EP1287162A2 - Ermittlung des genexpressionsprofils bei entzündlichen darmerkrankungen - Google Patents

Ermittlung des genexpressionsprofils bei entzündlichen darmerkrankungen

Info

Publication number
EP1287162A2
EP1287162A2 EP00988479A EP00988479A EP1287162A2 EP 1287162 A2 EP1287162 A2 EP 1287162A2 EP 00988479 A EP00988479 A EP 00988479A EP 00988479 A EP00988479 A EP 00988479A EP 1287162 A2 EP1287162 A2 EP 1287162A2
Authority
EP
European Patent Office
Prior art keywords
gene
ibd
nucleic acid
genes
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00988479A
Other languages
English (en)
French (fr)
Inventor
Shukti Chakravarti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Case Western Reserve University
Original Assignee
Case Western Reserve University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Case Western Reserve University filed Critical Case Western Reserve University
Priority to EP10182252A priority Critical patent/EP2319939A3/de
Publication of EP1287162A2 publication Critical patent/EP1287162A2/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP00988479A 1999-10-21 2000-10-23 Ermittlung des genexpressionsprofils bei entzündlichen darmerkrankungen Withdrawn EP1287162A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP10182252A EP2319939A3 (de) 1999-10-21 2000-10-23 Genexpressionsprofil für entzündliche Darmerkrankung

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16083599P 1999-10-21 1999-10-21
US160835P 1999-10-21
PCT/US2000/041457 WO2001029269A2 (en) 1999-10-21 2000-10-23 Gene expression profiling of inflammatory bowel disease

Publications (1)

Publication Number Publication Date
EP1287162A2 true EP1287162A2 (de) 2003-03-05

Family

ID=22578660

Family Applications (2)

Application Number Title Priority Date Filing Date
EP00988479A Withdrawn EP1287162A2 (de) 1999-10-21 2000-10-23 Ermittlung des genexpressionsprofils bei entzündlichen darmerkrankungen
EP10182252A Withdrawn EP2319939A3 (de) 1999-10-21 2000-10-23 Genexpressionsprofil für entzündliche Darmerkrankung

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP10182252A Withdrawn EP2319939A3 (de) 1999-10-21 2000-10-23 Genexpressionsprofil für entzündliche Darmerkrankung

Country Status (5)

Country Link
EP (2) EP1287162A2 (de)
AU (1) AU784861B2 (de)
CA (1) CA2356207C (de)
IL (1) IL143936A0 (de)
WO (1) WO2001029269A2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6525018B1 (en) 1999-05-17 2003-02-25 The General Hospital Corp. Treating eye disorders using intestinal trefoil proteins
US6960439B2 (en) 1999-06-28 2005-11-01 Source Precision Medicine, Inc. Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
US7538082B2 (en) 2001-04-24 2009-05-26 The General Hospital Corporation Methods and compositions for treating oral and esophageal lesions
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
CA2842429A1 (en) * 2001-10-19 2003-05-01 Genentech, Inc. Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders
KR20040064275A (ko) 2001-11-09 2004-07-16 소스 프리시전 메디슨, 인코포레이티드 유전자 발현 프로파일을 이용한 질병의 동정, 모니터링,치료 및 생물학적 상태의 확인
EP1498486A4 (de) * 2002-03-29 2005-08-03 Prec System Science Co Ltd Nukleinsäurebibliothek und proteinbibliothek
AU2003247303A1 (en) * 2002-07-17 2004-02-02 Index Pharmaceuticals Ab Antisense compounds, methods and compositions for treating ngal-related inflammatory disorders
EP1531833A1 (de) * 2002-07-18 2005-05-25 Index Pharmaceuticals AB Antisense-verbindungen, verfahren und zusammensetzungen zur behandlung von entz ndlichen erkrankungen im zusammenhang mit mmp-12
DE10328813B4 (de) * 2003-06-20 2006-04-13 Epigenomics Ag Verfahren zur Untersuchung von Cytosin-Methylierungen in DNA-Sequenzen mittels triplexbildender Oligomere
WO2006017647A1 (en) 2004-08-03 2006-02-16 Transtech Pharma, Inc. Rage fusion proteins and methods of use
ES2326708B1 (es) * 2005-10-05 2010-09-30 Progenika Biopharma, S.A. Metodos y productos para genotipado in vitro.
US8153363B2 (en) 2005-01-13 2012-04-10 Progenika Biopharma S.A. Methods and products for in vitro genotyping
JP2008526249A (ja) * 2005-01-13 2008-07-24 プロジェニカ・バイオファーマ・エス・アー invitro遺伝子タイピングのための方法および製品
AU2006254971A1 (en) * 2005-06-06 2006-12-14 Wyeth Expression profiles of peripheral blood mononuclear cells for inflammatory bowel diseases
EP2021474A2 (de) 2006-05-05 2009-02-11 Transtech Pharma, Inc. Rage-fusionsproteine, formulierungen daraus und verfahren zu ihrer verwendung
WO2008048986A2 (en) * 2006-10-17 2008-04-24 Children's Hospital Medical Center Gene array technique for predicting response in inflammatory bowel diseases
WO2008147869A2 (en) * 2007-05-22 2008-12-04 Centocor, Inc. Markers and methods for assessing and treating crohn's disease and related disorders
PL2158210T3 (pl) 2007-06-14 2016-08-31 Galactica Pharmaceuticals Inc Białka fuzyjne RAGE
JP2011509071A (ja) * 2007-11-29 2011-03-24 ジェネンテック, インコーポレイテッド 炎症性腸疾患のための遺伝子発現マーカー
US7879553B2 (en) 2008-03-14 2011-02-01 Exagen Diagnostics, Inc. Biomarkers for inflammatory bowel disease and irritable bowel syndrome
RU2011142230A (ru) 2009-04-20 2013-05-27 Пфайзер Инк. Контроль гликозилирования белка и композиции и способы, касающиеся этого
ES2356458B1 (es) * 2009-09-11 2012-01-23 Progenika Biopharma, S.A. Métodos y productos para genotipado in vitro de variaciones génicas humanas asociadas a reacciones adversas a fármacos.
US9797912B2 (en) 2013-06-28 2017-10-24 Newsouth Innovations Pty Limited Diagnostic method for inflammatory bowel disease
WO2019008093A1 (en) * 2017-07-07 2019-01-10 University Of Copenhagen MARKERS FOR DIAGNOSING INFLAMMATORY INTESTINAL DISEASES

