BRPI0409929A - formulação para tornar uma droga antimicrobiana potente contra organismos normalmente considerados serem resistentes à droga - Google Patents
formulação para tornar uma droga antimicrobiana potente contra organismos normalmente considerados serem resistentes à drogaInfo
- Publication number
- BRPI0409929A BRPI0409929A BRPI0409929-0A BRPI0409929A BRPI0409929A BR PI0409929 A BRPI0409929 A BR PI0409929A BR PI0409929 A BRPI0409929 A BR PI0409929A BR PI0409929 A BRPI0409929 A BR PI0409929A
- Authority
- BR
- Brazil
- Prior art keywords
- drug
- resistant
- agent
- normally considered
- formulation
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 239000004599 antimicrobial Substances 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 3
- 238000009472 formulation Methods 0.000 title abstract 2
- 230000003389 potentiating effect Effects 0.000 title abstract 2
- 239000002245 particle Substances 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 239000004094 surface-active agent Substances 0.000 abstract 2
- 229940093740 amino acid and derivative Drugs 0.000 abstract 1
- 230000003515 anti-microbian Effects 0.000 abstract 1
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 239000002563 ionic surfactant Substances 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
"FORMULAçãO PARA TORNAR UMA DROGA ANTI-MICROBIANA POTENTE CONTRA ORGANISMOS NORMALMENTE CONSIDERADOS SEREM RESISTENTES à DROGA". A presente invenção refere-se a composições de partículas de tamanho submícron a mícron de agentes antimicrobianos. Mais particularmente a invenção refere-se a uma composição de um agente antimicrobiano que torna o agente potente contra organismos normalmente considerados serem resistentes ao agente. A composição compreende uma suspensão aquosa de partículas de tamanho submícron a mícron contendo o agente revestidas com pelo menos um tensoativo selecionado do grupo consistindo em: tensoativos iónicos, tensoativos não-iónicos, tensoativos derivados biologicamente, e aminoácidos e seus derivados. As partículas têm um tamanho de partícula médio de volume pesado de menos que 5 <109>m como medido por difratometria de laser.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46635403P | 2003-04-29 | 2003-04-29 | |
PCT/US2004/013268 WO2004096180A1 (en) | 2003-04-29 | 2004-04-29 | Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0409929A true BRPI0409929A (pt) | 2006-04-25 |
Family
ID=33418369
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0409929-0A BRPI0409929A (pt) | 2003-04-29 | 2004-04-29 | formulação para tornar uma droga antimicrobiana potente contra organismos normalmente considerados serem resistentes à droga |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1617818A1 (pt) |
JP (1) | JP2006525345A (pt) |
KR (1) | KR20060015553A (pt) |
CN (1) | CN1794975A (pt) |
AU (1) | AU2004234003A1 (pt) |
BR (1) | BRPI0409929A (pt) |
CA (1) | CA2523151A1 (pt) |
MX (1) | MXPA05011607A (pt) |
NO (1) | NO20055616L (pt) |
WO (1) | WO2004096180A1 (pt) |
ZA (1) | ZA200508467B (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100858508B1 (ko) | 2005-12-23 | 2008-09-12 | 주식회사 삼양사 | 아졸계 항진균제를 포함하는 조성물 및 그의 제조방법 |
JP2009538927A (ja) * | 2006-05-30 | 2009-11-12 | エラン ファーマ インターナショナル,リミティド | ナノ粒子状のポサコナゾール製剤 |
FR2922107B1 (fr) * | 2007-10-10 | 2010-02-26 | Aventis Pharma Sa | Nouvelles compositions a base de taxoides |
US20090238867A1 (en) * | 2007-12-13 | 2009-09-24 | Scott Jenkins | Nanoparticulate Anidulafungin Compositions and Methods for Making the Same |
DE11853027T1 (de) * | 2010-12-30 | 2014-09-11 | Respublikanskoe Gosudarstvennoe Predpriyatie "Nauchnyj Centr Protivoinfekcionnyh | Antibakterielles mittel zur behandlung von infektionskrankheiten bakteriellen ursprungs |
CN102085176A (zh) * | 2010-12-31 | 2011-06-08 | 江苏中丹制药有限公司 | 一种纳米级伊曲康唑外用制剂、其制备方法及其用途 |
CN102106832A (zh) * | 2011-02-12 | 2011-06-29 | 华中师范大学 | 酮康唑纳米混悬剂冻干粉及其制备方法 |
EP3319608A4 (en) * | 2015-07-07 | 2019-04-03 | LifeRaft Biosciences, Inc. | POLOXAMER 188 FORMULATIONS WITH REDUCED SODIUM AND METHOD OF USE |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2333648C (en) * | 1998-05-29 | 2008-10-21 | Rtp Pharma Inc. | Thermoprotected microparticle compositions and process for terminal steam sterilization thereof |
DE60020382T2 (de) * | 1999-09-21 | 2006-01-26 | Skyepharma Canada Inc., Verdun | Oberflächenmodifizierte teilchenförmige zusammensetzungen biologisch aktiver stoffe |
US20030072807A1 (en) * | 2000-12-22 | 2003-04-17 | Wong Joseph Chung-Tak | Solid particulate antifungal compositions for pharmaceutical use |
DK1347747T3 (da) * | 2000-12-22 | 2006-04-10 | Baxter Int | Fremgangsmåde til behandling af submikropartikelsuspensioner af farmaceutiske midler |
US7112340B2 (en) * | 2001-10-19 | 2006-09-26 | Baxter International Inc. | Compositions of and method for preparing stable particles in a frozen aqueous matrix |
-
2004
- 2004-04-29 KR KR1020057020567A patent/KR20060015553A/ko not_active Application Discontinuation
- 2004-04-29 EP EP04760446A patent/EP1617818A1/en not_active Withdrawn
- 2004-04-29 CA CA002523151A patent/CA2523151A1/en not_active Abandoned
- 2004-04-29 WO PCT/US2004/013268 patent/WO2004096180A1/en active Application Filing
- 2004-04-29 MX MXPA05011607A patent/MXPA05011607A/es unknown
- 2004-04-29 BR BRPI0409929-0A patent/BRPI0409929A/pt not_active IP Right Cessation
- 2004-04-29 JP JP2006513447A patent/JP2006525345A/ja not_active Withdrawn
- 2004-04-29 AU AU2004234003A patent/AU2004234003A1/en not_active Abandoned
- 2004-04-29 CN CNA2004800116680A patent/CN1794975A/zh active Pending
-
2005
- 2005-10-19 ZA ZA200508467A patent/ZA200508467B/en unknown
- 2005-11-28 NO NO20055616A patent/NO20055616L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2523151A1 (en) | 2004-11-11 |
WO2004096180A1 (en) | 2004-11-11 |
MXPA05011607A (es) | 2005-12-15 |
KR20060015553A (ko) | 2006-02-17 |
NO20055616L (no) | 2006-01-25 |
ZA200508467B (en) | 2006-09-27 |
EP1617818A1 (en) | 2006-01-25 |
AU2004234003A1 (en) | 2004-11-11 |
JP2006525345A (ja) | 2006-11-09 |
CN1794975A (zh) | 2006-06-28 |
NO20055616D0 (no) | 2005-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011. |