EP1157038A4 - KLONIERUNG EINES P2Y-äHNLICHEN 7TM-REZEPTORS (AXOR17) - Google Patents

KLONIERUNG EINES P2Y-äHNLICHEN 7TM-REZEPTORS (AXOR17)

Info

Publication number
EP1157038A4
EP1157038A4 EP00908675A EP00908675A EP1157038A4 EP 1157038 A4 EP1157038 A4 EP 1157038A4 EP 00908675 A EP00908675 A EP 00908675A EP 00908675 A EP00908675 A EP 00908675A EP 1157038 A4 EP1157038 A4 EP 1157038A4
Authority
EP
European Patent Office
Prior art keywords
axor17
cloning
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00908675A
Other languages
English (en)
French (fr)
Other versions
EP1157038A1 (de
Inventor
Nabil Elshourbagy
Usman Shabon
David Michalovich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9904562.7A external-priority patent/GB9904562D0/en
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP1157038A1 publication Critical patent/EP1157038A1/de
Publication of EP1157038A4 publication Critical patent/EP1157038A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP00908675A 1999-02-26 2000-02-16 KLONIERUNG EINES P2Y-äHNLICHEN 7TM-REZEPTORS (AXOR17) Withdrawn EP1157038A4 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9904562 1999-02-26
GBGB9904562.7A GB9904562D0 (en) 1999-02-26 1999-02-26 Novel compounds
US30238999A 1999-04-30 1999-04-30
US302389 1999-04-30
PCT/US2000/003951 WO2000050458A1 (en) 1999-02-26 2000-02-16 Cloning of a p2y-like 7tm receptor (axor17)

Publications (2)

Publication Number Publication Date
EP1157038A1 EP1157038A1 (de) 2001-11-28
EP1157038A4 true EP1157038A4 (de) 2005-01-19

Family

ID=26315191

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00908675A Withdrawn EP1157038A4 (de) 1999-02-26 2000-02-16 KLONIERUNG EINES P2Y-äHNLICHEN 7TM-REZEPTORS (AXOR17)

Country Status (2)

Country Link
EP (1) EP1157038A4 (de)
WO (1) WO2000050458A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0001700D0 (en) * 2000-01-25 2000-03-15 Glaxo Group Ltd Novel protein
AU2001248755A1 (en) * 2000-04-12 2001-10-23 Takeda Chemical Industries Ltd. Novel g protein-coupled receptor protein and dna thereof
CA2408134A1 (en) * 2000-05-18 2001-11-22 Incyte Genomics, Inc. G-protein coupled receptors
AUPR201500A0 (en) 2000-12-11 2001-01-11 Biosceptre Pty Ltd Methods for identifying pre-neoplastic and neoplastic states in mammals
PT1360203E (pt) 2001-01-17 2009-04-03 Intreat Pty Ltd Anticorpos de receptor p2x7 não funcional para diagnóstico e tratamento de cancros e outros estados
WO2003021262A1 (fr) * 2001-08-28 2003-03-13 Takeda Chemical Industries, Ltd. Procede de criblage
WO2003054156A2 (en) * 2001-12-20 2003-07-03 Aventis Pharmaceuticals Inc. Novel g proein-coupled receptor, gave7
WO2004060282A2 (en) * 2002-12-19 2004-07-22 Synaptic Pharmaceutical Corporation Uses of the snorf207 receptor
US7524638B1 (en) 2003-06-27 2009-04-28 Osi Pharmaceuticals, Inc. Methods for identification of modulators of OSGPR114 or OSGPR78 activity, and their use in the treatment of disease
WO2006116660A2 (en) * 2005-04-28 2006-11-02 Amgen Inc. Methods of inhibiting a gpr23
AU2007306924A1 (en) 2006-10-10 2008-04-17 Biosceptre International Limited Hybridomas producing antibodies against non functional P2X7 receptor
CA2737126C (en) 2007-09-14 2018-05-01 Biosceptre International Limited Novel p2x7 epitopes
US8293491B2 (en) 2007-09-14 2012-10-23 Biosceptre International Limited Purinergic (P2X) receptors in extra-cellular body fluid
AU2009266430B2 (en) 2008-07-04 2014-08-14 Biosceptre International Limited Anti- P2X7 peptides and epitopes
EP2966090B1 (de) 2009-08-20 2018-10-10 Biosceptre (Aust) Pty Ltd Antikörper gegen den p2x7-rezeptor und fragmente davon
WO2011075789A1 (en) 2009-12-24 2011-06-30 Biosceptre International Limited Antibodies to non-functional oligomeric p2x7 receptors
CN106310245A (zh) 2010-09-10 2017-01-11 生物权威(澳大利亚)有限责任公司 陪伴动物治疗
AU2012278921B2 (en) 2011-07-01 2016-11-10 Biosceptre International Limited Combination therapy

