EP1985858B1 - Rollenpumpe - Google Patents
Rollenpumpe Download PDFInfo
- Publication number
- EP1985858B1 EP1985858B1 EP08012607A EP08012607A EP1985858B1 EP 1985858 B1 EP1985858 B1 EP 1985858B1 EP 08012607 A EP08012607 A EP 08012607A EP 08012607 A EP08012607 A EP 08012607A EP 1985858 B1 EP1985858 B1 EP 1985858B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- pump
- hose
- connector
- roller pump
- bed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000007704 transition Effects 0.000 claims description 6
- 239000012530 fluid Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 238000009423 ventilation Methods 0.000 description 4
- 238000005086 pumping Methods 0.000 description 2
- 238000005299 abrasion Methods 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 238000013022 venting Methods 0.000 description 1
Images
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
- F04B43/1253—Machines, pumps, or pumping installations having flexible working members having peristaltic action by using two or more rollers as squeezing elements, the rollers moving on an arc of a circle during squeezing
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
- F04C2/00—Rotary-piston machines or pumps
Definitions
- the invention consists of a roller pump according to the preamble of claim 1, as in the document US-A-4,674,962 is disclosed.
- roller pumps are for example also from the US 4,545,744 A known. They consist of a stator with a formed in this pump bed and a rotor for applying an arcuately insertable into the pump bed tube.
- a stator with a formed in this pump bed
- a rotor for applying an arcuately insertable into the pump bed tube.
- the object of the invention is to develop the generic roller pump such that liquid-carrying hoses can be used in a particularly space-saving manner.
- the advantages of the hose guide according to the invention are particularly advantageous when the connector is arranged laterally on the pump bed with horizontal alignment of the rotor axis.
- optimum ventilation of the tube segment can be achieved. Namely, it is ensured that air, which lies in the entrance area, rises by the buoyancy force. Even within the rise, the corresponding pinch rollers of the rotor engage in the hose segment lying in the pump bed and guarantee a forced conveyance of the corresponding air bubbles. It is similar at the exit of the hose segment. When the pinch rollers release the hose segment, the entrained air is already in the rising area of the hose segment. As a result, there is no force driving the air back into the pump.
- the roller pump has a control unit which determines the corresponding direction of rotation of the rotor as a function of the lateral orientation of the connection piece. So the rotor is turning counterclockwise Turned when the hoses cross on the right side and clockwise when the hoses cross on the left side.
- the insertable into the roller pump hose is connected to a connector, which is designed as an integrated cassette.
- a roller pump 10 with a pump bed 22 and an inserted tube 12 is shown, which is connected to a designed as an adapter fitting 14.
- a connector 14 At the connector 14 are as tubing also an afferent Hose 16 and a hose 18 leading away shown.
- the direction of the arrow indicates the direction of flow of the fluid within the hose.
- the led out of the pump bed ends of the tube intersect in this way in the fitting 14th
- the flexible hose 12 is continuously compressed in the direction of the arrow A with corresponding rollers 13, so that the corresponding pumping effect for the liquid results.
- tube shape can be described as alpha-form, in which the led out of the pump bed 22 ends of the tube 12 tangentially and are led out of the pump bed 22 crossing each other.
- the hose parts 16 and 18 can also be led out of the pump directly laterally (not shown).
- FIG. 2 different views of a designed as an injection molded roller pump housing 20 are shown.
- the Fig. 2 a) shows a top view from above, the Fig. 2 b) a side view, Fig. 2c) a view from the front and the Fig. 2 d) a perspective view from above, while the Fig. 2 e) a perspective view from below shows.
- a pump bed 22 is formed, in which the arcuate hose 12 is used in a manner not shown here in more detail.
- the pump bed 22 has an opening 24 towards one side.
- the lateral end portions of the opening 24 are formed by clip receptacles 26 and 28 of different shape.
- the Clips annoyingn 26 and 28 are, as from the Fig. 2 d) can be separated from the roller pump housing 20. They are fastened to the housing 20 with corresponding fastening pins 30 and exchangeable. The respective rotor with the corresponding rollers for loading the arcuately inserted into the pump bed tube 12 is not shown here.
- the Fig. 3 a) shows a plan view of an adapter piece 32, the opening 24 of the housing 20 according to Fig. 2 can close.
- Fig. 3 b) is a corresponding sectional view according to the section line IIIb-IIIb by Fig. 3 a) shown.
