EP1027046A4 - Antagonistes de l'hormone de liberation de la gonadothrophine - Google Patents
Antagonistes de l'hormone de liberation de la gonadothrophineInfo
- Publication number
- EP1027046A4 EP1027046A4 EP98954019A EP98954019A EP1027046A4 EP 1027046 A4 EP1027046 A4 EP 1027046A4 EP 98954019 A EP98954019 A EP 98954019A EP 98954019 A EP98954019 A EP 98954019A EP 1027046 A4 EP1027046 A4 EP 1027046A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- antagonists
- releasing hormone
- gonadotropin releasing
- gonadotropin
- hormone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Gynecology & Obstetrics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6330597P | 1997-10-28 | 1997-10-28 | |
GB9809789 | 1998-05-07 | ||
GBGB9809789.2A GB9809789D0 (en) | 1998-05-07 | 1998-05-07 | Antagonists of gonadotropin releasing hormone |
PCT/US1998/022799 WO1999021553A1 (fr) | 1997-10-28 | 1998-10-27 | Antagonistes de l'hormone de liberation de la gonadothrophine |
US63305P | 2008-01-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1027046A1 EP1027046A1 (fr) | 2000-08-16 |
EP1027046A4 true EP1027046A4 (fr) | 2002-04-03 |
Family
ID=26313619
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP98954019A Withdrawn EP1027046A4 (fr) | 1997-10-28 | 1998-10-27 | Antagonistes de l'hormone de liberation de la gonadothrophine |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1027046A4 (fr) |
JP (1) | JP2001520996A (fr) |
AU (1) | AU1124399A (fr) |
CA (1) | CA2308454A1 (fr) |
WO (1) | WO1999021553A1 (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0017256D0 (en) | 2000-07-13 | 2000-08-30 | Merck Sharp & Dohme | Therapeutic agents |
GB0022670D0 (en) | 2000-09-15 | 2000-11-01 | Astrazeneca Ab | Molecules |
SE0100566D0 (sv) | 2001-02-20 | 2001-02-20 | Astrazeneca Ab | Compounds |
SE0101692D0 (sv) * | 2001-05-14 | 2001-05-14 | Astrazeneca Ab | Compounds |
TW200413351A (en) | 2002-08-21 | 2004-08-01 | Astrazeneca Ab | Chemical compounds |
TW200407127A (en) | 2002-08-21 | 2004-05-16 | Astrazeneca Ab | Chemical compounds |
DE60318716T2 (de) | 2002-08-21 | 2009-01-08 | Astrazeneca Ab | Thieno-pyrrole verbindungen als antagonisten der gonadotropin-freisetzenden hormonrezeptoren |
GB0219472D0 (en) | 2002-08-21 | 2002-10-02 | Astrazeneca Ab | Chemical compounds |
DE60314158T2 (de) | 2002-08-21 | 2008-01-31 | Astrazeneca Ab | Pyrazolderivate als gnrh-inhibitoren |
MXPA06014018A (es) | 2004-06-01 | 2007-02-08 | Hoffmann La Roche | 3-amino-1-arilpropil-indoles como inhibidores de reabsorcion de monoaminas. |
DE102004033902A1 (de) | 2004-07-14 | 2006-02-16 | Zentaris Gmbh | Neue Tetrahydrocarbazolderivate mit verbesserter biologischer Wirkung und verbesserter Löslichkeit als Liganden für G-Protein gekoppelte Rezeptoren (GPCR's) |
JP2009517432A (ja) | 2005-11-30 | 2009-04-30 | エフ.ホフマン−ラ ロシュ アーゲー | 3−アミノ−2−アリールプロピルアザインドールおよびその使用 |
ES2368416T3 (es) | 2005-11-30 | 2011-11-17 | F. Hoffmann-La Roche Ag | Procedimiento para la síntesis de 3-amino-1-arilpropil-indoles. |
RU2008120138A (ru) | 2005-11-30 | 2010-01-10 | Ф. Хоффманн-Ля Рош Аг (Ch) | 3-амино-1-арилпропилиндолы и аза-замещенные индолы |
EP2095818A1 (fr) | 2008-02-29 | 2009-09-02 | AEterna Zentaris GmbH | Utilisation d'antagonistes LHRH dans des doses n'impliquant pas de castration |
US8378107B2 (en) | 2008-10-01 | 2013-02-19 | Panmira Pharmaceuticals, Llc | Heteroaryl antagonists of prostaglandin D2 receptors |
