EP1617818A1 - Formulierung, um ein antimikrobielles arzneimittel gegen organismen wirksam zu machen, die normalerweise als resistent dagegen gelten - Google Patents
Formulierung, um ein antimikrobielles arzneimittel gegen organismen wirksam zu machen, die normalerweise als resistent dagegen geltenInfo
- Publication number
- EP1617818A1 EP1617818A1 EP04760446A EP04760446A EP1617818A1 EP 1617818 A1 EP1617818 A1 EP 1617818A1 EP 04760446 A EP04760446 A EP 04760446A EP 04760446 A EP04760446 A EP 04760446A EP 1617818 A1 EP1617818 A1 EP 1617818A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- composition
- agent
- surfactant
- acid
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46635403P | 2003-04-29 | 2003-04-29 | |
PCT/US2004/013268 WO2004096180A1 (en) | 2003-04-29 | 2004-04-29 | Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1617818A1 true EP1617818A1 (de) | 2006-01-25 |
Family
ID=33418369
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP04760446A Withdrawn EP1617818A1 (de) | 2003-04-29 | 2004-04-29 | Formulierung, um ein antimikrobielles arzneimittel gegen organismen wirksam zu machen, die normalerweise als resistent dagegen gelten |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1617818A1 (de) |
JP (1) | JP2006525345A (de) |
KR (1) | KR20060015553A (de) |
CN (1) | CN1794975A (de) |
AU (1) | AU2004234003A1 (de) |
BR (1) | BRPI0409929A (de) |
CA (1) | CA2523151A1 (de) |
MX (1) | MXPA05011607A (de) |
NO (1) | NO20055616L (de) |
WO (1) | WO2004096180A1 (de) |
ZA (1) | ZA200508467B (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100858508B1 (ko) | 2005-12-23 | 2008-09-12 | 주식회사 삼양사 | 아졸계 항진균제를 포함하는 조성물 및 그의 제조방법 |
SG170047A1 (en) * | 2006-05-30 | 2011-04-29 | Elan Pharma Int Ltd | Nanoparticulate posaconazole formulations |
FR2922107B1 (fr) * | 2007-10-10 | 2010-02-26 | Aventis Pharma Sa | Nouvelles compositions a base de taxoides |
US20090238867A1 (en) * | 2007-12-13 | 2009-09-24 | Scott Jenkins | Nanoparticulate Anidulafungin Compositions and Methods for Making the Same |
CN103442728B (zh) * | 2010-12-30 | 2017-04-12 | 抗感染类药物的科学中心 | 用于治疗细菌来源的传染性疾病的抗菌剂 |
CN102085176A (zh) * | 2010-12-31 | 2011-06-08 | 江苏中丹制药有限公司 | 一种纳米级伊曲康唑外用制剂、其制备方法及其用途 |
CN102106832A (zh) * | 2011-02-12 | 2011-06-29 | 华中师范大学 | 酮康唑纳米混悬剂冻干粉及其制备方法 |
JP6962655B2 (ja) * | 2015-07-07 | 2021-11-05 | ライフラフト バイオサイエンシーズ,インコーポレイテッド | 低ナトリウムポロキサマー188製剤および使用方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE259220T1 (de) * | 1998-05-29 | 2004-02-15 | Skyepharma Canada Inc | Gegen hitzeeinwirkung geschützte mikropartikel und verfahren zur terminalen dampfsterilisation derselben |
WO2001021154A2 (en) * | 1999-09-21 | 2001-03-29 | Rtp Pharma Inc. | Surface modified particulate compositions of biologically active substances |
JP4376518B2 (ja) * | 2000-12-22 | 2009-12-02 | バクスター・インターナショナル・インコーポレイテッド | サブミクロン粒子の懸濁物を調製する方法 |
US20030072807A1 (en) * | 2000-12-22 | 2003-04-17 | Wong Joseph Chung-Tak | Solid particulate antifungal compositions for pharmaceutical use |
US7112340B2 (en) * | 2001-10-19 | 2006-09-26 | Baxter International Inc. | Compositions of and method for preparing stable particles in a frozen aqueous matrix |
-
2004
- 2004-04-29 CN CNA2004800116680A patent/CN1794975A/zh active Pending
- 2004-04-29 AU AU2004234003A patent/AU2004234003A1/en not_active Abandoned
- 2004-04-29 JP JP2006513447A patent/JP2006525345A/ja not_active Withdrawn
- 2004-04-29 CA CA002523151A patent/CA2523151A1/en not_active Abandoned
- 2004-04-29 EP EP04760446A patent/EP1617818A1/de not_active Withdrawn
- 2004-04-29 BR BRPI0409929-0A patent/BRPI0409929A/pt not_active IP Right Cessation
- 2004-04-29 MX MXPA05011607A patent/MXPA05011607A/es unknown
- 2004-04-29 WO PCT/US2004/013268 patent/WO2004096180A1/en active Application Filing
- 2004-04-29 KR KR1020057020567A patent/KR20060015553A/ko not_active Application Discontinuation
-
2005
- 2005-10-19 ZA ZA200508467A patent/ZA200508467B/en unknown
- 2005-11-28 NO NO20055616A patent/NO20055616L/no not_active Application Discontinuation
Non-Patent Citations (1)
Title |
---|
See references of WO2004096180A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU2004234003A1 (en) | 2004-11-11 |
ZA200508467B (en) | 2006-09-27 |
WO2004096180A1 (en) | 2004-11-11 |
CN1794975A (zh) | 2006-06-28 |
KR20060015553A (ko) | 2006-02-17 |
BRPI0409929A (pt) | 2006-04-25 |
JP2006525345A (ja) | 2006-11-09 |
NO20055616D0 (no) | 2005-11-28 |
CA2523151A1 (en) | 2004-11-11 |
NO20055616L (no) | 2006-01-25 |
MXPA05011607A (es) | 2005-12-15 |
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AU2002337894B2 (en) | Stable composition comprising particles in a frozen aqueous matrix | |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20051027 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL HR LT LV MK |
|
DAX | Request for extension of the european patent (deleted) | ||
17Q | First examination report despatched |
Effective date: 20070412 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20071023 |