EP1067930A4 - Antagonistes de l'hormone liberant la gonadotropine (gnrh) - Google Patents
Antagonistes de l'hormone liberant la gonadotropine (gnrh)Info
- Publication number
- EP1067930A4 EP1067930A4 EP99912924A EP99912924A EP1067930A4 EP 1067930 A4 EP1067930 A4 EP 1067930A4 EP 99912924 A EP99912924 A EP 99912924A EP 99912924 A EP99912924 A EP 99912924A EP 1067930 A4 EP1067930 A4 EP 1067930A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- antagonists
- releasing hormone
- gonadotropin releasing
- gonadotropin
- hormone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Transplantation (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8040598P | 1998-04-02 | 1998-04-02 | |
US80405P | 1998-04-02 | ||
GB9815854 | 1998-07-21 | ||
GBGB9815854.6A GB9815854D0 (en) | 1998-07-21 | 1998-07-21 | Antagonists of gonadotropin releasing hormone |
PCT/US1999/006726 WO1999051232A1 (fr) | 1998-04-02 | 1999-03-29 | Antagonistes de l'hormone liberant la gonadotropine (gnrh) |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1067930A1 EP1067930A1 (fr) | 2001-01-17 |
EP1067930A4 true EP1067930A4 (fr) | 2002-09-18 |
Family
ID=26314082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99912924A Withdrawn EP1067930A4 (fr) | 1998-04-02 | 1999-03-29 | Antagonistes de l'hormone liberant la gonadotropine (gnrh) |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1067930A4 (fr) |
JP (1) | JP2002510629A (fr) |
AU (1) | AU3118399A (fr) |
CA (1) | CA2326143A1 (fr) |
WO (1) | WO1999051232A1 (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6534189B1 (en) | 1994-07-15 | 2003-03-18 | Exxonmobil Oil Corporation | Uniaxially shrinkable biaxially oriented polypropylene film and method for use as tobacco pack overwrap |
US6346534B1 (en) | 1998-09-23 | 2002-02-12 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
KR20020039266A (ko) * | 1999-05-14 | 2002-05-25 | 추후기재 | 고나도트로핀 방출 호르몬 수용체 길항제로서의 이미다조-및 피롤로[1,2-a]피리미드-4-온 |
US6537998B1 (en) | 1999-10-15 | 2003-03-25 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
JP2003512379A (ja) * | 1999-10-15 | 2003-04-02 | ニューロクライン バイオサイエンシーズ, インコーポレイテッド | 性腺刺激ホルモン放出ホルモンレセプターアンタゴニストおよびそれに関連する方法 |
OA12514A (en) | 1999-12-24 | 2006-05-29 | Aventis Pharma Ltd | Azaindoles. |
KR100814269B1 (ko) | 2000-01-25 | 2008-03-18 | 뉴로크린 바이오사이언시즈 인코퍼레이티드 | 고나도트로핀-분비 호르몬 수용체 길항제 및 이를 포함하는 약제학적 조성물 |
GB0022670D0 (en) | 2000-09-15 | 2000-11-01 | Astrazeneca Ab | Molecules |
SE0100566D0 (sv) | 2001-02-20 | 2001-02-20 | Astrazeneca Ab | Compounds |
SE0101692D0 (sv) | 2001-05-14 | 2001-05-14 | Astrazeneca Ab | Compounds |
GB0115109D0 (en) | 2001-06-21 | 2001-08-15 | Aventis Pharma Ltd | Chemical compounds |
ATE363481T1 (de) | 2002-08-21 | 2007-06-15 | Astrazeneca Ab | Pyrazolderivate als gnrh-inhibitoren |
ATE384066T1 (de) | 2002-08-21 | 2008-02-15 | Astrazeneca Ab | Thieno-pyrrole verbindungen als antagonisten der gonadotropin-freisetzenden hormonrezeptoren |
TW200407127A (en) | 2002-08-21 | 2004-05-16 | Astrazeneca Ab | Chemical compounds |
TW200413351A (en) | 2002-08-21 | 2004-08-01 | Astrazeneca Ab | Chemical compounds |
GB0219472D0 (en) | 2002-08-21 | 2002-10-02 | Astrazeneca Ab | Chemical compounds |