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4902505A (en) 1986-07-30 1990-02-20 Alkermes Chimeric peptides for neuropeptide delivery through the blood-brain barrier
CA1319101C (en) 1986-09-03 1993-06-15 Marta Iris Sabara Rotavirus nucleocapsid protein with or without binding peptides as immunologic carriers for macromolecules
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US5116742A (en) 1986-12-03 1992-05-26 University Patents, Inc. RNA ribozyme restriction endoribonucleases and methods
US4904582A (en) 1987-06-11 1990-02-27 Synthetic Genetics Novel amphiphilic nucleic acid conjugates
US5254678A (en) 1987-12-15 1993-10-19 Gene Shears Pty. Limited Ribozymes
US5176996A (en) 1988-12-20 1993-01-05 Baylor College Of Medicine Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use
US5256775A (en) 1989-06-05 1993-10-26 Gilead Sciences, Inc. Exonuclease-resistant oligonucleotides
US5144019A (en) 1989-06-21 1992-09-01 City Of Hope Ribozyme cleavage of HIV-I RNA
US5225337A (en) 1989-09-25 1993-07-06 Innovir Laboratories, Inc. Ribozyme compositions and methods for use
US5264564A (en) 1989-10-24 1993-11-23 Gilead Sciences Oligonucleotide analogs with novel linkages
US5858659A (en) 1995-11-29 1999-01-12 Affymetrix, Inc. Polymorphism detection
US5498531A (en) 1993-09-10 1996-03-12 President And Fellows Of Harvard College Intron-mediated recombinant techniques and reagents
US5631734A (en) 1994-02-10 1997-05-20 Affymetrix, Inc. Method and apparatus for detection of fluorescently labeled materials
US5578832A (en) 1994-09-02 1996-11-26 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
US5571639A (en) 1994-05-24 1996-11-05 Affymax Technologies N.V. Computer-aided engineering system for design of sequence arrays and lithographic masks
US5556752A (en) 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
US6974666B1 (en) 1994-10-21 2005-12-13 Appymetric, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US5599695A (en) 1995-02-27 1997-02-04 Affymetrix, Inc. Printing molecular library arrays using deprotection agents solely in the vapor phase
AU700952B2 (en) 1995-06-07 1999-01-14 Pioneer Hi-Bred International, Inc. PCR-based cDNA subtractive cloning method
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5654173A (en) 1996-08-23 1997-08-05 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
AU707636C (en) 1995-11-23 2003-01-16 Cancer Research Campaign Technology Limited Materials and methods relating to the identification and sequencing of the BRCA2 cancer susceptibility gene and uses thereof
JP2002515738A (ja) 1996-01-23 2002-05-28 アフィメトリックス,インコーポレイティド 核酸分析法
EP0937159A4 (de) 1996-02-08 2004-10-20 Affymetrix Inc Speziesbestimmung und phenotypische charakterisierung von mikroorganismen auf der basis eines chips
US6458530B1 (en) 1996-04-04 2002-10-01 Affymetrix Inc. Selecting tag nucleic acids
US6228585B1 (en) * 1998-09-04 2001-05-08 Washington University Gene markers for chronic mucosal injury

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO0129269A3 *

Also Published As

Publication number Publication date
EP2319939A3 (de) 2012-09-26
AU784861B2 (en) 2006-07-06
CA2356207C (en) 2012-10-09
CA2356207A1 (en) 2001-04-26
IL143936A0 (en) 2002-04-21
EP2319939A2 (de) 2011-05-11
AU2468501A (en) 2001-04-30
WO2001029269A2 (en) 2001-04-26
WO2001029269A3 (en) 2002-12-05

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