EP1491621B2 - Granules d'alpha-oléfine et alpha-oléfine-celluloses, comme désintégrants - Google Patents
Granules d'alpha-oléfine et alpha-oléfine-celluloses, comme désintégrants Download PDFInfo
- Publication number
- EP1491621B2 EP1491621B2 EP03014785.4A EP03014785A EP1491621B2 EP 1491621 B2 EP1491621 B2 EP 1491621B2 EP 03014785 A EP03014785 A EP 03014785A EP 1491621 B2 EP1491621 B2 EP 1491621B2
- Authority
- EP
- European Patent Office
- Prior art keywords
- weight
- parts
- cellulose
- acid
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008187 granular material Substances 0.000 title claims abstract description 66
- 229920002678 cellulose Polymers 0.000 title claims description 55
- 239000001913 cellulose Substances 0.000 title claims description 49
- 239000004711 α-olefin Substances 0.000 title claims description 16
- 239000007884 disintegrant Substances 0.000 title description 45
- 229920000642 polymer Polymers 0.000 claims abstract description 45
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 21
- 238000004140 cleaning Methods 0.000 claims abstract description 15
- 229910019142 PO4 Inorganic materials 0.000 claims abstract description 8
- 239000010452 phosphate Substances 0.000 claims abstract description 8
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims abstract description 6
- 239000000178 monomer Substances 0.000 claims abstract description 5
- 239000007844 bleaching agent Substances 0.000 claims description 36
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 34
- 229920001577 copolymer Polymers 0.000 claims description 31
- 239000002253 acid Substances 0.000 claims description 24
- 239000004094 surface-active agent Substances 0.000 claims description 21
- 239000012190 activator Substances 0.000 claims description 16
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Natural products OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 16
- 239000000463 material Substances 0.000 claims description 15
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid group Chemical group C(\C=C/C(=O)O)(=O)O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims description 11
- 239000000470 constituent Substances 0.000 claims description 10
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims description 6
- 239000000654 additive Substances 0.000 claims description 6
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 4
- 229920000388 Polyphosphate Polymers 0.000 claims description 4
- 150000002978 peroxides Chemical class 0.000 claims description 4
- 239000001205 polyphosphate Substances 0.000 claims description 4
- 235000011176 polyphosphates Nutrition 0.000 claims description 4
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims description 3
- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 claims description 3
- PXRKCOCTEMYUEG-UHFFFAOYSA-N 5-aminoisoindole-1,3-dione Chemical compound NC1=CC=C2C(=O)NC(=O)C2=C1 PXRKCOCTEMYUEG-UHFFFAOYSA-N 0.000 claims 2
- 239000004615 ingredient Substances 0.000 abstract description 15
- 150000001336 alkenes Chemical class 0.000 abstract description 2
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 description 85
- 239000003826 tablet Substances 0.000 description 67
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 59
- 235000010980 cellulose Nutrition 0.000 description 50
- 239000003599 detergent Substances 0.000 description 50
- -1 hydroxypropyl Chemical group 0.000 description 41
- 239000002736 nonionic surfactant Substances 0.000 description 41
- 108091005804 Peptidases Proteins 0.000 description 32
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 29
- 229910052757 nitrogen Inorganic materials 0.000 description 29
- 102000004190 Enzymes Human genes 0.000 description 27
- 108090000790 Enzymes Proteins 0.000 description 27
- 239000004365 Protease Substances 0.000 description 27
- 229940088598 enzyme Drugs 0.000 description 27
- 108010065511 Amylases Proteins 0.000 description 25
- 102000013142 Amylases Human genes 0.000 description 25
- 125000004432 carbon atom Chemical group C* 0.000 description 24
- 238000009472 formulation Methods 0.000 description 24
- 235000019419 proteases Nutrition 0.000 description 24
- 235000019418 amylase Nutrition 0.000 description 23
- 239000004382 Amylase Substances 0.000 description 21
- 108090001060 Lipase Proteins 0.000 description 21
- 102000004882 Lipase Human genes 0.000 description 21
- 229920002472 Starch Polymers 0.000 description 19
- 239000002360 explosive Substances 0.000 description 19
- 235000019698 starch Nutrition 0.000 description 19
- 239000004367 Lipase Substances 0.000 description 18
- 235000019421 lipase Nutrition 0.000 description 18
- 150000003839 salts Chemical class 0.000 description 18
- 230000000694 effects Effects 0.000 description 16
- 150000001875 compounds Chemical class 0.000 description 15
- 235000014113 dietary fatty acids Nutrition 0.000 description 15
- 239000000194 fatty acid Substances 0.000 description 15
- 229930195729 fatty acid Natural products 0.000 description 15
- 150000002191 fatty alcohols Chemical class 0.000 description 15
- 239000011976 maleic acid Substances 0.000 description 15
- 238000004851 dishwashing Methods 0.000 description 14
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 12
- 238000000465 moulding Methods 0.000 description 12
- 150000001298 alcohols Chemical class 0.000 description 11
- 150000004665 fatty acids Chemical class 0.000 description 11
- 239000003205 fragrance Substances 0.000 description 11
- 239000002245 particle Substances 0.000 description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 10
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 10
- 238000000034 method Methods 0.000 description 10
- 239000000047 product Substances 0.000 description 10
- 150000003254 radicals Chemical class 0.000 description 10
- 229940032147 starch Drugs 0.000 description 10
- 239000008107 starch Substances 0.000 description 10
- 239000000126 substance Substances 0.000 description 10
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 10
- 150000007513 acids Chemical class 0.000 description 9
- 238000005260 corrosion Methods 0.000 description 9
- 239000002304 perfume Substances 0.000 description 9
- 239000011734 sodium Substances 0.000 description 9
- 235000000346 sugar Nutrition 0.000 description 9
- 229920000881 Modified starch Polymers 0.000 description 8
- 229920002125 Sokalan® Polymers 0.000 description 8
- BGRWYDHXPHLNKA-UHFFFAOYSA-N Tetraacetylethylenediamine Chemical compound CC(=O)N(C(C)=O)CCN(C(C)=O)C(C)=O BGRWYDHXPHLNKA-UHFFFAOYSA-N 0.000 description 8
- 230000007797 corrosion Effects 0.000 description 8
- 235000019426 modified starch Nutrition 0.000 description 8
- 230000008569 process Effects 0.000 description 8
- 238000003860 storage Methods 0.000 description 8
- 239000002202 Polyethylene glycol Substances 0.000 description 7
- 239000003945 anionic surfactant Substances 0.000 description 7
- 238000001035 drying Methods 0.000 description 7
- 229920001223 polyethylene glycol Polymers 0.000 description 7
- 239000000344 soap Substances 0.000 description 7
- 229920001131 Pulp (paper) Polymers 0.000 description 6
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 6
- ULUAUXLGCMPNKK-UHFFFAOYSA-N Sulfobutanedioic acid Chemical class OC(=O)CC(C(O)=O)S(O)(=O)=O ULUAUXLGCMPNKK-UHFFFAOYSA-N 0.000 description 6
- 238000009826 distribution Methods 0.000 description 6
- 230000002366 lipolytic effect Effects 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 238000002844 melting Methods 0.000 description 6
- 230000008018 melting Effects 0.000 description 6
- 239000003921 oil Substances 0.000 description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 5
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 5
- 238000010521 absorption reaction Methods 0.000 description 5
- 238000005056 compaction Methods 0.000 description 5
- 150000002148 esters Chemical class 0.000 description 5
- 239000011521 glass Substances 0.000 description 5
- 150000004676 glycans Chemical class 0.000 description 5
- 229920001451 polypropylene glycol Polymers 0.000 description 5
- 229910052708 sodium Inorganic materials 0.000 description 5
- 235000019832 sodium triphosphate Nutrition 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 239000003760 tallow Substances 0.000 description 5
- 238000005406 washing Methods 0.000 description 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 4
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 4
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 4
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 4
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical group CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 description 4
- 239000003513 alkali Substances 0.000 description 4
- 125000000217 alkyl group Chemical group 0.000 description 4
- 150000001412 amines Chemical class 0.000 description 4
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 4
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 4
- 239000001768 carboxy methyl cellulose Substances 0.000 description 4
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 4
- 239000003054 catalyst Substances 0.000 description 4
- 239000012459 cleaning agent Substances 0.000 description 4
- 239000013256 coordination polymer Substances 0.000 description 4
- DIOQZVSQGTUSAI-UHFFFAOYSA-N decane Chemical compound CCCCCCCCCC DIOQZVSQGTUSAI-UHFFFAOYSA-N 0.000 description 4
- 238000004090 dissolution Methods 0.000 description 4
- SNRUBQQJIBEYMU-UHFFFAOYSA-N dodecane Chemical compound CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 4
- 239000003112 inhibitor Substances 0.000 description 4
- 229920001282 polysaccharide Polymers 0.000 description 4
- 239000005017 polysaccharide Substances 0.000 description 4
- 229920006395 saturated elastomer Polymers 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 150000003852 triazoles Chemical class 0.000 description 4
- 238000005550 wet granulation Methods 0.000 description 4
- 244000060011 Cocos nucifera Species 0.000 description 3
- 235000013162 Cocos nucifera Nutrition 0.000 description 3
- IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 102000004157 Hydrolases Human genes 0.000 description 3
- 108090000604 Hydrolases Proteins 0.000 description 3
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 3
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 3
- 102000035195 Peptidases Human genes 0.000 description 3
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical class OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 description 3
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 3
- UAOKXEHOENRFMP-ZJIFWQFVSA-N [(2r,3r,4s,5r)-2,3,4,5-tetraacetyloxy-6-oxohexyl] acetate Chemical compound CC(=O)OC[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)C=O UAOKXEHOENRFMP-ZJIFWQFVSA-N 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 3
- 238000005422 blasting Methods 0.000 description 3
- 229920001400 block copolymer Polymers 0.000 description 3
- 150000001244 carboxylic acid anhydrides Chemical class 0.000 description 3
- 229920003086 cellulose ether Polymers 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 230000006835 compression Effects 0.000 description 3
- 239000002270 dispersing agent Substances 0.000 description 3
- 239000000975 dye Substances 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 238000005469 granulation Methods 0.000 description 3
- 230000003179 granulation Effects 0.000 description 3
- 229930195733 hydrocarbon Natural products 0.000 description 3
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 3
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 3
- 229920000609 methyl cellulose Polymers 0.000 description 3
- 235000010981 methylcellulose Nutrition 0.000 description 3
- 239000001923 methylcellulose Substances 0.000 description 3
- 229940016286 microcrystalline cellulose Drugs 0.000 description 3
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 3
- 239000008108 microcrystalline cellulose Substances 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 150000004965 peroxy acids Chemical class 0.000 description 3
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 description 3
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 3
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 238000003825 pressing Methods 0.000 description 3
- 229910052709 silver Inorganic materials 0.000 description 3
- 239000004332 silver Substances 0.000 description 3
- 229910000029 sodium carbonate Inorganic materials 0.000 description 3
- YYCZTGHZVYEDNT-UHFFFAOYSA-N (1,3-diacetamido-1,3-dioxopropan-2-yl) acetate Chemical compound CC(=O)NC(=O)C(OC(C)=O)C(=O)NC(C)=O YYCZTGHZVYEDNT-UHFFFAOYSA-N 0.000 description 2
- RKHMZKDESOMZLE-UHFFFAOYSA-N (1,3-diacetyl-5-acetyloxyimidazolidin-4-yl) acetate Chemical compound CC(=O)OC1C(OC(C)=O)N(C(C)=O)CN1C(C)=O RKHMZKDESOMZLE-UHFFFAOYSA-N 0.000 description 2
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 2
- HUPQMDDKEZELTH-UHFFFAOYSA-N 1,3-diacetyl-5,5-dimethylimidazolidine-2,4-dione Chemical compound CC(=O)N1C(=O)N(C(C)=O)C(C)(C)C1=O HUPQMDDKEZELTH-UHFFFAOYSA-N 0.000 description 2
- CBBKKVPJPRZOCM-UHFFFAOYSA-N 1,4-diacetylpiperazine-2,5-dione Chemical compound CC(=O)N1CC(=O)N(C(C)=O)CC1=O CBBKKVPJPRZOCM-UHFFFAOYSA-N 0.000 description 2
- LYPVKWMHGFMDPD-UHFFFAOYSA-N 1,5-diacetyl-1,3,5-triazinane-2,4-dione Chemical compound CC(=O)N1CN(C(C)=O)C(=O)NC1=O LYPVKWMHGFMDPD-UHFFFAOYSA-N 0.000 description 2
- YBAYHPZEWVQQIJ-UHFFFAOYSA-N 1-octanoylazepan-2-one Chemical compound CCCCCCCC(=O)N1CCCCCC1=O YBAYHPZEWVQQIJ-UHFFFAOYSA-N 0.000 description 2
- WRMNZCZEMHIOCP-UHFFFAOYSA-N 2-phenylethanol Chemical compound OCCC1=CC=CC=C1 WRMNZCZEMHIOCP-UHFFFAOYSA-N 0.000 description 2
- XSVSPKKXQGNHMD-UHFFFAOYSA-N 5-bromo-3-methyl-1,2-thiazole Chemical compound CC=1C=C(Br)SN=1 XSVSPKKXQGNHMD-UHFFFAOYSA-N 0.000 description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 2
- ZCTQGTTXIYCGGC-UHFFFAOYSA-N Benzyl salicylate Chemical compound OC1=CC=CC=C1C(=O)OCC1=CC=CC=C1 ZCTQGTTXIYCGGC-UHFFFAOYSA-N 0.000 description 2
- UYWQUFXKFGHYNT-UHFFFAOYSA-N Benzylformate Chemical compound O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 description 2
- 101100065878 Caenorhabditis elegans sec-10 gene Proteins 0.000 description 2
- 101100172892 Caenorhabditis elegans sec-8 gene Proteins 0.000 description 2
- 229920003043 Cellulose fiber Polymers 0.000 description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 2
