EP1470094A1 - Procede de production de derives de toluene - Google Patents

Procede de production de derives de toluene

Info

Publication number
EP1470094A1
EP1470094A1 EP03701527A EP03701527A EP1470094A1 EP 1470094 A1 EP1470094 A1 EP 1470094A1 EP 03701527 A EP03701527 A EP 03701527A EP 03701527 A EP03701527 A EP 03701527A EP 1470094 A1 EP1470094 A1 EP 1470094A1
Authority
EP
European Patent Office
Prior art keywords
hydrogenation
catalyst
weight
components
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03701527A
Other languages
German (de)
English (en)
Inventor
Nils Bottke
Rolf-Hartmuth Fischer
Thomas NÖBEL
Markus Rösch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of EP1470094A1 publication Critical patent/EP1470094A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C07C1/20—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms
    • C07C1/22—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only oxygen atoms as heteroatoms by reduction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
    • B01J23/76—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups B01J23/02 - B01J23/36
    • B01J23/84—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups B01J23/02 - B01J23/36 with arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
    • B01J23/889—Manganese, technetium or rhenium
    • B01J23/8892—Manganese
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/002—Mixed oxides other than spinels, e.g. perovskite
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
    • B01J23/72—Copper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
    • B01J23/74—Iron group metals
    • B01J23/755—Nickel
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
    • B01J23/76—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups B01J23/02 - B01J23/36
    • B01J23/84—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups B01J23/02 - B01J23/36 with arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
    • B01J23/85—Chromium, molybdenum or tungsten
    • B01J23/88—Molybdenum
    • B01J23/885—Molybdenum and copper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
    • B01J23/76—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups B01J23/02 - B01J23/36
    • B01J23/84—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups B01J23/02 - B01J23/36 with arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
    • B01J23/889—Manganese, technetium or rhenium
    • B01J23/8898—Manganese, technetium or rhenium containing also molybdenum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2523/00—Constitutive chemical elements of heterogeneous catalysts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2523/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00
    • C07C2523/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of the iron group metals or copper
    • C07C2523/72—Copper
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2523/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00
    • C07C2523/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of the iron group metals or copper
    • C07C2523/74—Iron group metals
    • C07C2523/75—Cobalt
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2523/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00
    • C07C2523/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of the iron group metals or copper
    • C07C2523/74—Iron group metals
    • C07C2523/755—Nickel

