EP2007312A4 - Formbasiertes verfahren für gerüstlose gewebezüchtung - Google Patents
Formbasiertes verfahren für gerüstlose gewebezüchtungInfo
- Publication number
- EP2007312A4 EP2007312A4 EP20070760209 EP07760209A EP2007312A4 EP 2007312 A4 EP2007312 A4 EP 2007312A4 EP 20070760209 EP20070760209 EP 20070760209 EP 07760209 A EP07760209 A EP 07760209A EP 2007312 A4 EP2007312 A4 EP 2007312A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- shape
- tissue engineering
- based approach
- scaffoldless
- scaffoldless tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/76—Agarose, agar-agar
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Vascular Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Urology & Nephrology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78985506P | 2006-04-05 | 2006-04-05 | |
US78985106P | 2006-04-05 | 2006-04-05 | |
US78985306P | 2006-04-05 | 2006-04-05 | |
PCT/US2007/066089 WO2007115336A2 (en) | 2004-07-09 | 2007-04-05 | A shape-based approach for scaffoldless tissue engineering |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2007312A2 EP2007312A2 (de) | 2008-12-31 |
EP2007312A4 true EP2007312A4 (de) | 2012-08-22 |
Family
ID=38564326
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20070760209 Withdrawn EP2007312A4 (de) | 2006-04-05 | 2007-04-05 | Formbasiertes verfahren für gerüstlose gewebezüchtung |
EP07760211A Withdrawn EP2007881A4 (de) | 2006-04-05 | 2007-04-05 | Gewebezüchtung mit menschlichen embryonischen stammzellen |
EP07760205A Withdrawn EP2007875A4 (de) | 2006-04-05 | 2007-04-05 | Zellen aus der lederhaut für gewebezüchtung |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07760211A Withdrawn EP2007881A4 (de) | 2006-04-05 | 2007-04-05 | Gewebezüchtung mit menschlichen embryonischen stammzellen |
EP07760205A Withdrawn EP2007875A4 (de) | 2006-04-05 | 2007-04-05 | Zellen aus der lederhaut für gewebezüchtung |
Country Status (4)
Country | Link |
---|---|
EP (3) | EP2007312A4 (de) |
AU (3) | AU2007234365A1 (de) |
CA (3) | CA2648648A1 (de) |
WO (3) | WO2007115337A2 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2404682T3 (es) | 2003-12-11 | 2013-05-28 | Isto Technologies Inc. | Sistema de cartílago particulado |
US8241905B2 (en) | 2004-02-24 | 2012-08-14 | The Curators Of The University Of Missouri | Self-assembling cell aggregates and methods of making engineered tissue using the same |
WO2010022074A1 (en) * | 2008-08-18 | 2010-02-25 | William Marsh Rice University | A decellularization method for scaffoldless tissue engineered articular cartilage or native cartilage tissue |
US20110212894A1 (en) * | 2004-07-09 | 2011-09-01 | Athanasiou Kyriacos A | Decellularization method for scaffoldless tissue engineered articular cartilage or native cartilage tissue |
US8480757B2 (en) | 2005-08-26 | 2013-07-09 | Zimmer, Inc. | Implants and methods for repair, replacement and treatment of disease |
US8163549B2 (en) | 2006-12-20 | 2012-04-24 | Zimmer Orthobiologics, Inc. | Method of obtaining viable small tissue particles and use for tissue repair |
US20090012629A1 (en) | 2007-04-12 | 2009-01-08 | Isto Technologies, Inc. | Compositions and methods for tissue repair |
JP2011512992A (ja) * | 2008-03-03 | 2011-04-28 | ウイリアム、マーシュ、ライス、ユーニヴァーサティ | 改良された組織工学的に作製された軟骨を組み立てる方法 |
SI2310491T1 (en) * | 2008-06-20 | 2018-07-31 | Universiteit Maastricht | Only composite tissue modules |
KR20170020942A (ko) | 2008-06-24 | 2017-02-24 | 더 큐레이터스 오브 더 유니버시티 오브 미주리 | 자가-조립가능 다세포체 및 이들을 이용하여 3차원 생물학적 구조체를 생산하는 방법 |
SG177694A1 (en) * | 2009-07-16 | 2012-02-28 | Biotime Inc | Methods and compositions for in vitro and in vivo chondrogenesis |
WO2012054195A2 (en) | 2010-10-21 | 2012-04-26 | Organovo, Inc. | Devices, systems, and methods for the fabrication of tissue |
US10865383B2 (en) | 2011-07-12 | 2020-12-15 | Lineage Cell Therapeutics, Inc. | Methods and formulations for orthopedic cell therapy |
US9499779B2 (en) | 2012-04-20 | 2016-11-22 | Organovo, Inc. | Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking |
US20140178343A1 (en) | 2012-12-21 | 2014-06-26 | Jian Q. Yao | Supports and methods for promoting integration of cartilage tissue explants |
US9442105B2 (en) | 2013-03-15 | 2016-09-13 | Organovo, Inc. | Engineered liver tissues, arrays thereof, and methods of making the same |
BR112016002149A2 (pt) | 2013-07-31 | 2017-08-01 | Organovo Inc | métodos, sistemas e dispositivos automatizados para a fabricação de tecido |