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 2
- 229930091371 Fructose Natural products 0.000 description 2
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 2
- 239000005715 Fructose Substances 0.000 description 2
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 description 2
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 2
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
- BTJXBZZBBNNTOV-UHFFFAOYSA-N Linalyl benzoate Chemical compound CC(C)=CCCC(C)(C=C)OC(=O)C1=CC=CC=C1 BTJXBZZBBNNTOV-UHFFFAOYSA-N 0.000 description 2
- 239000004368 Modified starch Substances 0.000 description 2
- 102000004316 Oxidoreductases Human genes 0.000 description 2
- 108090000854 Oxidoreductases Proteins 0.000 description 2
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 description 2
- LGRFSURHDFAFJT-UHFFFAOYSA-N Phthalic anhydride Natural products C1=CC=C2C(=O)OC(=O)C2=C1 LGRFSURHDFAFJT-UHFFFAOYSA-N 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 2
- ZJCCRDAZUWHFQH-UHFFFAOYSA-N Trimethylolpropane Chemical compound CCC(CO)(CO)CO ZJCCRDAZUWHFQH-UHFFFAOYSA-N 0.000 description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 2
- 230000010933 acylation Effects 0.000 description 2
- 238000005917 acylation reaction Methods 0.000 description 2
- 150000001299 aldehydes Chemical class 0.000 description 2
- 229920000615 alginic acid Polymers 0.000 description 2
- 235000010443 alginic acid Nutrition 0.000 description 2
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 description 2
- 229910000288 alkali metal carbonate Inorganic materials 0.000 description 2
- 150000008041 alkali metal carbonates Chemical class 0.000 description 2
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 2
- 125000002947 alkylene group Chemical group 0.000 description 2
- 108090000637 alpha-Amylases Proteins 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- 229910021529 ammonia Inorganic materials 0.000 description 2
- 229940025131 amylases Drugs 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 2
- 150000005840 aryl radicals Chemical class 0.000 description 2
- 239000002585 base Substances 0.000 description 2
- 235000012216 bentonite Nutrition 0.000 description 2
- GGNQRNBDZQJCCN-UHFFFAOYSA-N benzene-1,2,4-triol Chemical compound OC1=CC=C(O)C(O)=C1 GGNQRNBDZQJCCN-UHFFFAOYSA-N 0.000 description 2
- QRUDEWIWKLJBPS-UHFFFAOYSA-N benzotriazole Chemical compound C1=CC=C2N[N][N]C2=C1 QRUDEWIWKLJBPS-UHFFFAOYSA-N 0.000 description 2
- 239000012964 benzotriazole Substances 0.000 description 2
- QUKGYYKBILRGFE-UHFFFAOYSA-N benzyl acetate Chemical compound CC(=O)OCC1=CC=CC=C1 QUKGYYKBILRGFE-UHFFFAOYSA-N 0.000 description 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 2
- 239000011230 binding agent Substances 0.000 description 2
- JHIWVOJDXOSYLW-UHFFFAOYSA-N butyl 2,2-difluorocyclopropane-1-carboxylate Chemical compound CCCCOC(=O)C1CC1(F)F JHIWVOJDXOSYLW-UHFFFAOYSA-N 0.000 description 2
- 150000007942 carboxylates Chemical class 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- YCIMNLLNPGFGHC-UHFFFAOYSA-N catechol Chemical compound OC1=CC=CC=C1O YCIMNLLNPGFGHC-UHFFFAOYSA-N 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- NEHNMFOYXAPHSD-UHFFFAOYSA-N citronellal Chemical compound O=CCC(C)CCC=C(C)C NEHNMFOYXAPHSD-UHFFFAOYSA-N 0.000 description 2
- QMVPMAAFGQKVCJ-UHFFFAOYSA-N citronellol Chemical compound OCCC(C)CCC=C(C)C QMVPMAAFGQKVCJ-UHFFFAOYSA-N 0.000 description 2
- VTIIJXUACCWYHX-UHFFFAOYSA-L disodium;carboxylatooxy carbonate Chemical compound [Na+].[Na+].[O-]C(=O)OOC([O-])=O VTIIJXUACCWYHX-UHFFFAOYSA-L 0.000 description 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical class CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 2
- 150000002170 ethers Chemical class 0.000 description 2
- 238000007046 ethoxylation reaction Methods 0.000 description 2
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 description 2
- 235000019387 fatty acid methyl ester Nutrition 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 238000005187 foaming Methods 0.000 description 2
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- 150000001469 hydantoins Chemical class 0.000 description 2
- 229940042795 hydrazides for tuberculosis treatment Drugs 0.000 description 2
- 150000002430 hydrocarbons Chemical class 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-M hydrogensulfate Chemical compound OS([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-M 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 description 2
- 150000002443 hydroxylamines Chemical class 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- ZFSLODLOARCGLH-UHFFFAOYSA-N isocyanuric acid Chemical compound OC1=NC(O)=NC(O)=N1 ZFSLODLOARCGLH-UHFFFAOYSA-N 0.000 description 2
- 150000002576 ketones Chemical class 0.000 description 2
- 239000008101 lactose Substances 0.000 description 2
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 description 2
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 description 2
- UWKAYLJWKGQEPM-LBPRGKRZSA-N linalyl acetate Chemical compound CC(C)=CCC[C@](C)(C=C)OC(C)=O UWKAYLJWKGQEPM-LBPRGKRZSA-N 0.000 description 2
- 159000000003 magnesium salts Chemical class 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 2
- 235000019341 magnesium sulphate Nutrition 0.000 description 2
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- UJPCOKISUIXFFR-UHFFFAOYSA-N n-acetyl-n-(4-methylphenyl)acetamide Chemical compound CC(=O)N(C(C)=O)C1=CC=C(C)C=C1 UJPCOKISUIXFFR-UHFFFAOYSA-N 0.000 description 2
- KBDYPDHUODKDRK-UHFFFAOYSA-N n-acetyl-n-phenylacetamide Chemical compound CC(=O)N(C(C)=O)C1=CC=CC=C1 KBDYPDHUODKDRK-UHFFFAOYSA-N 0.000 description 2
- DDNVNUWFESEAHN-UHFFFAOYSA-N n-methyl-n-methylsulfonylacetamide Chemical compound CC(=O)N(C)S(C)(=O)=O DDNVNUWFESEAHN-UHFFFAOYSA-N 0.000 description 2
- 229940055577 oleyl alcohol Drugs 0.000 description 2
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 2
- 150000002894 organic compounds Chemical class 0.000 description 2
- 150000004967 organic peroxy acids Chemical class 0.000 description 2
- 150000002923 oximes Chemical class 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- MDHYEMXUFSJLGV-UHFFFAOYSA-N phenethyl acetate Chemical compound CC(=O)OCCC1=CC=CC=C1 MDHYEMXUFSJLGV-UHFFFAOYSA-N 0.000 description 2
- 229910052615 phyllosilicate Inorganic materials 0.000 description 2
- BXRNXXXXHLBUKK-UHFFFAOYSA-N piperazine-2,5-dione Chemical compound O=C1CNC(=O)CN1 BXRNXXXXHLBUKK-UHFFFAOYSA-N 0.000 description 2
- WQGWDDDVZFFDIG-UHFFFAOYSA-N pyrogallol Chemical compound OC1=CC=CC(O)=C1O WQGWDDDVZFFDIG-UHFFFAOYSA-N 0.000 description 2
- 238000006268 reductive amination reaction Methods 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000012418 sodium perborate tetrahydrate Substances 0.000 description 2
- 229940045872 sodium percarbonate Drugs 0.000 description 2
- 159000000000 sodium salts Chemical class 0.000 description 2
- IBDSNZLUHYKHQP-UHFFFAOYSA-N sodium;3-oxidodioxaborirane;tetrahydrate Chemical compound O.O.O.O.[Na+].[O-]B1OO1 IBDSNZLUHYKHQP-UHFFFAOYSA-N 0.000 description 2
- 239000000600 sorbitol Substances 0.000 description 2
- 235000010356 sorbitol Nutrition 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 125000001424 substituent group Chemical group 0.000 description 2
- RUVINXPYWBROJD-ONEGZZNKSA-N trans-anethole Chemical compound COC1=CC=C(\C=C\C)C=C1 RUVINXPYWBROJD-ONEGZZNKSA-N 0.000 description 2
- 239000002023 wood Substances 0.000 description 2
- 229910052725 zinc Inorganic materials 0.000 description 2
- 239000011701 zinc Substances 0.000 description 2
- 150000003752 zinc compounds Chemical class 0.000 description 2
- BVUOEDOMUOJKOY-UHFFFAOYSA-N (2,5-dioxopyrrolidin-1-yl) benzoate Chemical compound C=1C=CC=CC=1C(=O)ON1C(=O)CCC1=O BVUOEDOMUOJKOY-UHFFFAOYSA-N 0.000 description 1
- HFVMEOPYDLEHBR-UHFFFAOYSA-N (2-fluorophenyl)-phenylmethanol Chemical compound C=1C=CC=C(F)C=1C(O)C1=CC=CC=C1 HFVMEOPYDLEHBR-UHFFFAOYSA-N 0.000 description 1
- SWMBOMMGMHMOHE-MHLULTLJSA-N (2r,3r,4r,5r)-hexane-1,2,3,4,5,6-hexol;(2r,3r,4r,5s)-hexane-1,2,3,4,5,6-hexol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO SWMBOMMGMHMOHE-MHLULTLJSA-N 0.000 description 1
- NIHKFGMYMWGERR-UHFFFAOYSA-N (3-chlorobenzoyl) 3-chlorobenzoate Chemical compound ClC1=CC=CC(C(=O)OC(=O)C=2C=C(Cl)C=CC=2)=C1 NIHKFGMYMWGERR-UHFFFAOYSA-N 0.000 description 1
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 description 1
- SGCDDNPIWJIMLQ-HVUFBIHRSA-N (3s,4s,5r,6r)-3,4,5-triacetyl-3,4,5,6,7-pentahydroxy-1-phenylnonane-1,2,8-trione Chemical compound CC(=O)C(O)[C@@H](O)[C@](O)(C(C)=O)[C@@](O)(C(C)=O)[C@](O)(C(C)=O)C(=O)C(=O)C1=CC=CC=C1 SGCDDNPIWJIMLQ-HVUFBIHRSA-N 0.000 description 1
- BXGCWTYHXORKAO-UAHLEYORSA-N (4r,5r,6s,7s)-5,6,7-triacetyl-3,4,5,6,7-pentahydroxyhexadecane-2,8,9-trione Chemical compound CCCCCCCC(=O)C(=O)[C@@](O)(C(C)=O)[C@](O)(C(C)=O)[C@@](O)(C(C)=O)[C@H](O)C(O)C(C)=O BXGCWTYHXORKAO-UAHLEYORSA-N 0.000 description 1
- WEFHSZAZNMEWKJ-KEDVMYETSA-N (6Z,8E)-undeca-6,8,10-trien-2-one (6E,8E)-undeca-6,8,10-trien-2-one (6Z,8E)-undeca-6,8,10-trien-3-one (6E,8E)-undeca-6,8,10-trien-3-one (6Z,8E)-undeca-6,8,10-trien-4-one (6E,8E)-undeca-6,8,10-trien-4-one Chemical compound CCCC(=O)C\C=C\C=C\C=C.CCCC(=O)C\C=C/C=C/C=C.CCC(=O)CC\C=C\C=C\C=C.CCC(=O)CC\C=C/C=C/C=C.CC(=O)CCC\C=C\C=C\C=C.CC(=O)CCC\C=C/C=C/C=C WEFHSZAZNMEWKJ-KEDVMYETSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- QMVPMAAFGQKVCJ-SNVBAGLBSA-N (R)-(+)-citronellol Natural products OCC[C@H](C)CCC=C(C)C QMVPMAAFGQKVCJ-SNVBAGLBSA-N 0.000 description 1
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 description 1
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- YYMCVDNIIFNDJK-XFQWXJFMSA-N (z)-1-(3-fluorophenyl)-n-[(z)-(3-fluorophenyl)methylideneamino]methanimine Chemical compound FC1=CC=CC(\C=N/N=C\C=2C=C(F)C=CC=2)=C1 YYMCVDNIIFNDJK-XFQWXJFMSA-N 0.000 description 1
- VAVZXZURPCYUHS-RQOWECAXSA-N (z)-3-(hydrazinecarbonyl)-4-oxopent-2-enoic acid Chemical compound OC(=O)/C=C(C(=O)C)\C(=O)NN VAVZXZURPCYUHS-RQOWECAXSA-N 0.000 description 1
- FIDRAVVQGKNYQK-UHFFFAOYSA-N 1,2,3,4-tetrahydrotriazine Chemical compound C1NNNC=C1 FIDRAVVQGKNYQK-UHFFFAOYSA-N 0.000 description 1
- UDATXMIGEVPXTR-UHFFFAOYSA-N 1,2,4-triazolidine-3,5-dione Chemical compound O=C1NNC(=O)N1 UDATXMIGEVPXTR-UHFFFAOYSA-N 0.000 description 1
- JTZUXKIKHMIVSD-UHFFFAOYSA-N 1-(carbamoylamino)propan-2-ylurea Chemical compound NC(=O)NC(C)CNC(N)=O JTZUXKIKHMIVSD-UHFFFAOYSA-N 0.000 description 1
- WCIQNYOXLZQQMU-UHFFFAOYSA-N 1-Phenylethyl propanoate Chemical compound CCC(=O)OC(C)C1=CC=CC=C1 WCIQNYOXLZQQMU-UHFFFAOYSA-N 0.000 description 1
- FEFQUIPMKBPKAR-UHFFFAOYSA-N 1-benzoylazepan-2-one Chemical compound C=1C=CC=CC=1C(=O)N1CCCCCC1=O FEFQUIPMKBPKAR-UHFFFAOYSA-N 0.000 description 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 1
- NOGFHTGYPKWWRX-UHFFFAOYSA-N 2,2,6,6-tetramethyloxan-4-one Chemical compound CC1(C)CC(=O)CC(C)(C)O1 NOGFHTGYPKWWRX-UHFFFAOYSA-N 0.000 description 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- FLUWAIIVLCVEKF-UHFFFAOYSA-N 2-Methyl-1-phenyl-2-propanyl acetate Chemical compound CC(=O)OC(C)(C)CC1=CC=CC=C1 FLUWAIIVLCVEKF-UHFFFAOYSA-N 0.000 description 1
- MJTPMXWJHPOWGH-UHFFFAOYSA-N 2-Phenoxyethyl isobutyrate Chemical compound CC(C)C(=O)OCCOC1=CC=CC=C1 MJTPMXWJHPOWGH-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- ZJVJPPNOQCMEPI-UHFFFAOYSA-N 2-[ethyl(methyl)amino]-2-phenylacetic acid Chemical compound CCN(C)C(C(O)=O)C1=CC=CC=C1 ZJVJPPNOQCMEPI-UHFFFAOYSA-N 0.000 description 1
- LSMBSSQAHLXMEB-UHFFFAOYSA-N 2-cyclohexyl-1,3,2-dioxazetidin-4-one Chemical compound C1(ON(C2CCCCC2)O1)=O LSMBSSQAHLXMEB-UHFFFAOYSA-N 0.000 description 1
- 125000004398 2-methyl-2-butyl group Chemical group CC(C)(CC)* 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- JSIAIROWMJGMQZ-UHFFFAOYSA-N 2h-triazol-4-amine Chemical class NC1=CNN=N1 JSIAIROWMJGMQZ-UHFFFAOYSA-N 0.000 description 1
- YNJSNEKCXVFDKW-UHFFFAOYSA-N 3-(5-amino-1h-indol-3-yl)-2-azaniumylpropanoate Chemical compound C1=C(N)C=C2C(CC(N)C(O)=O)=CNC2=C1 YNJSNEKCXVFDKW-UHFFFAOYSA-N 0.000 description 1
- UNDXPKDBFOOQFC-UHFFFAOYSA-N 4-[2-nitro-4-(trifluoromethyl)phenyl]morpholine Chemical compound [O-][N+](=O)C1=CC(C(F)(F)F)=CC=C1N1CCOCC1 UNDXPKDBFOOQFC-UHFFFAOYSA-N 0.000 description 1
- MBZRJSQZCBXRGK-UHFFFAOYSA-N 4-tert-Butylcyclohexyl acetate Chemical compound CC(=O)OC1CCC(C(C)(C)C)CC1 MBZRJSQZCBXRGK-UHFFFAOYSA-N 0.000 description 1
- PFPSOZSOSPOAPX-UHFFFAOYSA-N 7-(7-oxoazepane-2-carbonyl)azepan-2-one Chemical compound C1CCCC(=O)NC1C(=O)C1CCCCC(=O)N1 PFPSOZSOSPOAPX-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 241000193422 Bacillus lentus Species 0.000 description 1
- 241000194108 Bacillus licheniformis Species 0.000 description 1
- 244000063299 Bacillus subtilis Species 0.000 description 1
- 235000014469 Bacillus subtilis Nutrition 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- 241000717739 Boswellia sacra Species 0.000 description 1
- JFRUPRQHUBWFEQ-UHFFFAOYSA-N C1(ON(CCC)O1)=O Chemical compound C1(ON(CCC)O1)=O JFRUPRQHUBWFEQ-UHFFFAOYSA-N 0.000 description 1
- 101100172879 Caenorhabditis elegans sec-5 gene Proteins 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 240000007436 Cananga odorata Species 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 240000003538 Chamaemelum nobile Species 0.000 description 1
- 235000007866 Chamaemelum nobile Nutrition 0.000 description 1
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 description 1
- 240000008772 Cistus ladanifer Species 0.000 description 1
- 235000005241 Cistus ladanifer Nutrition 0.000 description 1
- WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 description 1
- 241000207199 Citrus Species 0.000 description 1
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 1
- 244000251987 Coprinus macrorhizus Species 0.000 description 1
- 235000001673 Coprinus macrorhizus Nutrition 0.000 description 1
- 244000303965 Cyamopsis psoralioides Species 0.000 description 1
- 229920000089 Cyclic olefin copolymer Polymers 0.000 description 1
- 229920000858 Cyclodextrin Polymers 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 description 1
- 108090000371 Esterases Proteins 0.000 description 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 description 1
- DBVJJBKOTRCVKF-UHFFFAOYSA-N Etidronic acid Chemical compound OP(=O)(O)C(O)(C)P(O)(O)=O DBVJJBKOTRCVKF-UHFFFAOYSA-N 0.000 description 1
- 239000005770 Eugenol Substances 0.000 description 1