Definitions

  • the present invention relates to a process for the preparation of toluene derivatives I,
  • R 1 , R 2 and R 3 independently of one another denote hydrogen, halogen, Ci-Cg-alkyl, hydroxyl or Ci-Cg-alkoxy, by hydrogenation of benzaldehydes and / or benzyl alcohols of the formula II,
  • EP 606072 reports on the hydrogenation of benzaldehydes on shaped titanium oxide containing a platinum group metal.
  • the starting materials are used in only 1% aqueous or ethanolic solution and thus in high dilution.
  • the hydrogenation proceeds with low turnover and extremely low selectivity.
  • Nuclear hydrogenated or demethylated benzenes occur as by-products.
  • the object was to develop a process for the preparation of substituted toluene compounds which can be carried out with high yield and selectivity and which avoids the disadvantages mentioned. Above all, expensive precious metal catalysts, chromium-containing catalysts and corrosive solvents should be avoided. Side reactions such as the core hydrogenation to cyclohexane derivatives, the decarbonylation of the aldehyde function or the elimination of substituents such as alkoxy or halogen on the phenyl ring should be prevented as completely as possible.
  • R 1, R 2 and R 3 are independently hydrogen, halogen, Ci-C ß alkyl, hydroxyl, or C ⁇ -C 6 -alkoxy, by hydrogenation of benzaldehydes and / or benzyl alcohols of the formula II, C 6 alkyl] 2 -C 6 alkyl with hydrogen in the presence of a catalyst, characterized in that the catalyst is composed as follows:
  • (b) 0 to 50% by weight of one or more metals and / or one or more oxides, hydroxides or salts of a metal selected from the group consisting of platinum, rhodium, iron, silver, molybdenum, tungsten, manganese, rhenium , Zinc, cadmium, lead, aluminum, zircon, tin, phosphorus, silicon, arsenic,
  • Preferred catalysts are those in which component (a) makes up 5 to 100% by weight. Catalysts which contain component (a) in 40 to 99% by weight are particularly preferred.
  • catalysts are preferred in which component (b) is contained in 0 to 50% by weight and in particular in 1 to 40% by weight.
  • Preferred catalysts contain as component (b) at least one metal oxide, hydroxide or salt selected from the group consisting of platinum, rhodium, iron, silver, molybdenum, tungsten, manganese, rhenium, zinc, cadmium, lead, aluminum, zirconium, tin, phosphorus , Silicon, arsenic, antimony, bismuth and rare earth metals.
  • catalysts contain as component (b) at least one metal oxide, hydroxide or salt selected from the group consisting of aluminum, silicon, zirconium, molybdenum, manganese and phosphorus.
  • Oxides or salts of alkali metals and alkaline earth metals selected from the group consisting of lithium, potassium, cesium, magnesium and calcium and particularly preferably sodium are preferably used as component (c) in the catalysts according to the invention.
  • the catalysts can be used as homogeneous catalysts in dissolved form or as heterogeneous catalysts. Both
  • Q heterogeneous catalysts can be supported catalysts, unsupported catalysts or Raney catalysts, which are used in fixed arrangement, in suspended or in swirled form.
  • Support materials include, for example, oxides such as aluminum oxide, silicon dioxide, aluminum silicates, lanthanum oxide, titanium
  • the heterogeneous catalysts are generally prepared in such a way that precursors of components (a) are optionally added.
  • Supported catalysts are generally also obtainable by impregnating the support with a solution of components (a) and optionally (b) and / or (c), it being possible to add the individual components simultaneously or in succession, or by adding components (a ) and optional
  • binders can be used in catalyst manufacture.
  • Suitable precursors of component (a) are generally readily water-soluble salts of the aforementioned metals, such as nitrates, chlorides, acetates, formates and sulfates, preferably nitrates.
  • Suitable precursors for components (b) are generally readily water-soluble salts or complex salts of the metals mentioned above such as 40 nitrates, chlorides, acetates, formates and sulfates, preferably nitrates.
  • Suitable precursors for components (c) are generally readily water-soluble salts of the abovementioned alkali metals and alkaline earth metals 4 5 such as hydroxides, carbonates, nitrates, chlorides, acetates, research miate and sulfates, preferably hydroxides and carbonates.
  • the precipitation is generally carried out from aqueous solutions, optionally by adding precipitation reagents, by changing the pH or by changing the temperature.
  • the catalyst pre-mass obtained in this way is usually pre-dried at temperatures in the range from 80 to 150 ° C., preferably from 80 to 120 ° C.
  • the calcination is usually carried out at temperatures in the range from 150 to 500 ° C., preferably from 200 to 450 ° C., in a gas stream from air or nitrogen.
  • the catalyst surface is passivated, which is usually carried out at temperatures in the range from 20 to 80, preferably from 25 to 35 ° C. by means of oxygen-nitrogen mixtures such as air.
  • the calcined and optionally passivated catalyst mass obtained is generally subjected to a reducing atmosphere (“activation”), for example by being at a temperature in the range from 100 to 500 ° C., preferably from 150 to 400 ° C., from 2 to 60 h exposed to a gas stream containing free hydrogen.
  • activation for example by being at a temperature in the range from 100 to 500 ° C., preferably from 150 to 400 ° C., from 2 to 60 h exposed to a gas stream containing free hydrogen.
  • the gas stream preferably consists of 20 to 100% by volume of hydrogen and 0 to 50% by volume of an inert gas such as nitrogen.
  • the catalysts of the invention are notable for high activity and enable high throughputs with practically complete conversion.
  • the hydrogenation can be carried out batchwise, but in particular continuously. Continuous operation can be carried out in the sump or trickle mode, in the gas or in the liquid phase.
  • the starting materials of the formulas Ila and Ilb can be obtained by the processes described in the literature cited at the beginning.
  • the compounds Ila and Ilb can in substance, for. B. in the gas phase or as a melt. In some cases it has proven advantageous to add a solvent.
  • Suitable solvents are those which have a sufficient solvency for the starting materials II and the target products I and which are stable under the hydrogenation conditions.
  • solvents are ethers such as tetrahydrofuran, dioxane, tetrahydropyran, polyethylene glycol dialkyl ether or polyethylene glycol monoalkyl ether, water, alcohols such as methanol, ethanol, tert. -Butanol, cyclohexanol, alkylbenzenes such as toluene or xylenes, phenols such as pyrocatechol, resorcinol, hydroquinone, pyrogallol or alkyl ethers of these phenols. Mixtures of these solvents can also be used.
  • Preferred solvents are tetrahydrofuran, dioxane, tetrahydropyran, polyethylene glycol dialkyl ether, polyethylene glycol onoalkyl ether, alkylbenzenes, water and alcohols or mixtures of these compounds.
  • Ether or ether / water mixtures are particularly suitable.
  • alcohols and alcohol / water mixtures in particular methanol and ethanol / water mixtures.
  • the hydrogenation is carried out in the gas phase without using a solvent.
  • Hydrogenation is carried out at from 20 to 280 ° C. and from 1 to 300 bar, preferably at from 100 to 260 ° C. and from 20 to 250 bar.
  • the hydrogen used for the hydrogenation is generally used in a relatively large stoichiometric excess relative to the starting compound II.
  • the hydrogen can be returned to the reaction as cycle gas.
  • the hydrogen is generally used in a technically pure manner.
  • Mixing inert gases, e.g. B. nitrogen does not interfere with the course of the reaction.
  • the compounds I which can be prepared by the hydrogenation according to the invention represent valuable intermediates which can be used for the production of pharmaceutical products, fine chemicals and crop protection agents.
  • the invention is explained in more detail below on the basis of exemplary embodiments.
  • the percentages mean percentages by weight.
  • Catalyst A 60% by weight CuO; 40% by weight Al 2 0 3;
  • Catalyst B 65.4 wt% CoO; 20.2 wt% CuO; 8.3% by weight Mn 3 0 4 ;
  • Catalyst C 74.0% by weight NiO; 2.2% by weight Mo0 3 ; 23.8 wt% CuO; on
  • Catalyst D 77.7% by weight NiO, 13.6% by weight Si0 2 , 5.8% by weight Al 2 0 3 , 4.7% by weight Zr0 2 .
  • the temperature was raised by about 20 ° C. per hour from room temperature until a temperature of 290 ° C. was reached, starting from room temperature. Now the nitrogen was exchanged for hydrogen within 6 hours. For this purpose, the hydrogen content was increased by 50 l / h per hour and the nitrogen content was reduced by 50 l / h at the same time.
  • the reactor temperature was raised to 300-310 ° C and maintained at 300 l / h of hydrogen for 48 hours.
  • the catalyst was removed under argon and stored under tetraethylene glycol dimethyl ether.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