- Fig. 3c) is a corresponding sectional view corresponding to the section line IIIc-IIIc in Fig. 3 a) shown.
- the adapter 32 has corresponding connection regions 36 or 38 for the tubes 16 and 18 and connection regions 34 for the tube 12. If the corresponding pieces of tubing are connected, they can be clipped together with the adapter 32 in the housing 20, wherein they are determined by the corresponding clip receivers 26 and 28.
- the corresponding recesses 40 and 42 in the adapter 32 are respectively adapted to the shapes of the clip receivers 26 and 28.
- the adapters 32 can be differentiated in terms of color in order to be able to associate them more easily with the respective roller pump 10.
- a knob (not shown) is arranged, which cooperates with a built-in roller pump sensor to make the proper assembly of the connector or the corresponding preassembled hose set verifiable by the control unit of the roller pump.
- a hose set may comprise a hose connected to the adapter and to be inserted into the pump bed and corresponding hoses leading away from the pump.
- Fig. 4 shows a roller pump according to the invention 10.
- hose 12 is shown without roller pump housing.
- the direction of rotation of the rotor 11 is indicated by the direction of the arrow A.
- an integrated cassette 50 is provided in which various functional units can be realized.
- a pressure measuring device 52 integrated.
- the ends of the hose led out of the pump bed intersect in the connecting piece directly next to the rotor region of the pump, ie the opening of the pump bed.
- Optimum ventilation of the tube segment 12 also results in the liquid guide shown here. Air which rises in the inlet region of the tube 12 rises upward by the buoyancy force and is forcibly guided along the tube 12 within the rise by the pressure rollers of the rotor. As far as they arrive at the end region of the hose 12 (seen in the direction of arrow A), the entrained air is also in the ascending region of the hose 12, so that they continue to rise and be discharged through the hose 18.
- This advantageous ventilation results when the intersecting part of the tube is arranged on the right side and the rotor 11 simultaneously rotates counterclockwise. Alternatively, the advantageous venting results in the event that the intersecting part of the hose is on the left side when the rotor rotates clockwise.
- the construction of the roller pump according to the invention also makes possible a more flexible and space-saving design of the fluid guide even with an integrated cassette.
- the adapter 32 is, as stated above, in the housing 20 clipped. As can be seen in particular from the Fig. 2 b) results, the clip receivers 26 and 28 at the upper end nose-like projections 51, 53 on. When inserting the adapter 34, this gets under these projections, which represents the actual clip function.
- the one side of the clip recording forming right projection 51 is beyond the edge of the recess of the inserted adapter on than on the left side of the projection 53 (eg, about 1 mm compared to a few 10ths of mm).
- On the left side of the molding 42 of the adapter piece see. Fig. 3 Roundish (here approximated to a circular arc), while on the right hand side it is angular (reference numeral 40 in Figure 3 ).
- the ejection of the adapter via a pin 54 (see. Fig. 2 ).
- the pin is designed near the round clip receptacle 28, so that the adapter 34 is first separated from the housing on the round contact side when the pin 54 is actuated accordingly.
- the corresponding pin 54 can be extended controlled here in a manner not shown by the pump-side housing, so that the round side 42 of the adapter 32 snaps from the clip recording.
- the tilting movement created by the arrangement of the pin 54 when ejecting the adapter has another advantage.
- the roller pump 10 is equipped with two radial pins, as for example in the US 4,545,544 A is described.
- the two pins are mounted on opposite sides.
- the left side of the adapter 34 is raised and the right side of the adapter 34 is not raised, the lower pin can easily drive clockwise under the hose to lift it while the upper pin can easily pass over the still inserted hose.
- a pin can get caught in the pump hose system. This is prevented by the tilting movement when ejecting the adapter 32.
- the adapter 32 is designed such that it allows an edge-free connection between the pump hose segment 12 and the outer hose segments 16, 18, which, as in the Fig. 1 visible, different inner diameter exhibit. This is also in the Fig. 3b and 3c in that the openings 34 have a first width and the openings 36 and 38 have a second, smaller width. Immediately adjacent to this opening is a transition area. The openings of the transition region correspond to the inner diameters of the tube segments to be inserted. The transition region is inventively characterized by a steady transition of the inner diameter, in order to achieve a blood-compatible, homogeneous flow as possible.
- the crossing region of the two tube segments 16 and 18 is already in a range in which the inner diameters of the two lines are considerably reduced. This allows the invention a possible good and level alignment of the entire pump loop, so there is no excessive abrasion through the hose guide pins.