- 241000116713 Ferula gummosa Species 0.000 description 1
- 239000004863 Frankincense Substances 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 239000005792 Geraniol Substances 0.000 description 1
- GLZPCOQZEFWAFX-YFHOEESVSA-N Geraniol Natural products CC(C)=CCC\C(C)=C/CO GLZPCOQZEFWAFX-YFHOEESVSA-N 0.000 description 1
- 241001480714 Humicola insolens Species 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- 229920001612 Hydroxyethyl starch Polymers 0.000 description 1
- 108010028688 Isoamylase Proteins 0.000 description 1
- 235000010254 Jasminum officinale Nutrition 0.000 description 1
- 240000005385 Jasminum sambac Species 0.000 description 1
- 241000721662 Juniperus Species 0.000 description 1
- 239000004869 Labdanum Substances 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- 241000234269 Liliales Species 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 1
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 235000007232 Matricaria chamomilla Nutrition 0.000 description 1
- 244000062730 Melissa officinalis Species 0.000 description 1
- 235000010654 Melissa officinalis Nutrition 0.000 description 1
- 235000006679 Mentha X verticillata Nutrition 0.000 description 1
- 235000002899 Mentha suaveolens Nutrition 0.000 description 1
- 235000001636 Mentha x rotundifolia Nutrition 0.000 description 1
- KWYHDKDOAIKMQN-UHFFFAOYSA-N N,N,N',N'-tetramethylethylenediamine Chemical compound CN(C)CCN(C)C KWYHDKDOAIKMQN-UHFFFAOYSA-N 0.000 description 1
- QISSLHPKTCLLDL-UHFFFAOYSA-N N-Acetylcaprolactam Chemical compound CC(=O)N1CCCCCC1=O QISSLHPKTCLLDL-UHFFFAOYSA-N 0.000 description 1
- QECVIPBZOPUTRD-UHFFFAOYSA-N N=S(=O)=O Chemical class N=S(=O)=O QECVIPBZOPUTRD-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- 108700020962 Peroxidase Proteins 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- JPYHHZQJCSQRJY-UHFFFAOYSA-N Phloroglucinol Natural products CCC=CCC=CCC=CCC=CCCCCC(=O)C1=C(O)C=C(O)C=C1O JPYHHZQJCSQRJY-UHFFFAOYSA-N 0.000 description 1
- 240000008299 Pinus lambertiana Species 0.000 description 1
- 240000002505 Pogostemon cablin Species 0.000 description 1
- 235000011751 Pogostemon cablin Nutrition 0.000 description 1
- 108010059820 Polygalacturonase Proteins 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 description 1
- 229920000297 Rayon Polymers 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- 240000000513 Santalum album Species 0.000 description 1
- 235000008632 Santalum album Nutrition 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- 241000187392 Streptomyces griseus Species 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 235000016639 Syzygium aromaticum Nutrition 0.000 description 1
- 244000223014 Syzygium aromaticum Species 0.000 description 1
- 240000006909 Tilia x europaea Species 0.000 description 1
- 235000011941 Tilia x europaea Nutrition 0.000 description 1
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- 244000284012 Vetiveria zizanioides Species 0.000 description 1
- 235000007769 Vetiveria zizanioides Nutrition 0.000 description 1
- QYKIQEUNHZKYBP-UHFFFAOYSA-N Vinyl ether Chemical class C=COC=C QYKIQEUNHZKYBP-UHFFFAOYSA-N 0.000 description 1
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 description 1
- 239000001083 [(2R,3R,4S,5R)-1,2,4,5-tetraacetyloxy-6-oxohexan-3-yl] acetate Substances 0.000 description 1
- ZYPMNZKYVVSXOJ-YNEHKIRRSA-N [(2r,3s,4r)-2,3,4-triacetyloxy-5-oxopentyl] acetate Chemical compound CC(=O)OC[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)C=O ZYPMNZKYVVSXOJ-YNEHKIRRSA-N 0.000 description 1
- LMETVDMCIJNNKH-UHFFFAOYSA-N [(3,7-Dimethyl-6-octenyl)oxy]acetaldehyde Chemical compound CC(C)=CCCC(C)CCOCC=O LMETVDMCIJNNKH-UHFFFAOYSA-N 0.000 description 1
- 150000001242 acetic acid derivatives Chemical class 0.000 description 1
- SWLWZVHQLWXZTQ-UHFFFAOYSA-N acetonitrile;4-methylmorpholin-4-ium;methyl sulfate Chemical compound CC#N.COS([O-])(=O)=O.C[NH+]1CCOCC1 SWLWZVHQLWXZTQ-UHFFFAOYSA-N 0.000 description 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 description 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 125000002252 acyl group Chemical group 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 238000005054 agglomeration Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 125000001931 aliphatic group Chemical group 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 150000001340 alkali metals Chemical class 0.000 description 1
- 150000004703 alkoxides Chemical class 0.000 description 1
- 150000003973 alkyl amines Chemical class 0.000 description 1
- 125000005263 alkylenediamine group Polymers 0.000 description 1
- 102000004139 alpha-Amylases Human genes 0.000 description 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- QUMXDOLUJCHOAY-UHFFFAOYSA-N alpha-methylbenzyl acetate Natural products CC(=O)OC(C)C1=CC=CC=C1 QUMXDOLUJCHOAY-UHFFFAOYSA-N 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- DFNYGALUNNFWKJ-UHFFFAOYSA-N aminoacetonitrile Chemical compound NCC#N DFNYGALUNNFWKJ-UHFFFAOYSA-N 0.000 description 1
- 150000003863 ammonium salts Chemical class 0.000 description 1
- 239000002280 amphoteric surfactant Substances 0.000 description 1
- 229940011037 anethole Drugs 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 229910052785 arsenic Inorganic materials 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000002238 attenuated effect Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 239000000440 bentonite Substances 0.000 description 1
- 229910000278 bentonite Inorganic materials 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- 150000001565 benzotriazoles Chemical class 0.000 description 1
- 229940007550 benzyl acetate Drugs 0.000 description 1
- JGQFVRIQXUFPAH-UHFFFAOYSA-N beta-citronellol Natural products OCCC(C)CCCC(C)=C JGQFVRIQXUFPAH-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- 230000001588 bifunctional effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000004061 bleaching Methods 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 150000001642 boronic acid derivatives Chemical class 0.000 description 1
- FZJUFJKVIYFBSY-UHFFFAOYSA-N bourgeonal Chemical compound CC(C)(C)C1=CC=C(CCC=O)C=C1 FZJUFJKVIYFBSY-UHFFFAOYSA-N 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 150000001733 carboxylic acid esters Chemical class 0.000 description 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 239000003518 caustics Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 235000017803 cinnamon Nutrition 0.000 description 1
- 229940043350 citral Drugs 0.000 description 1
- 150000001860 citric acid derivatives Chemical class 0.000 description 1
- 229930003633 citronellal Natural products 0.000 description 1
- 235000000983 citronellal Nutrition 0.000 description 1
- 235000000484 citronellol Nutrition 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- 239000004927 clay Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229920006037 cross link polymer Polymers 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 108010005400 cutinase Proteins 0.000 description 1
- 150000007973 cyanuric acids Chemical class 0.000 description 1
- 229940019836 cyclamen aldehyde Drugs 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 229940097362 cyclodextrins Drugs 0.000 description 1
- 238000013016 damping Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 238000000280 densification Methods 0.000 description 1
- 150000004985 diamines Chemical class 0.000 description 1
- 150000005690 diesters Chemical class 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 229940095104 dimethyl benzyl carbinyl acetate Drugs 0.000 description 1
- 235000011180 diphosphates Nutrition 0.000 description 1
- 150000002016 disaccharides Chemical class 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 239000008393 encapsulating agent Substances 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 125000001033 ether group Chemical group 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 229960002217 eugenol Drugs 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 108010093305 exopolygalacturonase Proteins 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 239000004864 galbanum Substances 0.000 description 1
- 229940074391 gallic acid Drugs 0.000 description 1
- 235000004515 gallic acid Nutrition 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- WTEVQBCEXWBHNA-JXMROGBWSA-N geranial Chemical compound CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 description 1
- 229940113087 geraniol Drugs 0.000 description 1
- 229940050410 gluconate Drugs 0.000 description 1
- 125000001046 glycoluril group Chemical group [H]C12N(*)C(=O)N(*)C1([H])N(*)C(=O)N2* 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 125000003147 glycosyl group Chemical group 0.000 description 1
- 229920000578 graft copolymer Polymers 0.000 description 1
- 159000000011 group IA salts Chemical class 0.000 description 1
- 229940005740 hexametaphosphate Drugs 0.000 description 1
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical compound O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- WPFVBOQKRVRMJB-UHFFFAOYSA-N hydroxycitronellal Chemical compound O=CCC(C)CCCC(C)(C)O WPFVBOQKRVRMJB-UHFFFAOYSA-N 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 229940050526 hydroxyethylstarch Drugs 0.000 description 1
- 150000002466 imines Chemical class 0.000 description 1
- 150000004966 inorganic peroxy acids Chemical class 0.000 description 1
- 229910003480 inorganic solid Inorganic materials 0.000 description 1
- 239000003456 ion exchange resin Substances 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 150000002531 isophthalic acids Chemical class 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 229910052746 lanthanum Inorganic materials 0.000 description 1
- FZLIPJUXYLNCLC-UHFFFAOYSA-N lanthanum atom Chemical compound [La] FZLIPJUXYLNCLC-UHFFFAOYSA-N 0.000 description 1
- SDQFDHOLCGWZPU-UHFFFAOYSA-N lilial Chemical compound O=CC(C)CC1=CC=C(C(C)(C)C)C=C1 SDQFDHOLCGWZPU-UHFFFAOYSA-N 0.000 description 1
- 239000004571 lime Substances 0.000 description 1
- 235000001510 limonene Nutrition 0.000 description 1
- 229940087305 limonene Drugs 0.000 description 1
- 229930007744 linalool Natural products 0.000 description 1
- UWKAYLJWKGQEPM-UHFFFAOYSA-N linalool acetate Natural products CC(C)=CCCC(C)(C=C)OC(C)=O UWKAYLJWKGQEPM-UHFFFAOYSA-N 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 239000000391 magnesium silicate Substances 0.000 description 1
- 235000012243 magnesium silicates Nutrition 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- WRIRWRKPLXCTFD-UHFFFAOYSA-N malonamide Chemical class NC(=O)CC(N)=O WRIRWRKPLXCTFD-UHFFFAOYSA-N 0.000 description 1
- 150000002696 manganese Chemical class 0.000 description 1
- 229910052748 manganese Inorganic materials 0.000 description 1
- 239000011572 manganese Substances 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910044991 metal oxide Inorganic materials 0.000 description 1
- 150000004706 metal oxides Chemical class 0.000 description 1
- 125000005341 metaphosphate group Chemical group 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- ZCYXXKJEDCHMGH-UHFFFAOYSA-N nonane Chemical compound CCCC[CH]CCCC ZCYXXKJEDCHMGH-UHFFFAOYSA-N 0.000 description 1
- SXLLDUPXUVRMEE-UHFFFAOYSA-N nonanediperoxoic acid Chemical compound OOC(=O)CCCCCCCC(=O)OO SXLLDUPXUVRMEE-UHFFFAOYSA-N 0.000 description 1
- 125000001402 nonanoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- BKIMMITUMNQMOS-UHFFFAOYSA-N normal nonane Natural products CCCCCCCCC BKIMMITUMNQMOS-UHFFFAOYSA-N 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- TVMXDCGIABBOFY-UHFFFAOYSA-N octane Chemical compound CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 description 1
- 125000002801 octanoyl group Chemical group C(CCCCCCC)(=O)* 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 238000006384 oligomerization reaction Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 150000007530 organic bases Chemical class 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- RUVINXPYWBROJD-UHFFFAOYSA-N para-methoxyphenyl Natural products COC1=CC=C(C=CC)C=C1 RUVINXPYWBROJD-UHFFFAOYSA-N 0.000 description 1
- 235000011837 pasties Nutrition 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- HWGNBUXHKFFFIH-UHFFFAOYSA-I pentasodium;[oxido(phosphonatooxy)phosphoryl] phosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O HWGNBUXHKFFFIH-UHFFFAOYSA-I 0.000 description 1
- 125000000864 peroxy group Chemical group O(O*)* 0.000 description 1
- JRKICGRDRMAZLK-UHFFFAOYSA-L persulfate group Chemical group S(=O)(=O)([O-])OOS(=O)(=O)[O-] JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 description 1
- 229940124531 pharmaceutical excipient Drugs 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- PATMLLNMTPIUSY-UHFFFAOYSA-N phenoxysulfonyl 7-methyloctanoate Chemical compound CC(C)CCCCCC(=O)OS(=O)(=O)OC1=CC=CC=C1 PATMLLNMTPIUSY-UHFFFAOYSA-N 0.000 description 1
- 229940067107 phenylethyl alcohol Drugs 0.000 description 1
- QCDYQQDYXPDABM-UHFFFAOYSA-N phloroglucinol Chemical compound OC1=CC(O)=CC(O)=C1 QCDYQQDYXPDABM-UHFFFAOYSA-N 0.000 description 1
- 229960001553 phloroglucinol Drugs 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 229920001515 polyalkylene glycol Polymers 0.000 description 1
- 229920005646 polycarboxylate Polymers 0.000 description 1
- 229920002959 polymer blend Polymers 0.000 description 1
- 229920000193 polymethacrylate Polymers 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 1
- 150000004804 polysaccharides Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 150000003138 primary alcohols Chemical class 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- XTHRMVQDBJOEPD-UHFFFAOYSA-N prop-1-ene;urea Chemical compound CC=C.NC(N)=O.NC(N)=O XTHRMVQDBJOEPD-UHFFFAOYSA-N 0.000 description 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940079877 pyrogallol Drugs 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 235000002020 sage Nutrition 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 150000004760 silicates Chemical class 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 229910021647 smectite Inorganic materials 0.000 description 1
- 235000017550 sodium carbonate Nutrition 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- QSKQNALVHFTOQX-UHFFFAOYSA-M sodium nonanoyloxybenzenesulfonate Chemical compound [Na+].CCCCCCCCC(=O)OC1=CC=CC=C1S([O-])(=O)=O QSKQNALVHFTOQX-UHFFFAOYSA-M 0.000 description 1