L'invention concerne la production de dérivés de toluène de la formule (I) où R<1>, R<2> et R<3> représentent indépendamment un hydrogène, halogène, alkyle C1-C6, hydroxyle ou alcoxy C1-C6, par hydrogénation de benzaldéhydes et/ou d'alcools benzyliques de la formule (II) où IIa: X=CHO X=CH[OC1-C6-alkyle]2, IIb: X=CH2-OH X=CH2OC1-C6-alkyle, avec de l'hydrogène en présence d'un catalyseur qui est défini plus précisément dans la description.
EP03701527A 2002-01-24 2003-01-20 Procede de production de derives de toluene Withdrawn EP1470094A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10202837 2002-01-24
DE10202837 2002-01-24
PCT/EP2003/000488 WO2003062174A1 (fr) 2002-01-24 2003-01-20 Procede de production de derives de toluene

Publications (1)

Publication Number Publication Date
EP1470094A1 true EP1470094A1 (fr) 2004-10-27

Family

ID=27588050

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03701527A Withdrawn EP1470094A1 (fr) 2002-01-24 2003-01-20 Procede de production de derives de toluene

Country Status (14)

Country Link
US (1) US7230141B2 (fr)
EP (1) EP1470094A1 (fr)
JP (1) JP2005515248A (fr)
KR (1) KR20040077781A (fr)
CN (1) CN1257870C (fr)
AR (1) AR038314A1 (fr)
BR (1) BR0306939A (fr)
CA (1) CA2473936A1 (fr)
EA (1) EA007065B1 (fr)
MX (1) MXPA04006744A (fr)
PL (1) PL372164A1 (fr)
UA (1) UA78982C2 (fr)
WO (1) WO2003062174A1 (fr)
ZA (1) ZA200406665B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101531574B (zh) * 2009-04-14 2012-07-25 大连理工大学 一种制备3,4,5-三甲氧基甲苯的方法
WO2012059387A1 (fr) * 2010-11-02 2012-05-10 Basf Se Procédé de production d'un phénylcyclohexane
CN102746100A (zh) * 2011-04-20 2012-10-24 中国石油化工股份有限公司 制备异丙苯的方法
KR101930087B1 (ko) * 2011-07-26 2018-12-18 에스케이이노베이션 주식회사 방향족 카르복시산 및/또는 방향족 카르복시산 알킬 에스테르 제조 공정에서 발생하는 부산물로부터 방향족 탄화수소 제조방법
US9259715B2 (en) 2012-10-17 2016-02-16 Archer Daniels Midland Company Hydrogenolysis catalysts and uses thereof
US9205412B2 (en) 2013-03-01 2015-12-08 Clariant Corporation Catalyst for polyol hydrogenolysis
RU2625656C1 (ru) * 2016-02-17 2017-07-18 Общество с ограниченной ответственностью "Научно-производственное объединение "НИИПАВ" (ООО НПО "НИИПАВ") Способ получения алкилдиметиламинов

