EP1157038A4 - Clonage du recepteur 7tm (axor 17) du type p2y - Google Patents

Clonage du recepteur 7tm (axor 17) du type p2y

Info

Publication number
EP1157038A4
EP1157038A4 EP00908675A EP00908675A EP1157038A4 EP 1157038 A4 EP1157038 A4 EP 1157038A4 EP 00908675 A EP00908675 A EP 00908675A EP 00908675 A EP00908675 A EP 00908675A EP 1157038 A4 EP1157038 A4 EP 1157038A4
Authority
EP
European Patent Office
Prior art keywords
axor17
cloning
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00908675A
Other languages
German (de)
English (en)
Other versions
EP1157038A1 (fr
Inventor
Nabil Elshourbagy
Usman Shabon
David Michalovich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9904562.7A external-priority patent/GB9904562D0/en
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP1157038A1 publication Critical patent/EP1157038A1/fr
Publication of EP1157038A4 publication Critical patent/EP1157038A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP00908675A 1999-02-26 2000-02-16 Clonage du recepteur 7tm (axor 17) du type p2y Withdrawn EP1157038A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9904562 1999-02-26
GBGB9904562.7A GB9904562D0 (en) 1999-02-26 1999-02-26 Novel compounds
US30238999A 1999-04-30 1999-04-30
US302389 1999-04-30
PCT/US2000/003951 WO2000050458A1 (fr) 1999-02-26 2000-02-16 Clonage du recepteur 7tm (axor 17) du type p2y

Publications (2)

Publication Number Publication Date
EP1157038A1 EP1157038A1 (fr) 2001-11-28
EP1157038A4 true EP1157038A4 (fr) 2005-01-19

Family

ID=26315191

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00908675A Withdrawn EP1157038A4 (fr) 1999-02-26 2000-02-16 Clonage du recepteur 7tm (axor 17) du type p2y

Country Status (2)

Country Link
EP (1) EP1157038A4 (fr)
WO (1) WO2000050458A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0001700D0 (en) * 2000-01-25 2000-03-15 Glaxo Group Ltd Novel protein
AU2001248755A1 (en) * 2000-04-12 2001-10-23 Takeda Chemical Industries Ltd. Novel g protein-coupled receptor protein and dna thereof
WO2001087937A2 (fr) * 2000-05-18 2001-11-22 Incyte Genomics, Inc. Recepteurs couples aux proteines g
AUPR201500A0 (en) 2000-12-11 2001-01-11 Biosceptre Pty Ltd Methods for identifying pre-neoplastic and neoplastic states in mammals
MY158262A (en) 2001-01-17 2016-09-30 Biosceptre (Aust) Pty Ltd Diagnosis and treatments of cancers and other conditions
WO2003021262A1 (fr) * 2001-08-28 2003-03-13 Takeda Chemical Industries, Ltd. Procede de criblage
WO2003054156A2 (fr) * 2001-12-20 2003-07-03 Aventis Pharmaceuticals Inc. Gave7, nouveau recepteur couple aux proteines g
AU2003300867A1 (en) * 2002-12-19 2004-07-29 Synaptic Pharmaceutical Corporation Uses of the snorf207 receptor
US7524638B1 (en) 2003-06-27 2009-04-28 Osi Pharmaceuticals, Inc. Methods for identification of modulators of OSGPR114 or OSGPR78 activity, and their use in the treatment of disease
WO2006116660A2 (fr) * 2005-04-28 2006-11-02 Amgen Inc. Methodes d'inhibition du gpcr
EP2082032A4 (fr) 2006-10-10 2010-06-30 Biosceptre Int Ltd Hybridomes produisant des anticorps diriges contre le recepteur p2x7 non fonctionnel
NZ583896A (en) 2007-09-14 2011-05-27 Biosceptre Int Ltd Purinergic (p2x) receptors in extra-cellular body fluid
JP5670192B2 (ja) 2007-09-14 2015-02-18 バイオセプター・インターナショナル・リミテッド 新規p2x7エピトープ
JP5701752B2 (ja) 2008-07-04 2015-04-15 バイオセプター・インターナショナル・リミテッド 抗p2x7ペプチドおよびエピトープ
ES2704711T3 (es) 2009-08-20 2019-03-19 Biosceptre Aust Pty Ltd Anticuerpos anti-receptor P2X7 y fragmentos de los mismos
AU2010336032C1 (en) 2009-12-24 2016-04-21 Biosceptre International Limited Antibodies to non-functional oligomeric P2X7 receptors
WO2012031333A1 (fr) 2010-09-10 2012-03-15 Biosceptre International Limited Traitements d'animaux de compagnie
ES2689272T3 (es) 2011-07-01 2018-11-13 Biosceptre (Aust) Pty Ltd Terapia de combinación