- 229940080313 sodium starch Drugs 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- RPACBEVZENYWOL-XFULWGLBSA-M sodium;(2r)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate Chemical compound [Na+].C=1C=C(Cl)C=CC=1OCCCCCC[C@]1(C(=O)[O-])CO1 RPACBEVZENYWOL-XFULWGLBSA-M 0.000 description 1
- MWNQXXOSWHCCOZ-UHFFFAOYSA-L sodium;oxido carbonate Chemical compound [Na+].[O-]OC([O-])=O MWNQXXOSWHCCOZ-UHFFFAOYSA-L 0.000 description 1
- 239000007944 soluble tablet Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 229910052712 strontium Inorganic materials 0.000 description 1
- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 150000003460 sulfonic acids Chemical class 0.000 description 1
- 239000007885 tablet disintegrant Substances 0.000 description 1
- 239000008399 tap water Substances 0.000 description 1
- 235000020679 tap water Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 150000003504 terephthalic acids Chemical class 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical class CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
- SDVHRXOTTYYKRY-UHFFFAOYSA-J tetrasodium;dioxido-oxo-phosphonato-$l^{5}-phosphane Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)P([O-])([O-])=O SDVHRXOTTYYKRY-UHFFFAOYSA-J 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 239000011135 tin Substances 0.000 description 1
- 229910052718 tin Inorganic materials 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052723 transition metal Inorganic materials 0.000 description 1
- 239000001226 triphosphate Substances 0.000 description 1
- UNXRWKVEANCORM-UHFFFAOYSA-I triphosphate(5-) Chemical compound [O-]P([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O UNXRWKVEANCORM-UHFFFAOYSA-I 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- ZFNVDHOSLNRHNN-UHFFFAOYSA-N xi-3-(4-Isopropylphenyl)-2-methylpropanal Chemical compound O=CC(C)CC1=CC=C(C(C)C)C=C1 ZFNVDHOSLNRHNN-UHFFFAOYSA-N 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
- 229910052726 zirconium Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/37—Polymers
- C11D3/3746—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
- C11D3/3749—Polyolefins; Halogenated polyolefins; Natural or synthetic rubber; Polyarylolefins or halogenated polyarylolefins
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
- C11D17/0047—Detergents in the form of bars or tablets
- C11D17/0065—Solid detergents containing builders
- C11D17/0073—Tablets
- C11D17/0078—Multilayered tablets
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
- C11D17/0047—Detergents in the form of bars or tablets
- C11D17/0065—Solid detergents containing builders
- C11D17/0073—Tablets
- C11D17/0091—Dishwashing tablets
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/37—Polymers
- C11D3/3746—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
- C11D3/3757—(Co)polymerised carboxylic acids, -anhydrides, -esters in solid and liquid compositions
- C11D3/3761—(Co)polymerised carboxylic acids, -anhydrides, -esters in solid and liquid compositions in solid compositions
Definitions
- the invention is directed to dishwashing detergent tablets which contain a granulate which absorbs water particularly well and forwards it to the interior. In this case, there is an increase in volume, so that this granulate is suitable as a disintegrant for pressed molded articles, in particular from detergent compositions for dishwashers.
- Machine dishwashing generally consists of a pre-rinse cycle, one or more intermediate rinses, a rinse cycle and a drying cycle. This applies in principle to mechanical washing both in households, as well as in the commercial sector.
- the detergents used for machine washing of dishes can be liquid, powdery, pasty or tablet-shaped.
- the use of tablets is becoming increasingly popular because of the ease of handling and metering. There are already described several manufacturing processes are obtained by the tablets with temporally influenced dissolution behavior. Such tablets are often no longer filled into the dosing in the door of the machine, but added directly into the engine room, whereby a certain part of the tablets is already dissolved in the pre-wash, thereby chemically supporting the effect of normally addition-free tap water in this rinse phase.
- DE-A-35 41 145 there are known uniformly composed alkaline dishwashing detergent tablets which have a broad solubility profile. These contain a mixture of Natriummetasilikatnonahydrat and anhydrous metasilicate and anhydrous pentasodium triphosphate and other ingredients.
- DE-A-41 21 307 are stable, bifunctional, phosphate and metasilikatschreib low-alkaline detergent tablets for automatic dishwashing known, the builders are partially used in anhydrous form and sprayed in the production with water, which causes the desired solubility profile and a very good compressibility.
- the solubility of the individual constituents or constituent mixtures is in EP-A-750 662 in that they are added to these hydrophobizing agents with different boiling and melting points.
- the pulverulent and / or crystalline constituents which contain no free water and no hydrated salts are coated alone or together with other readily soluble pulverulent or optionally granulated inorganic constituents by spraying on a liquid or liquefied hydrophobicizing compound. After addition of other components, the batch is compressed into tablets.
- DE-A-19 502 774 describes fracture-stable, easily soluble tablets obtained by the addition of sodium hypophosphate with high phase I content.
- Disintegrating agents for tablets or granules are auxiliaries which positively influence the disintegration of tablets or of the granules on contact with liquids, in particular water. In this case, both the disintegration of tablets in coarse parts and subsequently a disintegration into smaller particles is to be effected and accelerated.
- inorganic and organic substances As a disintegrating agent for tablets, a variety of inorganic and organic substances are known, for example, inorganic substances such as bentonites, persalts, acetates, alkali carbonates / bicarbonates and citric acid.
- organic compounds include starch, modified starch and starch degradation products, cellulose, cellulose ethers such as methylcellulose, hydroxypropylcellulose and carboxymethylcellulose, poly (meth) acrylates, polyvinylpyrrolidone and crosslinked polyvinylpyrrolidone, alginates, gelatin and pectins.
- disintegrants are citric acid or citrates, bicarbonates and carbonates, bisulfate and percarbonate, microcrystalline cellulose, sugar, sorbitol or swellable phyllosilicates. called by the type of bentonite or smectite.
- the disintegrants are used in amounts of 1 to 25 wt.% As a single raw material or as a compound.
- tablet disintegrants are incorporated into the tablet and preferably into the outer solid shell of the tablet.
- combinations of soluble acids and alkali carbonates are used.
- Other possible explosives can " Handbook of Pharmaceutical Excipients (1986 ). Examples include starch (modified starch sodium starch gluconate), gum (agar, guar, and others), cellulose, carboxymethyl cellulose, alginates, silica, clay, polyvinylpyrrolidone, polysaccharides, and ion exchange resins.
- the EP 1 043 388 describes dishwashing detergent tablets containing disintegrant granules comprising cellulose and polymers / copolymers of (meth) acrylic acid.
- the object of the invention is to provide compressed molded articles of washing and cleaning formulations, in particular for machine dishwashing detergents, which contain a particularly effective disintegrating agent, so that they disintegrate quickly and effectively both in the metering chamber, as well as in the cutlery basket of the Geschirrutzs.
- phosphate-containing or phosphate-free dishwasher cleaning tablets characterized in that in addition to conventional constituents in at least one phase as a disintegrating agent is a compacted granules containing at least one polymer comprising ⁇ -olefins as monomeric units, wherein the polymer a copolymer of ⁇ -olefin and units of a cis-bifunctional acid, especially maleic acid.
- the disintegrant contains a combination of such a polymer with water-swellable cellulose and / or cellulose derivatives, or cellulose-containing material, wherein the polymer is a copolymer of ⁇ -olefin and units of a cis-bifunctional acid, in particular maleic acid.
- the water-swellable cellulose is used in the form of cellulose fibers or microcrystalline cellulose, wherein the supermolecular structural elements may take the form of fibrils in the longitudinal direction of which crystalline and amorphous regions may alternate. Fibrils of native cellulose having a maximum length of 300 ⁇ m have proven particularly suitable. Both microcrystalline and amorphous cellulose (derivatives) and mixtures thereof can be used.
- Cellulosic material should be one in which cellulose is at least predominantly chemically unchanged. As cellulosic material is primarily TMP (Thermo Mechanical Pulp) and CTMP (Chemo Thermo Mechanical Pulp) into consideration. There are two types of so-called wood pulp. In the TMP process wood chips are fiberized under pressure of steam at about 130 ° C in pressure refiner to TMP. When using chemicals in wood chip damping, CTMP (see Römpp Chemie-Lexikon 9th Edition (1995), page 3207 Keyword "paper”). The cellulose-containing material is preferably used with particle sizes of from 20 to 200 .mu.m, more preferably from 40 to 60 .mu.m (before compaction).
- cellulose is used in purified form (commercial cellulose), this preferably has bulk densities of from 40 g / l to 350 g / l, very particularly preferably from 65 g / l to 170 g / l. If already granulated types are used, their bulk density is higher and can be from 350 g / l to 550 g / l.
- the bulk densities of the cellulose derivatives may be in the range of 50 g / l to 1000 g / l, preferably in the range of 100 g / l and 800 g / l.
- the particle size of the cellulose can be between 30 .mu.m and 400 .mu.m, in the case of granulated types, the average particle size is between 350 .mu.m and 800 .mu.m.
- the particle size of the cellulose derivatives or of the cellulose-containing materials can be between 30 ⁇ m and 3000 ⁇ m.
- the polymer used for the disintegrant is a copolymer which may comprise units of at least one ⁇ -olefin of any type, e.g. Olefins having 2 to 18 carbon atoms, wherein the double bond (s) may be represented at any position.
- the disintegrating agent according to the invention is a copolymer of an ⁇ -olefin and a cis-bifunctional acid, more preferably maleic acid.
- the salt formation is preferably carried out with cations of alkali, ammonia and amines, or mixtures thereof.
- a particularly preferred disintegrant comprises a maleic-olefin copolymer available in the form of its Na salt under the trade name Sokalan® CP9 from BASF, Germany.
- Sokalan® CP9 has hitherto only been known as a dispersant for organic and inorganic solids in aqueous and aqueous-organic media, in liquid form. The use as granules and the use as a disintegrant is not yet described.
- the particle size of the polymer / copolymer used in the granules should preferably not exceed 800 .mu.m, since the particles can otherwise settle visibly on the dishes.
- the disintegrating agent may consist entirely of said polymer, or it may be a mixture of such a polymer with cellulose (derivatives) or cellulose-containing material.
- the proportion of cellulose (derivatives) or of the cellulose-containing material in the disintegrant granulate can be from 50 to 99% by weight, preferably from 70 to 97% and particularly preferably from 80 to 95% by weight.
- the proportion of the polymer can be from 50 to 1% by weight, preferably from 30 to 3% by weight, particularly preferably from 20 to 5% by weight, of the disintegrant granulate.
- regenerated celluloses such as viscose may also be used.
- cellulose ethers Due to their water-absorbing capacity, water-swellable cellulose derivatives such as cellulose ethers and cellulose esters and mixed modifications thereof are also useful. Suitable cellulose ethers are, for example, methylcellulose, hydroxypropylcellulose and carboxymethylcellulose, as well as modified carboxymethylcellulose.
- the granules may contain water-swellable cellulose derivatives and starch or starch derivatives and other swellable polysaccharides and polygalactomannans, for example ionically modified celluloses and starches such as carboxymethyl modified cellulose and starch, nonionic modified celluloses and starches such as alkoxylated celluloses and starches such as hydroxypropyl and hydroxyethyl starch or hydroxypropyl and hydroxyethyl cellulose and alkyletherethererte products such as methylcellulose and mixed modified celluloses and starches from the aforementioned modifications, which leads to crosslinking.
- ionically modified celluloses and starches such as carboxymethyl modified cellulose and starch
- nonionic modified celluloses and starches such as alkoxylated celluloses and starches such as hydroxypropyl and hydroxyethyl starch or hydroxypropyl and hydroxyethyl cellulose and alkyletherethererte products
- Suitable starches are also cold-swelling starches which are formed by mechanical or degrading reactions on the starch grain. These include, above all, swelling powders from extruder and drum dryer processes as well as enzymatically, oxidatively or acid-degrading modified products. Chemically derivatized starches preferably contain substituents attached to the polysaccharide chains in sufficient numbers by ester and ether groups.
- Pure cellulose and cellulose derivatives may also be used together with other modified water-swellable polysaccharide derivatives, e.g. Starch and / or starch derivatives may be present in the granules to be used according to the invention.
- modified water-swellable polysaccharide derivatives e.g. Starch and / or starch derivatives may be present in the granules to be used according to the invention.
- Starches modified with ionic substituents such as carboxylate, hydroxyalkyl or phosphate groups have been found to be particularly advantageous. To improve the swelling behavior, the use of easily cross-linked starches has proven itself. Also alkaline treated starches can be used because of their good cold water swellability.
- the combination of cellulose with cellulose derivatives and / or starch and / or starch derivatives has proven itself.