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023588A2 (en) * 1998-10-16 2000-04-27 Millennium Pharmaceuticals, Inc. G-protein coupled receptors
WO2000031258A2 (en) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Human orphan g protein-coupled receptors
DE19930285A1 (de) * 1999-07-02 2001-01-04 Michael Brues P2YLi: Gen, CDNA, Expression und Aminosäuresequenz
WO2001002563A2 (en) * 1999-07-02 2001-01-11 Sagami Chemical Research Center HUMAN PROTEINS HAVING HYDROPHOBIC DOMAINS AND DNAs ENCODING THESE PROTEINS
WO2001004292A1 (en) * 1999-07-13 2001-01-18 Merck Patent Gmbh G-protein coupled receptor and dna sequences thereof
EP1090926A1 (de) * 1999-10-08 2001-04-11 Pfizer Limited Humaner G-Protein gekoppelter Rezeptor
WO2001031014A2 (en) * 1999-10-27 2001-05-03 Pharmacia & Upjohn Company G protein-coupled receptors expressed in human brain
WO2001042288A2 (en) * 1999-12-10 2001-06-14 Incyte Genomics, Inc. G-protein coupled receptors
WO2001048189A1 (fr) * 1999-12-28 2001-07-05 Helix Research Institute Nouveaux recepteurs couples a une proteine de liaison au guanosine triphosphate, genes de ces derniers, et production et utilisation de ces derniers
WO2001055302A2 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
WO2001057188A2 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides
GB2360523A (en) * 2000-01-25 2001-09-26 Glaxo Group Ltd A purinergic receptor polypeptide, nucleic acid and its medical uses

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023588A2 (en) * 1998-10-16 2000-04-27 Millennium Pharmaceuticals, Inc. G-protein coupled receptors
WO2000031258A2 (en) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Human orphan g protein-coupled receptors
DE19930285A1 (de) * 1999-07-02 2001-01-04 Michael Brues P2YLi: Gen, CDNA, Expression und Aminosäuresequenz
WO2001002563A2 (en) * 1999-07-02 2001-01-11 Sagami Chemical Research Center HUMAN PROTEINS HAVING HYDROPHOBIC DOMAINS AND DNAs ENCODING THESE PROTEINS
WO2001004292A1 (en) * 1999-07-13 2001-01-18 Merck Patent Gmbh G-protein coupled receptor and dna sequences thereof
EP1090926A1 (de) * 1999-10-08 2001-04-11 Pfizer Limited Humaner G-Protein gekoppelter Rezeptor
WO2001031014A2 (en) * 1999-10-27 2001-05-03 Pharmacia & Upjohn Company G protein-coupled receptors expressed in human brain
WO2001042288A2 (en) * 1999-12-10 2001-06-14 Incyte Genomics, Inc. G-protein coupled receptors
WO2001048189A1 (fr) * 1999-12-28 2001-07-05 Helix Research Institute Nouveaux recepteurs couples a une proteine de liaison au guanosine triphosphate, genes de ces derniers, et production et utilisation de ces derniers
GB2360523A (en) * 2000-01-25 2001-09-26 Glaxo Group Ltd A purinergic receptor polypeptide, nucleic acid and its medical uses
WO2001055302A2 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
WO2001057188A2 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 1 November 1997 (1997-11-01), BOHM, S.K. ET AL.: "P2Y purinoceptor 9 (P2Y9) (Purinergic receptor 9) (G protein-coupled receptor GPR23) (P2Y5-like receptor)", XP002307201, Database accession no. Q99677 *
DATABASE EMBL 11 January 2002 (2002-01-11), XP002307206, Database accession no. ABA08978 *
DATABASE EMBL 12 March 1999 (1999-03-12), OTTENWAELDER, B. ET AL.: "Homo sapiens mRNA, EST DKFZp434B0620_s1 (from clone DKFZp434B0620)", XP002307202, Database accession no. AL042117 *
DATABASE EMBL 17 December 2001 (2001-12-17), XP002307205, Database accession no. AAS39803 *
DATABASE EMBL 21 September 2001 (2001-09-21), XP002307203, Database accession no. AAG64291 *
DATABASE EMBL 21 September 2001 (2001-09-21), XP002307204, Database accession no. AAH49504 *
DATABASE WPI Derwent World Patents Index; AN 2001-425663, XP002307207 *
LEE, D.K. ET AL.: "Discovery and mapping of ten novel G protein-coupled receptor genes", GENE, vol. 275, no. 1, 5 September 2001 (2001-09-05), pages 83 - 91, XP004307114 *
See also references of WO0050458A1 *

