EP1515982A2 - Zusammensetzungen und verfahren zur therapie und diagnose von prostatakrebs - Google Patents

Zusammensetzungen und verfahren zur therapie und diagnose von prostatakrebs

Info

Publication number
EP1515982A2
EP1515982A2 EP02725984A EP02725984A EP1515982A2 EP 1515982 A2 EP1515982 A2 EP 1515982A2 EP 02725984 A EP02725984 A EP 02725984A EP 02725984 A EP02725984 A EP 02725984A EP 1515982 A2 EP1515982 A2 EP 1515982A2
Authority
EP
European Patent Office
Prior art keywords
seq
sequence
cdna sequence
polypeptide
sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02725984A
Other languages
English (en)
French (fr)
Other versions
EP1515982A4 (de
Inventor
Jiangchun Xu
Davin C. Dillon
Jennifer L. Mitcham
Susan L. Harlocker
Yuqiu Jiang
Robert A. Henderson
Michael D. Kalos
Gary R. Fanger
Marc W. Retter
John A. Stolk
Craig H. Day
Thomas S. Vedvick
Darrick Carter
Samuel X. Li
Aijun Wang
Yasir A. W. Skeiky
William T. Hepler
John Hural
Patricia D. Mcneill
Raymond L. Carlota Houghton
Carlota Vinals Y De Bassols
Teresa M. Foy
Yoshihiro Watanabe
Ta Deng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corixa Corp
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/895,814 external-priority patent/US20020193296A1/en
Priority claimed from US10/012,896 external-priority patent/US6943236B2/en
Application filed by Corixa Corp filed Critical Corixa Corp
Priority to EP08011769A priority Critical patent/EP1988097A1/de
Publication of EP1515982A2 publication Critical patent/EP1515982A2/de
Publication of EP1515982A4 publication Critical patent/EP1515982A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069Reproductive system, e.g. ovaria, uterus, testes, prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/461Cellular immunotherapy characterised by the cell type used
    • A61K39/4611T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/463Cellular immunotherapy characterised by recombinant expression
    • A61K39/4632T-cell receptors [TCR]; antibody T-cell receptor constructs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/46Cellular immunotherapy
    • A61K39/464Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643Vertebrate antigens
    • A61K39/4644Cancer antigens
    • A61K39/464493Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; Prostatic acid phosphatase [PAP]; Prostate-specific G-protein-coupled receptor [PSGR]
    • A61K39/464494Prostate specific antigen [PSA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP02725984A 2001-05-09 2002-05-09 Zusammensetzungen und verfahren zur therapie und diagnose von prostatakrebs Withdrawn EP1515982A4 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP08011769A EP1988097A1 (de) 2001-05-09 2002-05-09 Zusammensetzungen und Verfahren zur Behandlung und Diagnose von Prostatakrebs

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US85291101A 2001-05-09 2001-05-09
US852911 2001-05-09
US895814 2001-06-29
US09/895,814 US20020193296A1 (en) 1997-02-25 2001-06-29 Compositions and methods for the therapy and diagnosis of prostate cancer
US12896 2001-12-10
US10/012,896 US6943236B2 (en) 1997-02-25 2001-12-10 Compositions and methods for the therapy and diagnosis of prostate cancer
PCT/US2002/014753 WO2002089747A2 (en) 2001-05-09 2002-05-09 Compositions and methods for the therapy and diagnosis of prostate cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP08011769A Division EP1988097A1 (de) 2001-05-09 2002-05-09 Zusammensetzungen und Verfahren zur Behandlung und Diagnose von Prostatakrebs

Publications (2)

Publication Number Publication Date
EP1515982A2 true EP1515982A2 (de) 2005-03-23
EP1515982A4 EP1515982A4 (de) 2005-10-26

Family

ID=27359724

Family Applications (2)

Application Number Title Priority Date Filing Date
EP08011769A Withdrawn EP1988097A1 (de) 2001-05-09 2002-05-09 Zusammensetzungen und Verfahren zur Behandlung und Diagnose von Prostatakrebs
EP02725984A Withdrawn EP1515982A4 (de) 2001-05-09 2002-05-09 Zusammensetzungen und verfahren zur therapie und diagnose von prostatakrebs

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP08011769A Withdrawn EP1988097A1 (de) 2001-05-09 2002-05-09 Zusammensetzungen und Verfahren zur Behandlung und Diagnose von Prostatakrebs

Country Status (4)

Country Link
EP (2) EP1988097A1 (de)
JP (1) JP2005504513A (de)
CA (1) CA2446788A1 (de)
WO (1) WO2002089747A2 (de)

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US7244827B2 (en) 2000-04-12 2007-07-17 Agensys, Inc. Nucleic acid and corresponding protein entitled 24P4C12 useful in treatment and detection of cancer
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US6790631B1 (en) 1999-10-05 2004-09-14 Agensys, Inc. G protein-coupled receptor up-regulated in prostate cancer and uses thereof
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