- the proportions can vary within wide limits, based on the combination, the proportion of cellulose derivatives and / or starch and / or starch derivatives preferably 0.1 to 85 wt.%, Particularly preferably 5 to 50 wt.%.
- the disintegrant granules may also comprise other types of polymers, such as e.g. finely divided and / or aqueous solutions of soluble polymers of (meth) acrylic acid or copolymers of (meth) acrylic acid or salts thereof or mixtures of such polymers or copolymers or salts thereof with high water absorption capacity.
- polymers such as e.g. finely divided and / or aqueous solutions of soluble polymers of (meth) acrylic acid or copolymers of (meth) acrylic acid or salts thereof or mixtures of such polymers or copolymers or salts thereof with high water absorption capacity.
- Suitable are linear polymers of (meth) acrylic acid, copolymers of (meth) acrylic acid or salts thereof having weight average molecular weights of 5,000 to 70,000 and crosslinked polymers of (meth) acrylic acid, copolymers of (meth) acrylic acid or salts thereof having weight average molecular weights of 1,000 .000 to 5,000,000 can be viewed.
- the copolymers are preferably copolymers of (meth) acrylic acid and maleic acid or maleic anhydride, which contain, for example, 40 to 90% by weight of (meth) acrylic acid and 60 to 10% by weight of maleic acid or maleic anhydride, their relative molar mass, based on free Acids, between 3,000 and 100,000, preferably 3,000 to 70,000 and most preferably 5,000 to 50,000.
- ter- and quattropolymere polycarboxylates may be contained, prepared from (meth) acrylic acid.
- the polymers are preferably used in the preparation of the granules in the form of their aqueous solutions, but can also be used in the form of finely divided powders.
- the polymers / copolymers used according to the invention can be incorporated particularly well into the granules if they are at most 800 ⁇ m in size.
- Suitable co-binders which simultaneously have a surfactant character are so-called polymer surfactants. These are understood to mean reaction products which, in addition to the typical polymer structures of the abovementioned polymers, have additional structural elements which unfold a surfactant effect. Examples of these are graft polymers with alkoxylated fatty alcohol or carboxylate-containing polymers with methoxyalkylene oxide monomer units, furthermore maleic acid / vinyl ethers / longer-chain fatty amine copolymers and also hemiamides of maleic acid copolymers and copolymers of acrylic acid with long-chain acrylates. In a preferred embodiment, the polymeric surfactants contain alkylene oxide units.
- the polymer surfactants can also be incorporated alone, ie without a polymeric binder component and without a surfactant component, into the disintegrant granules.
- the polymer surfactants will be present in the disintegrant granules with a proportion of up to 30% by weight, as sole component with 1 to 40% by weight, preferably with 5 to 20% by weight.
- a "mixed granulate” the polymers / copolymers containing ⁇ -olefins as monomeric units and units of a cis-bifunctional acid, for example ⁇ -olefins and maleic acid, or salts thereof with cellulose (derivatives), or cellulose-containing material and optionally further modified water-swellable polysaccharide derivatives in the granules combined, wherein the weight ratio (cellulose (derivative) / cellulosic material: polymer) of 50: 1 to 1: 1, preferably from 20: 1 to 5: 1, most preferably is a weight ratio of 12: 1 to 8: 1.
- the polymers / copolymers or salts thereof together with cellulose (derivatives) or the cellulose-containing material are predispersed in water, wet granulated and then dried.
- the wet granulation and the subsequent evaporation gives the granules a porous structure in which the polymer / copolymer or its salt is attached to the surface of the cellulose, of the cellulose derivative or of the cellulose-containing material.
- the granules are preferably dried to a residual water content of 1 to 8% by weight, based on the weight of the granules.
- the porous structure gives a particularly favorable absorption capacity for liquids, in the case of water with rapid volume increase.
- the disintegrant granules to be used according to the invention are initially produced by mixing the granule constituents to be used according to the invention with customary mixing processes. For example, mixers from Vomm, Lödige, Schugi, Eirich, Henschel or Fukae can be used.
- precompounds are produced by agglomeration processes. These precompounds form a free-flowing product which has a water content of between 10 and 80% by weight.
- the required water content in the premix depends on the compressor used.
- a water content of at least 10% by weight, preferably 20% by weight, is required in order to achieve good compaction. and to guarantee a high liquid absorption in the later dry granulate.
- these precompounds are mechanically compacted.
- the final compaction is essential.
- the compression using pressure can be done in various ways.
- the products can be placed between two pressure surfaces in roller compactors, e.g. smooth or profiled, compacted.
- the output of the Kompaktats takes place as a strand.
- Densification methods in dies with punches or pillow rolls result in copactate forms such as tablets or briquettes.
- Roller compactors, extruders, roller or die presses, but also granulation presses can be used as compacting machines.
- pelleting presses Compaction with pelleting presses has proved particularly suitable, granules being obtained by suitable process control which can be dried without further comminution.
- suitable pelleting presses are e.g. produced by the companies Amandus Kahl and Fitzpatrick.
- conventional dryers such as e.g. Drum dryers (temperatures, for example, from 95 to 120 ° C) or fluidized bed dryers (temperatures, for example, from 70 to 100 ° C).
- the coarse, compacted particles are comminuted, e.g. Mills, shredders or roller mills are suitable.
- the comminution can be carried out before or after drying.
- the granules are adjusted to a particle size distribution of 0.05 to 3 mm, preferably 0.1 to 1.5 mm.
- the removal of dust particles below 0.1 mm may e.g. be carried out with conventional screening devices.
- any other conventional method may also be used, e.g. the spraying in the spray granulation in a fluidized bed, but for the swelling and water absorption behavior of the disintegrant granules according to the invention, but the wet granulation and subsequent drying has been found to be particularly suitable.
- the polymer used is "frozen” by the granulation and drying process in a particular three-dimensional "cocked” configuration. Upon contact with water, the "frozen” configuration is changed very quickly in favor of another configuration in which the hydrophobic and hydrophilic regions of the polymer align in the water to bring the polymer into an energetically favorable state. The blasting effect is thus based on a configuration change of the polymer used.
- the configuration change is particularly pronounced if the granules used as disintegrants consist entirely of a polymer containing at least one ⁇ -olefin and units of a cis-bifunctional acid.
- granules are obtained by the wet granulation and the subsequent drying of cellulose / cellulose derivatives predispersed in water together with the polymer / copolymer, or the cellulose-containing material and / or starch / starch derivatives, which also has a high explosive effect.
- the Efficiency is presumably achieved by the capillary action of the pores and the rapid penetration of the granules with water.
- Shaped bodies of various compositions of cleaning formulations. containing such granules according to the invention are rapidly and effectively blasted when used in dosing or direct addition in baskets of domestic or commercial dishwashers.
- the disintegrant granules to be used according to the invention have bulk densities of from 80 g / l to 800 g / l, preferably from 100 g / l to 500 g / l, very particularly preferably from 250 g / l to 400 g / l, and are in the layer (s) (s) / range (s) of the molded articles in which they are present in amounts of from 1% by weight to 15% by weight, preferably from 2% by weight to 10% by weight and more preferably from 3 to 6% by weight.
- the granules on contact with water this increases rapidly under volume and is therefore suitable as a disintegrant for pressed moldings, so that they rapidly disintegrate in water.
- Such moldings must have sufficient stability and strength to allow handling, packaging and storage, but should disintegrate rapidly on contact with water, so that the ingredients can develop the desired effect.
- the invention relates to compressed molded articles, for example tablets, cubes, cuboids, spheres and the like, in which a compacted, porous granules are contained as disintegrating agents.
- the shaped articles can consist of any type of composition which can be broken up into their individual parts, in particular of detergent compositions.
- Moldings of detergent formulations for dishwashers in tablet, bar or cube form are particularly preferred.
- the detergent tablets may be pressed from only one detergent composition (single-phase tablets), or they may consist of several phases, layers or regions, e.g. two- or three-phase molded bodies (e.g., "3 in 1").
- individual components of the cleaning agent can be separated from each other, so that they are provided at different times during the cleaning process.
- An example of this is the separation of the cleaning, the salt function and the rinse aid function into individual regions of the molding used.
- the spatial form of the moldings can be adapted in their dimensions of the dispensing compartment of the dishwasher, but all reasonable manageable shapes can be designed. These include e.g. also cylindrical embodiments with an oval or circular cross-section and shaped body with a plate or panel-like structure.
- a preferred shaped body consists of alternately thick long and thin short segments, so that individual segments of such a bar at predetermined breaking points, which are represented by the short thin segments, broken and can be entered into the metering chamber or the cutlery basket of the machine. This principle of the bar-shaped shaped body can also be realized in other geometric polygonal shapes.
- a tablet produced in this way preferably has a weight of from 5 to 120 g, particularly preferably from 10 to 30 g, with diameters of from 20 to 50 mm being preferred.
- Detergent tablets for different purposes, especially for dishwashers are basically known.
- Such detergent formulations formed as shaped articles generally comprise builders, bleaching agents and bleach activators, surfactants, tableting aids, disintegrants and other customary additives and auxiliaries.
- the composition of the cleaning agent which is present as a molded body, not decisive, as long as it is a composition which is suitable as a cleaning agent, especially for use in a dishwasher.
- Any conventional moldable composition suitable for this purpose may be mixed with the disintegrant granules of the present invention and compressed.
- the compositions described below are merely preferred embodiments of the detergent compositions without the granules being useful only in such compositions.
- a preferred embodiment of the invention is a phosphate-containing dishwashing detergent tablet containing: 10 to 75 parts by weight.
- Polyphosphate (s) 60 to 0 parts by weight. other inorganic builders, 20 to 0 parts by weight. organic builders, 7 to 20 parts by weight peroxide bleaching agent, 10 to 1 parts by weight.
- Bleach activator (s) 0 to 16 parts by weight.
- Surfactant (s) 0.1 to 10 parts by weight.
- a phosphate-free dishwashing detergent tablet comprising: 0 to 50 parts by weight. Citrate (s) / citric acid, 36 to 0 parts by weight. Silicate, 32 to 0 parts by weight Na carbonate, 0 to 20 parts by weight. bicarbonate, 10 to 0 parts by weight. polymeric organic builders, 4 to 18 parts by weight peroxide bleaching agent, 8.8 to 1 part by weight. Bleach activator (s), 0.2 to 16 parts by weight. Surfactant (s), 10 to 0.1 parts by weight. Disintegrator granules, 1 to 5 parts by weight other, customary auxiliaries and additives.
- both mono-, as well as double or triple tablets are preferred.
- the disintegrant may be included in all layers / phases of the cleaning tablet, but is preferably contained in only one or two (in the presence of multiple layers / phases) layers / phases. This is preferred to dissolve a first layer / phase containing rapidly acting ingredients in the rinse water in a short time and to provide the ingredients therewith, while another layer / phase containing ingredients will be at a later time the rinsing process to be used, slower dissolves, since it contains no or a "slower" disintegrant.
- Suitable builders in the detergent composition are all customary and known builders, in particular polyphosphates, pyrophosphates, metaphosphates or phosphonates, sheet silicates, amorphous silicates, amorphous disilicates and zeolites, and fillers such as sodium carbonate, sodium sulfate, magnesium sulfate, sodium bicarbonate, citrate and citric acid, Succinic, tartaric and malic acid.
- co-builders and dispersants are used as auxiliary builder.
- Such co-builders or dispersants may be, inter alia, polyacrylic acids or copolymers with polyacrylic acid and its sodium salts.
- Typical bleaching agents are, for example, sodium perborate tetrahydrate and sodium perborate monohydrate, sodium percarbonate, peroxypyrophosphates, citrate perhydrates, and H 2 O 2 -forming peracidic salts, peracids, such as perbenzoates, peroxyphthalates, diperazelaic acid and diperdodecanedioic acids.
- peracids such as perbenzoates, peroxyphthalates, diperazelaic acid and diperdodecanedioic acids.
- bleaching agents or bleach systems may also be present in the composition.
- suitable peroxygen compounds are in particular hydrogen peroxide and under the washing conditions hydrogen peroxide donating inorganic salts to which alkali metal perborates such.
- Sodium perborate tetrahydrate and sodium perborate monohydrate further include alkali metal carbonate perhydrates such as sodium carbonate perhydrate ("sodium percarbonate”) and persilicates and / or persulfates such as caroate.
- the bleach system of the detergent formulation may contain inorganic or organic peracids, especially percarboxylic acids, e.g. B.
- acids which can be used are peracetic acid, perbenzoic acid, linear or branched octane, nonane, decane or dodecane monoperacids, decane and dodecane diperacids, mono- and diperphthalic acids, isophthalic and terephthalic acids, phthalimidopercaproic acid, terephthaloyldiamidopercaproic acid and e-phthalimido peroxohexanoic acid (PAP).
- peracetic acid perbenzoic acid
- linear or branched octane nonane
- decane or dodecane monoperacids
- decane and dodecane diperacids mono- and diperphthalic acids
- isophthalic and terephthalic acids phthalimidopercaproic acid
- terephthaloyldiamidopercaproic acid e-phthalimido peroxohexanoic acid (PAP).
- percarboxylic acids can be used as free acids or as salts of the acids, preferably alkali or alkaline earth metal salts.
- solid peroxygen compounds are to be used, they can be used in the form of powders or granules, which can also be enveloped in a manner known in principle.
- a particularly preferably used peracid is the peracid available under the trade name Eureco® (Ausimont, Italy).
- Peroxygen compounds are present in amounts of preferably up to 50% by weight, more preferably from 5% to 30% and most preferably from 8% to 25% by weight.
- bleach stabilizers such as phosphonates, borates or metaborates and metasilicates and magnesium salts such as magnesium sulfate may be useful.
- the content of bleaching agents in tablets is preferably 5-60% by weight and especially 7-20% by weight.
- bleach catalysts usually quaternized imines or sulfonimines are used, as described for example in US-A-5,360,568 . US-A-5,360,569 and EP-A-453 003 are described, as well as manganese complexes, such as those in WO-A 94/21777 are described. Further usable metal-containing bleach catalysts are in EP-A-458,397 . EP-A-458,398 and EP-A-549 272 described. Bleach catalysts are generally used in amounts of up to 1 wt .-%, in particular 0.01 to 0.5 wt .-%, based on the detergent formulation.
- Suitable bleach activators are the H 2 O 2 organic peracids forming N-acyl and O-acyl compounds, preferably N, N'-tetraacylated diamines, carboxylic anhydrides and esters of polyols such as glucose pentaacetate. Further, acetylated mixtures of sorbitol and mannitol may be used. Particularly suitable as bleach activators are N, N, N ', N'-tetraacetylethylenediamine (TAED), 1,5-diacetyl-2,4-dioxo-hexahydro-1,2,5-triazine (DADHT) and acetylated sorbitol-mannitol. Mixtures (SORMAN).
