EP1222199A4 - Complexe de recepteurs peptidiques n-formyle et d'agents de modification du mecanisme de signalisation de la proteine kinase g - Google Patents

Complexe de recepteurs peptidiques n-formyle et d'agents de modification du mecanisme de signalisation de la proteine kinase g

Info

Publication number
EP1222199A4
EP1222199A4 EP00970817A EP00970817A EP1222199A4 EP 1222199 A4 EP1222199 A4 EP 1222199A4 EP 00970817 A EP00970817 A EP 00970817A EP 00970817 A EP00970817 A EP 00970817A EP 1222199 A4 EP1222199 A4 EP 1222199A4
Authority
EP
European Patent Office
Prior art keywords
protein kinase
receptor complex
modification agent
signal pathway
peptide receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00970817A
Other languages
German (de)
English (en)
Other versions
EP1222199A1 (fr
Inventor
James A Clagett
Craig Palmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mowycal Lending LLC
Original Assignee
Histatek LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Histatek LLC filed Critical Histatek LLC
Publication of EP1222199A1 publication Critical patent/EP1222199A1/fr
Publication of EP1222199A4 publication Critical patent/EP1222199A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
EP00970817A 1999-10-15 2000-10-12 Complexe de recepteurs peptidiques n-formyle et d'agents de modification du mecanisme de signalisation de la proteine kinase g Withdrawn EP1222199A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15967799P 1999-10-15 1999-10-15
US159677P 1999-10-15
PCT/US2000/028183 WO2001029069A1 (fr) 1999-10-15 2000-10-12 Complexe de recepteurs peptidiques n-formyle et d'agents de modification du mecanisme de signalisation de la proteine kinase g

Publications (2)

Publication Number Publication Date
EP1222199A1 EP1222199A1 (fr) 2002-07-17
EP1222199A4 true EP1222199A4 (fr) 2003-03-12

Family

ID=22573520

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00970817A Withdrawn EP1222199A4 (fr) 1999-10-15 2000-10-12 Complexe de recepteurs peptidiques n-formyle et d'agents de modification du mecanisme de signalisation de la proteine kinase g

Country Status (16)

Country Link
EP (1) EP1222199A4 (fr)
JP (1) JP2004507441A (fr)
KR (1) KR20020057972A (fr)
CN (1) CN100497374C (fr)
AU (1) AU8014200A (fr)
BR (1) BR0014742A (fr)
CA (1) CA2387559A1 (fr)
CZ (1) CZ20021342A3 (fr)
EA (1) EA200200451A1 (fr)
HU (1) HUP0203688A2 (fr)
IL (1) IL149125A0 (fr)
MX (1) MXPA02003782A (fr)
NO (1) NO20021732L (fr)
PL (1) PL356096A1 (fr)
WO (1) WO2001029069A1 (fr)
ZA (1) ZA200202937B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030220258A1 (en) 2001-12-21 2003-11-27 Robbert Benner Treatment of ischemic events
US6844315B2 (en) 1998-05-20 2005-01-18 Erasmus Universiteit Rotterdam Immunoregulator
EP1138692A1 (fr) 2000-03-29 2001-10-04 Erasmus Universiteit Rotterdam Fragments de gonadotrophine chorionique humaine comme immunorégulateurs
US8680059B2 (en) 1998-05-20 2014-03-25 Biotempt B.V. Oligopeptide acetate and formulations thereof
USRE43279E1 (en) 2000-03-29 2012-03-27 Biotemp B.V. Compositions capable of reducing elevated blood urea concentration
US7358330B2 (en) 2001-03-29 2008-04-15 Biotempt B.V. Immunoregulatory compositions
EP1300418A1 (fr) * 2001-10-04 2003-04-09 Erasmus Universiteit Rotterdam Régulation génétique par des oligopeptides
US7786084B2 (en) 2001-12-21 2010-08-31 Biotempt B.V. Treatment of burns
WO2004100978A1 (fr) * 2003-05-13 2004-11-25 Medvet Science Pty. Ltd. Procede de modulation de la transmigration cellulaire et agents utilises a cet effet
SG163567A1 (en) 2005-07-05 2010-08-30 Biotempt Bv Treatment of tumors
EP1864692A1 (fr) 2006-06-07 2007-12-12 Biotempt B.V. Utilisation de peptides pour la protection contre les radiolésions
US20110082091A1 (en) * 2009-09-28 2011-04-07 Theramab Gmbh Method for Preclinical Testing of Immunomodulatory Drugs