- the pin 54 can also serve as a sensor for a provided on the adapter 32 nubs.
- the pin 54 is moved vertically in a manner not shown by pressing the nubs, which can be detected by a light barrier also not shown here.
- section IIId-IIId as in Fig. 3d is shown, it can be seen that the distance at the circular recess 42 and the angular recess 40 of the adapter 32 is reduced from top to bottom. This allows a better demolding of the adapter during manufacture.
- second projection may be provided which acts as a stop of the tilting adapter 32.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- External Artificial Organs (AREA)
- Reciprocating Pumps (AREA)
- Massaging Devices (AREA)
- Details And Applications Of Rotary Liquid Pumps (AREA)
- Fuel-Injection Apparatus (AREA)
- Rotary Pumps (AREA)
- Details Of Reciprocating Pumps (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Liquid Developers In Electrophotography (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10009784A EP2275681B1 (de) | 2004-05-14 | 2005-05-12 | Rollenpumpe |
PL08012607T PL1985858T3 (pl) | 2004-05-14 | 2005-05-12 | Pompa rolkowa |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004024102 | 2004-05-14 | ||
EP05739618A EP1763636B1 (de) | 2004-05-14 | 2005-05-12 | Rollenpumpe |
Related Parent Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP05739618A Division EP1763636B1 (de) | 2004-05-14 | 2005-05-12 | Rollenpumpe |
EP05739618.6 Division | 2005-05-12 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10009784.9 Division-Into | 2010-09-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1985858A1 EP1985858A1 (de) | 2008-10-29 |
EP1985858B1 true EP1985858B1 (de) | 2010-12-01 |
Family
ID=34966716
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10009784A Active EP2275681B1 (de) | 2004-05-14 | 2005-05-12 | Rollenpumpe |
EP08012607A Active EP1985858B1 (de) | 2004-05-14 | 2005-05-12 | Rollenpumpe |
EP05739618A Active EP1763636B1 (de) | 2004-05-14 | 2005-05-12 | Rollenpumpe |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10009784A Active EP2275681B1 (de) | 2004-05-14 | 2005-05-12 | Rollenpumpe |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP05739618A Active EP1763636B1 (de) | 2004-05-14 | 2005-05-12 | Rollenpumpe |
Country Status (18)
Country | Link |
---|---|
US (3) | US7758324B2 (ja) |
EP (3) | EP2275681B1 (ja) |
JP (3) | JP4870663B2 (ja) |
KR (1) | KR101224674B1 (ja) |
CN (3) | CN101655082B (ja) |
AT (2) | ATE490407T1 (ja) |
AU (3) | AU2005243476B2 (ja) |
BR (3) | BR122017015656B1 (ja) |
CA (3) | CA2566054C (ja) |
DE (2) | DE502005010640D1 (ja) |
DK (2) | DK1985858T3 (ja) |
EA (3) | EA012669B1 (ja) |
ES (3) | ES2356026T3 (ja) |
HK (3) | HK1099898A1 (ja) |
PL (2) | PL1763636T3 (ja) |
PT (2) | PT1985858E (ja) |
SI (1) | SI1763636T1 (ja) |
WO (1) | WO2005111424A1 (ja) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102006008325B4 (de) * | 2006-02-20 | 2013-09-12 | W.O.M. World Of Medicine Ag | Schlauchkassette für eine peristaltische Pumpe |
JP5397747B2 (ja) | 2009-02-16 | 2014-01-22 | ニプロ株式会社 | チューブポンプ |
EA022698B1 (ru) * | 2009-04-23 | 2016-02-29 | Фрезениус Медикел Кеэ Дойчланд Гмбх | Кассета для обработки крови |
DE102009046406B4 (de) * | 2009-11-04 | 2012-04-26 | Fresenius Medical Care Deutschland Gmbh | Schlauchpumpe |
IT1400365B1 (it) † | 2010-06-07 | 2013-05-31 | Hemodec S R L | Apparecchiatura per il trattamento del sangue |
KR101006479B1 (ko) | 2010-10-06 | 2011-01-06 | 김은수 | 호스 압착력의 미세 조절이 용이한 호스 펌프 |
