EP0986385A4 - Antagonistes de gonadoliberine - Google Patents
Antagonistes de gonadoliberineInfo
- Publication number
- EP0986385A4 EP0986385A4 EP98925129A EP98925129A EP0986385A4 EP 0986385 A4 EP0986385 A4 EP 0986385A4 EP 98925129 A EP98925129 A EP 98925129A EP 98925129 A EP98925129 A EP 98925129A EP 0986385 A4 EP0986385 A4 EP 0986385A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- antagonists
- releasing hormone
- gonadotropin releasing
- gonadotropin
- hormone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4873997P | 1997-06-05 | 1997-06-05 | |
US4863497P | 1997-06-05 | 1997-06-05 | |
US48634P | 1997-06-05 | ||
US48739P | 1997-06-05 | ||
GBGB9719841.0A GB9719841D0 (en) | 1997-09-18 | 1997-09-18 | Antagonists of gonadotrophin releasing hormone |
GB9719841 | 1997-09-18 | ||
GB9800450 | 1998-01-09 | ||
GBGB9800450.0A GB9800450D0 (en) | 1998-01-09 | 1998-01-09 | Antagonists of gonadotropin releasing hormone |
PCT/US1998/011207 WO1998055116A1 (fr) | 1997-06-05 | 1998-06-01 | Antagonistes de gonadoliberine |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0986385A1 EP0986385A1 (fr) | 2000-03-22 |
EP0986385A4 true EP0986385A4 (fr) | 2001-05-16 |
Family
ID=27451703
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP98925129A Withdrawn EP0986385A4 (fr) | 1997-06-05 | 1998-06-01 | Antagonistes de gonadoliberine |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0986385A4 (fr) |
JP (1) | JP2002502427A (fr) |
AU (1) | AU728988B2 (fr) |
CA (1) | CA2292881A1 (fr) |
WO (1) | WO1998055116A1 (fr) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6346534B1 (en) | 1998-09-23 | 2002-02-12 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
US6339098B1 (en) | 1999-05-04 | 2002-01-15 | American Home Products Corporation | 2,1-benzisothiazoline 2,2-dioxides |
US6306851B1 (en) | 1999-05-04 | 2001-10-23 | American Home Products Corporation | Cyclocarbamate and cyclic amide derivatives |
US6417214B1 (en) | 1999-05-04 | 2002-07-09 | Wyeth | 3,3-substituted indoline derivatives |
US6380235B1 (en) | 1999-05-04 | 2002-04-30 | American Home Products Corporation | Benzimidazolones and analogues |
US6358948B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators |
US6358947B1 (en) | 1999-05-04 | 2002-03-19 | American Home Products Corporation | Tetracyclic progesterone receptor modulator compounds and methods |
US6329416B1 (en) | 1999-05-04 | 2001-12-11 | American Home Products Corporation | Combination regimens using 3,3-substituted indoline derivatives |
US6423699B1 (en) | 1999-05-04 | 2002-07-23 | American Home Products Corporation | Combination therapies using benzimidazolones |
US6355648B1 (en) | 1999-05-04 | 2002-03-12 | American Home Products Corporation | Thio-oxindole derivatives |
US6369056B1 (en) | 1999-05-04 | 2002-04-09 | American Home Products Corporation | Cyclic urea and cyclic amide derivatives |
US6407101B1 (en) | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
US6399593B1 (en) | 1999-05-04 | 2002-06-04 | Wyeth | Cyclic regimens using cyclic urea and cyclic amide derivatives |
US6319912B1 (en) | 1999-05-04 | 2001-11-20 | American Home Products Corporation | Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides |
US6498154B1 (en) | 1999-05-04 | 2002-12-24 | Wyeth | Cyclic regimens using quinazolinone and benzoxazine derivatives |
US6391907B1 (en) | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
US6444668B1 (en) | 1999-05-04 | 2002-09-03 | Wyeth | Combination regimens using progesterone receptor modulators |
US6462032B1 (en) | 1999-05-04 | 2002-10-08 | Wyeth | Cyclic regimens utilizing indoline derivatives |
US6509334B1 (en) | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