Also Published As

Publication number Publication date
EP1157038A1 (de) 2001-11-28
WO2000050458A1 (en) 2000-08-31

Similar Documents

Publication Publication Date Title
EP1157038A4 (de) KLONIERUNG EINES P2Y-äHNLICHEN 7TM-REZEPTORS (AXOR17)
HRP20000415B1 (en) Kappa receptor opioid peptides
AU1553199A (en) Antagonists of g-protein-coupled receptor
EP1104440A4 (de) Ein g-protein-gekoppelten 7 transmembranrezeptor
PL356990A1 (en) Isoxazolecarboxamide derivatives as alpha1-adrenergic receptor antagonists
PL330195A1 (en) Antagonist of dopamine d4 receptor
IL146151A0 (en) Human-g-protein receptor
IL196053A0 (en) Novel human g-protein coupled receptor
EP1073681A4 (de) Klonierung eines neuen 7-tm-rezeptors, axor-2
IL148515A0 (en) Human g-protein coupled receptor
AU1296899A (en) Phenyl-alkyl-imidazoles as h3 receptor antagonists
EP1233981A4 (de) An ein g-protein gekoppelter rezeptor
AU6230698A (en) Dopamine d4 receptor antagonist
EP1023295A4 (de) Prodrogen von fibrinogenrezeptor-antagonisten
GB9913850D0 (en) Cloning and expression of a novel receptor
EP1120426A4 (de) G-protein-gekoppelte rezeptoren
GB9927215D0 (en) Hormone receptor expression
AU5344799A (en) Kappa (op2) opioid receptor antagonists
EP1131335A4 (de) 7tm rezeptor hlwar77
GB9819420D0 (en) Novel receptor
AU6826498A (en) Endotholin receptor antagonists
EP1129101A4 (de) An den 7tm-rezeptor gekoppeltes g-protein
GB0107384D0 (en) Molecular cloning of a 7TM receptor (AXOR64)
GB9913649D0 (en) Estrogen receptor
ZA981206B (en) Use of NMDA receptor antagonist

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20010926

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RBV Designated contracting states (corrected)

Designated state(s): GB

REG Reference to a national code

Ref country code: DE

Ref legal event code: 8566

A4 Supplementary search report drawn up and despatched

Effective date: 20041207

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 12N 15/12 A

Ipc: 7C 07K 16/28 B

Ipc: 7C 12Q 1/68 B

Ipc: 7C 07K 14/705 B

Ipc: 7G 01N 33/50 B

Ipc: 7G 01N 33/53 B

Ipc: 7A 61K 48/00 B

Ipc: 7C 12N 5/10 B

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20040302