- compounds of the substance classes of polyacylated sugar or sugar derivatives with C 1 -C 10 -acyl radicals can be used, preferably with acetyl, propionyl, octanoyl, nonanoyl or benzoyl radicals, in particular acetyl radicals.
- Suitable sugars or sugar derivatives are mono- or disaccharides and their reduced or oxidized derivatives, preferably glucose, mannose, fructose, sucrose, xylose or lactose.
- bleach activators of this class of substances are, for example, pentaacetylglucose, xylose tetraacetate, 1-benzoyl-2,3,4,6-tetraacetylglucose and 1-octanoyl-2,3,4,6-tetraacetylglucose.
- O-Acyloximester such as O-acetylactone oxime, O-benzoylacetone oxime, bis (propylimino) carbonate or bis (cyclohexylimino) carbonate.
- acylated oximes and oxime esters are described for example in US Pat EP-A-028432 and the EP-A-267 046 ,
- N-acyl caprolactams such as N-acetyl caprolactam, N-benzoyl caprolactam, N-octanoyl caprolactam, N-octanoyl caprolactam, or carbonyl biscaprolactam.
- bleach activators are 2-alkyl- or 2-aryl- (4H) -3,1-benzoxain-4-ones, as described, for example, in US Pat EP-B-332 294 and the EP-B-502 013 are described.
- 2-phenyl- (4H) -3,1-benzoxain-4-one and 2-methyl- (4H) -3,1-benzoxain-4-one are useful.
- bleach activators from the classes of N- or O-acyl compounds for example polyacylated alkylenediamines, in particular tetraacetylethylenediamine, acylated glycolurils, in particular tetraacetylglycoluril, N-acylated hydantoins, hydrazides, triazoles, hydrotriazines, urazoles, diketopiperazines, sulfurylamides and cyanurates, also carboxylic acid anhydrides , in particular phthalic anhydride, carboxylic acid esters, in particular sodium nonanoyloxy-benzenesulfonate, sodium isononanoyloxy-benzenesulfonate and acylated sugar derivatives, such as pentaacetyl-glucose are used.
- polyacylated alkylenediamines in particular tetraacetylethylenediamine
- acylated glycolurils in particular tetra
- a preferred bleach activator is a quaternized glycine nitrile from the group consisting of N-methylmorpholinium acetonitrile methyl sulfate, sulfate and hydrogen sulfate.
- bleach system (bleach and bleach activators), all those in the DE 199 59 589 A1 be mentioned bleaches and activators.
- bleach systems described in European Patent Application EP 02 028 958.3 called are used.
- the different constituents of the detergent composition are contained in different phases / layers / regions of the moldings.
- a Ingredient to be provided late in the cleaning process is located in a phase / layer / area in which no disintegrant is contained.
- the cleaning agents may also contain one or more surfactants (s) from the group of nonionic, anionic, cationic and / or amphoteric surfactants.
- nonionic surfactants in the detergent composition only in small amounts, preferably below about 16% by weight, more preferably in ranges of from 0 to 8% by weight of the detergent, or in the detergent phase, which preferably contains the disintegrant.
- Detergents come from the groups of surfactants, enzymes, corrosion inhibitors and dyes and fragrances. These substances are described below.
- the nonionic surfactants used are preferably alkoxylated, advantageously ethoxylated, in particular primary, alcohols having preferably 8 to 18 carbon atoms and on average 1 to 12 moles of ethylene oxide (EO) per mole of alcohol, in which the alcohol radical can be linear or preferably methyl-branched in the 2-position or linear and methyl-branched radicals in the mixture can contain, as they are usually present in Oxoalkoholresten.
- EO ethylene oxide
- the preferred ethoxylated alcohols include, for example, C 12 -C 14 -alcohols with 3 EO or 4 EO, C 9 -C 11 -alcohols with 7 EO, C 13 -C 15 -alcohols with 3 EO, 5 EO, 7 EO or 8 EO, C 12 -C 18 -alcohols with 3 EO, 5 EO or 7 EO and mixtures of these, such as mixtures of C 12 -C 14 -alcohol with 3 EO and C 12 -C 18 -alcohol with 5 EO.
- the degrees of ethoxylation given represent statistical means which, for a particular product, may be an integer or a fractional number.
- Preferred alcohol ethoxylates have a narrow homolog distribution (narrow range ethoxylates, NRE).
- fatty alcohols with more than 12 EO can also be used. Examples include tallow fatty alcohol with 14 EO, 25 EO, 30 EO or 40 EO.
- nonionic surfactants and alkyl glycosides of the general formula RO (G) x can be used in which R is a primary straight-chain or methyl-branched, especially in the 2-position methyl-branched aliphatic radical having 8 to 22, preferably 12 to 18 carbon atoms and G is the symbol which represents a glycose unit having 5 or 6 C atoms, preferably glucose.
- the degree of oligomerization x which indicates the distribution of monoglycosides and oligoglycosides, is any number between 1 and 10; preferably x is 1.2 to 1.4.
- nonionic surfactants used either as the sole nonionic surfactant or in combination with other nonionic surfactants are alkoxylated, preferably ethoxylated or ethoxylated and propoxylated fatty acid alkyl esters, preferably having from 1 to 4 carbon atoms in the alkyl chain, especially fatty acid methyl esters.
- Nonionic surfactants of the amine oxide type for example N-cocoalkyl-N, N-dimethylamine oxide and N-tallowalkyl-N, N-dihydroxyethylamine oxide, and the fatty acid alkanolamides may also be suitable.
- the amount of these nonionic surfactants is preferably not more than that of the ethoxylated fatty alcohols, especially not more than half thereof.
- polyhydroxy fatty acid amides of the formula (I) wherein RCO is an aliphatic acyl group having 6 to 22 carbon atoms, R 1 is hydrogen, an alkyl or hydroxyalkyl group having 1 to 4 carbon atoms and [Z] is a linear or branched polyhydroxyalkyl group having 3 to 10 carbon atoms and 3 to 10 hydroxyl groups.
- the polyhydroxy fatty acid amides are known substances which can usually be obtained by reductive amination of a reducing sugar with ammonia, an alkylamine or an alkanolamine and subsequent acylation with a fatty acid, a fatty acid alkyl ester or a fatty acid chloride.
- the group of polyhydroxy fatty acid amides also includes compounds of the formula (II)
- R is a linear or branched alkyl or alkenyl radical having 7 to 12 carbon atoms
- R 1 is a linear, branched or cyclic alkyl radical or an aryl radical having 2 to 8 carbon atoms
- R 2 is a linear, branched or cyclic alkyl radical or an aryl radical or an oxyaryl radical having 1 to 8 carbon atoms, wherein C 1 -C 4 alkyl or phenyl radicals are preferred and [Z] is a linear polyhydroxyalkyl radical whose alkyl chain is substituted by at least two hydroxyl groups, or alkoxylated, preferably ethoxylated or propoxylated derivatives of this residue.
- [Z] is preferably obtained by reductive amination of a reduced sugar, for example glucose, fructose, maltose, lactose, galactose, mannose or xylose.
- a reduced sugar for example glucose, fructose, maltose, lactose, galactose, mannose or xylose.
- the N-alkoxy- or N-aryloxy-substituted compounds can then be converted into the desired polyhydroxy fatty acid amides by reaction with fatty acid methyl esters in the presence of an alkoxide as catalyst.
- the automatic dishwashing detergent tablets according to the invention comprise nonionic surfactants, in particular nonionic surfactants from the group of the alkoxylated alcohols.
- the nonionic surfactants used are preferably alkoxylated, advantageously ethoxylated, in particular primary, alcohols having preferably 8 to 18 carbon atoms and on average 1 to 12 moles of ethylene oxide (EO) per mole of alcohol, in which the alcohol radical can be linear or preferably methyl-branched in the 2-position or linear and methyl-branched radicals in the mixture can contain, as they are usually present in Oxoalkoholresten.
- EO ethylene oxide
- the preferred ethoxylated alcohols include, for example, C 12 -C 14 -alcohols with 3 EO or 4 EO, C 9 -C 11 -alcohol with 7 EO, C 13 -C 15 -alcohols with 3 EO, 5 EO, 7 EO or 8 EO, C 12 -C 18 -alcohols with 3 EO, 5 EO or 7 EO and mixtures of these, such as mixtures of C 12 -C 14 -alcohol with 3 EO and C 12 -C 18 -alcohol with 5 EO.
- the degrees of ethoxylation given represent statistical means which, for a particular product, may be an integer or a fractional number.
- Preferred alcohol ethoxylates have a narrow homolog distribution (narrow range ethoxylates, NRE).
- fatty alcohols with more than 12 EO can also be used. Examples include tallow fatty alcohol with 14 EO, 25 EO, 30 EO or 40 EO.
- detergent tablets according to the invention which contain a nonionic surfactant which has a melting point above room temperature.
- preferred detergent tablets are characterized in that they contain as ingredient c) nonionic surfactant (s) having a melting point above 20 ° C, preferably above 25 ° C, more preferably between 25 and 60 ° C and in particular between 26, 6 and 43.3 ° C included.
- Suitable nonionic surfactants which have melting or softening points in the temperature range mentioned are, for example, low-foaming nonionic surfactants which may be solid or highly viscous at room temperature. If high-viscosity nonionic surfactants are used at room temperature, it is preferred that they have a viscosity above 20 Pas, preferably 35 Pas and in particular above 40 Pas. Nonionic surfactants which have waxy consistency at room temperature are also preferred.
- Preferred nonionic surfactants to be used at room temperature are from the groups of the alkoxylated nonionic surfactants, in particular the ethoxylated primary alcohols, and mixtures of these surfactants with structurally complicated surfactants such as polyoxypropylene / polyoxyethylene / polyoxypropylene (PO / EO / PO) surfactants.
- Such (PO / EO / PO) nonionic surfactants are also characterized by good foam control.
- the nonionic surfactant having a melting point above room temperature is an ethoxylated nonionic surfactant consisting of the reaction of a monohydroxyalkanol or alkylphenol having 6 to 20 carbon atoms, preferably at least 12 mol, more preferably at least 15 mol, especially at least 25 moles of ethylene oxide per mole of alcohol or alkylphenol emerged.
- a particularly preferred room temperature solid nonionic surfactant is selected from a straight-chain fatty alcohol having 16 to 20 carbon atoms (C 16 -C 20 -alcohol), preferably a C 18 -alcohol and at least 12 mol, preferably at least 15 mol and in particular at least 25 mol of ethylene oxide.
- C 16 -C 20 -alcohol straight-chain fatty alcohol having 16 to 20 carbon atoms
- C 18 -alcohol preferably a C 18 -alcohol and at least 12 mol, preferably at least 15 mol and in particular at least 25 mol of ethylene oxide.
- the so-called “narrow range ethoxylates" are particularly preferred.
- the nonionic surfactant solid at room temperature preferably additionally has propylene oxide units in the molecule.
- such PO units make up to 25 wt .-%, particularly preferably 20 wt .-% and in particular up to 15 wt .-% of the total molecular weight of the nonionic surfactant from.
- Particularly preferred nonionic surfactants are ethoxylated monohydroxyalkanols or alkylphenols which additionally have polyoxyethylene-polyoxypropylene block copolymer units.
- the alcohol or alkylphenol part of such nonionic surfactant molecules preferably constitutes more than 30% by weight, more preferably more than 50% by weight and in particular more than 70% by weight of the total molecular weight of such nonionic surfactants.
- nonionic surfactants having melting points above room temperature contain from 40 to 70% of a polyoxypropylene / polyoxyethylene block polymer blend containing 75% by weight of a reverse block copolymer of polyoxyethylene and polyoxypropylene with 17 moles of ethylene oxide and 44 moles of propylene oxide and 25% by weight of a block copolymer of polyoxyethylene and polyoxypropylene initiated with trimethylolpropane and containing 24 moles of ethylene oxide and 99 moles of propylene oxide per mole of trimethylolpropane.
- Nonionic surfactants which may be used with particular preference are available, for example, under the name Poly Tergent® SLF-18 from Olin Chemicals.
- Further preferred detergent tablets according to the invention contain nonionic surfactants of the formula R 1 O [CH 2 CH (CH 3 ) O] x [CH 2 CH 2 O] y [CH 2 CH (OH) R 2 ], in which R 1 represents a linear or branched aliphatic hydrocarbon radical having 4 to 18 carbon atoms or mixtures thereof, R 2 denotes a linear or branched hydrocarbon radical having 2 to 26 carbon atoms or mixtures thereof and x is values between 0.5 and 1.5 and y is a value of at least 15 ,
- nonionic surfactants which may be used are the end-capped poly (oxyalkylated) nonionic surfactants of the formula R 1 O [CH 2 CH (R 3 ) O] x [CH 2 ] k CH (OH) [CH 2 ] j OR 2 in which R 1 and R 2 is linear or branched, saturated or unsaturated, aliphatic or aromatic hydrocarbon radicals having 1 to 30 carbon atoms, R 3 is H or a methyl, ethyl, n-propyl, iso-propyl, n-butyl, 2 X is butyl or 2-methyl-2-butyl radical, x are values between 1 and 30, k and j are values between 1 and 12, preferably between 1 and 5.
- each R 3 in the above formula may be different.
- R 1 and R 2 are preferably linear or branched, saturated or unsaturated, aliphatic or aromatic hydrocarbon radicals having 6 to 22 carbon atoms, with radicals having 8 to 18 carbon atoms being particularly preferred.
- R 3 H, -CH 3 or -CH 2 CH 3 are particularly preferred.
- Particularly preferred values for x are in the range from 1 to 20, in particular from 6 to 15.
- each R 3 in the above formula may be different if x is 2.
- the alkylene oxide unit in the square bracket can be varied.
- the value 3 for x has been selected here by way of example and may well be greater, with the variation width increasing with increasing x values and including, for example, a large number (EO) groups combined with a small number (PO) groups, or vice versa ,
- R 1 , R 2 and R 3 are as defined above and x is from 1 to 30, preferably from 1 to 20 and in particular from 6 to 18.
- Particularly preferred are surfactants in which the radicals R 1 and R 2 has 9 to 14 C atoms, R 3 is H and x assumes values of 6 to 15.
- Suitable enzymes in the detergent tablets according to the invention are, in particular, those from the classes of hydrolases, such as proteases, esterases, lipases or lipolytic enzymes, amylases, glycosyl hydrolases and mixtures of said enzymes. All of these hydrolases contribute to the removal of stains such as proteinaceous, fatty or starchy stains. For bleaching and oxidoreductases can be used. Particularly suitable are bacterial strains or fungi such as Bacillus subtilis, Bacillus licheniformis, Streptomyces griseus, Coprinus cinereus and Humicola insolens as well as from their genetically modified variants obtained enzymatic agents.
- hydrolases such as proteases, esterases, lipases or lipolytic enzymes, amylases, glycosyl hydrolases and mixtures of said enzymes. All of these hydrolases contribute to the removal of stains such as proteinaceous, fatty or starchy stains.