US6380178B1 (en) | 1999-05-04 | 2002-04-30 | American Home Products Corporation | Cyclic regimens using cyclocarbamate and cyclic amide derivatives |
US6537998B1 (en) | 1999-10-15 | 2003-03-25 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
MXPA02006848A (es) | 2000-01-25 | 2002-12-13 | Neurocrine Bioscience Inc | Antagonistas del receptor de la hormona liberadora de gonadotropina. |
UA73119C2 (en) | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
GB0022670D0 (en) | 2000-09-15 | 2000-11-01 | Astrazeneca Ab | Molecules |
SE0100566D0 (sv) | 2001-02-20 | 2001-02-20 | Astrazeneca Ab | Compounds |
SE0101692D0 (sv) | 2001-05-14 | 2001-05-14 | Astrazeneca Ab | Compounds |
WO2003011841A1 (fr) | 2001-08-02 | 2003-02-13 | Neurocrine Biosciences, Inc. | 1,2,4-triazin-3,5-diones comme antagonistes du recepteur de l'hormone de liberation des gonadotrophines (gnrh) |
EP1412363A1 (fr) | 2001-08-02 | 2004-04-28 | Neurocrine Biosciences, Inc. | Antagonistes du recepteur de l'hormone liberatrice de la gonadotropine |
AU2002324586B2 (en) | 2001-08-02 | 2008-04-24 | Neurocrine Biosciences, Inc. | 1,3,5-triazine-2,4,6-triones, preparation and use as gonadotropin-releasing hormone receptor antagonists |
US6939883B2 (en) | 2001-08-02 | 2005-09-06 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
EP1411941A2 (fr) | 2001-08-02 | 2004-04-28 | Neurocrine Biosciences, Inc. | Antagonistes du recepteur de l'hormone liberant la gonadotropine et procedes associes |
EP1453803A2 (fr) * | 2001-12-14 | 2004-09-08 | Zentaris GmbH | Derives tetrahydrocarbazol servant de ligands de recepteurs couples aux proteines g (gpcr) |
DE10164564B4 (de) | 2001-12-14 | 2007-05-16 | Zentaris Gmbh | Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR) |
TW200413351A (en) | 2002-08-21 | 2004-08-01 | Astrazeneca Ab | Chemical compounds |
TW200407127A (en) | 2002-08-21 | 2004-05-16 | Astrazeneca Ab | Chemical compounds |
US7253290B2 (en) | 2002-08-21 | 2007-08-07 | Astrazeneca Ab | Pyrazole derivatives as GnRH inhibitors |
AU2003267551A1 (en) | 2002-08-21 | 2004-03-11 | Astrazeneca Ab | Thieno-pyrrole compounds as antagonists of gonadotropin releasing hormone |
GB0219472D0 (en) | 2002-08-21 | 2002-10-02 | Astrazeneca Ab | Chemical compounds |
US7056927B2 (en) | 2003-07-07 | 2006-06-06 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
US7015226B2 (en) | 2003-07-07 | 2006-03-21 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
ATE428427T1 (de) | 2003-07-07 | 2009-05-15 | Neurocrine Biosciences Inc | Pyrimidin-2,4-dion-derivate als gonadotropin freisetzende hormon-rezeptor-antagonisten |
DE102004033902A1 (de) | 2004-07-14 | 2006-02-16 | Zentaris Gmbh | Neue Tetrahydrocarbazolderivate mit verbesserter biologischer Wirkung und verbesserter Löslichkeit als Liganden für G-Protein gekoppelte Rezeptoren (GPCR's) |
GB0506759D0 (en) * | 2005-04-02 | 2005-05-11 | Medical Res Council | Combination treatment methods |
EP2095818A1 (fr) | 2008-02-29 | 2009-09-02 | AEterna Zentaris GmbH | Utilisation d'antagonistes LHRH dans des doses n'impliquant pas de castration |
TW201130854A (en) | 2009-12-22 | 2011-09-16 | Bayer Schering Pharma Ag | Pyridinone derivatives and pharmaceutical compositions thereof |
WO2012175514A1 (fr) | 2011-06-21 | 2012-12-27 | Bayer Intellectual Property Gmbh | Dérivés de pyridinone et compositions pharmaceutiques les contenant |
JP2017529388A (ja) | 2014-08-26 | 2017-10-05 | ベタニエン ホスピタル | 炎症性病態の治療のための方法、薬剤および組成物 |
CN113574607A (zh) | 2019-03-11 | 2021-10-29 | 甘布罗伦迪亚股份公司 | 估计透析患者体内物质的生成率 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997021704A1 (fr) * | 1995-12-14 | 1997-06-19 | Merck & Co., Inc. | Antagonistes de l'hormone de liberation de la gonadotropine |