CA2944723C (en) | 2014-04-04 | 2023-03-14 | Organovo, Inc. | Engineered three-dimensional breast tissue, adipose tissue, and tumor disease model |
US9670443B2 (en) * | 2014-06-25 | 2017-06-06 | University Of Leeds | Tissue engineered constructs |
KR20170064547A (ko) | 2014-10-06 | 2017-06-09 | 오가노보, 인크. | 조작된 신장 조직, 이의 어레이, 및 이를 제조하는 방법 |
MA40598A (fr) | 2014-11-05 | 2017-09-13 | Oreal | Tissus cutanés tridimensionnels manipulés, ensembles correspondants et leurs procédés de production |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020106625A1 (en) * | 2002-02-07 | 2002-08-08 | Hung Clark T. | Bioreactor for generating functional cartilaginous tissue |
WO2006017176A2 (en) * | 2004-07-09 | 2006-02-16 | William Marsh Rice University | Scaffoldless constructs for tissue engineering of articular cartilage |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5944754A (en) * | 1995-11-09 | 1999-08-31 | University Of Massachusetts | Tissue re-surfacing with hydrogel-cell compositions |
BR0008714A (pt) * | 1999-03-02 | 2002-01-02 | Univ Massachusetts Public Inst | Linhagens celulares embriÈnicas ou tipo tronco produzidas por transplante nuclear de espécies cruzadas |
JP2004504834A (ja) * | 2000-08-01 | 2004-02-19 | イスム リサーチ ディベロップメント カンパニー | 胚性細胞の定方向分化 |
US20020132346A1 (en) * | 2001-03-08 | 2002-09-19 | Jose Cibelli | Use of RNA interference for the creation of lineage specific ES and other undifferentiated cells and production of differentiated cells in vitro by co-culture |
IL162132A0 (en) * | 2001-12-07 | 2005-11-20 | Geron Corp | Chondrocyte precursors derived from human embryonic stem cells |
JP2005531298A (ja) * | 2002-04-02 | 2005-10-20 | ウィリアム・マーシュ・ライス・ユニバーシティ | 軟骨の欠損を修復するための再分化細胞 |
US20040082063A1 (en) * | 2002-10-18 | 2004-04-29 | Reliance Life Sciences Pvt. Ltd. | Tissue-like organization of cells and macroscopic tissue-like constructs, generated by macromass culture of cells, and the method of macromass culture |
-
2007
- 2007-04-05 EP EP20070760209 patent/EP2007312A4/de not_active Withdrawn
- 2007-04-05 WO PCT/US2007/066092 patent/WO2007115337A2/en active Application Filing
- 2007-04-05 WO PCT/US2007/066085 patent/WO2007136936A2/en active Application Filing
- 2007-04-05 AU AU2007234365A patent/AU2007234365A1/en not_active Abandoned
- 2007-04-05 WO PCT/US2007/066089 patent/WO2007115336A2/en active Application Filing
- 2007-04-05 CA CA002648648A patent/CA2648648A1/en not_active Abandoned
- 2007-04-05 CA CA002648332A patent/CA2648332A1/en not_active Abandoned
- 2007-04-05 AU AU2007234366A patent/AU2007234366A1/en not_active Abandoned
- 2007-04-05 EP EP07760211A patent/EP2007881A4/de not_active Withdrawn
- 2007-04-05 AU AU2007254048A patent/AU2007254048A1/en not_active Abandoned
- 2007-04-05 CA CA002648327A patent/CA2648327A1/en not_active Abandoned
- 2007-04-05 EP EP07760205A patent/EP2007875A4/de not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020106625A1 (en) * | 2002-02-07 | 2002-08-08 | Hung Clark T. | Bioreactor for generating functional cartilaginous tissue |
WO2006017176A2 (en) * | 2004-07-09 | 2006-02-16 | William Marsh Rice University | Scaffoldless constructs for tissue engineering of articular cartilage |
Non-Patent Citations (1)
Title |
---|
C R LEE ET AL: "Modulation of the Contractile and Biosynthetic Activity of Chondroxytes Seeded in Collagen-Glycosaminoglycan Matrices", TISSUE ENGINEERING, vol. 9, no. 1, 1 January 2003 (2003-01-01), pages 27 - 36, XP055032370 * |
Also Published As
Publication number | Publication date |
---|---|
EP2007881A4 (de) | 2009-07-08 |
AU2007234365A1 (en) | 2007-10-11 |
AU2007234366A1 (en) | 2007-10-11 |
CA2648327A1 (en) | 2007-10-11 |
WO2007115336A3 (en) | 2008-05-22 |
EP2007881A2 (de) | 2008-12-31 |
WO2007136936A2 (en) | 2007-11-29 |
WO2007115337A2 (en) | 2007-10-11 |
WO2007136936A3 (en) | 2008-10-23 |
EP2007875A2 (de) | 2008-12-31 |
WO2007115336A2 (en) | 2007-10-11 |
EP2007875A4 (de) | 2009-12-16 |
WO2007115337A3 (en) | 2008-07-03 |
AU2007254048A1 (en) | 2007-11-29 |
EP2007312A2 (de) | 2008-12-31 |
CA2648332A1 (en) | 2007-10-11 |
WO2007115337A8 (en) | 2007-12-13 |
CA2648648A1 (en) | 2007-11-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20081104 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20120719 |
|
17Q | First examination report despatched |
Effective date: 20130506 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20150807 |