EP2514451A1 (en) * | 2011-04-21 | 2012-10-24 | SIS-TER S.p.A. | Tubular insert for extra-corporeal circuit |
EP2532999A1 (en) | 2011-06-09 | 2012-12-12 | SIS-TER S.p.A. | Heat exchange device |
ITTO20120386A1 (it) | 2012-04-30 | 2013-10-31 | F M S P A | Raccordo amovibile per pompa peristaltica |
US9746412B2 (en) | 2012-05-30 | 2017-08-29 | Iris International, Inc. | Flow cytometer |
DE102012105918A1 (de) * | 2012-07-03 | 2014-01-09 | B. Braun Avitum Ag | Multikonnektor und medizinisches Gerät zur extrakorporalen Blutbehandlung mit Multikonnektorerkennung |
EP2781234A1 (en) * | 2013-03-20 | 2014-09-24 | Fresenius Medical Care Deutschland GmbH | Tube for extra-corporeal circuit with double connector |
DE102013011717A1 (de) | 2013-07-15 | 2015-01-15 | Fresenius Medical Care Deutschland Gmbh | Verfahren zum Steuern einer Blutbehandlungsvorrichtung nach Abschluss einer Behandlung und Vorrichtungen |
DE102014103492A1 (de) | 2014-03-14 | 2015-09-17 | Fresenius Medical Care Deutschland Gmbh | Flüssigkeitskassette mit kipptoleranter Zentrierverrastung sowie Blutbehandlungsvorrichtung |
DE102014103507A1 (de) | 2014-03-14 | 2015-09-17 | Fresenius Medical Care Deutschland Gmbh | Medizinische Funktionsvorrichtung mit einem Ventilsitz für ein remanentes Rückschlagventil |
DE102014104320B3 (de) * | 2014-03-27 | 2015-08-06 | Ulrich Gmbh & Co. Kg | Schlauchpumpe mit Ausfädeleinrichtung |
MX2017006220A (es) * | 2014-12-12 | 2017-07-31 | Zevex Inc | Casete de bomba de infusion e interfaz de casete configurada para ayudar en la remocion del casete. |
DE102016005467A1 (de) * | 2016-05-06 | 2017-11-09 | Fresenius Medical Care Deutschland Gmbh | Medizinische Behandlungsvorrichtung und Schlauchset für eine medizinische Behandlungsvorrichtung sowie Verfahren zur Überwachung einer peristaltischen Schlauchpumpe |
CN107503920B (zh) * | 2017-09-21 | 2024-03-22 | 合肥华运机械制造有限公司 | 多工位软管泵 |
US11852129B2 (en) | 2017-09-26 | 2023-12-26 | Nipro Corporation | Tube set and tube pump provided with same |
KR102071646B1 (ko) | 2018-07-26 | 2020-01-31 | (주)오토일렉스 | 튜브펌프 |
DE102018121872A1 (de) | 2018-09-07 | 2020-03-12 | Fresenius Medical Care Deutschland Gmbh | Peristaltische Pumpe |
DE102018121868A1 (de) | 2018-09-07 | 2020-03-12 | Fresenius Medical Care Deutschland Gmbh | Peristaltische Pumpe |
DE102018121903A1 (de) | 2018-09-07 | 2020-03-12 | Fresenius Medical Care Deutschland Gmbh | Peristaltische Pumpe |
CN109331235B (zh) * | 2018-09-28 | 2020-11-27 | 赵亮 | 医用自动引流装置 |
DE102021116833A1 (de) | 2021-06-30 | 2023-01-05 | Fresenius Medical Care Deutschland Gmbh | Klemmelement für eine Pumpvorrichtung |
TWI823551B (zh) * | 2022-09-06 | 2023-11-21 | 牟敦剛 | 蠕動幫浦軟管安置結構與相應裝置 |
EP4438102A1 (en) | 2023-03-31 | 2024-10-02 | Fresenius Medical Care Deutschland GmbH | Connector for connecting a pump hose segment to a pump bed of a peristaltic pump |
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US2231579A (en) * | 1938-01-31 | 1941-02-11 | Downingtown Mfg Co | Pump |
US2651264A (en) * | 1951-02-10 | 1953-09-08 | Florez Company Inc De | Fluid pump |
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US4452599A (en) * | 1981-10-26 | 1984-06-05 | The Hospital For Sick Children | Method of delivering medical liquid by peristaltic tube pump |
US4545544A (en) | 1982-09-10 | 1985-10-08 | Figge International, Inc. | Fabric handling apparatus and method |
DE3326784C2 (de) * | 1983-07-25 | 1986-06-05 | Fresenius AG, 6380 Bad Homburg | Peristaltisch arbeitende Rollenpumpe |