WO1997021707A1 (fr) * | 1995-12-14 | 1997-06-19 | Merck & Co., Inc. | Antagonistes de la gonadoliberine |
WO1997021435A1 (fr) * | 1995-12-14 | 1997-06-19 | Merck & Co., Inc. | Antagonistes de la gonadoliberine |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA795239B (en) * | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
US5245046A (en) * | 1988-11-14 | 1993-09-14 | The Upjohn Company | α-amino-indole-3-acetic acids useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents |
-
1998
- 1998-06-01 JP JP50271699A patent/JP2002502427A/ja active Pending
- 1998-06-01 EP EP98925129A patent/EP0986385A4/fr not_active Withdrawn
- 1998-06-01 AU AU77149/98A patent/AU728988B2/en not_active Ceased
- 1998-06-01 WO PCT/US1998/011207 patent/WO1998055116A1/fr not_active Application Discontinuation
- 1998-06-01 CA CA002292881A patent/CA2292881A1/fr not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997021704A1 (fr) * | 1995-12-14 | 1997-06-19 | Merck & Co., Inc. | Antagonistes de l'hormone de liberation de la gonadotropine |
WO1997021707A1 (fr) * | 1995-12-14 | 1997-06-19 | Merck & Co., Inc. | Antagonistes de la gonadoliberine |
WO1997021435A1 (fr) * | 1995-12-14 | 1997-06-19 | Merck & Co., Inc. | Antagonistes de la gonadoliberine |
Non-Patent Citations (1)
Title |
---|
See also references of WO9855116A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU728988B2 (en) | 2001-01-25 |
AU7714998A (en) | 1998-12-21 |
EP0986385A1 (fr) | 2000-03-22 |
JP2002502427A (ja) | 2002-01-22 |
CA2292881A1 (fr) | 1998-12-10 |
WO1998055116A1 (fr) | 1998-12-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0986385A4 (fr) | Antagonistes de gonadoliberine | |
EP0986557A4 (fr) | Antagonistes de la gonadoliberine | |
IL124554A0 (en) | Antagonists of gonadotropin releasing hormone | |
IL124613A0 (en) | Antagonists of gonadotropin releasing hormone | |
EP0868178A4 (fr) | Antagonistes de la gonadoliberine | |
EP0918522A4 (fr) | Antagonistes de la gonadoliberine | |
AU3008997A (en) | Antagonists of gonadotropin releasing hormone | |
ZA9610535B (en) | Antagonists of gonadotropin releasing hormone. | |
ZA9610536B (en) | Antagonists of gonadotropin releasing hormone. | |
EP1011667A4 (fr) | Antagonistes de l'hormone de liberation de la gonadotrophine | |
EP1067930A4 (fr) | Antagonistes de l'hormone liberant la gonadotropine (gnrh) | |
EP1027046A4 (fr) | Antagonistes de l'hormone de liberation de la gonadothrophine | |
EP0901471A4 (fr) | Antagonistes de la gonadoliberine | |
EP0920319A4 (fr) | Antagonistes de la gonadoliberine | |
EP1049472A4 (fr) | Antagonistes de la gonadoliberine | |
AU4834900A (en) | Antagonists of gonadotropin releasing hormone | |
EP1062215A4 (fr) | Antagonistes de l'hormone de liberation de la gonadotrophine | |
GB9719386D0 (en) | Antagonists of gonadotropin releasing hormone | |
GB9719387D0 (en) | Antagonists of gonadotropin releasing hormone | |
GB9719391D0 (en) | Antagonists of gonadotropin releasing hormone | |
GB9719840D0 (en) | Antagonists of gonadotropin releasing hormone | |
GB9612796D0 (en) | Antagonists of gonadotropin releasing hormone | |
GB9612084D0 (en) | Antagonists of gonadotropin releasing hormone | |
GB9603344D0 (en) | Antagonists of gonadotropin releasing hormone | |
GB9603369D0 (en) | Antagonists of gonadotropin releasing hormone |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20000105 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7A 61K 31/40 A, 7A 61K 31/44 B, 7C 07D 213/73 B, 7C 07D 407/06 B, 7A 61P 5/02 B, 7A 61P 5/24 B, 7A 61P 15/00 B, 7A 61P 15/12 B, 7A 61P 25/00 B, 7A 61P 43/00 B |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20010330 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20030102 |