EP2968566A1 (fr) * | 2013-03-15 | 2016-01-20 | AbbVie Inc. | Compositions utiles pour traiter les règles abondantes et les fibromes |
US20170158702A1 (en) * | 2015-12-02 | 2017-06-08 | Kyras Therapeutics, Inc. | Multivalent ras binding compounds |
AU2019353144B2 (en) | 2018-10-05 | 2023-11-16 | Annapurna Bio, Inc. | Compounds and compositions for treating conditions associated with APJ receptor activity |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2181559A1 (en) * | 1972-04-28 | 1973-12-07 | Aec Chimie Organique Bio | N-Phenylalkyl-N-3-indolylalkyl-alkylamines - with sedative, neuroleptic, analgesic, hypotensive, antiserotonin, adrenolytic activity |
GB1562825A (en) * | 1975-10-29 | 1980-03-19 | Lilly Co Eli | N-(2-(5-methoxa-6-halo-indol-3-yl)-ethyl)-amides methods for their preparation and their use |
US4544663A (en) * | 1984-05-07 | 1985-10-01 | Sandoz, Inc. | Indolamine derivatives as anti-fertility agents |
US5030640A (en) * | 1989-01-05 | 1991-07-09 | Merck & Co., Inc. | Novel β-adrenergic agonists and pharmaceutical compositions thereof |
WO1998055119A1 (fr) * | 1997-06-05 | 1998-12-10 | Merck & Co., Inc. | Antagonistes de l'hormone de liberation de la gonadotrophine |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA795239B (en) * | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
US5756507A (en) * | 1995-12-14 | 1998-05-26 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
CA2240108A1 (fr) * | 1995-12-14 | 1997-06-19 | Peter Lin | Antagonistes de l'hormone de liberation de la gonadotropine |
-
1998
- 1998-10-27 EP EP98954019A patent/EP1027046A4/fr not_active Withdrawn
- 1998-10-27 JP JP2000517711A patent/JP2001520996A/ja not_active Withdrawn
- 1998-10-27 CA CA002308454A patent/CA2308454A1/fr not_active Abandoned
- 1998-10-27 AU AU11243/99A patent/AU1124399A/en not_active Abandoned
- 1998-10-27 WO PCT/US1998/022799 patent/WO1999021553A1/fr not_active Application Discontinuation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2181559A1 (en) * | 1972-04-28 | 1973-12-07 | Aec Chimie Organique Bio | N-Phenylalkyl-N-3-indolylalkyl-alkylamines - with sedative, neuroleptic, analgesic, hypotensive, antiserotonin, adrenolytic activity |
GB1562825A (en) * | 1975-10-29 | 1980-03-19 | Lilly Co Eli | N-(2-(5-methoxa-6-halo-indol-3-yl)-ethyl)-amides methods for their preparation and their use |
US4544663A (en) * | 1984-05-07 | 1985-10-01 | Sandoz, Inc. | Indolamine derivatives as anti-fertility agents |
US5030640A (en) * | 1989-01-05 | 1991-07-09 | Merck & Co., Inc. | Novel β-adrenergic agonists and pharmaceutical compositions thereof |
WO1998055119A1 (fr) * | 1997-06-05 | 1998-12-10 | Merck & Co., Inc. | Antagonistes de l'hormone de liberation de la gonadotrophine |
Non-Patent Citations (1)
Title |
---|
See also references of WO9921553A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP1027046A1 (fr) | 2000-08-16 |
JP2001520996A (ja) | 2001-11-06 |
WO1999021553A1 (fr) | 1999-05-06 |
CA2308454A1 (fr) | 1999-05-06 |
AU1124399A (en) | 1999-05-17 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
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Free format text: 7A 61K 31/405 A, 7A 61K 31/35 B, 7C 07D 209/04 B, 7C 07D 209/14 B, 7C 07D 209/42 B, 7A 61P 5/24 B, 7C 07D 453/06 B, 7C 07D 487/08 B |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20020503 |