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR678954A (fr) 1928-11-19 1930-04-07 Expl Des Matieres Organiques S Procédé pour la transformation des crésols en benzène et méthylbenzène en présence d'un catalyseur de réduction ou d'hydrogénation, avec ou sans addition de gazhydrogène
DE904529C (de) 1942-08-07 1954-02-18 Bayer Ag Verwendung eines Nickel, Chromoxyd und Aluminiumoxyd enthaltenden Hydrierungskatalysators
US2682562A (en) * 1951-05-10 1954-06-29 Us Interior Reduction of aromatic carbinols
EP0053884A1 (fr) * 1980-11-27 1982-06-16 Johnson Matthey Public Limited Company Supports de catalyseur interstitiel tridimensionnel, sa fabrication et son utilisation
DE4300297C2 (de) * 1993-01-08 1998-01-29 Degussa Verfahren zur selektiven katalytischen Hydrierung der Carbonylgruppe von 4-Carboxylbenzaldehyd

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO03062174A1 *

Also Published As

Publication number Publication date
PL372164A1 (en) 2005-07-11
EA007065B1 (ru) 2006-06-30
WO2003062174A1 (fr) 2003-07-31
ZA200406665B (en) 2006-06-28
CN1257870C (zh) 2006-05-31
AR038314A1 (es) 2005-01-12
MXPA04006744A (es) 2005-06-08
CA2473936A1 (fr) 2003-07-31
US20050032627A1 (en) 2005-02-10
US7230141B2 (en) 2007-06-12
CN1622926A (zh) 2005-06-01
EA200400876A1 (ru) 2004-12-30
KR20040077781A (ko) 2004-09-06
BR0306939A (pt) 2004-12-14
JP2005515248A (ja) 2005-05-26
UA78982C2 (en) 2007-05-10

Similar Documents

Publication Publication Date Title
EP0324984B1 (fr) Procédé de préparation d&#39;un mélange de cyclohexylamine et dicyclohexylamine en utilisant un catalyseur à base de ruthénium
EP2513037B1 (fr) Procede de preparation d&#39;ethanolamines superieures
EP2576533B1 (fr) Procédé de préparation de tétrahydropyranols substitués en position 2
EP0324983B1 (fr) Catalyseur supporté à base de ruthénium, sa préparation et son utilisation dans la préparation de cyclohexylamine et de dicyclohexylamine éventuellement substituées
EP0394842B1 (fr) Catalyseur pour l&#39;hydrogénation de composés aliphatiques insaturés
EP2379478B1 (fr) Procédé continu de production de cyclohexylméthanols substitués
EP1050523B1 (fr) Procédé pour l&#39;addition de composés contenant un groupe hydroxyle sur les alcines ou les allènes utilisant un catalyseur hémimorphite
CH624311A5 (fr)
EP1470094A1 (fr) Procede de production de derives de toluene
WO2008064991A1 (fr) Procédé de production de 3-alcoxypropan-1-ols
EP0013385B1 (fr) Procédé pour la préparation de composés carbonylés aliphatiques
EP0891960B1 (fr) Procédé pour la préparation de monoéthers de pyrocatéchine et de pyrocatéchines
EP0081647B1 (fr) Procédé d&#39;ortho-méthylation de composés phénoliques
DE19739716A1 (de) Verfahren zur Herstellung von ungesättigten Ketonen
EP1385806B1 (fr) Procede a une etape pour produire le trimethoxytoluene
WO1998058894A1 (fr) Procede de fabrication d&#39;ethers enoliques
DE102016116347A1 (de) Verfahren zur gleichzeitigen und kontinuierlichen herstellung von cyclohexanon und hydrozimtaldehyd aus cyclohexanol und zimtaldehyd
EP1505051A1 (fr) Procédé pour la préparation de 2,2,6-triméthylcyclohexan-1-one
DE10156685A1 (de) Verfahren zur Herstellung von Monoisopropylamin
WO2004046073A1 (fr) Procede de production d&#39;ethers
DE2830456A1 (de) Verfahren zur herstellung von anthron

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20040824

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO

RIN1 Information on inventor provided before grant (corrected)

Inventor name: ROESCH, MARKUS

Inventor name: NOEBEL, THOMAS

Inventor name: FISCHER, ROLF-HARTMUTH

Inventor name: BOTTKE, NILS

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN

18W Application withdrawn

Effective date: 20070530