EP1207908A1 - Verfahren zur behandlung von insektenbefall des körpers - Google Patents
Verfahren zur behandlung von insektenbefall des körpersInfo
- Publication number
- EP1207908A1 EP1207908A1 EP00955645A EP00955645A EP1207908A1 EP 1207908 A1 EP1207908 A1 EP 1207908A1 EP 00955645 A EP00955645 A EP 00955645A EP 00955645 A EP00955645 A EP 00955645A EP 1207908 A1 EP1207908 A1 EP 1207908A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- lice
- silicone
- shampoo
- infestation
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N61/00—Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
Definitions
- This invention relates to the safe and effective treatment of lice, nits (and other infestational insects) by using low surface tension lubricants.
- the invention compromises the direct treatment of body insect infestation with a synthetic lubricant, such as food grade silicon, to effectively kill infesting insects such as lice, and nits, as well as fleas, ticks and other insects.
- a synthetic lubricant such as food grade silicon
- the synthetic lubricant is applied directly to the insects, or is provided as a major (more than 50 volume percent) of a shampoo formulation. If added to a shampoo, the exact effective concentration level above 50% is determined based on both the nature of the synthetic lubricant, and the nature of the shampoo used.
- Silicone was directly applied to the hair of three school children, each of which had been infested with lice and nits. Each of the children applied the silicone directly to his or her hair and left it on for five minutes. After five minutes, the hair was washed first with Prell R shampoo and then with Johnson's Baby Shampoo ® . In all three cases the infestation was successfully ended with one application.
- Silicone was directly applied to the hair of twenty school children, each of which had been infested with lice and nits. Each of the children applied the silicone directly to his or her hair and left it on for ten minutes minutes. After ten minutes, the hair was washed with a shampoo of the parent's choice. In all twenty cases the infestation was successfully ended with one application.
- the preferred embodiment for use as a head lice treatment is to use the Silicone in its pure state, that is Dow Corning 200 fluid, 350 CST.
- the Silicone is water white and has a consistency of light syrup. This form is preferred as it clings easily to the hair.
- the Silicone is applied to the entire head, left on for at least ten minutes, and then washed off with any standard shampoo. Within a short time after application of the shampoo, the area is free of any live lice. Any nits do not mature.
- Other embodiments include the processing of synthetic lubricants into a shampoo that effectively kills ticks, fleas, and other insects.
- concentration of such lubricants, and the amount of time they must remain on the affected area is above 50% by volume and is adjusted depending on the type of insect being treated.
- the ticks took longer to die than the lice did in the prior experiments using pure Silicone treatment.
- ten Amblyomma Americanum ticks were coated with Silicone, and ten were coated with Prell " Shampoo.
- the lubricating properties of the silicone provide a morbidity passageway for interfering with insect respiratory and possibly digestive functions, and accordingly other similar lubricants and Silicone derivatives are effective in such insect control.
- head lice the point of entry where the silicone permeates the head lice is very likely the thoracic spiracle, the honeycomb structure which creates maximum surface area and efficient exchange of air and moisture. The nits are likely affected via the head louse nit operculum which contain doughnut shaped holes. See Meinking, T.L. Current Problems in Dermatology 1 1(3) pp 73-120 May/June 1999. With regard to head lice many natural oils treatments have been attempted but with limited efficacy.
- PIB Polyisobutylene
- Krytox 1514 18 6 1. Ryan, T.W. ; Callahan . T.J.; and Dodge, L.G. in Vegetable Oil Fuels, ASAE Conference , 1982 pg. 72
- the surface tension of polydimethylsiloxane at about 20.9 dynes/cm is about 50% lower than the surface tension of most natural oils and is believed to account for its greater ability to penetrate and induce morbidity in insects.
- Krytox® 1514 a fluorinated oil PerFluoroPolyEther (PFPE), with a surface tension of 18, we found that it was also effective in killing lice but slightly less effective than Dow Corning 200 fluid, 350 CST .
- PFPE fluorinated oil PerFluoroPolyEther
- Viscosity or kinematic viscosity is measured in stokes, and is defined to be the dynamic viscosity divided by the density of the liquid; this gives a quantity which depends only on the type of the liquid, independent of its concentration or density.