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023588A2 (fr) * 1998-10-16 2000-04-27 Millennium Pharmaceuticals, Inc. Recepteurs couples a la proteine g
WO2000031258A2 (fr) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Recepteurs humains couples a la proteine g orphan
DE19930285A1 (de) * 1999-07-02 2001-01-04 Michael Brues P2YLi: Gen, CDNA, Expression und Aminosäuresequenz
WO2001002563A2 (fr) * 1999-07-02 2001-01-11 Sagami Chemical Research Center Proteines humaines ayant des domaines hydrophobes et adn codant pour ces proteines
WO2001004292A1 (fr) * 1999-07-13 2001-01-18 Merck Patent Gmbh Recepteur couple a la proteine g et ses sequences d'adn
EP1090926A1 (fr) * 1999-10-08 2001-04-11 Pfizer Limited Récepteur humain couplé à la proteine G
WO2001031014A2 (fr) * 1999-10-27 2001-05-03 Pharmacia & Upjohn Company Recepteurs couples par des proteines g exprimes dans le cerveau
WO2001042288A2 (fr) * 1999-12-10 2001-06-14 Incyte Genomics, Inc. Recepteurs couples a la proteine g
WO2001048189A1 (fr) * 1999-12-28 2001-07-05 Helix Research Institute Nouveaux recepteurs couples a une proteine de liaison au guanosine triphosphate, genes de ces derniers, et production et utilisation de ces derniers
WO2001055302A2 (fr) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Acides nucleiques, proteines et anticorps
WO2001057188A2 (fr) * 2000-02-03 2001-08-09 Hyseq, Inc. Nouveaux acides nucleiques et polypeptides
GB2360523A (en) * 2000-01-25 2001-09-26 Glaxo Group Ltd A purinergic receptor polypeptide, nucleic acid and its medical uses

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023588A2 (fr) * 1998-10-16 2000-04-27 Millennium Pharmaceuticals, Inc. Recepteurs couples a la proteine g
WO2000031258A2 (fr) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Recepteurs humains couples a la proteine g orphan
DE19930285A1 (de) * 1999-07-02 2001-01-04 Michael Brues P2YLi: Gen, CDNA, Expression und Aminosäuresequenz
WO2001002563A2 (fr) * 1999-07-02 2001-01-11 Sagami Chemical Research Center Proteines humaines ayant des domaines hydrophobes et adn codant pour ces proteines
WO2001004292A1 (fr) * 1999-07-13 2001-01-18 Merck Patent Gmbh Recepteur couple a la proteine g et ses sequences d'adn
EP1090926A1 (fr) * 1999-10-08 2001-04-11 Pfizer Limited Récepteur humain couplé à la proteine G
WO2001031014A2 (fr) * 1999-10-27 2001-05-03 Pharmacia & Upjohn Company Recepteurs couples par des proteines g exprimes dans le cerveau
WO2001042288A2 (fr) * 1999-12-10 2001-06-14 Incyte Genomics, Inc. Recepteurs couples a la proteine g
WO2001048189A1 (fr) * 1999-12-28 2001-07-05 Helix Research Institute Nouveaux recepteurs couples a une proteine de liaison au guanosine triphosphate, genes de ces derniers, et production et utilisation de ces derniers
GB2360523A (en) * 2000-01-25 2001-09-26 Glaxo Group Ltd A purinergic receptor polypeptide, nucleic acid and its medical uses
WO2001055302A2 (fr) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Acides nucleiques, proteines et anticorps
WO2001057188A2 (fr) * 2000-02-03 2001-08-09 Hyseq, Inc. Nouveaux acides nucleiques et polypeptides