US4685902A (en) * | 1983-08-24 | 1987-08-11 | Becton, Dickinson And Company | Disposable reservoir cassette |
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JPH06154310A (ja) * | 1992-11-16 | 1994-06-03 | Toray Ind Inc | チューブ引出し方向可変ポンプおよびチューブ引出し方向可変血液ポンプ、並びに該血液ポンプを用いた人工透析装置 |
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KR0127520Y1 (ko) * | 1994-11-30 | 1999-01-15 | 김재복 | 연삭기의 공작물위치 확인장치 |
JPH08334087A (ja) * | 1995-06-07 | 1996-12-17 | Seikouken Kk | ポンプ装置 |
US5630711A (en) * | 1995-09-08 | 1997-05-20 | Graymills Corporation | Peristaltic pump having a loop-shaped tube path |
RU2116511C1 (ru) * | 1996-04-29 | 1998-07-27 | Научно-исследовательский технологический институт | Перистальтический насос |
US5752813A (en) * | 1996-10-23 | 1998-05-19 | A.Z.E. Medical Inc. | Keyed cassette for dispensing pump |
US5927956A (en) * | 1998-09-01 | 1999-07-27 | Linvatec Corporation | Peristaltic pump tubing system with latching cassette |
US6164921A (en) * | 1998-11-09 | 2000-12-26 | Moubayed; Ahmad Maher | Curvilinear peristaltic pump having insertable tubing assembly |
JP4183315B2 (ja) * | 1998-11-17 | 2008-11-19 | 信越ポリマー株式会社 | ローラーポンプ用チューブ |
GB2349431B (en) * | 1999-04-29 | 2002-06-12 | Watson Marlow Ltd | Peristaltic pumps |
JP4607406B2 (ja) * | 1999-09-03 | 2011-01-05 | フェンウォール、インコーポレイテッド | プログラム可能な、流体圧作動血液処理システムおよび方法 |
DE19960668C1 (de) * | 1999-12-15 | 2001-08-16 | W O M Gmbh Physikalisch Medizi | Schlauchkasette für eine peristaltische Pumpe |
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KR100900638B1 (ko) * | 2002-08-27 | 2009-06-02 | 주식회사 포스코 | 롤그라인더의 롤 연결위치 확인장치 |
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-
2005
- 2005-05-12 AU AU2005243476A patent/AU2005243476B2/en active Active
- 2005-05-12 KR KR1020067023050A patent/KR101224674B1/ko active IP Right Grant
- 2005-05-12 WO PCT/EP2005/005191 patent/WO2005111424A1/de active IP Right Grant
- 2005-05-12 EA EA200602108A patent/EA012669B1/ru not_active IP Right Cessation
- 2005-05-12 EP EP10009784A patent/EP2275681B1/de active Active
- 2005-05-12 SI SI200530454T patent/SI1763636T1/sl unknown
- 2005-05-12 AT AT08012607T patent/ATE490407T1/de active
- 2005-05-12 CN CN200910149537.3A patent/CN101655082B/zh active Active
- 2005-05-12 CA CA2566054A patent/CA2566054C/en active Active
- 2005-05-12 US US11/596,353 patent/US7758324B2/en active Active
- 2005-05-12 BR BR122017015656-0A patent/BR122017015656B1/pt active IP Right Grant
- 2005-05-12 AT AT05739618T patent/ATE406520T1/de active
- 2005-05-12 DE DE502005010640T patent/DE502005010640D1/de active Active
- 2005-05-12 PL PL05739618T patent/PL1763636T3/pl unknown
- 2005-05-12 DK DK08012607.1T patent/DK1985858T3/da active
- 2005-05-12 PT PT08012607T patent/PT1985858E/pt unknown
- 2005-05-12 EA EA201000191A patent/EA017078B1/ru not_active IP Right Cessation
- 2005-05-12 EP EP08012607A patent/EP1985858B1/de active Active
- 2005-05-12 CA CA2872585A patent/CA2872585C/en active Active
- 2005-05-12 ES ES08012607T patent/ES2356026T3/es active Active
- 2005-05-12 ES ES10009784T patent/ES2401569T3/es active Active
- 2005-05-12 BR BR122017015660A patent/BR122017015660B1/pt active IP Right Grant
- 2005-05-12 CA CA2814817A patent/CA2814817C/en active Active
- 2005-05-12 JP JP2007512108A patent/JP4870663B2/ja active Active
- 2005-05-12 CN CNB200580014003XA patent/CN100523502C/zh active Active
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