a and said second airlock (Ppremier sas - Pse ⁇ nd sas> 0). Because of this positive pressure gradient, the pathogens manipulated in the analysis zone 50d and suspended in the air can not exit freely by said second airlock.
• the pressure device is of the type known to those skilled in the art.
• the second lock 50b is maintained at a pressure between -10 Pa and -30 Pa, preferably -20 Pa. In an alternative embodiment, the second lock 50b is maintained at a pressure of between +20 Pa and +80 Pa preferentially +60 Pa.
• the analysis zone 50d is maintained at a pressure of between -20 Pa and -80 Pa 1, preferably -60 Pa.
• a third sealed airlock 50c output, single output of the analysis zone 5Od is accessible from the analysis zone 50d by a 50 "watertight door equipped with a badge-type controlled closure system and communicates with the first airlock 50a
• the third airlock 50c is arranged with a device pressure device for maintaining a positive pressure gradient between said third airlock 50c and the analysis zone 50d (third analysis chamber - analysis zone> 0) and advantageously between the first airlock 50a and said third sluice (P pr Emier sas - Pse ⁇ nd sas> 0). Because of this positive pressure gradient, the pathogens manipulated in the analysis zone 50d and suspended in the air can not exit freely by said third chamber.
• the pressure device is of the type known to those skilled in the art.
• the third chamber 50c is maintained at a pressure of between -10 Pa and -30 Pa, preferably -20 Pa.
• the third chamber 50c is maintained at a pressure of between +20 Pa and +80 Pa preferentially +60 Pa.
• the box 5 advantageously consists of:
• a first lock of protective equipment 500a in which the staff wears a protective clothing consisting of an integral suit and a diving suit.
• This first airlock is accessible from the outside by a door 500'a sealed equipped with a closed closure system type badge.
• a pictogram is provided on the door 500'a to indicate the biological danger.
• a technical room 58 can be arranged in the first chamber 500a.
• the first airlock 500a is preferably arranged with a pressure device for maintaining a positive pressure gradient between the external environment and said airlock (outer - first airlock> 0). In practice, the pressure prevailing in the first airlock 500a is about +300 Pa.
• a second airlock 500b the only means of entry into the analysis zone 50Od.
• This second chamber is accessible from the first chamber 500a by a 500'b sealed door equipped with a closed closure system type badge.
• the second airlock 500b is preferably arranged with a pressure device intended to maintain a positive pressure gradient between said second chamber 500b and the analysis zone 50Od (Pse ⁇ nd sas - analysis zone> 0) and advantageously between the first sas 500a and said second airlock (Ppremier sas - Psecond sas> 0). Because of this positive pressure gradient, the pathogens handled in the 50Od analysis zone and in suspension in the air can not not to leave freely by said second airlock when the personnel enters or leaves the latter.
• the pressure device is of the type known to those skilled in the art.
• the second airlock 500b is maintained at a pressure of approximately -300 Pa.
• the second airlock 500b is maintained at a pressure of approximately +300 Pa.
• the second airlock 500b is advantageously equipped with a automatic decontamination shower as described below.
• the analysis zone 50Od is maintained at a pressure of approximately -300 Pa.
• a third airlock 500c accessible from the analysis zone 50Od by a 500 "watertight door equipped with a regulated closure system of the badge type
• This third airlock communicates with the first airlock 500a.
• sas 500c is advantageously arranged with a pressure device intended to maintain a positive pressure gradient between said third chamber 500c and the analysis zone 50Od (Ptheme third chamber - analysis zone> 0) and advantageously between the first chamber 500a and said third chamber (Ppremiersas - Pse ⁇ nd sas> 0).
• the third lock 500c is maintained at a pressure of approximately -300 Pa. realization, it can be maintained at a pressure of about 300 Pa
• the third lock can be:. o either the single lock for outputting 50Od of the analysis zone. or a double-entry autoclave, that is to say accessible from the 50Od analysis zone or accessible from the first equipment lock 500a.
• the second airlock 500b is the only airlock to exit the 50Od analysis zone.
• the different locks are equipped with a pressure device making it possible to balance the pressure of an airlock with the other.
• This feature makes it easier to open the different doors.
• the pressure balance is in relation to the pressure in the airlock where the person is and the pressure in the room where the person wants to go.