SE0300908D0 (sv) | 2003-03-31 | 2003-03-31 | Astrazeneca Ab | Azaindole derivatives, preparations thereof, uses thereof and compositions containing them |
WO2008063888A2 (fr) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Composés modulant l'activité de c-fms et/ou de c-kit et utilisations associées |
NZ582772A (en) | 2007-07-17 | 2012-06-29 | Plexxikon Inc | Compounds and methods for kinase modulation, and indications therefor |
SG173178A1 (en) | 2009-04-03 | 2011-09-29 | Hoffmann La Roche | Propane- i-sulfonic acid {3- [5- (4 -chloro-phenyl) -1h-pyrrolo [2, 3-b] pyridine-3-carbonyl] -2, 4-difluoro-pheny l } -amide compositions and uses thereof |
CA2780190C (fr) | 2009-11-06 | 2020-05-05 | Plexxikon, Inc. | Composes et methodes de modulation des kinases et leurs indications d'emploi |
US9624213B2 (en) | 2011-02-07 | 2017-04-18 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
AR085279A1 (es) | 2011-02-21 | 2013-09-18 | Plexxikon Inc | Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico |
US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997021704A1 (fr) * | 1995-12-14 | 1997-06-19 | Merck & Co., Inc. | Antagonistes de l'hormone de liberation de la gonadotropine |
WO1999051233A1 (fr) * | 1998-04-02 | 1999-10-14 | Merck & Co., Inc. | Antagonistes de l'hormone liberant la gonadotropine (gnrh) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2732969B1 (fr) * | 1995-04-14 | 1997-05-16 | Adir | Nouveaux composes pyridiniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
DE69623655T2 (de) * | 1995-10-19 | 2003-04-24 | Takeda Chemical Industries, Ltd. | Chinolinderivate als gnrh antagonisten |
US5849764A (en) * | 1995-12-14 | 1998-12-15 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
-
1999
- 1999-03-29 CA CA002326143A patent/CA2326143A1/fr not_active Abandoned
- 1999-03-29 AU AU31183/99A patent/AU3118399A/en not_active Abandoned
- 1999-03-29 WO PCT/US1999/006726 patent/WO1999051232A1/fr not_active Application Discontinuation
- 1999-03-29 JP JP2000542003A patent/JP2002510629A/ja not_active Withdrawn
- 1999-03-29 EP EP99912924A patent/EP1067930A4/fr not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997021704A1 (fr) * | 1995-12-14 | 1997-06-19 | Merck & Co., Inc. | Antagonistes de l'hormone de liberation de la gonadotropine |
WO1999051233A1 (fr) * | 1998-04-02 | 1999-10-14 | Merck & Co., Inc. | Antagonistes de l'hormone liberant la gonadotropine (gnrh) |
Non-Patent Citations (1)
Title |
---|
See also references of WO9951232A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2326143A1 (fr) | 1999-10-14 |
AU3118399A (en) | 1999-10-25 |
EP1067930A1 (fr) | 2001-01-17 |
WO1999051232A1 (fr) | 1999-10-14 |
JP2002510629A (ja) | 2002-04-09 |
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Legal Events
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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Effective date: 20020802 |
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Free format text: 7A 61K 31/445 A, 7A 61K 31/495 B, 7A 61K 31/50 B, 7A 61K 31/52 B, 7A 61K 31/54 B, 7A 61K 31/505 B, 7A 61K 31/535 B, 7C 07D 401/12 B, 7C 07D 401/14 B, 7C 07D 403/12 B, 7C 07D 519/00 B |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20021001 |