- Krytoxl 514 has a viscosity of 142 centistokes (cst). while Dow Corning 200 fluid, 350 CST has a viscosity of 350 cst. The viscosity adds to the effectiveness by creating better adhesion of the lubricant to the insects.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14947199P | 1999-08-19 | 1999-08-19 | |
US149471P | 1999-08-19 | ||
PCT/US2000/022577 WO2001013954A1 (en) | 1999-08-19 | 2000-08-17 | Method of treating body insect infestation |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1207908A1 true EP1207908A1 (de) | 2002-05-29 |
EP1207908A4 EP1207908A4 (de) | 2002-09-11 |
Family
ID=22530431
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00955645A Withdrawn EP1207908A4 (de) | 1999-08-19 | 2000-08-17 | Verfahren zur behandlung von insektenbefall des körpers |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1207908A4 (de) |
JP (1) | JP2003507436A (de) |
AU (1) | AU780713B2 (de) |
BR (1) | BR0013437A (de) |
CA (1) | CA2382177C (de) |
IL (1) | IL148138A0 (de) |
MX (1) | MXPA02001759A (de) |
NZ (1) | NZ517149A (de) |
WO (1) | WO2001013954A1 (de) |
ZA (1) | ZA200201195B (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6265384B1 (en) | 1999-01-26 | 2001-07-24 | Dale L. Pearlman | Methods and kits for removing, treating, or preventing lice with driable pediculostatic agents |
WO2001019190A1 (en) | 1999-09-16 | 2001-03-22 | Durminster Limited | Method and composition for the control of arthropods |
US6663876B2 (en) | 2002-04-29 | 2003-12-16 | Piedmont Pharmaceuticals, Llc | Methods and compositions for treating ectoparasite infestation |
GB2470208B (en) * | 2009-05-14 | 2014-01-29 | Thornton & Ross Ltd | A method and composition for the control of ectoparasites |
JP2019081752A (ja) * | 2017-10-30 | 2019-05-30 | アース製薬株式会社 | 吸血性害虫の定着阻害方法及び吸血性害虫の定着阻害剤 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4146619A (en) * | 1977-05-31 | 1979-03-27 | Block Drug Company Inc. | Siloxane toxicants |
US4155995A (en) * | 1973-03-23 | 1979-05-22 | Witco Chemical Corporation | Petroleum based mosquito larvicide |
EP0191543A1 (de) * | 1985-01-15 | 1986-08-20 | Ventec Laboratories, Inc. | Silicongiftstoffe gegen Insekten |
US5045536A (en) * | 1986-06-07 | 1991-09-03 | Baker Ivor P | Liquid formulations |
WO1991015953A1 (en) * | 1990-04-18 | 1991-10-31 | The Procter & Gamble Company | Anti-lice treatment compositions |
WO2001019190A1 (en) * | 1999-09-16 | 2001-03-22 | Durminster Limited | Method and composition for the control of arthropods |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5939809A (ja) * | 1982-08-31 | 1984-03-05 | Shin Etsu Chem Co Ltd | 衛生・農業害虫駆除剤 |
JPH04334305A (ja) * | 1991-05-09 | 1992-11-20 | Mitsubishi Kasei Corp | 殺虫・殺ダニ剤組成物 |
JPH07206615A (ja) * | 1993-11-25 | 1995-08-08 | Dainippon Jochugiku Co Ltd | 防虫剤組成物 |
KR100292708B1 (ko) * | 1995-10-16 | 2001-10-26 | 데이비드 엠 모이어 | 콘디쇼닝샴푸조성물 |
DE19544669A1 (de) * | 1995-11-30 | 1997-06-05 | Bayer Ag | Schädlingsbekämpfungsmittel auf Basis cyclischer Polysiloxane |
-
2000
- 2000-08-17 BR BR0013437-6A patent/BR0013437A/pt not_active Application Discontinuation
- 2000-08-17 IL IL14813800A patent/IL148138A0/xx active IP Right Review Request
- 2000-08-17 NZ NZ517149A patent/NZ517149A/en not_active IP Right Cessation
- 2000-08-17 AU AU67813/00A patent/AU780713B2/en not_active Expired
- 2000-08-17 CA CA2382177A patent/CA2382177C/en not_active Expired - Lifetime
- 2000-08-17 JP JP2001518089A patent/JP2003507436A/ja active Pending
- 2000-08-17 WO PCT/US2000/022577 patent/WO2001013954A1/en active IP Right Grant
- 2000-08-17 EP EP00955645A patent/EP1207908A4/de not_active Withdrawn
- 2000-08-17 MX MXPA02001759A patent/MXPA02001759A/es active IP Right Grant
-
2002
- 2002-02-12 ZA ZA200201195A patent/ZA200201195B/en unknown
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4155995A (en) * | 1973-03-23 | 1979-05-22 | Witco Chemical Corporation | Petroleum based mosquito larvicide |
US4146619A (en) * | 1977-05-31 | 1979-03-27 | Block Drug Company Inc. | Siloxane toxicants |
EP0191543A1 (de) * | 1985-01-15 | 1986-08-20 | Ventec Laboratories, Inc. | Silicongiftstoffe gegen Insekten |
US5045536A (en) * | 1986-06-07 | 1991-09-03 | Baker Ivor P | Liquid formulations |
WO1991015953A1 (en) * | 1990-04-18 | 1991-10-31 | The Procter & Gamble Company | Anti-lice treatment compositions |
WO2001019190A1 (en) * | 1999-09-16 | 2001-03-22 | Durminster Limited | Method and composition for the control of arthropods |
Non-Patent Citations (1)
Title |
---|
See also references of WO0113954A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2382177A1 (en) | 2001-03-01 |
MXPA02001759A (es) | 2003-07-14 |
WO2001013954A1 (en) | 2001-03-01 |
BR0013437A (pt) | 2002-04-30 |
JP2003507436A (ja) | 2003-02-25 |
CA2382177C (en) | 2011-10-11 |
IL148138A0 (en) | 2002-09-12 |
AU780713B2 (en) | 2005-04-14 |
NZ517149A (en) | 2004-01-30 |
ZA200201195B (en) | 2003-04-30 |
AU6781300A (en) | 2001-03-19 |
EP1207908A4 (de) | 2002-09-11 |
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Legal Events
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20041123 |