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 1 November 1997 (1997-11-01), BOHM, S.K. ET AL.: "P2Y purinoceptor 9 (P2Y9) (Purinergic receptor 9) (G protein-coupled receptor GPR23) (P2Y5-like receptor)", XP002307201, Database accession no. Q99677 *
DATABASE EMBL 11 January 2002 (2002-01-11), XP002307206, Database accession no. ABA08978 *
DATABASE EMBL 12 March 1999 (1999-03-12), OTTENWAELDER, B. ET AL.: "Homo sapiens mRNA, EST DKFZp434B0620_s1 (from clone DKFZp434B0620)", XP002307202, Database accession no. AL042117 *
DATABASE EMBL 17 December 2001 (2001-12-17), XP002307205, Database accession no. AAS39803 *
DATABASE EMBL 21 September 2001 (2001-09-21), XP002307203, Database accession no. AAG64291 *
DATABASE EMBL 21 September 2001 (2001-09-21), XP002307204, Database accession no. AAH49504 *
DATABASE WPI Derwent World Patents Index; AN 2001-425663, XP002307207 *
LEE, D.K. ET AL.: "Discovery and mapping of ten novel G protein-coupled receptor genes", GENE, vol. 275, no. 1, 5 September 2001 (2001-09-05), pages 83 - 91, XP004307114 *
See also references of WO0050458A1 *

Also Published As

Publication number Publication date
WO2000050458A1 (fr) 2000-08-31
EP1157038A1 (fr) 2001-11-28

Similar Documents

Publication Publication Date Title
EP1157038A4 (fr) Clonage du recepteur 7tm (axor 17) du type p2y
HK1029349A1 (en) Kappa receptor opioid peptides
AU1553199A (en) Antagonists of g-protein-coupled receptor
EP1104440A4 (fr) Proteine g couplee au recepteur du 7tm (axor-1)
PL356990A1 (en) Isoxazolecarboxamide derivatives as alpha1-adrenergic receptor antagonists
PL330195A1 (en) Antagonist of dopamine d4 receptor
IL146151A0 (en) Human-g-protein receptor
IL196053A0 (en) Novel human g-protein coupled receptor
IL148515A0 (en) Human g-protein coupled receptor
EP1073681A4 (fr) Clonage du recepteur axor-2 du 7tm
AU1296899A (en) Phenyl-alkyl-imidazoles as h3 receptor antagonists
EP1233981A4 (fr) Recepteur couple a la proteine g
AU6230698A (en) Dopamine d4 receptor antagonist
EP1023295A4 (fr) Promedicaments antagonistes de recepteur de fibrinogene
GB9913850D0 (en) Cloning and expression of a novel receptor
EP1120426A4 (fr) Nouveaux recepteurs couples a la proteine g
GB9927215D0 (en) Hormone receptor expression
AU5344799A (en) Kappa (op2) opioid receptor antagonists
EP1131335A4 (fr) Hlwar77 du recepteur de 7tm
GB9819420D0 (en) Novel receptor
AU6826498A (en) Endotholin receptor antagonists
EP1129101A4 (fr) Nouveau recepteur de 7tm couple a une proteine g (axor15)
GB0107384D0 (en) Molecular cloning of a 7TM receptor (AXOR64)
GB9913649D0 (en) Estrogen receptor
ZA981206B (en) Use of NMDA receptor antagonist

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20010926

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RBV Designated contracting states (corrected)

Designated state(s): GB

REG Reference to a national code

Ref country code: DE

Ref legal event code: 8566

A4 Supplementary search report drawn up and despatched

Effective date: 20041207

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 12N 15/12 A

Ipc: 7C 07K 16/28 B

Ipc: 7C 12Q 1/68 B

Ipc: 7C 07K 14/705 B

Ipc: 7G 01N 33/50 B

Ipc: 7G 01N 33/53 B

Ipc: 7A 61K 48/00 B

Ipc: 7C 12N 5/10 B

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20040302