• the third airlock 5c, 50c, 500c is advantageously equipped with a shower to decontaminate staff when it leaves the area for the analysis of pathogens 5d, 50d, 50Od.
• a shower to decontaminate staff when it leaves the area for the analysis of pathogens 5d, 50d, 50Od.
• the decontamination system automatically starts for about 4 minutes to sprinkle personnel with a chlorine-based decontaminant solution.
• the decontamination shower is followed by a 2 minute rinse shower.
• the personnel enters the second airlock 5b, removes its protective clothing and incinerates the latter through an incinerator provided for this purpose .
• An autoclave can also be used in an equivalent way.
• the shower can automatically start for one minute when the door 5'd is closed. This decontamination ensures the decontamination of the air that has entered the third chamber 5c.
• the personnel enters the first lock of protective equipment 50a, 500a by a 50'c, 500'c sealed door, removes his protective clothing and incinerates the latter through a planned incinerator for this purpose.
• An autoclave can also be used in an equivalent way.
• said second airlock 50Od is the only output of the analysis zone 50Od (embodiment of Figure 3c)
• said second airlock is advantageously equipped with a shower to decontaminate personnel of the type described above.
• personnel leave the area for the 50Od pathogen analysis and enter the second chamber 500b, it closes the 500'd door and the decontamination shower automatically turns on for about 4 minutes followed by 2 minutes rinse shower.
• the personnel enters the first lock of protective equipment 500a by the 500'b waterproof door, removes his protective clothing and incinerates the latter through an incinerator provided for this purpose.
• An autoclave can also be used in an equivalent way.
• the area for pathogen analysis 5d, 50d, 50Od 1 is equipped with a pressurized air supply suitable for scuba work. It is in this case a microbiological safety laboratory at level L4 "scuba". When personnel are connected to this supply, all protective clothing is in positive pressure relative to the area for the analysis of pathogens 5d, 5Od, 50Od 1 so that in case of accidental tear, air exits the garment and prevents the pathogens from coming into contact with the individual.
• the pressurized air supply for scuba work is carried out by means of a compressor provided for this purpose, but pressurized breathable air rescue cylinders are provided in the area for the analysis of pathogens 5d. 5Od 1 50Od.
• Staff located outside the area for pathogen analysis 5d, 50d, 50Od, are in constant communication with the personnel within the area through microphones arranged in the spacesuits and activated by voice and leave their hands free.
• Other equivalent means of communication may be used such as intercoms, telephone, satellite phone jacks, fax machine, network computer, etc.
• These means of communication are preferably coupled to means of remote diagnosis and / or retransmission of data and / or video imagery to transmit information as quickly as possible to the competent authorities.
• the transmission of data is done in real time by a satellite system to allow rapid decision-making authorities.
• An observation window 56 is arranged on one of the walls of the caisson 5 so that the personnel located in the annex 30a can permanently observe the personnel located in the zone for the analysis of pathogens 5d, 50d, 50Od, and take all necessary steps in case of incidents.
• An equivalent system of video can also be used.
• the rescue personnel can break the observation window 56 to quickly intervene in the area for the analysis of pathogens 5d, 50d, 50Od.
• the observation window 56 is of the waterproof type, resistant to high pressure gradients.
• An inflation seal consisting of a membrane into which pressurized air is injected, is disposed around the window 56 to form a seal. The removal of the observation window 56 during the establishment of the laboratory object of the invention allows to enter (and exit) the equipment used in the area for the analysis of pathogens 5d, 50d, 50Od.
• the area for pathogen analysis 5d, 50d, 50Od is equipped with a glove box 51 accessible via a
• the glove box 51 is coupled to a microbiological safety station 53 with a laminar flow hood (type III).
• a bench 54 is equipped with a CO2 incubator, a microscope, a refrigerator, a double-entry autoclave, sinks whose taps are maneuverable without hands, a water bath and small basic materials (vortex, automatic pipettes, ).
• a single or double inlet autoclave may be disposed directly in the analysis zone 5d, 50d, 50Od.
• the space gained in the analysis zone 50Od makes it possible to provide a sheath 57 in which the air intake systems will be positioned. ventilation and / or pressure devices.