- subtilisin-type proteases and in particular proteases derived from Bacillus lentus are used.
- enzyme mixtures for example from protease and amylase or protease and lipase or lipolytic enzymes or from protease, amylase and lipase or lipolytic enzymes or protease, lipase or lipolytic enzymes, but in particular protease and / or lipase-containing mixtures or Mixtures with lipolytic enzymes of particular interest.
- lipolytic enzymes are the known cutinases.
- Peroxidases or oxidases have also proved suitable in some cases.
- Suitable amylases include in particular ⁇ -amylases, iso-amylases, pullulanases and pectinases.
- the enzymes may be adsorbed to carriers or embedded in encapsulants to protect against premature degradation.
- the proportion of enzymes, enzyme mixtures or enzyme granules can, for example, about 0.1 to 5 wt .-%, preferably 0.5 to about 4.5 wt .-% amount.
- preferred detergent tablets are characterized in that they contain protease and / or amylase.
- detergent moldings are preferred in which the enzyme (s) is / are not contained in one phase together with the bleach-enhancing active ingredient combination.
- Detergent tablets characterized in that at least one phase contains bleach while at least one other phase contains enzymes are also preferred embodiments of the present invention.
- the detergents according to the invention may contain corrosion inhibitors for protecting the items to be washed or the machine, with silver protectants in particular being of particular importance in the field of automatic dishwashing. It is possible to use the known substances of the prior art. In general, especially silver protectants can be selected from the group of the triazoles, the benzotriazoles, the bisbenzotriazoles, the aminotriazoles, the alkylaminotriazoles and the transition metal salts or complexes are used. Particularly preferred to use are benzotriazole and / or alkylaminotriazole. In addition, cleaner formulations often contain active chlorine-containing agents which can markedly reduce the corrosion of the silver surface.
- chlorine-free cleaners are particularly oxygen and nitrogen-containing organic redox-active compounds such as di- and trihydric phenols, eg. As hydroquinone, pyrocatechol, hydroxyhydroquinone, gallic acid, phloroglucinol, pyrogallol or derivatives of these classes of compounds. Also, zinc compounds can be used to prevent corrosion on the items to be washed.
- organic redox-active compounds such as di- and trihydric phenols, eg. As hydroquinone, pyrocatechol, hydroxyhydroquinone, gallic acid, phloroglucinol, pyrogallol or derivatives of these classes of compounds.
- zinc compounds can be used to prevent corrosion on the items to be washed.
- detergent tablets contain corrosion inhibitors, they are preferably separated from the bleaching agents. Accordingly, detergent tablets in which at least one phase contains bleach while at least one other phase contains corrosion inhibitors are preferred.
- Preferred anionic surfactants are the salts of alkylsulfosuccinic acid, which are also referred to as sulfosuccinates or as sulfosuccinic acid esters and which are monoesters and / or diesters of sulfosuccinic acid with alcohols, preferably fatty alcohols and in particular ethoxylated fatty alcohols.
- Preferred sulfosuccinates contain C8 to C18 fatty alcohol residues or mixtures of these.
- Particularly preferred sulfosuccinates contain a fatty alcohol residue derived from ethoxylated fatty acids, which in themselves constitute nonionic surfactants (see description below).
- alk (en) ylsuccinic acid having preferably 8 to 18 carbon atoms in the alk (en) yl chain or salts thereof.
- Preferred anionic surfactant mixtures contain combinations of alk (en) ylsulfates, in particular mixtures of saturated and unsaturated fatty alk (en) ylsulfates, and alkylbenzenesulfonates, sulfonated fatty acid glycerol esters and / or ⁇ -sulfofatty acid esters.
- mixtures are preferred here which contain as anionic surfactants alk (en) ylsulfates and alkylbenzenesulfonates, alk (en) ylsulfates and ⁇ -sulfofatty acid methyl esters and / or sulfonated fatty acid glycerol esters.
- anionic surfactants are in particular soaps, preferably in amounts of 0.1 to 5 wt.% Into consideration. Suitable examples are saturated fatty acid soaps, such as the salts of lauric acid, myristic acid, palmitic acid or stearic acid, and in particular soap mixtures derived from natural fatty acids, for example coconut, palm kernel or tallow fatty acids. Particularly preferred are those soap mixtures which are composed of 50 to 100% by weight of saturated C 12 -C 24 fatty acid soaps and 0 to 50% by weight of oleic acid soap.
- the anionic surfactants and soaps can be present in the form of their sodium, potassium or ammonium salts and as soluble salts of organic bases, such as mono-, di- or triethanolamine.
- the anionic surfactants are preferably present in the form of their sodium or potassium salts, in particular in the form of their sodium salts.
- inorganic salts which react alkaline in water.
- These inorganic alkaline salts include in particular bicarbonates, carbonates or mixtures thereof.
- alkali metal carbonate and especially sodium carbonate are used.
- Examples of other customary additives and auxiliaries are enzymes, magnesium silicates, aluminum aluminates, benzotriazole, glycerol, magnesium stearate, polyalkylene glycols, hexametaphosphate and phosphonates.
- Another component of the detergent composition are substances which have an anti-corrosion effect on glass. Glass corrosion protection is also already achieved through the use of the polymer used for the disintegrant, since such a polymer lays a thin film over the glass which protects the glass from corrosion, but other well-known anti-corrosive agents can also be used. Examples of these are metal oxides, such as oxides of zinc, aluminum, tin, magnesium, calcium, strontium, silicon, titanium, zirconium, manganese and lanthanum, or insoluble inorganic zinc compounds, as described in the EP 0 383 482 or zinc or magnesium salts of organic compounds, as described in the DE 101 40 535 are described.
- colorants and fragrances may be added to the automatic dishwashing compositions according to the invention in tablet form in order to improve the aesthetic impression of the resulting products and to provide the consumer with a visual and sensory "typical and unmistakable" product in addition to the performance.
- perfume oils or perfumes individual fragrance compounds, eg.
- ethers, aldehydes, ketones, alcohols and hydrocarbons are used as the synthetic products of the ester type. Fragrance compounds of the ester type are e.g.
- the ethers include, for example, benzyl ethyl ether to the aldehydes z. B.
- the linear alkanals having 8 to 18 carbon atoms citral, citronellal, citronellyloxyacetaldehyde, cyclamen aldehyde, hydroxycitronellal, lilial and bourgeonal, to the ketones z.
- the alcohols include anethole, citronellol, eugenol, geraniol, linalool, phenylethyl alcohol and termpineol; the hydrocarbons mainly include the terpenes such as limonene and pinene.
- mixtures of different fragrances are used, which together produce an attractive fragrance.
- perfume oils may also contain natural fragrance mixtures as are available from vegetable sources, e.g.
- Pine, citrus, jasmine, patchouly, Rose or Ylang-Ylang oil are also suitable.
- the fragrances can be incorporated directly into the moldings of the invention, but it may also be advantageous to apply the fragrances on carriers.
- carrier materials for example, cyclodextrins have been proven, the cyclodextrin-perfume complexes can be additionally coated with other excipients.
- An incorporation of the fragrances as ingredient d) in the detergent components of the invention is possible and leads to a fragrance impression when opening the machine.
- the agents according to the invention can be dyed with suitable dyes.
- Preferred dyes the selection of which presents no difficulty to the skilled person, have a high storage stability and insensitivity to the other ingredients of the agents and against light and no pronounced substantivity to the substrates to be treated with the agents such as glass, ceramic or plastic dishes, not to stain them.
- the coloring of individual phases for optical differentiation is preferred.
- the tablets mentioned in the examples can be used as mono-, double- and triple-phase tablets.
- the individual constituents can be distributed in different regions / phases of the shaped bodies.
- Table 1 Examples of compositions of phosphate-containing dishwashing tablets (all amounts in parts by weight).
- formulation 1 2 3 4 Component: Na tripolyphosphate 35,00 45,00 18,00 60,00 Na carbonate 30.00 20.00 10.00 - Na-bicarbonate - - 10.00 - silicate 4.00 10.00 5.00 - citrate - 5.00 10.00 - Na-percarbonate or Na-perborate 15.00 8.00 20.00 20.00 20.00 TAED 4.00 5.00 2.00 2.00 2.00 nonionic surfactant 2.00 1.00 5.00 2.00 phosphonate 1.00 0.50 2.00 1.00 Acrylate-maleate copolymer 1.00 - 5.00 3.00 enzymes 2.00 1.00 3.00 2.00 Polyethylene glycol 1,500 - 10,000 2.00 3.00 1.00 2.00 Perfume 0.50 0.05 2.00 1.00 explosives 3.50 1.45 7.00 7.00
- Table 2 Examples of compositions of phosphate-free dishwasher tablets (all amounts in parts by weight).
- formulation 5 6 7 Component: Na carbonate 30.00 15.00 - Na-bicarbonate - - 5.00 silicate 4.00 15.00 30.00 citrate 35,00 50,00 20.00 Na-percarbonate or Na-perborate 15.00 8.00 18,00 TAED 4.00 5.00 2.00 nonionic surfactant 2.00 1.00 5.00 phosphonate 1.00 0.50 2.00 Acrylate-maleate copolymer 1.00 - 5.00 enzymes 2.00 1.00 3.00 Polyethylene glycol 1,500 - 10,000 2.00 3.00 1.00 Perfume 0.50 0.05 2.00 explosives 3.50 1.45 7.00
- Basic formulation used for a detergent composition ingredient % w / w sodium tripolyphosphate 37 sodium 40 TAED 12 Enzymes (granules) 6 glycerin 1.2 Polyethylene glycol MW 4000 2 perfume oil 0.05 Alkoxylated (EO / PO) fatty alcohol 1.75 100
- Nilyl XL 16 is a commercially available cellulose-based disintegrant available from FMC corporation USA.
- Supercel is the disintegrant described herein according to the invention containing cellulose and an ⁇ -olefin-maleic acid copolymer (Sokalan CP9) in the form of a "mixed granulate"
- a disintegrant comprising a polymer containing at least one alpha-olefin "(Supercel) disintegrates a dishwashing detergent composition pressed into a tablet much faster than previously available disintegrants even at a low concentration.
- Basic formulation used for a detergent composition ingredient % w / w sodium tripolyphosphate 50 sodium 30.75 Enzymes (granules) 10 Polyethylene glycol MW 200 1.2 Polyethylene glycol MW 4000 1 perfume oil 0.05 Alkoxylated (EO / PO) fatty alcohol 1 94
- a 3-phase tablet is prepared, in which one phase of the detergent composition corresponded, as stated above. This phase represented 20% of the total tablet.
- the total weight of the 3-phase tablet was 20 g.
- the disintegration time of the disintegrant-containing phase after storage was determined. The results are shown in Table 5.
- Table 5 Disintegration times of the phases containing the disintegrant in seconds
- a disintegrating agent (Supercel) according to the invention not only shows a significantly better explosive effect immediately after pressing the tablet than a cellulosic disintegrant available on the market, but still exhibits this better explosive effect even after prolonged storage ,
- Example 4 To the detergent composition of Example 4 is added as disintegrant once 6% w / w Supercel, once 6% w / w Supercel + 2% w / w Sokalan CP 9 in granular form ("CP 9 granules"). Three-phase tablets are compressed as in Example 4, one of the phases consisting of these detergent compositions. This phase accounts for 20% of a 20 g tablet. Again, the decay time of this phase is in Water determined after storage. The results are shown in Table 6.
- Table 6 Disintegration times of the disintegrant-containing phase after storage in seconds
- Table 6 Age of the tablet explosives Supercel Supercel + CP 9 granules 1 day 57 sec 37 sec 4 weeks 56 sec 48 sec 8 weeks 152 sec 94 sec
- detergent compositions were prepared: Formulation A Formulation B ingredient % w / w % w / w sodium tripolyphosphate 74.75 78.25 Enzymes (granules) 11 12 Polyethylene glycol MW 200 1.2 1.2 Polyethylene glycol MW 4000 1.5 1.5 perfume oil 0.05 0.05 Alkoxylated (E0 / P0) 1 1 fatty alcohol Phosphonate granules (HEDP) 1 1 Sokalan® CP9 granules 5 5 Nilyn XL 16 4.5 0
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Detergent Compositions (AREA)
- Medicinal Preparation (AREA)
Claims (6)
- Pastille de lavage pour lave-vaisselle avec ou sans phosphates ayant de une à trois phases, caractérisée en ce qu'en plus des constituants habituels, elle contient des granules comme désintégrants dans au moins une phase, lesquels granules contiennent au moins un polymère comprenant une α-oléfine comme motifs monomères, le polymère est un copolymère d'α-oléfine et de motifs d'un acide bifonctionnel cis, en particulier de motifs d'acide maléique.
- Pastille de lavage pour lave-vaisselle avec ou sans phosphates ayant de une à trois phases, caractérisée en ce qu'en plus des constituants habituels, elle contient des granules comme désintégrants dans au moins une phase, lesquels granules contiennent au moins un polymère comprenant une α-oléfine comme motifs monomères, le polymère est un copolymère d'α-oléfine et de motifs d'un acide bifonctionnel cis, en particulier de motifs d'acide maléique, combiné à de la cellulose pouvant gonfler dans l'eau, à un dérivé cellulosique ou à une substance contenant de la cellulose, est contenu dans les granules.
- Pastille de lavage pour lave-vaisselle selon l'une quelconque des revendications précédentes, caractérisée en ce qu'elle contient des phosphates et en ce qu'elle contient 10 à 75 parties en poids de polyphosphate(s).
- Pastille de lavage pour lave-vaisselle selon la revendication 3, caractérisée en ce qu'elle contient :10 à 75 parties en poids de polyphosphate(s),0 à 60 parties en poids d'autres adjuvants inorganiques,0 à 20 parties en poids d'adjuvants organiques,7 à 20 parties en poids d'agent de blanchiment à base de peroxyde,1 à 10 parties en poids d'activateur(s) de blanchiment,0 à 16 parties en poids de tensioactif(s),0,1 à 10 parties en poids de granules comme désintégrants,2 à 6 parties en poids d'autres adjuvants et additifs habituels.
- Pastille de lavage pour lave-vaisselle selon l'une quelconque des revendications précédentes 1 à 3, caractérisée en ce qu'elle est sans phosphates et en ce qu'elle contient 0 à 50 parties en poids de citrate(s)/acide citrique.