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999025372A1 (fr) * 1997-11-13 1999-05-27 Histatek, Llc Petits peptides et methodes de traitement de l'asthme et de l'inflammation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999025372A1 (fr) * 1997-11-13 1999-05-27 Histatek, Llc Petits peptides et methodes de traitement de l'asthme et de l'inflammation

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ALI H ET AL: "Chemoattractant receptor cross-desensitization.", THE JOURNAL OF BIOLOGICAL CHEMISTRY. UNITED STATES 5 MAR 1999, vol. 274, no. 10, 5 March 1999 (1999-03-05), pages 6027 - 6030, XP002226343, ISSN: 0021-9258 *
DENG X ET AL: "A synthetic peptide derived from human immunodeficiency virus type 1 gp120 downregulates the expression and function of chemokine receptors CCR5 and CXCR4 in monocytes by activating the 7-transmembrane G-protein-coupled receptor FPRL1/LXA4R.", BLOOD. UNITED STATES 15 AUG 1999, vol. 94, no. 4, 15 August 1999 (1999-08-15), pages 1165 - 1173, XP002226344, ISSN: 0006-4971 *
GRONERT K ET AL: "Identification of a human enterocyte lipoxin A4 receptor that is regulated by interleukin (IL)-13 and interferon gamma and inhibits tumor necrosis factor alpha-induced IL-8 release.", THE JOURNAL OF EXPERIMENTAL MEDICINE. UNITED STATES 20 APR 1998, vol. 187, no. 8, 20 April 1998 (1998-04-20), pages 1285 - 1294, XP002226394, ISSN: 0022-1007 *
KANAHO Y ET AL: "COMPARISON OF STIMULATION BY CHEMOTACTIC FORMYL PEPTIDE ANALOGS BETWEEN GTPASE ACTIVITY IN NEUTROPHIL PLASMA MEMBRANES AND GRANULE ENZYME RELEASE FROM INTACT NEUTROPHILS", JOURNAL OF LEUKOCYTE BIOLOGY, vol. 47, no. 5, 1990, pages 420 - 428, XP008012138, ISSN: 0741-5400 *
See also references of WO0129069A1 *
TORRES M ET AL: "Activation of the mitogen-activated protein kinase pathway by fMet-leu-Phe in the absence of Lyn and tyrosine phosphorylation of SHC in transfected cells.", THE JOURNAL OF BIOLOGICAL CHEMISTRY. UNITED STATES 31 MAY 1996, vol. 271, no. 22, 31 May 1996 (1996-05-31), pages 13244 - 13249, XP002226470, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
CN100497374C (zh) 2009-06-10
HUP0203688A2 (hu) 2003-02-28
EA200200451A1 (ru) 2002-10-31
EP1222199A1 (fr) 2002-07-17
CN1633447A (zh) 2005-06-29
AU8014200A (en) 2001-04-30
IL149125A0 (en) 2002-11-10
NO20021732D0 (no) 2002-04-12
CZ20021342A3 (cs) 2003-01-15
CA2387559A1 (fr) 2001-04-26
ZA200202937B (en) 2003-09-23
WO2001029069A1 (fr) 2001-04-26
BR0014742A (pt) 2002-08-27
NO20021732L (no) 2002-06-12
KR20020057972A (ko) 2002-07-12
JP2004507441A (ja) 2004-03-11
PL356096A1 (en) 2004-06-14
MXPA02003782A (es) 2002-12-13

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