• An RT analysis device. P.C.R. (Real Time Polymerase Chain Reaction) 55 is also intended to select and multiply an identifiable gene or chain portion of DNA or RNA. This device makes it possible to identify in less than two hours the most common pathogens.
• a P. CR analysis device. (Polymerase Chain Reaction) 55 ' is also intended to select and multiply an identifiable gene or chain portion of DNA or RNA. This device makes it possible to identify unknown pathogens in less than seventy-two hours.
• Annexes 30a and 30b comprise radiological and chemical detection means: flame photometry detectors 31, fixed or mobile mass spectrometer 32, detection apparatus 33 on the biological and / or chemical and / or radiological risk, coupled weather station 34 computer software for processing data, for calculating and predicting the propagation of zones contaminated by chemical agents, a radiation survey meter 35, a chemical warfare toxic detector 36, etc.
• the annexes 30a and 30b are arranged with a pressure device intended to maintain a gradient of positive pressure between the external environment and the said annexes (outside - Panexexe> 0).
• the annexes 30a and 30b are maintained at a negative pressure of between -10 Pa and -20 Pa.
• an independent servitude module 7 provides electrical energy, water and air laboratory 1 object of the invention.
• the combination of the laboratory 1 and the service module 7 is a mobile unit of radiological identification and / or biological and / or chemical operating completely independently and can easily be deployed on the contaminated area.
• the service module 7 is a transportable mobile container equipped with a generator 7a, an air compressor and / or a vacuum pump 7b and a water treatment device 7c by reverse osmosis .
• a backup power supply system is integrated in the laboratory 1, a second generator and a second air compressor are preferably provided in the service module 7.
• Access to the service module 7 is via a sealed door 7d equipped with a closed closure system of the badge type.
• An external interface 60 is disposed on a wall of the laboratory base 1 so as to be able to quickly connect the latter to the service module 7.
• the interface 60 comprises connection means 60a, 60b, 60c to the generator 7a, the air compressor and / or the vacuum pump 7b and the water treatment device 7c, type quick couplings known to those skilled in the art.
• the service module 7 comprises an interface 70 connected to the generator 7a, to the air compressor and / or to the vacuum pump 7b and to the water treatment device 7c, and comprising connection means. 70a, 70b, 70c intended to be respectively connected to connecting means 60a, 60b, 60c of the interface 60 of the laboratory object of the invention.
• connection between the service module 7 and the laboratory 1 is thus done very quickly by simply connecting the different connection means of the interfaces 60 and 70, for example by using quick connectors for the connection of water and water pipes. air and sockets for the connection of electric cables.
• the laboratory 1 object of the invention is intended for the actors of rescue operations, army, civil protection, firefighters and more particularly to the sectors of defense, security, health surveillance in the case of epidemiological studies , the chemical and petroleum industry.
• the laboratory 1 object of the invention and the service module 7 are arranged to be transported in a vehicle 8 4x4 type.
• the laboratory 1 and the service module 7 are mounted removably or in a fixed manner on a trailer 8a of the vehicle 8.
• the vehicle 8 comprises a cell in which is fixedly fixed the laboratory object of the 'invention.
• This laboratory may also include a confined area equipped with a half-suit for the handling of highly pathogenic germs classified L4. This combination forms an autonomous set of radiological and / or biological and / or chemical identification that can rapidly reach any type of contaminated area.
• a mobile robot implemented from the vehicle can, by means of a remote control system, take samples or transport radiological or chemical sensors at a distance of 2 to 3 km.

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• Engineering & Computer Science (AREA)
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• Electromagnetism (AREA)
• Apparatus Associated With Microorganisms And Enzymes (AREA)
• Apparatus For Disinfection Or Sterilisation (AREA)
• Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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• 2007
  • 2007-04-16 EP EP07731304A patent/EP2007953A1/de not_active Withdrawn
  • 2007-04-16 WO PCT/FR2007/000638 patent/WO2007119009A1/fr active Application Filing
  • 2007-04-16 MX MX2008013156A patent/MX2008013156A/es not_active Application Discontinuation
  • 2007-04-16 US US12/297,054 patent/US20100304658A1/en not_active Abandoned
  • 2007-04-16 JP JP2009504784A patent/JP2009533038A/ja active Pending
  • 2007-04-16 BR BRPI0709832-4A patent/BRPI0709832A2/pt not_active IP Right Cessation

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