- Pastille de lavage pour lave-vaisselle selon la revendication 5, caractérisée en ce qu'elle contient :0 à 50 parties en poids de citrate(s)/d'acide citrique,0 à 36 parties en poids de silicate,0 à 32 parties en poids de carbonate de sodium/bicarbonate de sodium,0 à 20 parties en poids de bicarbonate,0 à 10 parties en poids d'adjuvants organiques polymères,4 à 18 parties en poids d'agent de blanchiment à base de peroxyde,8,8 à 1 parties en poids d'activateur(s) de blanchiment,0,2 à 16 parties en poids de tensioactif(s),0,1 à 10 parties en poids de granules comme désintégrants,1 à 5 parties en poids d'autres adjuvants et additifs habituels.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES03014785.4T ES2272854T5 (es) | 2003-06-28 | 2003-06-28 | Granulados de alfa-olefina y alfa-olefina/celulosa como disgregantes |
AT03014785T ATE338809T1 (de) | 2003-06-28 | 2003-06-28 | Alpha olefin- und alpha olefin-cellulose granulate als sprengmittel |
EP03014785.4A EP1491621B2 (fr) | 2003-06-28 | 2003-06-28 | Granules d'alpha-oléfine et alpha-oléfine-celluloses, comme désintégrants |
DE50304955T DE50304955D1 (de) | 2003-06-28 | 2003-06-28 | Alpha Olefin- und Alpha Olefin-Cellulose Granulate als Sprengmittel |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03014785.4A EP1491621B2 (fr) | 2003-06-28 | 2003-06-28 | Granules d'alpha-oléfine et alpha-oléfine-celluloses, comme désintégrants |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1491621A1 EP1491621A1 (fr) | 2004-12-29 |
EP1491621B1 EP1491621B1 (fr) | 2006-09-06 |
EP1491621B2 true EP1491621B2 (fr) | 2014-10-01 |
Family
ID=33395899
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP03014785.4A Expired - Lifetime EP1491621B2 (fr) | 2003-06-28 | 2003-06-28 | Granules d'alpha-oléfine et alpha-oléfine-celluloses, comme désintégrants |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1491621B2 (fr) |
AT (1) | ATE338809T1 (fr) |
DE (1) | DE50304955D1 (fr) |
ES (1) | ES2272854T5 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102008060469A1 (de) | 2008-12-05 | 2010-06-10 | Henkel Ag & Co. Kgaa | Maschinelle Geschirrspülmitteltablette |
US8888924B2 (en) | 2012-08-24 | 2014-11-18 | Ecolab Usa Inc. | Freestanding detergent composition not requiring an automated dispenser |
WO2014031743A1 (fr) * | 2012-08-24 | 2014-02-27 | Ecolab Usa Inc. | Composition de détergent autonome ne nécessitant pas de distributeur automatique |
EP4227391A1 (fr) | 2014-03-07 | 2023-08-16 | Ecolab USA Inc. | Composition détergente remplissant à la fois la fonction de nettoyage et de rinçage |
CN105567477A (zh) * | 2015-11-25 | 2016-05-11 | 界首市任寨俊峰山羊养殖家庭农场 | 一种竹羊床专用清洁消毒剂 |
US10851331B2 (en) | 2017-04-27 | 2020-12-01 | Ecolab Usa Inc. | Solid controlled release carbonate detergent compositions |
CN111225970A (zh) | 2017-11-14 | 2020-06-02 | 埃科莱布美国股份有限公司 | 固体控释苛性碱洗涤剂组合物 |
US11518961B2 (en) | 2019-09-27 | 2022-12-06 | Ecolab Usa Inc. | Concentrated 2 in 1 dishmachine detergent and rinse aid |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1043391A1 (fr) † | 1999-03-29 | 2000-10-11 | Stockhausen GmbH & Co. KG | Désintégrant granulaire de haute densité pour comprimé; méthode de préparation et son utilisation |
DE19934704A1 (de) † | 1999-07-23 | 2001-01-25 | Henkel Kgaa | Wasch- und Reinigungsmittelformkörper mit Dispersionsmitteln |
WO2002020708A1 (fr) † | 2000-09-08 | 2002-03-14 | Unilever Plc | Composition trois-en-un de detergent pour laver la vaisselle contenant un acide polycarboxylique |
WO2002034870A1 (fr) † | 2000-10-25 | 2002-05-02 | Unilever Plc | Compositions pour laver la vaisselle |
WO2002064719A1 (fr) † | 2001-02-01 | 2002-08-22 | Basf Aktiengesellschaft | Copolymeres pour empecher la corrosion du verre |
WO2002064720A1 (fr) † | 2001-02-01 | 2002-08-22 | Basf Aktiengesellschaft | Formulations de nettoyants pour empecher la decoloration d'articles en matiere plastique |
WO2002099027A2 (fr) † | 2001-06-05 | 2002-12-12 | Ecolab, Inc. | Composition de nettoyage solide comprenant un composant d'oxygene actif stabilise |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4121307A1 (de) * | 1991-06-27 | 1993-01-07 | Henkel Kgaa | Verfahren zur herstellung stabiler, bifunktioneller, phosphat- und metasilikatfreier niederalkalischer reinigungsmitteltabletten fuer das maschinelle geschirrspuelen |
DE4408718A1 (de) * | 1994-03-15 | 1995-09-21 | Henkel Kgaa | Bruch- und lagerstabile, polyfunktionelle Reinigungstabletten, Verfahren zu ihrer Herstellung und ihre Verwendung |
TR200100092T2 (tr) * | 1998-07-17 | 2001-10-22 | The Procter & Gamble Company | Deterjan tableti |
DK1043388T3 (da) * | 1999-03-29 | 2002-04-02 | Dalli Werke Waesche & Koerperp | Sprængemiddelgranulatholdige opvaskemaskine-rensetabletter |
-
2003
- 2003-06-28 EP EP03014785.4A patent/EP1491621B2/fr not_active Expired - Lifetime
- 2003-06-28 DE DE50304955T patent/DE50304955D1/de not_active Expired - Lifetime
- 2003-06-28 AT AT03014785T patent/ATE338809T1/de not_active IP Right Cessation
- 2003-06-28 ES ES03014785.4T patent/ES2272854T5/es not_active Expired - Lifetime
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1043391A1 (fr) † | 1999-03-29 | 2000-10-11 | Stockhausen GmbH & Co. KG | Désintégrant granulaire de haute densité pour comprimé; méthode de préparation et son utilisation |
DE19934704A1 (de) † | 1999-07-23 | 2001-01-25 | Henkel Kgaa | Wasch- und Reinigungsmittelformkörper mit Dispersionsmitteln |
WO2002020708A1 (fr) † | 2000-09-08 | 2002-03-14 | Unilever Plc | Composition trois-en-un de detergent pour laver la vaisselle contenant un acide polycarboxylique |
WO2002034870A1 (fr) † | 2000-10-25 | 2002-05-02 | Unilever Plc | Compositions pour laver la vaisselle |
WO2002064719A1 (fr) † | 2001-02-01 | 2002-08-22 | Basf Aktiengesellschaft | Copolymeres pour empecher la corrosion du verre |
WO2002064720A1 (fr) † | 2001-02-01 | 2002-08-22 | Basf Aktiengesellschaft | Formulations de nettoyants pour empecher la decoloration d'articles en matiere plastique |
WO2002099027A2 (fr) † | 2001-06-05 | 2002-12-12 | Ecolab, Inc. | Composition de nettoyage solide comprenant un composant d'oxygene actif stabilise |
Also Published As
Publication number | Publication date |
---|---|
EP1491621A1 (fr) | 2004-12-29 |
ES2272854T3 (es) | 2007-05-01 |
ES2272854T5 (es) | 2014-12-10 |
DE50304955D1 (de) | 2006-10-19 |
EP1491621B1 (fr) | 2006-09-06 |
ATE338809T1 (de) | 2006-09-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1004656B1 (fr) | Granulé densifié, procédé pour sa fabrication et son utilisation comme désintégrant dans des corps formés par compactage | |
DE10010760A1 (de) | Mehrphasige Wasch- und Reinigungsmittelformkörper mit nicht-gepreßten Anteilen | |
EP1004661A1 (fr) | Granulé de haute densité, procédé pour sa production, son utilisation en tant que désintégrant pour tablettes | |
EP1524313B1 (fr) | Composition pour lave-vaisselle avec des proprietes de rincage ameliorees | |
WO1996029389A1 (fr) | Procede de fabrication d'un detergent ou nettoyant en poudre | |
DE19723028A1 (de) | Hilfsmittelgranulat für wasch- und reinigungsaktive Formkörper | |
EP1491621B2 (fr) | Granules d'alpha-oléfine et alpha-oléfine-celluloses, comme désintégrants | |
DE10066035B4 (de) | Kompartiment-Hohlkörper | |
DE19851426A1 (de) | Verfahren zur Herstellung mehrphasiger Wasch- und Reinigungsmittelformkörper | |
EP1044256A1 (fr) | Procede de fabrication d'un corps moule detergent pour lave-vaisselle | |
EP1043388B1 (fr) | Comprimés détergents pour le lavage de vaisselle en machine contenant un desintégrant granulaire | |
DE19758181A1 (de) | Geschirrspülmittelformkörper mit Soil-Release-Polymeren | |
DE19934704A1 (de) | Wasch- und Reinigungsmittelformkörper mit Dispersionsmitteln | |
DE19957737A1 (de) | Verpackte Wasch- und Reinigungsmittel-Portion | |
WO1999035232A1 (fr) | Corps moule detergent pour lave-vaisselle a proportions volumiques specifiques | |
EP1141191B1 (fr) | Composes phosphates | |
DE19847281A1 (de) | Wasch- und Reinigungsmittelformkörper mit organischen Oligocarbonsäuren | |
DE20023763U1 (de) | Kompartiment-Hohlkörper | |
DE19930932A1 (de) | Preßverfahren für Wasch- und Reinigungsmitteltabletten | |
DE19851441A1 (de) | Wasch- und Reinigungsmittelformkörper mit Additiven | |
WO2001042417A1 (fr) | Comprimes d'agent de nettoyage multiphases | |
DE19908022A1 (de) | Lagerstabile Wasch- und Reinigungsmittelformkörper | |
DE102004020009A1 (de) | Wasch- und Reinigungsmittelformkörper mit Celluloseetherderivat | |
WO2001032821A1 (fr) | Portion de produit de lavage ou de nettoyage contenant un agent de blanchiment | |
DE20023760U1 (de) | Kompartiment-Hohlkörper |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK |
|
17P | Request for examination filed |
Effective date: 20050615 |
|
AKX | Designation fees paid |
Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CZ Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20060906 Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20060906 Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20060906 Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20060906 Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20060906 Ref country code: IE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20060906 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20060906 Ref country code: IT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT;WARNING: LAPSES OF ITALIAN PATENTS WITH EFFECTIVE DATE BEFORE 2007 MAY HAVE OCCURRED AT ANY TIME BEFORE 2007. THE CORRECT EFFECTIVE DATE MAY BE DIFFERENT FROM THE ONE RECORDED. Effective date: 20060906 |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D Free format text: NOT ENGLISH |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D Free format text: LANGUAGE OF EP DOCUMENT: GERMAN |
|
REF | Corresponds to: |
Ref document number: 50304955 Country of ref document: DE Date of ref document: 20061019 Kind code of ref document: P |
|
GBT | Gb: translation of ep patent filed (gb section 77(6)(a)/1977) |
Effective date: 20061026 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20061206 Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20061206 Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20061206 |
|
ET | Fr: translation filed | ||
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20070219 |
|
NLV1 | Nl: lapsed or annulled due to failure to fulfill the requirements of art. 29p and 29m of the patents act | ||
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FD4D |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FG2A Ref document number: 2272854 Country of ref document: ES Kind code of ref document: T3 |
|
PLBI | Opposition filed |
Free format text: ORIGINAL CODE: 0009260 |
|
PLAX | Notice of opposition and request to file observation + time limit sent |
Free format text: ORIGINAL CODE: EPIDOSNOBS2 |
|
26 | Opposition filed |
Opponent name: HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN Effective date: 20070604 |
|
PLBB | Reply of patent proprietor to notice(s) of opposition received |
Free format text: ORIGINAL CODE: EPIDOSNOBS3 |
|
BERE | Be: lapsed |
Owner name: DALLI-WERKE G.M.B.H. & CO. KG Effective date: 20070630 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20070630 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20070630 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20070630 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20070630 Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20061207 |
|
PLAB | Opposition data, opponent's data or that of the opponent's representative modified |
Free format text: ORIGINAL CODE: 0009299OPPO |
|
R26 | Opposition filed (corrected) |
Opponent name: HENKEL AG & CO. KGAA Effective date: 20070604 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20060906 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20070628 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20070628 Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20060906 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: HU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20070307 Ref country code: TR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20060906 |
|
APBM | Appeal reference recorded |
Free format text: ORIGINAL CODE: EPIDOSNREFNO |
|
APBP | Date of receipt of notice of appeal recorded |
Free format text: ORIGINAL CODE: EPIDOSNNOA2O |
|
APAH | Appeal reference modified |
Free format text: ORIGINAL CODE: EPIDOSCREFNO |
|
APBM | Appeal reference recorded |
Free format text: ORIGINAL CODE: EPIDOSNREFNO |
|
APBP | Date of receipt of notice of appeal recorded |
Free format text: ORIGINAL CODE: EPIDOSNNOA2O |
|
APBQ | Date of receipt of statement of grounds of appeal recorded |
Free format text: ORIGINAL CODE: EPIDOSNNOA3O |
|
APBQ | Date of receipt of statement of grounds of appeal recorded |
Free format text: ORIGINAL CODE: EPIDOSNNOA3O |
|
APBU | Appeal procedure closed |
Free format text: ORIGINAL CODE: EPIDOSNNOA9O |
|
PLAY | Examination report in opposition despatched + time limit |
Free format text: ORIGINAL CODE: EPIDOSNORE2 |
|
PLBC | Reply to examination report in opposition received |
Free format text: ORIGINAL CODE: EPIDOSNORE3 |
|
PLAY | Examination report in opposition despatched + time limit |
Free format text: ORIGINAL CODE: EPIDOSNORE2 |
|
PLBC | Reply to examination report in opposition received |
Free format text: ORIGINAL CODE: EPIDOSNORE3 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R082 Ref document number: 50304955 Country of ref document: DE Representative=s name: FLEISCHER, ENGELS & PARTNER MBB, PATENTANWAELT, DE |
|
PUAH | Patent maintained in amended form |
Free format text: ORIGINAL CODE: 0009272 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: PATENT MAINTAINED AS AMENDED |
|
27A | Patent maintained in amended form |
Effective date: 20141001 |
|
AK | Designated contracting states |
Kind code of ref document: B2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R102 Ref document number: 50304955 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R102 Ref document number: 50304955 Country of ref document: DE Effective date: 20141001 |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: DC2A Ref document number: 2272854 Country of ref document: ES Kind code of ref document: T5 Effective date: 20141210 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 14 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 15 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 16 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20200604 Year of fee payment: 18 Ref country code: FR Payment date: 20200619 Year of fee payment: 18 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20200625 Year of fee payment: 18 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: ES Payment date: 20200824 Year of fee payment: 18 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20200625 Year of fee payment: 18 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R119 Ref document number: 50304955 Country of ref document: DE |
|
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20210628 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20210628 Ref country code: DE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20220101 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20210630 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20210628 |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FD2A Effective date: 20220826 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20210629 |